EKS-MUP-00335

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00335

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PEK	360.4	6.6E-108	590	1010	421

Status

Unreviewed

Ensembl Protein

ENSMPUP00000008237

Gene Name

Eif2ak4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000008299	ENSMPUP00000008237	ENSMPUT00000008368

Organism

Mustela putorius furo

Protein Length

1657

Protein Sequence
(FASTA)

MAGGRGGPGR GRDEPPESYP QRQEHELQAL EAIYGADFQD LRPAAGKSVT EPPEINLVLY 60

PQGLTGEEVY VQVDLRVRCP PTYPDVVPEI ELKNAKGLSN ESVNLLKSHL EKVAKKHCGE 120

VMIFELADHV QSFLSEHNKP PPKSFHEEML ERRAQEEQRR LLEAKQKVEQ EQREILHEIQ 180

RRKEEIKEER KRKEMAKQER LEIANLSNQD QNSRKDPGGH RPSAILHGGS PDFVGNGKHR 240

TNSSGRSRRE RQYSVCSSED SPGSCEVLYF SLGSPDQLMV YKGKCIGSDE PLGKLVYNAL 300

ETATGSFVLL HEWVLQWQKK MGPFLTSQEK EKIDKCKKQI QGAETEFSSL VKLSHPNVIR 360

YFAMNLKEQD DSIIVDILSE HVNGVSLTAH LSHSGPIPVH QLRRYAAQLL SGLEYLHSND 420

VVHKDLRASN VLVDADGNVK VTDYSISKRL ADICKEDVFE QSRVSFSDSA LPYKTGKKGD 480

VWCLGLLLLF LSQGQECGAY PVTIPHDLPA DFRDFLKKCV CLDDKERWSA QQLLKHSFIN 540

PQPKMSLLEQ SPEDSGGQDY VETVIPRKQL PSAAFFTETQ RQFSRYFIEF EELQLLGKGA 600

FGAVIKVQNK LDGCCYAVKR IPINPASRHF RRIKGEVTLL SRLHHENIVR YYNAWIERYE 660

RPVGSAMLPP DSDSDSRPQT WDAPAPSQQP VCCGGPNGPG SVEAAAPPPI LSSVEWSTSG 720

ERSASARFQP AGPGSSSDEE DDDDEDDDED EHEGMFRQPF LPASDSDSDI IFEDENSKSQ 780

NQNEDCNGKN SCHESEPSAV VEAVHYLYIQ MEYCEKSTLR DTIDQGLYLD TVRLWRLFRE 840

ILDGLAYIHE KGMIHRDLKP VNIFLDSDDH VKIGDFGLAT DHLAFTADGK QDDTADHSIK 900

SDPSGHLTGM VGTALYVSPE IQGSSRPTYN QKVDLFSLGI IFFEMSYHPM VTASERIFVL 960

NQLRDPTSPK FPEDFDDGEH TKQKSVISWL LNHDPAKRPT ATELLKSELL PPPQMEESEL 1020

HEVLHHTLAN VDGKAYRTMM AHIFSQRISP AIDYTYDSNM PKSFSIRTSK IQQHVCDTIV 1080

RVFKRHGAVQ LCTPLLLPQN RQIYEHNEAA LFVDHSGMLV MLPFDLRIPF ARYVARNNIL 1140

NLKRYCIERV FRPRKLDRFH PKELLECAFD IVTSAANSSL PTAEVIYTIC EIIQEFPALQ 1200

EKNYSIYLNH TMLLKAILLH CGIPEDKLSQ VYVILYDAVT EKLTRREMEA KFCNLSLSSN 1260

SLCRLYKFIE QKGDLQDLTP AINSLIKQKT GIAQLVKYGL KDLEEIVGLL KKLGIKLQVL 1320

INLGLVYKVQ QHNGVIFQFA AVIRRRQRAV SEILAAGGRY DLLIPQFRGP QALGPVPTAV 1380

GVSIAIDKIS VAILNMEEPV TISSCDLLIV SVGQMSMSRA INLTQKLWSA GITAQIMYDW 1440

SQSQEELQEY CRHHEITCVA LVSDKGGSYV KVKSFEKERQ TEKHVQESDL IDHVLQKLRT 1500

KVSDERTIRE ASDNLAVQNL KGSFSNASGL FEIHGAAVVP IVSVIAPEKL SASTRRRYET 1560

QVQTRLQTSL ANLHQKSSEI EILAVDLPKE TILQFLSLEW DADEQAFNTT VKQLLSRLPK 1620

QRYLKLVCDE IYNIKVEKKV SVLFLYSYRD DYYRILF 1657

Nucleotide Sequence
(FASTA)

ATGGCTGGGG GCCGTGGGGG CCCCGGGCGC GGCCGGGACG AGCCGCCGGA GAGCTACCCA 60

CAGCGTCAGG AGCACGAGCT GCAGGCTCTG GAGGCCATCT ACGGCGCCGA CTTCCAGGAC 120

CTGCGACCGG CCGCGGGCAA ATCGGTCACC GAGCCCCCTG AAATCAATTT AGTTCTGTAC 180

CCTCAGGGCC TGACTGGTGA AGAAGTATAC GTGCAAGTGG ATTTGAGGGT TAGATGCCCA 240

CCGACCTACC CAGACGTAGT CCCTGAAATA GAGTTAAAGA ATGCCAAAGG TCTGTCAAAT 300

GAAAGTGTTA ATTTATTAAA ATCCCATCTA GAGAAAGTGG CCAAAAAACA TTGTGGAGAG 360

GTGATGATAT TTGAACTGGC CGACCACGTG CAGTCATTTC TCAGCGAGCA TAACAAGCCC 420

CCTCCCAAGT CTTTCCATGA AGAAATGCTA GAAAGGCGGG CTCAGGAAGA GCAGCGGAGG 480

CTGTTGGAGG CCAAGCAGAA GGTGGAACAG GAGCAACGTG AGATCCTTCA TGAGATTCAG 540

AGAAGGAAAG AAGAGATCAA AGAAGAGAGA AAAAGAAAAG AAATGGCTAA GCAGGAGCGT 600

TTGGAAATTG CTAATTTATC AAACCAAGAT CAGAACTCTA GGAAAGACCC AGGAGGACAC 660

AGACCGTCTG CCATTCTACA TGGAGGCTCT CCGGACTTTG TGGGAAATGG CAAACATCGG 720

ACCAACTCTT CCGGAAGGTC AAGGCGAGAA CGTCAGTATT CTGTATGTAG TAGTGAAGAT 780

TCTCCCGGGT CTTGTGAAGT CCTGTATTTC TCCCTGGGTA GTCCTGATCA GCTCATGGTT 840

TACAAGGGGA AATGCATTGG CAGTGATGAG CCCCTTGGAA AGTTAGTTTA CAATGCTTTG 900

GAAACAGCCA CTGGCAGCTT TGTCTTGTTG CACGAGTGGG TCCTTCAGTG GCAGAAGAAA 960

ATGGGTCCGT TCCTCACCAG TCAAGAAAAG GAGAAGATCG ATAAGTGCAA AAAGCAGATT 1020

CAAGGGGCAG AGACGGAATT CAGCTCACTG GTAAAACTGA GCCACCCAAA TGTCATACGC 1080

TACTTTGCAA TGAATCTCAA AGAGCAAGAT GACTCCATCA TAGTGGACAT TTTATCAGAG 1140

CACGTGAATG GGGTCTCCCT CACCGCACAC CTGAGCCACT CTGGCCCCAT CCCCGTGCAT 1200

CAGCTCCGCA GGTATGCAGC TCAGCTCTTG TCGGGCCTCG AGTATTTGCA CAGCAATGAC 1260

GTGGTGCACA AGGATCTGCG TGCATCAAAT GTGCTGGTGG ACGCAGACGG CAATGTCAAG 1320

GTTACGGACT ACAGCATTTC TAAGCGCCTA GCAGACATTT GCAAGGAAGA CGTGTTTGAA 1380

CAAAGCCGAG TTAGTTTTAG TGATAGTGCC TTACCTTATA AAACGGGCAA GAAAGGGGAT 1440

GTTTGGTGTC TTGGTCTTCT GCTGCTCTTC CTCAGCCAAG GACAAGAATG TGGAGCGTAC 1500

CCCGTGACCA TCCCTCATGA CTTACCAGCT GACTTTCGAG ATTTTCTGAA GAAGTGTGTG 1560

TGCTTGGACG ACAAGGAGAG ATGGAGTGCC CAGCAGCTGT TGAAACACAG CTTTATCAAT 1620

CCTCAGCCAA AAATGTCTTT GTTGGAACAA AGTCCTGAAG ATTCTGGAGG ACAGGATTAT 1680

GTTGAGACTG TTATTCCTAG GAAGCAGCTA CCCAGCGCAG CATTCTTCAC TGAGACCCAG 1740

AGACAGTTCT CCCGGTATTT CATTGAGTTT GAAGAACTAC AGCTTCTCGG CAAAGGAGCC 1800

TTTGGAGCTG TCATCAAGGT GCAGAACAAG CTGGATGGCT GCTGCTACGC AGTGAAGCGC 1860

ATCCCCATCA ACCCGGCCAG CAGGCACTTC CGCAGGATCA AGGGCGAGGT GACACTGCTG 1920

TCGCGCCTGC ATCATGAGAA CATCGTGCGC TACTACAATG CCTGGATTGA GAGATATGAG 1980

CGGCCGGTGG GCTCGGCGAT GCTGCCCCCG GACTCGGACT CGGACTCACG GCCCCAAACA 2040

TGGGATGCGC CAGCTCCGTC CCAGCAGCCG GTGTGCTGCG GCGGGCCTAA TGGCCCCGGC 2100

AGCGTGGAGG CGGCCGCGCC CCCGCCCATC CTCAGCTCGG TGGAGTGGAG CACGTCGGGC 2160

GAGCGCTCGG CCAGCGCCCG CTTCCAGCCC GCCGGCCCGG GCTCCAGCAG CGACGAGGAG 2220

GACGACGACG ATGAGGACGA CGACGAGGAC GAGCACGAGG GCATGTTCCG GCAACCATTC 2280

CTACCTGCTT CAGATTCTGA CAGCGATATC ATCTTTGAAG ATGAGAACAG TAAGAGTCAG 2340

AATCAGAATG AAGACTGCAA TGGGAAGAAC AGTTGCCATG AAAGTGAGCC ATCAGCTGTT 2400

GTTGAAGCTG TGCATTATCT GTATATCCAG ATGGAGTACT GTGAGAAGAG CACTTTGCGT 2460

GACACCATTG ACCAGGGGCT ATATCTGGAC ACTGTCAGAC TCTGGAGGCT TTTTCGAGAG 2520

ATTCTGGATG GATTGGCATA TATCCATGAG AAAGGAATGA TTCACCGGGA TTTAAAGCCT 2580

GTCAACATTT TTTTAGATTC CGATGACCAT GTCAAAATAG GTGATTTTGG TTTAGCAACA 2640

GACCATCTGG CCTTCACTGC TGATGGCAAG CAAGATGATA CGGCAGATCA CTCGATTAAA 2700

TCAGACCCCT CAGGCCATCT GACTGGAATG GTTGGTACTG CTTTATATGT AAGCCCAGAG 2760

ATCCAAGGAA GCAGTAGACC CACGTACAAC CAGAAAGTGG ATCTCTTCAG CCTGGGAATT 2820

ATCTTCTTTG AGATGTCCTA TCACCCCATG GTCACGGCCT CAGAAAGGAT CTTTGTCCTC 2880

AACCAACTCA GAGATCCCAC TTCGCCTAAG TTTCCAGAAG ACTTCGATGA TGGAGAGCAT 2940

ACAAAGCAGA AATCGGTCAT CTCCTGGCTA TTGAACCACG ATCCCGCCAA GCGGCCTACA 3000

GCCACAGAAC TGCTCAAGAG CGAGCTGCTG CCCCCACCCC AGATGGAGGA GTCGGAGCTA 3060

CACGAAGTTC TGCACCACAC CCTAGCCAAC GTGGATGGGA AGGCCTACCG CACCATGATG 3120

GCCCACATCT TCTCTCAACG CATCTCCCCA GCCATCGACT ACACCTATGA CAGCAACATG 3180

CCAAAGAGCT TCTCAATCCG AACATCCAAG ATACAGCAAC ACGTGTGTGA CACCATCGTC 3240

CGTGTTTTTA AAAGACATGG AGCTGTCCAG TTGTGTACCC CACTGCTGCT TCCACAGAAT 3300

AGGCAAATAT ACGAACACAA TGAAGCTGCC TTATTCGTGG ACCACAGCGG AATGCTGGTG 3360

ATGCTTCCTT TCGACCTGCG GATTCCTTTT GCAAGATACG TGGCAAGAAA TAATATATTG 3420

AATTTGAAAC GGTACTGCAT AGAGCGTGTG TTCAGGCCTC GCAAGTTAGA CCGATTTCAT 3480

CCCAAAGAGC TTCTGGAATG TGCATTCGAT ATCGTCACGT CTGCTGCCAA CAGCTCTCTG 3540

CCCACTGCCG AAGTCATCTA CACGATCTGT GAGATCATCC AGGAGTTCCC GGCGCTTCAG 3600

GAAAAAAATT ATAGTATTTA CTTGAACCAT ACCATGTTAT TGAAAGCAAT CCTCTTACAC 3660

TGTGGAATCC CAGAAGATAA ACTCAGTCAA GTCTATGTTA TTCTGTATGA TGCCGTGACA 3720

GAAAAGCTGA CGAGGAGAGA AATGGAAGCC AAGTTTTGTA ATCTGTCTTT GTCGTCTAAT 3780

AGTCTGTGTC GACTCTACAA ATTTATTGAG CAGAAGGGAG ATTTGCAGGA TCTAACGCCA 3840

GCAATAAATT CATTAATAAA ACAGAAAACA GGCATTGCCC AACTGGTGAA GTATGGCTTA 3900

AAAGACCTAG AAGAGATTGT TGGGCTGTTG AAGAAACTTG GCATCAAGTT GCAGGTCTTG 3960

ATCAATCTGG GCCTGGTATA CAAGGTACAG CAGCACAATG GAGTCATCTT CCAGTTTGCG 4020

GCAGTCATCA GACGCAGGCA GAGGGCTGTA TCGGAAATCC TGGCAGCTGG TGGCAGATAC 4080

GACCTGCTGA TTCCCCAGTT TAGAGGACCA CAGGCTCTGG GACCAGTCCC CACTGCTGTT 4140

GGGGTGAGCA TAGCTATAGA CAAGATCTCT GTGGCGATCC TCAACATGGA AGAACCTGTT 4200

ACAATCAGCT CTTGTGACCT CCTAATTGTA AGTGTTGGCC AGATGTCCAT GTCCCGGGCC 4260

ATCAACCTCA CCCAGAAGCT CTGGTCTGCA GGAATCACGG CACAAATCAT GTATGACTGG 4320

TCACAGTCCC AAGAGGAACT ACAAGAATAT TGCAGACACC ACGAAATCAC GTGCGTGGCC 4380

CTCGTCTCAG ATAAAGGAGG AAGCTATGTC AAGGTTAAGT CTTTTGAGAA GGAAAGGCAA 4440

ACAGAGAAAC ATGTGCAGGA GTCTGATCTT ATAGACCACG TTTTGCAGAA ACTCAGAACT 4500

AAAGTCAGTG ATGAAAGAAC TATCAGAGAA GCTTCTGATA ATCTTGCAGT GCAAAATCTG 4560

AAGGGGTCCT TTTCTAATGC TTCAGGTTTG TTTGAAATCC ATGGAGCTGC AGTTGTACCC 4620

ATTGTGAGTG TGATAGCCCC AGAGAAGCTG TCAGCCAGCA CTCGGAGGCG ATATGAAACT 4680

CAGGTACAAA CACGACTTCA GACCTCCCTT GCCAACTTAC ATCAGAAAAG CAGTGAAATT 4740

GAAATTTTGG CTGTGGATCT ACCCAAAGAA ACAATCTTAC AGTTTTTATC ATTAGAGTGG 4800

GATGCTGATG AACAGGCATT TAACACAACT GTGAAGCAGC TGCTGTCACG CCTGCCAAAG 4860

CAGAGATACC TCAAATTAGT CTGTGATGAA ATTTATAACA TCAAAGTGGA AAAAAAGGTA 4920

TCTGTATTAT TCCTGTATAG CTACAGAGAC GACTACTACC GAATCTTATT TTAA 4974

Domain Profile

S: 1     feeikvlGkGgfgvVlkaknkldkkeyaikriklnkakkelekverevkaLaklehpniv  60

         fee+++lGkG+fg+V+k++nkld+++ya+kri++n a++++++++ ev++L++l+h+niv

Q: 590   FEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIV  649

         89**********************************************************

S: 61    rYfaawleekeesl..............................................  74

         rY++aw+e+ e+++

Q: 650   RYYNAWIERYERPVgsamlppdsdsdsrpqtwdapapsqqpvccggpngpgsveaaappp  709

         ************************************************************

S: 75    ........................................................tdss  78

                                                                 +ds+

Q: 710   ilssvewstsgersasarfqpagpgsssdeeddddedddedehegmfrqpflpasdSDSD  769

         **********99999999999999999999999999999999999998888888753355

S: 79    eveaeaeleesesseesdtk................llyiqmelceketLkdwiderkll  122

          +++++++++++++e+ + k                +lyiqme+cek+tL+d+id+  l+

Q: 770   IIFEDENSKSQNQNEDCNGKnschesepsavveavhYLYIQMEYCEKSTLRDTIDQG-LY  828

         555555555555555555557888888889999999*********************.9*

S: 123   esrselvmrlfkqllegleylHskgliHrdLkpsniFldsddqvKigDFgLatalaealk  182

          ++ +l+ rlf+++l+gl+y+H+kg+iHrdLkp+niFldsdd+vKigDFgLat+ + a++

Q: 829   LDTVRLW-RLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATD-HLAFT  886

         *******.*********************************************9.77778

S: 183   edvkqdaqske.......akhtgqvgtklymsPeql..eksqYnkkvDifsLGlilfeLl  233

         +d kqd+++ +       ++ tg+vgt+ly+sPe +  ++ +Yn+kvD+fsLG+i+fe++

Q: 887   ADGKQDDTADHsiksdpsGHLTGMVGTALYVSPEIQgsSRPTYNQKVDLFSLGIIFFEMS  946

         8888877777667777777****************9888889******************

S: 234   y.pfstemervetltelrd...gkipedfdd.kvpkekkllqkllsrdpkeRpsasellk  288

         y p+ t++er+ +l++lrd    k+pedfdd +++k+k+++++ll++dp++Rp+a+ellk

Q: 947   YhPMVTASERIFVLNQLRDptsPKFPEDFDDgEHTKQKSVISWLLNHDPAKRPTATELLK  1006

         *******************9999*************************************

S: 289   sell  292

         sell

Q: 1007  SELL  1010

         *986

Domain Sequence
(FASTA)

FEELQLLGKG AFGAVIKVQN KLDGCCYAVK RIPINPASRH FRRIKGEVTL LSRLHHENIV 60

RYYNAWIERY ERPVGSAMLP PDSDSDSRPQ TWDAPAPSQQ PVCCGGPNGP GSVEAAAPPP 120

ILSSVEWSTS GERSASARFQ PAGPGSSSDE EDDDDEDDDE DEHEGMFRQP FLPASDSDSD 180

IIFEDENSKS QNQNEDCNGK NSCHESEPSA VVEAVHYLYI QMEYCEKSTL RDTIDQGLYL 240

DTVRLWRLFR EILDGLAYIH EKGMIHRDLK PVNIFLDSDD HVKIGDFGLA TDHLAFTADG 300

KQDDTADHSI KSDPSGHLTG MVGTALYVSP EIQGSSRPTY NQKVDLFSLG IIFFEMSYHP 360

MVTASERIFV LNQLRDPTSP KFPEDFDDGE HTKQKSVISW LLNHDPAKRP TATELLKSEL 420

L 421

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>