EKS-MUP-00258

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00258

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	426.2	4.3E-128	53	305	253

Status

Unreviewed

Ensembl Protein

ENSMPUP00000012091

Gene Name

PLK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000012187	ENSMPUP00000012091	ENSMPUT00000012290

Organism

Mustela putorius furo

Protein Length

542

Protein Sequence
(FASTA)

MSAAATAGKL ARAPADPGKA GGPGGAAPGA PAAAPPAKEI PEVLVDPRSR RRYLRGRFLG 60

KGGFAKCFEI SDADTKEVFA GKIVPKSLLL KPHQKEKMSM EISIHRSLAH QHIVGFHGFF 120

EDNDFVFVVL ELCRRRSLLE LHKRRKALTE PEARYYLRQI VLGCQYLHRN RVIHRDLKLG 180

NLFLNEDLEV KIGDFGLATK VEYDGERKKT LCGTPNYIAP EVLSKKGHSF EVDVWSIGCI 240

MYTLLVGKPP FETSCLKETY LRIKKNDYSI PKHVNPVAAS LIQKMLQTDP TARPTIHELL 300

NDEFFTSGYI PARLPITCLT IAPRFSIAPS SLDPNSRKPL TVLNKGTENP MPERPREKEE 360

PGVRETNEVV DCHLGDMLQQ LHSVNASKPS ERGLVRQEEA EDPACIPIFW VSKWVDYSDK 420

YGLGYQLCDN SVGVLFNDST RLILYNDGDS LQYIERDGTE SYLTVSSHPN SLMKKITLLK 480

YFRNYMSEHL LKAGANITPR EGDELARLPY LRTWFRTRSA IILHLSNGCV QINFFQDPGI 540

IT 542

Nucleotide Sequence
(FASTA)

ATGAGTGCGG CGGCAACTGC AGGGAAGCTG GCGCGGGCAC CAGCGGACCC AGGGAAAGCC 60

GGGGGTCCCG GAGGTGCAGC TCCCGGGGCC CCGGCTGCTG CTCCGCCGGC GAAAGAGATC 120

CCGGAGGTCC TAGTGGACCC GCGCAGCCGG CGGCGCTACC TGCGGGGACG CTTTCTGGGG 180

AAGGGAGGCT TTGCTAAGTG CTTCGAAATC TCGGACGCTG ACACTAAGGA GGTGTTCGCG 240

GGCAAGATCG TGCCTAAGTC TCTGCTGCTC AAGCCGCACC AGAAGGAGAA GATGTCCATG 300

GAGATATCCA TTCACCGCAG CCTCGCCCAC CAGCACATCG TAGGCTTCCA CGGCTTTTTC 360

GAAGACAATG ACTTCGTATT CGTGGTGTTG GAGCTCTGCC GCCGGAGGTC TCTCCTGGAG 420

CTGCACAAAC GGAGGAAAGC ACTGACCGAG CCGGAAGCCC GCTACTACCT TCGGCAGATT 480

GTCCTTGGCT GCCAGTACCT GCACCGAAAC CGGGTTATTC ACCGGGACCT CAAGCTGGGC 540

AACCTTTTCC TGAATGAGGA TCTGGAGGTG AAAATAGGGG ATTTTGGACT GGCAACCAAA 600

GTGGAATATG ACGGGGAACG CAAGAAGACC TTGTGCGGGA CTCCCAATTA CATAGCTCCT 660

GAGGTGCTGA GCAAGAAAGG GCACAGTTTC GAGGTGGACG TGTGGTCCAT TGGGTGTATC 720

ATGTATACAT TGTTAGTGGG CAAACCACCT TTTGAGACCT CTTGCCTCAA AGAGACCTAC 780

CTCCGGATCA AGAAGAATGA CTACAGTATT CCCAAGCATG TCAACCCTGT GGCCGCCTCC 840

CTCATCCAGA AGATGCTTCA GACAGATCCT ACTGCCCGCC CCACCATTCA TGAGCTGCTC 900

AATGACGAGT TCTTTACTTC CGGCTACATC CCTGCCCGAC TCCCCATCAC CTGTCTCACA 960

ATTGCACCCC GGTTTTCTAT TGCTCCCAGC AGTTTGGACC CCAACAGCCG GAAACCTCTT 1020

ACAGTCCTCA ATAAAGGCAC GGAGAACCCC ATGCCTGAGC GGCCCCGGGA AAAAGAGGAG 1080

CCAGGAGTCC GGGAGACCAA TGAAGTGGTT GACTGCCACC TGGGCGATAT GCTACAGCAG 1140

CTACACAGCG TCAATGCATC CAAGCCCTCA GAGCGGGGGC TGGTGAGGCA AGAGGAGGCT 1200

GAGGATCCTG CCTGCATCCC CATCTTCTGG GTCAGCAAGT GGGTGGACTA TTCGGACAAG 1260

TACGGCCTCG GGTACCAGCT ATGTGACAAC AGCGTGGGGG TGCTCTTCAA TGACTCGACA 1320

CGCCTGATCC TCTACAATGA CGGTGACAGC CTGCAGTACA TAGAGCGCGA TGGCACTGAG 1380

TCCTACCTCA CCGTGAGCTC ACATCCCAAC TCCCTGATGA AGAAGATCAC CCTCCTGAAG 1440

TATTTCCGGA ACTACATGAG TGAACACTTG CTGAAGGCGG GGGCCAACAT CACGCCCCGG 1500

GAAGGCGATG AGCTCGCCCG GCTACCCTAC CTGCGCACCT GGTTTCGCAC CCGCAGTGCC 1560

ATCATCCTGC ACCTCAGCAA TGGCTGTGTG CAGATCAACT TCTTCCAGGA CCCTGGGATC 1620

ATAACCTGA 1629

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         y rg++lGkGgfakc+e++d++tkevfa k+vpksll k++q+ek+++ei+ihrsl+h++

Q: 53    YLRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQKEKMSMEISIHRSLAHQH  112

         889*********************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrrkaltepevryylrqivsglkylhekri  120

         iv ++ ffed+++v++vlelc+rrsl el+krrkaltepe+ryylrqiv g++ylh++r+

Q: 113   IVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRV  172

         ************************************************************

S: 121   lhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghslev  180

         +hrdlklgnlflne+levkigdfGlat++e+++erkktlcGtPnyiaPevlskkghs+ev

Q: 173   IHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEV  232

         ************************************************************

S: 181   diWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePee  240

         d+Ws+Gci+ytllvGkPPfet++lkety +ikk++ys+P+++++ a+sli+k+l+++P++

Q: 233   DVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNDYSIPKHVNPVAASLIQKMLQTDPTA  292

         ************************************************************

S: 241   rpsleevlkdefl  253

         rp+++e+l+def+

Q: 293   RPTIHELLNDEFF  305

         ************8

Domain Sequence
(FASTA)

YLRGRFLGKG GFAKCFEISD ADTKEVFAGK IVPKSLLLKP HQKEKMSMEI SIHRSLAHQH 60

IVGFHGFFED NDFVFVVLEL CRRRSLLELH KRRKALTEPE ARYYLRQIVL GCQYLHRNRV 120

IHRDLKLGNL FLNEDLEVKI GDFGLATKVE YDGERKKTLC GTPNYIAPEV LSKKGHSFEV 180

DVWSIGCIMY TLLVGKPPFE TSCLKETYLR IKKNDYSIPK HVNPVAASLI QKMLQTDPTA 240

RPTIHELLND EFF 253

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>