EKS-MUP-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	527.4	7.0E-159	24	291	268

Status

Unreviewed

Ensembl Protein

ENSMPUP00000012044

UniProt Accession

G9KGE1;

Protein Name

Protein Synonyms/Alias

Phosphorylase kinase, gamma 2;

Gene Name

PHKG2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000012139	ENSMPUP00000012044	ENSMPUT00000012242

Organism

Mustela putorius furo

Functional Description

Protein Length

406

Protein Sequence
(FASTA)

MTLDVGPEDE LPDWAAAKEF YQKYDPKDVI GRGVSSVVRR CVHRATGHEF AVKIMEVTAE 60

RLSPEQLEEV REATRRETHI LRQVAGHPHI ITLIDSYESS SFMFLVFDLM RKGELFDYLT 120

EKVALSEKET RSIMRSLLEA VSFLHANNIV HRDLKPENIL LDDNMQIRLS DFGFSCHLEP 180

GEKLRELCGT PGYLAPEILK CSMDETHPGY GKEVDLWACG VILFTLLAGS PPFWHRRQIL 240

MLRMIMEGQY QFSSPEWDDR SNTVKDLISK LLQVDPEERL TADQALQHPF FERCEGSQPW 300

NLTPRQRFRV AVWTVLAAGR VALSTQRVRP LTKSALLRDP YALRPVRRLI DSCAFRLYGH 360

WVKKGEQQNR AALFQHQPPG PFPVLGPEEE GDSTAIPEED ALLALG 406

Nucleotide Sequence
(FASTA)

ATGACGCTGG ACGTGGGCCC GGAGGATGAG CTGCCCGACT GGGCCGCGGC CAAGGAGTTT 60

TACCAGAAGT ACGACCCTAA GGACGTCATT GGCAGAGGAG TGAGCTCCGT GGTGCGCCGT 120

TGTGTTCATC GAGCCACTGG CCACGAGTTT GCGGTGAAGA TCATGGAGGT GACAGCCGAG 180

CGGCTGAGTC CTGAACAGCT AGAGGAGGTG CGAGAAGCCA CGCGGCGAGA GACGCACATC 240

CTTCGCCAGG TCGCCGGCCA CCCCCACATC ATCACTCTCA TCGATTCCTA CGAGTCTTCT 300

AGCTTCATGT TCCTGGTGTT TGACCTGATG CGGAAGGGAG AGCTGTTTGA CTATCTCACA 360

GAGAAGGTGG CCCTCTCCGA AAAGGAAACC AGGTCCATCA TGAGGTCTCT GCTGGAAGCA 420

GTGAGCTTTC TCCACGCCAA CAACATTGTG CATCGAGACC TGAAGCCCGA GAATATTCTC 480

CTGGATGACA ATATGCAGAT CCGACTTTCA GATTTTGGGT TCTCCTGCCA CTTGGAACCT 540

GGCGAGAAGC TCCGAGAGTT GTGTGGGACC CCAGGGTACC TCGCACCAGA GATCCTTAAA 600

TGCTCCATGG ACGAGACCCA CCCCGGCTAC GGCAAGGAGG TCGACCTCTG GGCCTGCGGC 660

GTGATCTTGT TCACACTCCT GGCCGGCTCA CCACCATTCT GGCACCGCCG CCAGATCCTG 720

ATGTTACGCA TGATCATGGA AGGCCAGTAC CAGTTCAGCT CGCCCGAGTG GGATGACCGT 780

TCCAACACGG TCAAAGACCT GATCTCCAAG CTGCTCCAGG TGGACCCTGA GGAGCGCCTG 840

ACAGCGGACC AGGCCCTGCA GCACCCGTTC TTTGAGCGCT GTGAAGGCAG CCAGCCCTGG 900

AACCTCACGC CCCGCCAGCG GTTCCGGGTG GCAGTGTGGA CCGTGCTTGC TGCGGGACGT 960

GTGGCCTTAA GCACCCAGCG TGTGCGGCCA CTGACCAAGA GCGCACTGCT GAGGGACCCT 1020

TACGCGCTGC GGCCCGTGCG GCGCCTCATC GACAGCTGTG CCTTCCGGCT CTATGGGCAC 1080

TGGGTGAAGA AGGGGGAGCA ACAGAACCGC GCCGCGCTCT TCCAGCACCA GCCCCCCGGG 1140

CCTTTTCCCG TCCTGGGCCC TGAAGAGGAG GGGGACTCCA CTGCTATCCC GGAGGAGGAT 1200

GCGCTGCTGG CGCTGGGCTA G 1221

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         y+pk+++GrGvssvvrrc+++atg+efavki++v+ae+ls+e+++e+reat++e++ilrq

Q: 24    YDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQ  83

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         v+Ghp+ii+l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++

Q: 84    VAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSF  143

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lha+nivhrdlkpenillddn++i+lsdfGfs++le+GeklrelcGtpgylapeilkcsm

Q: 144   LHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSM  203

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         de++pGy+kevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++

Q: 204   DETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSNT  263

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdliskll+vdpe+rlta++al+hpff

Q: 264   VKDLISKLLQVDPEERLTADQALQHPFF  291

         ***************************8

Domain Sequence
(FASTA)

YDPKDVIGRG VSSVVRRCVH RATGHEFAVK IMEVTAERLS PEQLEEVREA TRRETHILRQ 60

VAGHPHIITL IDSYESSSFM FLVFDLMRKG ELFDYLTEKV ALSEKETRSI MRSLLEAVSF 120

LHANNIVHRD LKPENILLDD NMQIRLSDFG FSCHLEPGEK LRELCGTPGY LAPEILKCSM 180

DETHPGYGKE VDLWACGVIL FTLLAGSPPF WHRRQILMLR MIMEGQYQFS SPEWDDRSNT 240

VKDLISKLLQ VDPEERLTAD QALQHPFF 268

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013