EKS-MUP-00305

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00305

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	364.8	2.4E-109	25	289	265

Status

Unreviewed

Ensembl Protein

ENSMPUP00000017036

Gene Name

Tnik

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000017145	ENSMPUP00000017036	ENSMPUT00000017290

Organism

Mustela putorius furo

Protein Length

1360

Protein Sequence
(FASTA)

MASDSPARSL DEIDLSALRD PAGIFELVEL VGNGTYGQVY KGRHVKTGQL AAIKVMDVTG 60

DEEEEIKQEI NMLKKYSHHR NIATYYGAFI KKNPPGMDDQ LWLVMEFCGA GSVTDLIKNT 120

KGNTLKEEWI AYICREILRG LSHLHQHKVI HRDIKGQNVL LTENAEVKLV DFGVSAQLDR 180

TVGRRNTFIG TPYWMAPEVI ACDENPDATY DFKSDLWSLG ITAIEMAEGA PPLCDMHPMR 240

ALFLIPRNPA PRLKSKKWSK KFQSFIESCL VKNHSQRPAT EQLMKHPFIR DQPNERQVRI 300

QLKDHIDRTK KKRGEKDETE YEYSGSEEEE EENDSGEPSS ILNLPGESTL RRDFLRLQLA 360

NKERSEALRR QQLEQQQREN EEHKRQLLAE RQKRIEEQKE QRRRLEEQQR REKELRKQQE 420

REQRRHYEEQ MRREEERRRA EHEQEYIRRQ LEEEQRQLEI LQQQLLHEQA LLLEYKRKQL 480

EEQRQAERLQ RQLKQERDYL VSLQHQRQEQ RPVEKKPLYH YKEGMSPSEK PAWAKEVEER 540

SRLNRQSSPA MPHKVANRIS DPNLPPRSES FSISGVQPAR TPPMLRPVDP QIPHLVAVKS 600

QGPALTASQS VHEQPTKGLS GFQEALNVTS HRVEMPRQNS DPTSENPPLP TRIEKFDRSS 660

WLRQEEDIPP KVPQRTTSIS PALARKNSPG NGSALGPRLG SQPIRASNPD LRRTEPILES 720

PLQRTSSGSS SSSSTPSSQP SSQGGSQPGS QAGSSERTRV RANSKSEGSP VLPHEPSKVK 780

PEESRDITRP SRPASYKKAI DEDLTALAKE LRELRIEETN RPLKKVTDYS SSSEESESSD 840

EEEEDGESET HDGTVAVSDI PRLIPTGAPG NTEQYNVGMV GTHGLETSHA DTFSSSISRE 900

GTLMIRETSG EKKRSGHSDS NGFAGHINLP DLVQQSHSPA GTPTEGLGRV STHSQEMESG 960

TEYGMGSSTK ASFTPFVDPR VYQTSPTDEE EEDEESSAAA LFTSELLRQE QAKLNEARKI 1020

SVVNVNPTNI RPHSDTPEIR KYKKRFNSEI LCAALWGVNL LVGTENGLML LDRSGQGKVY 1080

NLINRRRFQQ MDVLEGLNVL VTISGKKNKL RVYYLSWLRN RILHNDPEVE KKQGWITVGD 1140

LEGCIHYKVV KYERIKFLVI ALKNAVEIYA WAPKPYHKFM AFKSFSDLQH KPLLVDLTVE 1200

EGQRLKVIFG SHTGFHVIDV DSGNSYDIYI PSHIQGNITP HAIVILPKTD GMEMLVCYED 1260

EGVYVNTYGR ITKDVVLQWG EMPTSVAYIH SNQIMGWGEK AIEIRSVETG HLDGVFMHKR 1320

AQRLKFLCER NDKVFFASVR SGGSSQVFFM TLNRNSMMNW 1360

Nucleotide Sequence
(FASTA)

ATGGCGAGCG ACTCCCCGGC TCGCAGCCTG GATGAAATCG ATCTCTCGGC TCTGAGGGAC 60

CCTGCAGGGA TCTTTGAATT AGTGGAACTT GTTGGAAATG GAACATATGG ACAAGTTTAT 120

AAGGGTCGTC ATGTTAAAAC GGGCCAGCTT GCAGCCATTA AAGTTATGGA CGTCACAGGG 180

GATGAAGAGG AGGAAATCAA ACAAGAAATT AACATGTTGA AGAAATATTC TCATCACCGG 240

AATATTGCAA CTTACTATGG TGCTTTTATC AAAAAGAACC CACCAGGCAT GGATGACCAA 300

CTTTGGTTGG TGATGGAGTT TTGTGGTGCT GGCTCTGTCA CTGACCTGAT CAAGAACACG 360

AAAGGTAACA CCTTGAAGGA GGAGTGGATT GCATACATCT GCAGGGAGAT CTTACGAGGG 420

CTGAGTCATC TGCACCAGCA TAAAGTGATT CATCGAGATA TTAAAGGGCA GAATGTCTTG 480

CTAACTGAGA ATGCAGAAGT TAAACTAGTG GACTTTGGTG TCAGTGCCCA GCTTGATCGA 540

ACAGTGGGCA GGAGAAATAC CTTCATCGGG ACCCCTTACT GGATGGCACC AGAAGTCATT 600

GCCTGCGACG AAAACCCAGA CGCCACATAT GATTTCAAGA GTGACCTGTG GTCGCTGGGA 660

ATCACCGCTA TCGAGATGGC AGAAGGTGCT CCCCCTCTCT GCGACATGCA TCCCATGAGA 720

GCCCTCTTCC TCATCCCCCG GAACCCAGCA CCTCGCCTGA AGTCGAAGAA GTGGTCAAAA 780

AAATTCCAGT CATTTATTGA GAGCTGCTTG GTAAAGAATC ACAGCCAGCG ACCAGCAACA 840

GAACAATTGA TGAAGCATCC ATTTATACGA GACCAACCTA ACGAACGACA GGTCCGCATT 900

CAACTCAAGG ACCATATCGA CAGAACAAAG AAGAAGCGAG GAGAGAAAGA TGAGACGGAG 960

TACGAGTACA GCGGAAGTGA GGAAGAAGAG GAGGAGAATG ACTCAGGAGA GCCCAGCTCC 1020

ATCCTGAACC TGCCTGGGGA GTCCACGCTG CGGCGGGACT TCCTGAGGCT CCAGCTGGCC 1080

AACAAGGAGC GCTCGGAGGC CCTGCGGCGG CAGCAGCTGG AGCAGCAGCA GCGGGAGAAC 1140

GAGGAGCACA AGCGGCAGCT GCTGGCCGAG CGCCAGAAGC GCATAGAGGA GCAGAAGGAG 1200

CAGCGCCGGC GGCTGGAGGA GCAACAGCGG CGGGAGAAGG AGCTGCGGAA GCAGCAGGAG 1260

AGAGAGCAGC GCCGGCACTA CGAGGAGCAG ATGCGCCGGG AGGAGGAGAG GAGGCGCGCG 1320

GAGCACGAGC AGGAGTACAT CAGGCGACAG TTAGAGGAGG AGCAGAGACA GTTAGAGATC 1380

TTGCAGCAGC AGCTACTGCA TGAACAAGCT CTACTTCTGG AATATAAGCG CAAACAATTG 1440

GAAGAACAGA GACAAGCAGA AAGACTGCAG AGACAGCTAA AGCAAGAGAG AGACTACTTG 1500

GTGTCTCTCC AGCATCAGCG GCAGGAGCAG AGGCCGGTGG AGAAGAAGCC ACTGTACCAT 1560

TACAAAGAAG GGATGAGTCC TAGTGAGAAA CCAGCATGGG CCAAGGAGGT GGAAGAGCGG 1620

TCAAGGCTCA ACCGGCAGAG TTCTCCGGCC ATGCCTCATA AGGTTGCCAA CAGAATCTCT 1680

GACCCCAACC TGCCCCCGAG GTCGGAGTCC TTCAGTATCA GCGGGGTTCA GCCTGCTCGG 1740

ACACCCCCCA TGCTCAGACC CGTCGATCCC CAGATTCCAC ATCTGGTAGC GGTAAAATCC 1800

CAGGGACCTG CCTTGACCGC CTCCCAGTCA GTGCACGAGC AGCCCACCAA GGGCCTCTCT 1860

GGGTTTCAGG AGGCTCTGAA CGTGACCTCC CACCGCGTTG AGATGCCACG CCAGAACTCG 1920

GATCCCACCT CCGAAAACCC TCCTCTCCCC ACTCGCATTG AGAAGTTTGA CCGAAGCTCT 1980

TGGTTACGAC AGGAAGAAGA CATTCCACCA AAGGTGCCTC AAAGAACAAC TTCTATATCC 2040

CCAGCGTTAG CCAGAAAGAA TTCTCCTGGA AATGGTAGTG CTTTGGGACC CAGACTAGGA 2100

TCTCAACCCA TCAGAGCAAG CAACCCTGAC CTCCGCAGAA CTGAGCCCAT CTTGGAGAGC 2160

CCCTTGCAGA GGACCAGCAG TGGCAGTTCC TCCAGCTCCA GCACCCCTAG CTCCCAGCCT 2220

AGCTCCCAAG GAGGCTCACA GCCTGGATCG CAAGCAGGAT CCAGTGAACG GACCAGAGTT 2280

CGAGCCAATA GTAAGTCGGA AGGATCTCCT GTGCTCCCCC ATGAGCCTTC CAAGGTGAAG 2340

CCAGAAGAAT CCAGAGACAT TACCCGACCT AGTCGACCAG CTAGCTATAA GAAAGCAATA 2400

GATGAGGATC TGACGGCATT AGCCAAAGAA TTACGAGAAC TTCGGATCGA AGAAACAAAC 2460

CGCCCACTGA AGAAGGTGAC TGATTACTCC TCCTCCAGTG AGGAGTCGGA AAGTAGCGAT 2520

GAAGAGGAGG AAGATGGAGA GAGCGAGACC CATGATGGGA CAGTGGCTGT CAGTGACATA 2580

CCCAGACTCA TACCCACAGG AGCCCCGGGA AACACGGAGC AGTACAATGT GGGAATGGTA 2640

GGCACTCACG GGCTGGAGAC CTCACACGCG GACACTTTCA GCAGCAGTAT TTCAAGAGAA 2700

GGAACCCTGA TGATAAGAGA GACGTCTGGA GAGAAGAAGC GATCTGGCCA CAGTGACAGC 2760

AATGGCTTTG CTGGCCACAT CAATCTCCCA GACCTGGTGC AGCAGAGCCA CTCCCCAGCC 2820

GGGACACCAA CGGAGGGCCT GGGGCGCGTC TCCACCCATT CCCAGGAGAT GGAATCTGGG 2880

ACTGAATACG GCATGGGGAG CAGCACTAAG GCCTCCTTCA CTCCCTTTGT GGACCCCAGA 2940

GTGTACCAAA CGTCTCCCAC TGATGAAGAG GAAGAGGACG AAGAATCATC AGCTGCGGCT 3000

CTGTTTACTA GCGAACTTCT TAGGCAAGAA CAGGCCAAAC TCAATGAAGC ACGAAAGATT 3060

TCAGTGGTAA ACGTAAACCC AACCAACATT CGACCTCATA GCGACACACC TGAAATCAGA 3120

AAATACAAGA AACGATTCAA CTCGGAGATA CTCTGTGCAG CTCTGTGGGG TGTGAACCTC 3180

CTGGTGGGAA CAGAAAATGG CCTGATGCTT TTGGACCGAA GTGGGCAAGG CAAAGTCTAT 3240

AATCTGATCA ACCGGAGGCG ATTTCAGCAG ATGGACGTGT TAGAGGGACT GAATGTCCTG 3300

GTGACGATAT CAGGAAAGAA GAACAAACTA CGAGTTTACT ATCTTTCATG GTTAAGAAAC 3360

AGAATACTAC ACAACGACCC AGAAGTGGAA AAGAAACAAG GCTGGATCAC AGTTGGGGAC 3420

TTGGAAGGCT GCATACATTA CAAAGTTGTT AAATATGAAA GGATTAAATT CCTAGTGATT 3480

GCCTTAAAGA ATGCTGTGGA AATATATGCC TGGGCTCCTA AACCATATCA TAAGTTCATG 3540

GCATTTAAGT CTTTTTCAGA TCTCCAGCAC AAGCCACTGC TTGTTGATCT CACAGTAGAA 3600

GAAGGTCAAA GATTGAAGGT TATTTTTGGT TCACACACTG GTTTTCATGT AATTGATGTT 3660

GATTCAGGAA ACTCTTATGA TATCTACATA CCATCTCATA TTCAGGGCAA TATCACTCCT 3720

CATGCCATTG TCATCTTGCC TAAAACAGAT GGAATGGAAA TGCTTGTTTG CTATGAGGAT 3780

GAGGGGGTGT ATGTAAACAC CTATGGCCGG ATAACTAAGG ATGTGGTGCT CCAATGGGGA 3840

GAAATGCCCA CGTCCGTGGC CTACATTCAT TCCAATCAGA TAATGGGCTG GGGCGAGAAA 3900

GCTATTGAGA TCCGGTCAGT GGAAACAGGA CATTTGGATG GAGTATTTAT GCATAAGCGA 3960

GCTCAAAGGT TAAAGTTTCT ATGTGAAAGA AATGATAAGG TATTTTTTGC ATCCGTGCGA 4020

TCTGGAGGAA GTAGCCAAGT GTTTTTCATG ACCCTCAACA GAAATTCCAT GATGAACTGG 4080

TAA 4083

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkklkh.pniv  59

         +el+e +g+G++g+vy++r++ktg+l+aik+++++  +++ee+++ei++lkk++h +ni

Q: 25    FELVELVGNGTYGQVYKGRHVKTGQLAAIKVMDVTG-DEEEEIKQEINMLKKYSHhRNIA  83

         899********************************8.999*************998****

S: 60    eylesflk......eeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLey  113

         +y+++f+k      +++lwlvme++ +Gs++dl+k+++ ++lkEe+iayi+re+l++L++

Q: 84    TYYGAFIKknppgmDDQLWLVMEFCGAGSVTDLIKNTKGNTLKEEWIAYICREILRGLSH  143

         ************************************************************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaqe  173

         lH++kviHrdik++n+Llte++eVkL+dfgv+aql++t+ +r+t++gtpywmAPEvia++

Q: 144   LHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACD  203

         ************************************************************

S: 174   ...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfskef  230

            + +Yd k+D+wslGItaie+aeg+pP++d++p++al++i++n++p+lksk k+sk+f

Q: 204   enpDATYDFKSDLWSLGITAIEMAEGAPPLCDMHPMRALFLIPRNPAPRLKSK-KWSKKF  262

         999999********************************************888.******

S: 231   kefvekclqknpekRpsasellkhkFl  257

         ++f+e+cl kn ++Rp++++l+kh+F+

Q: 263   QSFIESCLVKNHSQRPATEQLMKHPFI  289

         **************************7

Domain Sequence
(FASTA)

FELVELVGNG TYGQVYKGRH VKTGQLAAIK VMDVTGDEEE EIKQEINMLK KYSHHRNIAT 60

YYGAFIKKNP PGMDDQLWLV MEFCGAGSVT DLIKNTKGNT LKEEWIAYIC REILRGLSHL 120

HQHKVIHRDI KGQNVLLTEN AEVKLVDFGV SAQLDRTVGR RNTFIGTPYW MAPEVIACDE 180

NPDATYDFKS DLWSLGITAI EMAEGAPPLC DMHPMRALFL IPRNPAPRLK SKKWSKKFQS 240

FIESCLVKNH SQRPATEQLM KHPFI 265

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>