EKS-MUP-00400

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00400

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/IRAK	408.0	2.0E-122	187	493	307

Status

Unreviewed

Ensembl Protein

ENSMPUP00000008986

Gene Name

Irak1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000009059	ENSMPUP00000008986	ENSMPUT00000009134

Organism

Mustela putorius furo

Protein Length

696

Protein Sequence
(FASTA)

MCRFYKVMDA LEPADWCQFA ALIVRDQTEL RLCERSGQRT ASVLWPWINR NARVADLVSI 60

LTHLQLLRAR DIITAWHPPA PLLPPSTSTP RPSSPPAPCE AKVPRPRKLS TSAATVPSPA 120

FPDSQTHSGA ELGPVPSPAS RQQPPPPYPA PSSTKPNPES PVSPLQGAQA SPFCWPLSEI 180

SQGTHNFSEE LKIGEGGFGC VYRAVMRNTP YAVKRLKEGA DLPWVAVKQS FLTEVEQLSR 240

FRHPNIVDFA GYCAQSGFYC LVYGFLPNGS LEDRLHFQTQ ACPPLSWPQR LDILLGTARA 300

IQFLHQDSPS LIHGDIKSSN VLLDERLMPK LGDFGLARLS RFAGASPGQS STVARTQTVR 360

GTLAYLPEDY VKTGRLAVDT DTFSFGVVVL ETLAGQRAVR THGARTKYLK DLVEEEAEEA 420

GVTLKSTRTT VQAGLATDAW ATPIAVQICK KHLDPRPGPC PPELGLALGH LACCCLHRRA 480

KRRPPMTQVY ESLEKLQAVV AGPVPEPDSA GRSPSSPQEN SYISQPSSAP CGASPPEPRA 540

LPSGAPAQAP EWLQKGPNQP VESDESVSGL SAALHSWRLT PSCPPDPAWP GSAGQEATAW 600

APTPLGKASW TQESSWGSGP GLQLTAMEGS LLSSSVASQP PQIIINPARQ KMVRKLALYE 660

DGVLDSLQLL SSGSLRGSGV GPQGRPGPEE SDEFQS 696

Nucleotide Sequence
(FASTA)

ATGTGCCGCT TCTACAAAGT GATGGACGCC CTGGAGCCCG CCGACTGGTG CCAGTTCGCC 60

GCCCTGATCG TGCGCGACCA GACGGAGCTG CGGCTGTGTG AGCGCTCCGG ACAGCGCACG 120

GCCAGCGTCC TTTGGCCCTG GATCAACCGC AACGCCCGCG TGGCCGACCT CGTGAGCATC 180

CTCACGCACC TGCAGTTGCT CCGCGCTCGG GATATCATCA CGGCCTGGCA CCCTCCTGCC 240

CCTCTCCTGC CCCCCAGCAC CAGCACCCCG AGGCCTAGCA GCCCCCCTGC ACCCTGTGAG 300

GCCAAGGTCC CCCGCCCCCG GAAGTTGTCG ACGTCAGCCG CCACAGTCCC CTCCCCAGCT 360

TTTCCAGACT CCCAGACCCA TTCTGGGGCT GAGCTCGGTC CTGTCCCAAG CCCTGCCTCC 420

CGCCAGCAAC CACCACCACC ATACCCAGCC CCTTCCTCCA CCAAGCCTAA CCCGGAGAGC 480

CCAGTGTCCC CCCTGCAGGG AGCCCAGGCC TCTCCCTTTT GCTGGCCCCT CAGTGAGATC 540

TCCCAGGGCA CCCACAACTT CTCAGAGGAG CTGAAGATCG GAGAGGGTGG CTTCGGGTGT 600

GTGTACCGGG CGGTGATGAG GAACACGCCG TACGCAGTGA AGAGGCTAAA GGAGGGGGCG 660

GACCTGCCGT GGGTCGCAGT GAAGCAGAGC TTCCTGACGG AAGTGGAGCA GCTGTCCCGG 720

TTCCGTCACC CCAACATCGT GGACTTTGCT GGTTACTGTG CTCAGAGCGG CTTCTACTGC 780

CTCGTCTATG GCTTCTTGCC CAACGGCTCC CTGGAAGACC GCCTCCACTT CCAGACCCAG 840

GCCTGCCCCC CACTCTCCTG GCCTCAGCGA CTGGACATCC TTTTGGGCAC AGCACGCGCC 900

ATTCAGTTCT TACATCAGGA CAGCCCCAGT CTCATCCACG GGGACATCAA GAGTTCCAAC 960

GTCCTCCTGG ATGAGAGACT GATGCCCAAG CTGGGAGACT TCGGCCTGGC CCGCCTCAGC 1020

CGCTTTGCGG GGGCCAGTCC CGGCCAGAGC AGCACAGTGG CCCGGACGCA GACCGTGCGT 1080

GGCACCCTGG CTTACCTTCC CGAGGACTAT GTCAAGACGG GGAGGCTGGC CGTGGACACG 1140

GATACCTTCA GCTTTGGCGT GGTAGTGCTG GAGACCCTGG CTGGCCAGAG GGCCGTGAGG 1200

ACGCATGGTG CCCGGACCAA GTACCTGAAG GACCTCGTTG AAGAAGAGGC TGAGGAGGCC 1260

GGGGTGACTC TGAAAAGCAC CCGGACCACA GTGCAAGCGG GTCTGGCCAC AGATGCATGG 1320

GCTACCCCCA TTGCCGTCCA GATCTGTAAG AAGCACCTGG ACCCCAGGCC TGGCCCATGC 1380

CCGCCCGAGC TGGGGCTGGC CCTGGGCCAC CTGGCTTGCT GCTGCCTGCA CCGCCGGGCC 1440

AAGAGGAGAC CCCCCATGAC CCAGGTGTAT GAGAGTCTAG AGAAGCTGCA GGCGGTCGTG 1500

GCAGGACCTG TCCCGGAGCC CGATTCTGCT GGCCGCAGCC CCTCTTCCCC GCAGGAGAAC 1560

TCCTACATTT CCCAGCCCAG CAGTGCCCCG TGTGGTGCCA GCCCCCCGGA GCCCCGGGCG 1620

CTCCCCTCGG GAGCACCAGC CCAGGCCCCA GAGTGGCTCC AGAAGGGCCC CAACCAGCCC 1680

GTGGAGAGTG ATGAGAGTGT GTCCGGCCTG TCTGCCGCCT TGCATTCCTG GCGCCTGACC 1740

CCGAGCTGCC CCCCAGACCC GGCCTGGCCA GGCAGCGCAG GGCAAGAGGC CACCGCGTGG 1800

GCCCCGACAC CCCTGGGGAA GGCCAGCTGG ACCCAGGAGT CGAGCTGGGG GAGTGGCCCG 1860

GGGCTGCAGC TGACAGCTAT GGAAGGATCG CTCCTGAGCA GCTCGGTGGC CTCGCAGCCG 1920

CCGCAGATCA TCATCAACCC GGCCCGACAG AAGATGGTGC GGAAGCTGGC CTTGTACGAG 1980

GACGGGGTCT TGGACAGCCT GCAGCTGCTG TCATCCGGCT CCCTCCGAGG CTCAGGTGTG 2040

GGACCCCAAG GCAGGCCTGG GCCCGAGGAG AGTGACGAGT TTCAGAGCTG A 2091

Domain Profile

S: 1     fsednrigeGgfgevyrgelkntavavkklkeeadlslkelkqsfltElkvlarfrHdni  60

         fse+ +igeGgfg+vyr+ ++nt +avk+lke adl + ++kqsfltE+++l+rfrH+ni

Q: 187   FSEELKIGEGGFGCVYRAVMRNTPYAVKRLKEGADLPWVAVKQSFLTEVEQLSRFRHPNI  246

         899*********************************************************

S: 61    lellgysaeseklcLvYqymknGsLedrLqcq.kgsepLsWpqRlsillGtaraiefLHe  119

         ++++gy+a+s+++cLvY++++nGsLedrL+ q ++++pLsWpqRl+illGtarai+fLH+

Q: 247   VDFAGYCAQSGFYCLVYGFLPNGSLEDRLHFQtQACPPLSWPQRLDILLGTARAIQFLHQ  306

         *******************************99***************************

S: 120   aspslihgdiksaNiLLDekltpKlgDfglar...fapesekqsstvlrtskvrgtlaYl  176

         +spslihgdiks+N+LLDe+l+pKlgDfglar   fa++s+ qsstv+rt++vrgtlaYl

Q: 307   DSPSLIHGDIKSSNVLLDERLMPKLGDFGLARlsrFAGASPGQSSTVARTQTVRGTLAYL  366

         *******************************99999************************

S: 177   peefirvgqltvkvDvySfGiVllEvltGlra.vdedrktkyLkdllkeeieeekv....  231

         pe+++++g+l+v++D++SfG+V+lE+l+G+ra ++++++tkyLkdl++ee+ee++v

Q: 367   PEDYVKTGRLAVDTDTFSFGVVVLETLAGQRAvRTHGARTKYLKDLVEEEAEEAGVtlks  426

         ********************************77899***********************

S: 232   ....................eilekfldkkagkleeellealielalaclaekakkrPtm  271

                             +i++k+ld ++g++++el  al +la++cl+++ak+rP+m

Q: 427   trttvqaglatdawatpiavQICKKHLDPRPGPCPPELGLALGHLACCCLHRRAKRRPPM  486

         ************************************************************

S: 272   sqvlell  278

         +qv+e+l

Q: 487   TQVYESL  493

         ****987

Domain Sequence
(FASTA)

FSEELKIGEG GFGCVYRAVM RNTPYAVKRL KEGADLPWVA VKQSFLTEVE QLSRFRHPNI 60

VDFAGYCAQS GFYCLVYGFL PNGSLEDRLH FQTQACPPLS WPQRLDILLG TARAIQFLHQ 120

DSPSLIHGDI KSSNVLLDER LMPKLGDFGL ARLSRFAGAS PGQSSTVART QTVRGTLAYL 180

PEDYVKTGRL AVDTDTFSFG VVVLETLAGQ RAVRTHGART KYLKDLVEEE AEEAGVTLKS 240

TRTTVQAGLA TDAWATPIAV QICKKHLDPR PGPCPPELGL ALGHLACCCL HRRAKRRPPM 300

TQVYESL 307

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>