EKS-MUP-00200

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00200

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	515.4	3.6E-155	4	284	281

Status

Unreviewed

Ensembl Protein

ENSMPUP00000008825

UniProt Accession

G9K546;

Protein Name

Protein Synonyms/Alias

Intestinal cell kinase;

Gene Name

ICK

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000008895	ENSMPUP00000008825	ENSMPUT00000008969

Organism

Mustela putorius furo

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

MNRYTTIKQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFIFE YMKENLYQLI KERNKLFPES AIRNIMYQIL QGLAFIHKHG 120

FFHRDLKPEN LLCMGPELVK IADFGLAREI RSRPPYTDYV STRWYRAPEV LLRSTSYSSP 180

IDIWAVGCIM AEVYTLRPLF PGASEIDTIF KICQLLGTPK KTDWPEGYQL SSAMNFRWPQ 240

CVPNNLKTLI PNASSEAIQL LRDMLQWDPK KRPTASQALR YPYFQIGHPL GSNTQSLQDS 300

GKAQKDVLEK TGAAPHIKPV PPAQPPTKPH PRISSRQHQA SQPPQHLTYP YKAEASRTDH 360

PNHLPEDKPS PLLFPSLHTK NAQSKMLVGL EHKNGEIKPK SRRRWGLVSR ATKDCDDWAD 420

LDDLDFSPSL PRTDLKNKKR QSEEALCRFE SVLDLKPSEP ISTGSSAPTQ TSYQRRDTPT 480

LRSAAKQHYL KHSRYLPGIN IRNGILPNPG KDFVPSNPWS SSGLSGKSSG TVSVISKINS 540

VGSGSTSSSG LTGNYIPSFL KKEVGSAVQR VHLAPIPDPS PGYSSLKAVR PHPGRPFFHT 600

QPRSTPGLIP RPPAAQPVHG RTDWVSKYAS RR 632

Nucleotide Sequence
(FASTA)

ATGAATAGAT ACACAACGAT CAAGCAACTT GGGGATGGAA CCTACGGTTC CGTCCTACTG 60

GGACGAAGCA TTGAGTCTGG GGAACTGATT GCCATTAAAA AAATGAAAAG AAAGTTTTAT 120

TCCTGGGAGG AATGCATGAA CCTTCGGGAG GTTAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTAA AATTAAAAGA AGTTATCAGG GAAAATGATC ATCTTTATTT TATCTTCGAG 240

TACATGAAGG AAAATCTTTA CCAGCTCATT AAGGAAAGAA ATAAGTTGTT TCCTGAATCT 300

GCCATAAGGA ATATCATGTA CCAGATATTG CAAGGACTCG CATTTATTCA CAAACACGGT 360

TTCTTCCATC GGGACTTAAA GCCTGAGAAC CTCCTCTGCA TGGGCCCGGA ACTTGTGAAA 420

ATTGCAGACT TCGGGTTGGC CCGAGAAATC CGATCCAGAC CCCCATACAC AGACTATGTA 480

TCTACCAGAT GGTACCGGGC TCCGGAAGTG CTCCTGAGGT CTACCAGCTA CAGCTCCCCC 540

ATTGACATCT GGGCCGTGGG CTGCATCATG GCGGAAGTGT ACACCCTCAG GCCACTCTTC 600

CCCGGGGCCA GTGAAATTGA CACCATCTTC AAAATCTGCC AGCTGCTGGG GACACCGAAA 660

AAGACCGACT GGCCTGAAGG CTACCAACTT TCAAGTGCAA TGAACTTCCG CTGGCCCCAG 720

TGTGTACCCA ATAACTTAAA GACCCTGATT CCAAATGCTA GCAGTGAAGC CATTCAGCTC 780

CTGAGAGACA TGCTCCAGTG GGATCCCAAG AAACGGCCAA CAGCTAGTCA GGCGCTTCGA 840

TATCCCTACT TCCAGATTGG GCATCCACTG GGCAGCAACA CACAGAGCCT TCAAGATTCA 900

GGAAAAGCAC AGAAGGATGT CCTGGAAAAG ACAGGCGCAG CTCCTCACAT CAAGCCGGTC 960

CCTCCCGCCC AGCCCCCAAC CAAGCCACAC CCACGGATTT CCTCGAGGCA GCATCAAGCC 1020

AGCCAGCCCC CTCAGCATCT CACGTACCCC TACAAAGCAG AGGCGTCCAG GACAGATCAC 1080

CCGAACCATC TTCCAGAGGA CAAGCCAAGC CCGTTGCTCT TCCCATCCCT CCATACCAAG 1140

AATGCTCAGT CGAAAATGCT AGTTGGCCTG GAACACAAAA ACGGGGAGAT CAAGCCCAAG 1200

AGTCGGAGAA GGTGGGGTCT TGTATCCCGG GCGACAAAGG ATTGTGACGA CTGGGCTGAC 1260

TTGGATGACT TGGATTTCAG TCCGTCCCTC CCCAGGACTG ACCTGAAAAA CAAGAAGAGA 1320

CAGAGCGAGG AGGCTCTCTG CAGATTTGAG AGCGTTCTGG ACCTGAAGCC CTCCGAGCCC 1380

ATCAGTACAG GCAGCAGCGC CCCTACCCAG ACCTCCTATC AGAGGCGAGA CACACCAACC 1440

CTGAGATCCG CGGCCAAGCA GCACTACCTG AAGCACTCGC GATACTTGCC TGGAATAAAT 1500

ATAAGAAACG GCATACTTCC AAATCCAGGC AAGGATTTTG TTCCATCTAA TCCGTGGTCG 1560

AGTTCTGGTT TGTCCGGAAA ATCTTCAGGA ACAGTATCCG TAATCAGCAA AATAAATTCA 1620

GTTGGTTCCG GTTCTACGAG TTCTAGTGGA CTGACTGGAA ACTATATCCC GTCCTTCCTG 1680

AAAAAAGAAG TTGGTTCTGC TGTGCAGAGG GTACACTTGG CTCCTATTCC AGACCCTTCT 1740

CCGGGCTATT CTTCCCTGAA GGCCGTGAGA CCTCATCCTG GGCGACCTTT CTTCCACACC 1800

CAGCCTAGAA GCACTCCCGG GCTGATACCA CGGCCTCCGG CTGCACAGCC CGTGCACGGC 1860

CGGACCGACT GGGTTTCCAA GTACGCGTCT CGGCGATGA 1899

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++ik+lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+++e+m+enlyqlik+r+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDHLYFIFEYMKENLYQLIKERNKLFPESAIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTSYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavGc++aev++lrplfPGaseid+ifki+++lGtPkk++w+e+y+l+sa+n+++pq

Q: 181   IDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQLLGTPKKTDWPEGYQLSSAMNFRWPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++ll+d+l++dP++r+ta+qal+ypyf

Q: 241   CVPNNLKTLIPNASSEAIQLLRDMLQWDPKKRPTASQALRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTIKQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFIFEYMK ENLYQLIKER NKLFPESAIR NIMYQILQGL AFIHKHGFFH 120

RDLKPENLLC MGPELVKIAD FGLAREIRSR PPYTDYVSTR WYRAPEVLLR STSYSSPIDI 180

WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC QLLGTPKKTD WPEGYQLSSA MNFRWPQCVP 240

NNLKTLIPNA SSEAIQLLRD MLQWDPKKRP TASQALRYPY F 281

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0043231	; C:intracellular membrane-bounded organelle
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

Pfam

SMARTs

Prosites

Prints

Created Date

20-Feb-2013