EKS-MUP-00318

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00318

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	322.2	2.4E-96	36	294	259

Status

Unreviewed

Ensembl Protein

ENSMPUP00000012666

UniProt Accession

G9KRL9;

Protein Name

Protein Synonyms/Alias

Serine/threonine kinase 10;

Gene Name

Stk10

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000012761	ENSMPUP00000012666	ENSMPUT00000012870

Organism

Mustela putorius furo

Functional Description

Protein Length

967

Protein Sequence
(FASTA)

MAFANFRRIL RLSTFEKRKS REYEHVRRDV DPNEVWEIVG ELGDGAFGKV YKAKNKETGA 60

LAAAKVIETK SEEELEDYTV EIDILATCDH PYIVKLLGAY YYDGKLWIMI EFCPGGAVDA 120

IMLELDRGLT EPQIQVVCRQ MLEALNFLHG KKIIHRDLKA GNVLMTLEGD IRLADFGVSA 180

KNLKTLQKRD SFIGTPYWMA PEVVMCETMK DTPYDYKADI WSLGITLIEM AQIEPPHHEL 240

NPMRVLLKIA KSDPPTLLSP SKWSVEFRDF LKTALDKNPE TRPSAAQLLE HPFVSSVTSN 300

KALRELVAEA KAEVMEEIED GREEGEEEDS TDATSPLGNH TQDSSEVSQL SLNTDKLLKE 360

PSFTPLPPGQ PQDNVNGPSQ PPGDRSLQTT NPPDAAPGNE NGLAVPAPLR KSRPVSMDAR 420

IQVSEEKQVA DQEVKLSPTA NKSQKSSQSR PNSSALETLG TEKLANGSLE LPTQAAPGPS 480

KRDSDCGSLS TSESMDYSTS LSADLSLNRE TGSLSLKDSR LHNKTLKRTR KFVVDGVEVS 540

ITTSKIISED EKKDEEMRFL RRQELRELRL LQKEEHRNQT QLSSKHELQL EQMQKRFEQE 600

INAKKKFFDT ELENLERQQK QQVEKMEQDH AVRRREEAKR IRLEQDRDYT KFQEQLKLMK 660

KEVKNEVEKL PRQQRKESMK QKMEEHAQKK QLLDRDFLAK QKEDLELAMK KITADNRREI 720

CDKERECLTK KQELLRDREA ALWEMEEHHL QERHQLVKQQ LKDQYFLQRH ELVRKHEKER 780

EQMQRYNQRM VEQLKVRQQQ EKARLPKIQR SEGKTRMAMY KKSLHINGAG SASEQREKIK 840

QFSQQEEKRQ KSERLQQQQK HENQMRDMMA QCESNMSELQ QLQNEKCHLL VEHETQKLKA 900

LDESHNQNLK EWRDKLRPRK KALEEDLNQK KREQEMFFKM NEETECLNPT TPNKATKFFP 960

YSSVDTS 967

Nucleotide Sequence
(FASTA)

ATGGCTTTCG CCAATTTCCG CCGCATCCTG CGCCTGTCTA CATTCGAGAA GAGAAAGTCC 60

CGCGAATATG AGCACGTCCG CCGGGACGTG GACCCCAACG AGGTGTGGGA GATCGTGGGC 120

GAGCTGGGCG ACGGCGCCTT CGGAAAGGTT TACAAGGCCA AGAACAAGGA GACAGGTGCT 180

TTGGCTGCCG CCAAGGTAAT TGAGACCAAG AGTGAGGAGG AGCTGGAGGA CTACACCGTG 240

GAGATCGACA TCCTGGCCAC CTGTGACCAC CCCTACATTG TCAAGCTCCT GGGAGCCTAC 300

TATTACGATG GGAAGCTGTG GATCATGATC GAGTTCTGTC CTGGGGGAGC CGTGGACGCC 360

ATCATGCTGG AGCTAGACAG AGGCCTCACG GAGCCCCAGA TTCAGGTGGT TTGCCGCCAG 420

ATGCTAGAAG CCCTCAACTT TCTGCACGGC AAGAAGATCA TCCACCGGGA CCTGAAAGCT 480

GGCAATGTGC TGATGACCCT CGAGGGAGAT ATCAGGCTGG CTGACTTTGG TGTGTCTGCC 540

AAGAATCTGA AAACTCTGCA GAAGCGAGAT TCCTTCATAG GAACGCCTTA CTGGATGGCC 600

CCTGAGGTGG TGATGTGTGA GACCATGAAG GACACCCCGT ACGACTACAA AGCTGACATC 660

TGGTCCCTGG GAATCACTCT GATTGAGATG GCCCAGATTG AGCCCCCGCA CCATGAGCTC 720

AACCCCATGC GGGTCCTGCT CAAGATTGCC AAGTCGGATC CCCCCACGCT GCTCTCACCT 780

TCCAAGTGGT CTGTGGAGTT CCGCGACTTC CTGAAGACGG CCCTCGATAA GAACCCGGAG 840

ACCCGGCCCA GTGCTGCGCA GCTCCTGGAG CATCCCTTCG TCAGCAGCGT CACCAGCAAC 900

AAGGCTTTGC GGGAGTTGGT GGCCGAGGCC AAGGCTGAAG TGATGGAGGA GATCGAGGAT 960

GGCCGGGAGG AGGGGGAAGA GGAGGACTCC ACGGATGCCA CTTCTCCTCT GGGGAACCAT 1020

ACTCAAGACT CTTCTGAGGT GAGTCAGCTG AGTCTCAATA CCGACAAGCT TCTCAAAGAA 1080

CCATCCTTCA CCCCACTGCC ACCTGGCCAG CCTCAGGACA ATGTGAATGG GCCCAGCCAG 1140

CCCCCTGGGG ACAGATCCCT CCAAACCACC AACCCCCCAG ATGCAGCTCC TGGAAATGAG 1200

AATGGCCTGG CGGTGCCAGC ACCATTACGG AAGTCCCGGC CAGTGTCAAT GGATGCCAGA 1260

ATTCAGGTAT CTGAGGAGAA GCAAGTCGCT GACCAGGAAG TGAAGCTCAG TCCAACAGCT 1320

AACAAGTCCC AAAAATCAAG CCAGAGCCGC CCCAACAGCA GTGCCCTGGA GACCTTGGGT 1380

ACTGAGAAGT TAGCCAACGG CAGCCTGGAG CTCCCCACCC AGGCCGCCCC TGGCCCGTCC 1440

AAGAGGGACT CAGACTGTGG GAGCCTCTCC ACCTCCGAGA GCATGGACTA CAGCACCTCT 1500

CTCTCAGCCG ACCTGTCCCT GAACAGAGAA ACAGGCTCTC TGTCCCTCAA GGACTCAAGG 1560

CTGCACAATA AAACCCTCAA GAGGACACGC AAGTTTGTGG TGGACGGTGT CGAGGTGAGC 1620

ATCACCACCT CCAAGATCAT CAGCGAGGAT GAGAAGAAGG ATGAGGAGAT GCGGTTTCTC 1680

AGGCGCCAGG AGCTCCGTGA GCTTCGGCTG CTCCAGAAAG AAGAGCATCG GAACCAGACC 1740

CAGTTGAGCA GCAAGCACGA GCTGCAGCTG GAGCAGATGC AAAAACGTTT CGAACAAGAG 1800

ATCAATGCCA AGAAGAAGTT CTTCGACACA GAGCTGGAGA ACCTGGAGCG TCAGCAGAAG 1860

CAGCAAGTGG AGAAGATGGA GCAGGACCAC GCGGTGCGCC GCCGGGAGGA GGCCAAGCGG 1920

ATCCGGCTGG AGCAGGACCG GGACTATACT AAGTTCCAGG AGCAGCTCAA ACTGATGAAG 1980

AAGGAGGTGA AGAACGAGGT GGAGAAGCTC CCCAGGCAAC AGCGGAAGGA GAGCATGAAG 2040

CAGAAGATGG AGGAACATGC GCAGAAGAAG CAGCTTCTCG ACCGGGACTT CCTGGCCAAG 2100

CAGAAGGAGG ACTTGGAGCT GGCGATGAAG AAGATCACTG CTGACAACAG GCGGGAGATC 2160

TGTGACAAGG AGCGCGAGTG TCTCACTAAG AAGCAGGAAC TCCTTCGAGA CCGGGAGGCC 2220

GCCCTATGGG AAATGGAGGA GCATCACCTG CAGGAGAGGC ACCAACTGGT GAAGCAGCAG 2280

CTCAAAGACC AGTACTTTCT CCAGCGGCAT GAGCTGGTGC GCAAGCATGA GAAGGAGCGG 2340

GAGCAGATGC AGCGCTACAA TCAGCGCATG GTGGAGCAGC TGAAGGTGCG GCAGCAGCAG 2400

GAGAAAGCGC GGCTGCCCAA GATTCAGAGG AGCGAGGGTA AGACGCGCAT GGCCATGTAC 2460

AAGAAGAGCC TCCACATCAA CGGCGCGGGC AGTGCCTCGG AGCAGCGCGA GAAGATCAAG 2520

CAGTTCTCCC AGCAAGAGGA GAAGAGGCAG AAGTCAGAGC GGCTACAGCA GCAGCAAAAA 2580

CATGAGAACC AGATGCGGGA CATGATGGCA CAGTGTGAGA GCAACATGAG CGAGCTGCAG 2640

CAGCTGCAGA ATGAAAAGTG TCACCTCCTG GTAGAACATG AAACTCAGAA GCTGAAGGCT 2700

CTAGATGAGA GCCATAACCA GAACCTGAAG GAATGGCGGG ACAAGCTTCG GCCACGCAAA 2760

AAGGCACTGG AAGAAGATCT GAACCAGAAG AAGCGAGAAC AGGAGATGTT CTTCAAAATG 2820

AATGAGGAGA CAGAATGCCT GAACCCTACC ACCCCAAATA AGGCCACCAA GTTCTTCCCC 2880

TACAGCTCTG TGGATACTTC TTAA 2904

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkhpnive  60

         +e++ e+g+Ga+gkvy+a++k+tg+l+a k+i+++++e+le+++ ei +l +++hp+iv+

Q: 36    WEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYTVEIDILATCDHPYIVK  95

         78999*******************************************************

S: 61    ylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHskkvi  120

         +l++++++ +lw+++e++ gG+++ ++  el+++l+E qi++++r++l+aL++lH kk+i

Q: 96    LLGAYYYDGKLWIMIEFCPGGAVDAIML-ELDRGLTEPQIQVVCRQMLEALNFLHGKKII  154

         ***************************9.9******************************

S: 121   HrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe...ekgY  177

         Hrd+ka+n+L+t eg+++L+dfgv+a+  kt +kr++++gtpywmAPEv+ +e   ++ Y

Q: 155   HRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVMCEtmkDTPY  214

         ****************************************************9998999*

S: 178   dekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskefkefvekc  237

         d+kaDiwslGIt+ie+a+ epP+++l+p+++llki+k++pp+l s++k+s ef++f++++

Q: 215   DYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLSPSKWSVEFRDFLKTA  274

         ************************************************************

S: 238   lqknpekRpsasellkhkFl  257

         l+knpe+Rpsa++ll+h+F+

Q: 275   LDKNPETRPSAAQLLEHPFV  294

         *******************7

Domain Sequence
(FASTA)

WEIVGELGDG AFGKVYKAKN KETGALAAAK VIETKSEEEL EDYTVEIDIL ATCDHPYIVK 60

LLGAYYYDGK LWIMIEFCPG GAVDAIMLEL DRGLTEPQIQ VVCRQMLEAL NFLHGKKIIH 120

RDLKAGNVLM TLEGDIRLAD FGVSAKNLKT LQKRDSFIGT PYWMAPEVVM CETMKDTPYD 180

YKADIWSLGI TLIEMAQIEP PHHELNPMRV LLKIAKSDPP TLLSPSKWSV EFRDFLKTAL 240

DKNPETRPSA AQLLEHPFV 259

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005886	; C:plasma membrane
GO:0004674	; F:protein serine/threonine kinase activity
GO:0071593	; P:lymphocyte aggregation
GO:0046777	; P:protein autophosphorylation
GO:2000401	; P:regulation of lymphocyte migration

KEGG

InterPros

IPR022165

; PKK.

Pfam

PF12474

; PKK; 1.

SMARTs

Prosites

Prints

Created Date

20-Feb-2013