EKS-MUP-00228

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00228

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	365.0	2.3E-109	162	422	261

Status

Unreviewed

Ensembl Protein

ENSMPUP00000007957

UniProt Accession

G9K9G4;

Protein Name

Protein Synonyms/Alias

Mitogen-activated protein kinase kinase 7;

Gene Name

Map2k7

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000008015	ENSMPUP00000007957	ENSMPUT00000008082

Organism

Mustela putorius furo

Functional Description

Protein Length

461

Protein Sequence
(FASTA)

MCVCVSSIHP PGPAISVGFY PSLQFGASRL TPLPHYDLIS FLLNKSVVSV VIYRGVVFFF 60

FLPFPHPVIV ITLSPAPAPS QRAALQLPLA NDGGSRSPCS ESSPQHPTPP ARPRNMLGLP 120

STLFMPRSME SIEIDQKLQE IMKQTGYLTI GGQRYQAEIN DLENLGEMGS GTCGQVWKMR 180

FRKTGHVIAV KQMRRSGNKE ENKRILMDLD VVLKSHDCPY IVQCFGTFIT NTDVFIAMEL 240

MGTCAEKLKK RVQGPIPERI LGKMTVAIVK ALYYLKEKHG VIHRDVKPSN ILLDERGQIK 300

LCDFGISGRL VDSKAKTRSA GCAAYMAPER IDPPDPTKPD YDIRADVWSL GISLVELATG 360

QFPYKNCKTD FEVLTKVLQE EPPLLPGHMG FSGDFQSFVK DCLTKDHRKR PKYNKLLEHS 420

FIKRYEMLEV DVASWFKDVM AKTESPRTSG VLSQHHLPFF R 461

Nucleotide Sequence
(FASTA)

ATGTGTGTCT GTGTCAGCTC CATCCATCCT CCCGGTCCTG CCATTTCTGT CGGTTTCTAC 60

CCGTCTCTGC AGTTTGGAGC CTCGCGCCTC ACCCCTCTTC CTCATTATGA TTTGATTTCT 120

TTTCTTTTGA ACAAATCAGT TGTTTCTGTT GTGATTTATC GTGGTGTTGT TTTTTTTTTT 180

TTTCTTCCTT TTCCCCATCC AGTTATTGTG ATCACTCTAA GCCCTGCTCC TGCCCCGTCC 240

CAACGAGCAG CCCTCCAGCT CCCGCTGGCC AATGATGGGG GCAGCCGCTC ACCGTGCTCC 300

GAGAGCTCCC CACAGCACCC CACACCCCCT GCCCGGCCCC GCAACATGCT GGGGCTTCCA 360

TCAACCTTGT TCATGCCCCG CAGCATGGAG AGCATTGAGA TTGACCAGAA GCTACAGGAG 420

ATCATGAAGC AGACCGGCTA CCTGACCATC GGGGGCCAGC GCTACCAGGC CGAAATCAAC 480

GATCTGGAGA ACCTGGGGGA GATGGGCAGC GGCACTTGCG GCCAGGTGTG GAAGATGCGC 540

TTCCGGAAGA CGGGCCACGT CATCGCCGTC AAGCAAATGC GGCGCTCGGG AAACAAGGAG 600

GAGAACAAGC GGATCCTCAT GGACCTGGAC GTGGTGCTCA AGAGCCACGA CTGCCCCTAC 660

ATCGTGCAGT GCTTCGGCAC GTTTATCACC AACACGGACG TCTTCATCGC CATGGAGCTC 720

ATGGGCACAT GTGCGGAGAA GCTCAAGAAG CGGGTGCAGG GCCCCATCCC CGAGCGGATC 780

CTGGGCAAGA TGACGGTGGC GATCGTGAAG GCGCTGTACT ACCTGAAGGA GAAGCACGGC 840

GTGATCCACC GAGACGTCAA GCCCTCGAAC ATCCTGCTGG ACGAGCGGGG CCAGATCAAG 900

CTCTGTGACT TTGGCATCAG CGGACGTTTG GTCGATTCCA AGGCCAAGAC GCGCAGCGCC 960

GGCTGTGCCG CGTACATGGC GCCGGAGCGC ATAGACCCTC CGGACCCCAC CAAGCCGGAC 1020

TATGACATCC GGGCCGACGT ATGGAGCCTG GGCATATCCT TGGTGGAGCT AGCGACGGGA 1080

CAGTTTCCCT ACAAGAACTG CAAGACAGAC TTTGAGGTCC TTACCAAAGT CCTCCAGGAA 1140

GAGCCCCCGC TCTTGCCCGG GCACATGGGC TTCTCAGGGG ACTTCCAGTC CTTTGTCAAA 1200

GACTGCCTTA CTAAGGATCA CAGGAAGAGA CCAAAGTATA ATAAGCTACT TGAACACAGC 1260

TTCATCAAGC GCTACGAGAT GCTGGAGGTG GACGTGGCGT CCTGGTTCAA GGACGTCATG 1320

GCGAAGACCG AGTCACCGAG GACGAGTGGA GTCCTGAGCC AGCACCACCT GCCCTTCTTC 1380

AGGTAG 1386

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le+l+e+G+G++g+V+k++++k+g+++avK++r++ +kee+k+il++l+v+ ks+++pyi

Q: 162   LENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYI  221

         7899********************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+++G+f++++dv+i+melm  t+ +k+ k+v   ++ ipe++lgk++va+vkal ylke

Q: 222   VQCFGTFITNTDVFIAMELMG-TCAEKLKKRV---QGPIPERILGKMTVAIVKALYYLKE  277

         *********************.*****99996...9************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg....  175

         k+ +iHRDvKPsNiL++++G++KlCDFG+sg+lvds Ak++ +G+++YmaPEri++

Q: 278   KHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRsAGCAAYMAPERIDPpdpt  337

         *******************************************************99999

S: 176   kkkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpee.efseefqe  234

         k++Y++++dvWslG++lvelatg++py+++k+++e+l+++++eepp lp +  fs +fq+

Q: 338   KPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHmGFSGDFQS  397

         9************************************************9999*******

S: 235   fvskClkkdekeRpklkellkhafi  259

         fv++Cl+kd+++Rpk+++ll+h+fi

Q: 398   FVKDCLTKDHRKRPKYNKLLEHSFI  422

         ***********************97

Domain Sequence
(FASTA)

LENLGEMGSG TCGQVWKMRF RKTGHVIAVK QMRRSGNKEE NKRILMDLDV VLKSHDCPYI 60

VQCFGTFITN TDVFIAMELM GTCAEKLKKR VQGPIPERIL GKMTVAIVKA LYYLKEKHGV 120

IHRDVKPSNI LLDERGQIKL CDFGISGRLV DSKAKTRSAG CAAYMAPERI DPPDPTKPDY 180

DIRADVWSLG ISLVELATGQ FPYKNCKTDF EVLTKVLQEE PPLLPGHMGF SGDFQSFVKD 240

CLTKDHRKRP KYNKLLEHSF I 261

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0000287	; F:magnesium ion binding
GO:0004708	; F:MAP kinase kinase activity
GO:0007257	; P:activation of JUN kinase activity

KEGG

InterPros

IPR011009

; Kinase-like_dom.

Pfam

SMARTs

Prosites

Prints

Created Date

20-Feb-2013