EKS-MUP-00207

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00207

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/MAST	218.6	1.0E-64	1	201	201

Status

Unreviewed

Ensembl Protein

ENSMPUP00000012172

UniProt Accession

G9K9R0;

Protein Name

Protein Synonyms/Alias

Microtubule associated serine/threonine kinase-like protein;

Gene Name

MASTL

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000012269	ENSMPUP00000012172	ENSMPUT00000012372

Organism

Mustela putorius furo

Functional Description

Protein Length

787

Protein Sequence
(FASTA)

MEYLIGGDVK SLLHIYGYFD EEMAVKYISE VALALDYLHR HGIIHRDLKP DNMLISNEGH 60

IKLTDFGLSK VTLNRDINMM DILTTPSMAK PRQDYSRTPG QVLSLISSLG FYTPVAEKNK 120

DSANILSPHV SETSQLSQGL VCPMSVDHRD ATPYSSKLLN SCLETVASNP GMPVKCLTSN 180

LLQSRRRLAT SSTSSQSHTF VSSVESESHS SPRWEKDCQE SDNAPGSTVM SWNIIEKPSC 240

TKSTNAIETQ GFNKKDLELA LSPIHNSSTI SETGSSCVNL AKKCLPKEVS WQARELDINN 300

IHVATDPAHS GFHQSDQWAV DPGDRTAEHL EKRSFKRTFE LVDSSPCQTI IQNKKNCIEH 360

KSRNEMNDGY INQRTGITME VQDLKLSECG GQQGDCADKE NMVNSFTDKP QTPEKSPIPM 420

IAKNLLCELD EDCDKNNKKD LLSSSFLCSD DERASKSMCM DSDSSFPGIS IMESSLERQS 480

LDPDKSIKES SFEESNIEDL LTVSPSWQEN TLPKGDENLV VQDSSQKMLA PSSEVLKTLT 540

LSKRNAVAFR SFNSHINASN NSEPSKMSIT SLDAMDISCV YSGSYPMAIT PNQKGASYKP 600

YQQTPKQVKS GTPYRTPKSV RRGAAPMDDG RILGTPDYLA PELLLARAHG AAVDWWALGV 660

CLFEFLTGIP PFNDETPQQV FQNILKRDIP WPEGEEKLSD NAQNAVEILL TIDNAKRAGM 720

KELRCHPLFS DVDWENLQHQ TMPFIPQPDG KQDTEHAQER YRLCCRSFIC PSRSLGTLLQ 780

PAYVLGS 787

Nucleotide Sequence
(FASTA)

ATGGAATATC TTATTGGTGG TGATGTCAAG TCTCTCCTAC ATATATATGG TTATTTTGAT 60

GAAGAGATGG CCGTGAAATA TATTTCTGAA GTAGCCTTGG CTCTAGACTA CCTTCACAGA 120

CATGGAATCA TCCACAGGGA TTTGAAACCA GACAATATGC TTATTTCTAA TGAAGGTCAT 180

ATTAAATTAA CAGATTTTGG CCTTTCCAAA GTTACTTTGA ATAGAGACAT CAATATGATG 240

GATATCCTTA CAACACCATC AATGGCTAAA CCTAGACAAG ACTACTCAAG AACCCCAGGA 300

CAAGTGTTAT CTCTCATCAG CTCTTTGGGA TTTTACACAC CAGTTGCAGA AAAAAACAAA 360

GACTCTGCAA ATATTCTTTC ACCCCATGTA TCTGAAACAT CGCAGCTTTC TCAAGGACTA 420

GTTTGTCCTA TGTCTGTAGA TCACAGGGAT GCTACTCCTT ACTCTAGCAA ACTACTAAAT 480

TCATGTCTGG AAACAGTTGC CTCCAATCCC GGGATGCCCG TTAAGTGCCT AACGTCTAAT 540

CTCCTGCAGT CCAGGAGAAG GCTGGCTACA TCCAGCACCA GCAGCCAGTC GCATACCTTC 600

GTATCCAGTG TGGAGTCTGA GAGCCACAGC AGTCCCAGAT GGGAGAAGGA CTGCCAGGAA 660

AGTGACAATG CACCGGGCTC TACAGTGATG AGTTGGAATA TAATAGAAAA GCCTTCATGT 720

ACAAAATCAA CCAATGCCAT CGAGACCCAA GGTTTCAATA AAAAGGATCT TGAGTTAGCC 780

CTTTCTCCCA TTCATAACAG CAGTACCATT TCTGAGACTG GAAGCTCTTG TGTAAACCTG 840

GCCAAAAAAT GCCTCCCCAA GGAAGTTTCT TGGCAAGCAA GAGAACTGGA TATAAATAAT 900

ATTCATGTGG CCACTGACCC AGCACACTCT GGTTTTCACC AGTCAGATCA GTGGGCTGTA 960

GATCCTGGTG ATAGGACTGC AGAGCACCTT GAAAAAAGAA GTTTTAAAAG AACTTTTGAG 1020

TTAGTTGACT CTAGTCCTTG TCAGACCATC ATACAGAATA AAAAAAACTG TATAGAGCAT 1080

AAGTCTAGAA ATGAAATGAA CGATGGTTAT ATAAACCAAA GGACAGGCAT AACAATGGAA 1140

GTCCAAGACC TGAAGCTATC AGAGTGCGGA GGTCAGCAAG GTGACTGTGC TGATAAGGAG 1200

AACATGGTCA ATTCTTTCAC TGATAAACCA CAAACCCCAG AAAAATCACC TATCCCAATG 1260

ATAGCAAAAA ACCTTCTATG TGAACTGGAT GAGGATTGTG ACAAGAATAA TAAGAAAGAC 1320

CTCCTAAGTT CGAGTTTTCT ATGTTCCGAT GACGAGAGAG CTTCTAAAAG TATGTGTATG 1380

GACTCCGATT CATCTTTTCC TGGAATTTCT ATCATGGAGA GTTCATTAGA AAGGCAGTCC 1440

TTGGATCCAG ATAAAAGCAT TAAAGAATCC TCTTTTGAAG AATCAAACAT TGAAGACCTA 1500

CTTACCGTAT CACCCAGCTG GCAAGAAAAT ACCTTGCCAA AAGGCGATGA GAATCTTGTT 1560

GTCCAAGATA GTAGCCAAAA AATGTTAGCT CCATCTTCAG AGGTGCTGAA AACATTAACC 1620

TTATCTAAAA GAAATGCTGT AGCTTTTCGA AGTTTTAACA GCCATATCAA TGCATCCAAT 1680

AACTCAGAAC CATCCAAAAT GAGCATTACC TCTTTAGATG CAATGGATAT TTCCTGCGTT 1740

TATAGTGGTT CATATCCCAT GGCTATAACC CCTAATCAAA AAGGAGCATC CTATAAGCCA 1800

TATCAGCAGA CCCCGAAACA GGTCAAATCA GGAACTCCAT ATCGAACTCC GAAGAGTGTG 1860

AGGCGAGGGG CGGCCCCCAT GGATGATGGG CGGATTCTTG GAACACCGGA CTACCTCGCA 1920

CCTGAGCTCT TACTGGCCAG GGCCCATGGT GCTGCAGTAG ACTGGTGGGC ACTTGGAGTT 1980

TGCTTGTTTG AGTTTCTAAC AGGAATTCCT CCTTTCAATG ATGAAACACC ACAACAAGTA 2040

TTCCAGAATA TTCTGAAAAG AGATATCCCT TGGCCTGAAG GTGAAGAAAA GTTATCTGAT 2100

AATGCTCAAA ATGCAGTAGA AATACTTTTA ACTATTGATA ATGCAAAGAG AGCTGGAATG 2160

AAAGAGCTGA GATGTCATCC TCTCTTCAGT GATGTGGACT GGGAAAATCT GCAACATCAA 2220

ACTATGCCTT TCATACCCCA ACCAGATGGT AAACAGGATA CGGAGCATGC CCAGGAGAGG 2280

TACCGACTGT GCTGTAGATC TTTCATTTGC CCCTCCAGAT CCCTTGGCAC CCTTCTCCAG 2340

CCTGCTTATG TCCTGGGAAG CTGA 2364

Domain Profile

S: 78    meyveGGdvksllkniGaldvemarlyiaevvlaleylhryGivhrdlkPdnllitseGh  137

         mey++GGdvksll+++G++d+ema++yi+ev+lal+ylhr+Gi+hrdlkPdn+li++eGh

Q: 1     MEYLIGGDVKSLLHIYGYFDEEMAVKYISEVALALDYLHRHGIIHRDLKPDNMLISNEGH  60

         9***********************************************************

S: 138   ikltdfGlskvglmslttnlyegyidkdarefldkqvcgtPeyiaPevilrqgygkpvdw  197

         ikltdfGlskv+l+          +d++++++l     +tP++++P    rq+y++++++

Q: 61    IKLTDFGLSKVTLN----------RDINMMDIL-----TTPSMAKP----RQDYSRTPGQ  101

         **************..........********9.....********....**********

S: 198   walgiilyeflvgivpffgdtpeelfaqv.....lsdeivwP....ekde.alssealel  247

         ++++i++++f+++++++++d+++ l+ +v     ls+++v+P    ++d  ++ss++l++

Q: 102   VLSLISSLGFYTPVAEKNKDSANILSPHVsetsqLSQGLVCPmsvdHRDAtPYSSKLLNS  161

         **************************99999999********9997555569********

S: 248   isellesnP..............rerlgtgsaaevkqhefl  274

         + e+++snP              r+rl+t s++++++h+f+

Q: 162   CLETVASNPgmpvkcltsnllqsRRRLAT-SSTSSQSHTFV  201

         **********************999***9.9999****996

Domain Sequence
(FASTA)

MEYLIGGDVK SLLHIYGYFD EEMAVKYISE VALALDYLHR HGIIHRDLKP DNMLISNEGH 60

IKLTDFGLSK VTLNRDINMM DILTTPSMAK PRQDYSRTPG QVLSLISSLG FYTPVAEKNK 120

DSANILSPHV SETSQLSQGL VCPMSVDHRD ATPYSSKLLN SCLETVASNP GMPVKCLTSN 180

LLQSRRRLAT SSTSSQSHTF V 201

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0032154	; C:cleavage furrow
GO:0005634	; C:nucleus
GO:0004674	; F:protein serine/threonine kinase activity
GO:0000086	; P:G2/M transition of mitotic cell cycle
GO:0007067	; P:mitosis
GO:0034048	; P:negative regulation of protein phosphatase type 2A activity
GO:0051726	; P:regulation of cell cycle

KEGG

InterPros

Pfam

SMARTs

Prosites

Prints

Created Date

20-Feb-2013