EKS-MUP-00067

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00067

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	371.9	1.9E-111	585	878	294

Status

Unreviewed

Ensembl Protein

ENSMPUP00000014898

Gene Name

Cdk12

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000015009	ENSMPUP00000014898	ENSMPUT00000015135

Organism

Mustela putorius furo

Protein Length

1282

Protein Sequence
(FASTA)

MKDRVSGSSK RSNEENEDYG KAQISKSSSN KESRSSKLHK EKTRKERELK SGHKDRSKSH 60

RKRETPKSYK TVDSPKRRSR SPHRKWSDSP KQDDSPSGAS YGQDYDLSPP RSHTSSNYDS 120

YKKSPGSTSR RQSISPPYKE PSAYQSSTRS PSPYSRRQRS VSPYSRRRSS SYERSGSYSG 180

RSPSPYGRRR SSSPFMSKRS LSRSPLPRKS MKSRSRSPAY SRHSSSHSKK KRSGSRSRHS 240

SISPVRLPLN SSLGAELSRK KKERAAAAAA AKMDGKESKG SPIFLPRKEN SLVEAKDSGL 300

ESKKLTRGVK LEKSAPDTEL VNVPHLNTEV KNSLDTGKVK LDENSEKHPI KDLKVQGSRD 360

SKPIALKEDI VTPKETETSE KETPPPVPTV TSPPPPLPTT TPPPQTPPLP PLPPLPAIPQ 420

QPPLPPPQPV FSQVLTSSTS TLPPSTHPRT STLSSQANSQ PLAQVSVKTQ VSVTAAIPHL 480

KTSTLPPLPL PPLLPGDDDM DSPKETPPSK PVKKEKEQRP RHLLTDLPLP PELPGGDPSP 540

PDSPEPKAVT PPQQPYKKRP KICCPRYGER RQTESDWGKR CVDKFDIIGI IGEGTYGQVY 600

KAKDKDTGEL VALKKVRLDN EKEGFPITAI REIKILRQLI HRSVVNMKEI VTDKQDALDF 660

KKDKGAFYLV FEYMDHDLMG LLESGLVHFS EDHIKSFMKQ LMEGLDYCHK KNFLHRDIKC 720

SNILLNNSGQ IKLADFGLAR LYNSEESRPY TNKVITLWYR PPELLLGEER YTPAIDVWSC 780

GCILGELFTK KPIFQANLEL AQLELISRLC GSPCPAVWPD VIKLPYFNTM KPKKQYRRRL 840

REEFSFIPSA ALDLLDHMLT LDPSKRCTAE QTLQSDFLKD VELSKMDPPD LPHWQDCHEL 900

WSKKRRRQRQ SGVVIEEPPP SKASRKETTS GTSAEPVKNS SPAPPQPAPG KVEPGTGDAI 960

GLGDITQQLN QSELAVLLNL LQSQTDLSIP QMAQLLNIHS NPEMQQQLEA LNQSISALTE 1020

ATSQQQDSEP LAPEESLKEA PPALVVQPSA EQTSSEASST PADMQNMLAV LLSQLMKTQE 1080

PAGSLEENSS DKNSGPQGPR RTPTMPQEEA AACPPHILPP EKRPPEPPGP PPPPPPPPLV 1140

EGDLSSAPQE LNPAVTAALL QLLSQPEAEP PGHLPHEHQA LRPMEYSTRP HPNRTYGNTD 1200

GPETGFSATD TDERNSGPAL TESLTQTLVK NRTFSGSVSH LGESSSYQGT GWQQWQEGWP 1260

LRNLVKSISH LASGALDEFS LS 1282

Nucleotide Sequence
(FASTA)

ATGAAGGACC GGGTATCAGG AAGTTCAAAG CGTTCAAATG AAGAGAATGA GGACTATGGG 60

AAGGCACAGA TATCCAAAAG CAGCAGCAAC AAAGAATCCA GGTCATCCAA ACTCCATAAA 120

GAGAAGACCC GGAAAGAACG TGAGTTGAAG TCTGGGCACA AAGACCGGAG TAAAAGTCAT 180

CGGAAAAGGG AAACACCCAA AAGCTACAAA ACAGTGGACA GCCCCAAACG GAGATCCAGG 240

AGTCCTCATA GGAAATGGTC TGACAGCCCC AAGCAAGATG ATAGCCCGTC AGGAGCTTCT 300

TATGGCCAAG ATTATGACCT TAGTCCCCCA AGATCTCACA CTTCTAGTAA TTACGACTCC 360

TACAAGAAGA GTCCTGGAAG TACCTCAAGA AGGCAGTCAA TTAGCCCTCC TTACAAGGAG 420

CCTTCCGCCT ACCAATCCAG CACCCGGTCA CCCAGTCCCT ACAGTAGACG ACAAAGATCT 480

GTGAGTCCCT ATAGTCGGAG ACGTTCTTCC AGCTATGAAA GGAGTGGCTC TTACAGTGGG 540

AGATCACCCA GTCCCTATGG TCGCAGACGG TCCAGCAGCC CTTTCATGAG CAAACGGTCT 600

TTGAGTCGGA GTCCGCTCCC CAGGAAATCC ATGAAGTCAA GAAGCAGAAG TCCTGCATAT 660

TCAAGACACT CATCTTCTCA TAGTAAAAAG AAGAGATCCG GGTCACGCAG TCGACATTCC 720

AGCATCTCAC CTGTCAGGCT TCCATTGAAC TCCAGCTTGG GAGCTGAACT CAGTAGGAAA 780

AAGAAGGAAA GAGCTGCTGC TGCTGCAGCA GCAAAAATGG ATGGAAAGGA ATCCAAGGGT 840

TCACCTATAT TTTTGCCTAG AAAAGAGAAT AGTTTAGTAG AGGCTAAGGA TTCAGGCTTG 900

GAGTCTAAAA AGTTAACCAG AGGTGTAAAA TTGGAAAAAT CTGCCCCAGA TACTGAACTG 960

GTGAATGTAC CACATCTAAA TACAGAAGTT AAAAATTCCT TAGATACAGG GAAAGTAAAA 1020

TTAGATGAGA ACTCTGAGAA GCATCCTATT AAAGATTTGA AAGTGCAGGG ATCAAGAGAC 1080

TCTAAACCCA TAGCATTGAA AGAGGACATT GTTACTCCAA AAGAGACAGA GACATCAGAA 1140

AAGGAGACTC CTCCACCTGT CCCCACAGTT ACTTCTCCTC CACCTCCTTT ACCAACTACT 1200

ACCCCTCCAC CTCAGACACC CCCTTTGCCA CCTTTGCCTC CACTACCAGC TATTCCACAG 1260

CAACCACCTC TGCCTCCTCC CCAACCAGTA TTTAGTCAGG TTCTTACTTC TAGTACTTCA 1320

ACTTTGCCCC CTTCTACTCA CCCAAGGACA TCTACTTTGT CCTCTCAGGC AAATTCTCAG 1380

CCCCTTGCAC AGGTTTCTGT GAAGACTCAA GTATCCGTAA CAGCTGCTAT TCCACACCTA 1440

AAAACTTCAA CGTTGCCTCC TTTACCCCTC CCACCCTTAT TACCAGGAGA CGATGACATG 1500

GATAGTCCAA AAGAAACTCC ACCTTCAAAA CCTGTAAAGA AAGAGAAGGA ACAAAGGCCA 1560

CGTCACTTAC TCACGGACCT CCCTCTCCCT CCAGAACTTC CTGGTGGGGA TCCATCTCCC 1620

CCAGACTCTC CAGAACCAAA GGCAGTTACA CCACCTCAGC AACCATATAA AAAGAGACCA 1680

AAAATTTGTT GTCCTCGTTA TGGAGAAAGA AGACAAACAG AAAGTGACTG GGGAAAACGC 1740

TGTGTAGATA AGTTCGACAT TATTGGGATT ATTGGAGAGG GAACCTATGG CCAAGTATAT 1800

AAAGCCAAGG ACAAAGACAC AGGAGAGCTA GTGGCCCTGA AAAAGGTGAG ACTGGACAAT 1860

GAGAAGGAGG GCTTCCCAAT CACAGCCATT CGTGAGATCA AAATCCTTCG TCAGCTAATC 1920

CACCGAAGTG TTGTTAACAT GAAGGAAATT GTTACGGATA AACAGGATGC ACTGGATTTC 1980

AAGAAGGACA AAGGTGCCTT TTACCTTGTA TTTGAGTATA TGGACCATGA CTTAATGGGA 2040

CTGTTAGAAT CTGGTTTGGT ACACTTTTCT GAGGACCATA TCAAGTCATT CATGAAACAG 2100

CTAATGGAAG GATTGGATTA CTGTCACAAA AAGAATTTCC TGCATCGGGA TATTAAGTGT 2160

TCTAACATTT TGCTGAACAA CAGTGGGCAA ATCAAACTAG CAGATTTTGG ACTTGCACGG 2220

CTCTATAACT CTGAAGAGAG TCGCCCTTAC ACAAACAAAG TCATCACTTT GTGGTACCGA 2280

CCTCCAGAAC TTCTGCTGGG AGAGGAGCGT TATACACCAG CCATTGATGT TTGGAGCTGT 2340

GGATGCATCC TTGGGGAATT GTTCACAAAG AAGCCTATTT TTCAAGCCAA TCTGGAACTG 2400

GCTCAGCTGG AGCTGATCAG TCGACTCTGT GGTAGCCCTT GTCCAGCTGT GTGGCCTGAT 2460

GTTATCAAGC TGCCCTACTT CAATACCATG AAACCGAAGA AACAATATAG AAGGCGTCTA 2520

CGAGAAGAAT TCTCTTTCAT TCCTTCAGCA GCACTTGATT TACTGGACCA CATGCTAACA 2580

CTAGATCCTA GCAAACGTTG CACAGCTGAA CAGACTTTAC AGAGTGACTT CCTTAAAGAT 2640

GTTGAGCTCA GCAAAATGGA TCCTCCAGAC CTCCCCCACT GGCAAGATTG CCATGAATTA 2700

TGGAGTAAGA AACGGCGACG ACAGCGACAG AGTGGTGTTG TGATAGAAGA GCCACCTCCT 2760

TCCAAAGCCT CTCGGAAAGA AACTACCTCA GGGACAAGTG CTGAGCCTGT GAAGAATAGC 2820

AGCCCAGCAC CACCTCAGCC TGCTCCTGGC AAGGTGGAGC CTGGGACTGG GGATGCAATA 2880

GGCCTCGGTG ACATCACCCA GCAGTTGAAT CAAAGTGAAT TGGCAGTGTT ACTGAATCTG 2940

CTGCAGAGCC AAACCGACCT GAGCATCCCT CAAATGGCTC AGCTGCTTAA CATCCACTCC 3000

AACCCAGAGA TGCAGCAGCA GCTGGAGGCC CTGAACCAAT CCATCAGTGC CCTAACTGAA 3060

GCCACTTCCC AGCAGCAGGA CTCAGAGCCC TTGGCCCCAG AAGAGTCTTT GAAGGAGGCA 3120

CCTCCTGCCC TAGTGGTCCA GCCTTCAGCA GAACAGACAA GCTCTGAAGC TTCAAGCACA 3180

CCAGCTGACA TGCAGAATAT GTTGGCAGTT CTTTTGAGTC AGCTGATGAA AACCCAGGAG 3240

CCAGCAGGCA GCCTGGAGGA AAACAGCAGT GACAAGAACA GTGGGCCACA GGGGCCCCGA 3300

AGAACTCCCA CAATGCCACA GGAGGAGGCA GCAGCATGTC CTCCTCACAT TCTTCCACCA 3360

GAGAAGAGGC CCCCTGAGCC CCCCGGACCT CCACCGCCGC CACCTCCACC CCCTCTGGTT 3420

GAAGGCGATC TTTCCAGCGC CCCCCAGGAG TTGAACCCAG CCGTGACAGC CGCCTTGCTG 3480

CAACTTTTAT CCCAGCCTGA AGCAGAGCCT CCTGGCCACC TGCCACATGA GCACCAGGCC 3540

TTGAGACCAA TGGAATACTC CACCCGACCC CATCCCAACA GGACTTACGG AAACACTGAT 3600

GGGCCTGAAA CAGGGTTCAG TGCCACTGAC ACTGATGAAC GCAACTCTGG TCCAGCTTTG 3660

ACAGAATCCT TGACCCAGAC CCTGGTGAAG AACAGGACCT TCTCAGGCTC TGTGAGCCAC 3720

CTTGGGGAGT CCAGCAGTTA CCAGGGCACA GGGTGGCAGC AGTGGCAGGA AGGATGGCCC 3780

TTGAGGAATT TGGTGAAATC CATCAGTCAC CTGGCATCTG GAGCTCTTGA CGAGTTCAGT 3840

CTTTCATAG 3849

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         ++ +  igeGtyg+vykakdk+tge+vAlKk+rl++ekeg+pita+rEi++l++l h+ +

Q: 585   FDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIHRSV  644

         667889******************************************************

S: 61    vkLlevva.........kdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlle  111

         v+++e+v+         kdk  +yLvfe++++dL+ ll++    ++s++++ks+++ql+e

Q: 645   VNMKEIVTdkqdaldfkKDKGAFYLVFEYMDHDLMGLLESGLV-HFSEDHIKSFMKQLME  703

         ****************8899********************999.****************

S: 112   glaylHsnkilHRDlKpqNlLiskegklklaDfGlarafssplk.tytkevvTlwYraPe  170

         gl+y+H++++lHRD+K++N+L++++g++klaDfGlar ++s+++  yt++v+TlwYr+Pe

Q: 704   GLDYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESrPYTNKVITLWYRPPE  763

         ***************************************7766527**************

S: 171   lLlgakeYstavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsk  230

         lLlg+++Y+ a+D+Ws+gcil el+t+kp+fq++ e  qle i++l+g+p  +vwp+v k

Q: 764   LLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLELISRLCGSPCPAVWPDVIK  823

         ************************************************************

S: 231   lpeykksfpkkkkk.klkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         lp +++  pkk+++ +l+e+++ + ++aldll+++l+ldp+kR++a+++lq++++

Q: 824   LPYFNTMKPKKQYRrRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFL  878

         *****7777777777******9999**************************9985

Domain Sequence
(FASTA)

FDIIGIIGEG TYGQVYKAKD KDTGELVALK KVRLDNEKEG FPITAIREIK ILRQLIHRSV 60

VNMKEIVTDK QDALDFKKDK GAFYLVFEYM DHDLMGLLES GLVHFSEDHI KSFMKQLMEG 120

LDYCHKKNFL HRDIKCSNIL LNNSGQIKLA DFGLARLYNS EESRPYTNKV ITLWYRPPEL 180

LLGEERYTPA IDVWSCGCIL GELFTKKPIF QANLELAQLE LISRLCGSPC PAVWPDVIKL 240

PYFNTMKPKK QYRRRLREEF SFIPSAALDL LDHMLTLDPS KRCTAEQTLQ SDFL 294

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>