EKS-MUP-00215

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00215

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/NKF3	551.1	9.2E-166	1331	1665	335

Status

Unreviewed

Ensembl Protein

ENSMPUP00000017221

UniProt Accession

G9L3U1;

Protein Name

Protein Synonyms/Alias

Putative uncharacterized protein;

Gene Name

C230081A13Rik

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000017331	ENSMPUP00000017221	ENSMPUT00000017477

Organism

Mustela putorius furo

Functional Description

Protein Length

1748

Protein Sequence
(FASTA)

MSACNTFTEH VWKPGECKNC FKPKSLHQLP PDPEKAPITH GNVKTNANHS NNHRMRNTGN 60

FRPPVAKKPT IAVKPTMMVA DGQSVCGELS IQEHCENKPV IIGWNRNRTP LNQKPLNNNN 120

EDDIEGFSHV PKPYGNNDSA KKVSNNNNGL TDVLKEIAGL DAIPQIRGNE TNSRETFLGR 180

INDCYKRSLE RKLPPSCMMG GIKDTQGKHV ILSGSTEVIS NEGGRFCYPE FSSGEESEED 240

VLFSNMEEEH ESWDESDEEL LAMEIRMRGQ PRFANFRANT LSPVRFFVDK KWNTVPLRNK 300

SLQRICAVDY DDSYDEILNG YEENSVASYG PGSVQSMASS DSASPGSSLT EESRSETASS 360

LSQKICNGGV SPGNPGDSKD MKEREPNCES LSGNSQEKDS SQAPKSSVKV PETHKAVLAL 420

RLEEKDGKIA VQTEKQESKA STDIAGQAIT INLVPVEEQA KPYRVVNLEQ PLCKPYTIVD 480

VSAAMASEHL EGPVNSPKTK ISSSTPNSPV TSPALTSGQT GAHFQNSSAI RYQEVWTSST 540

SPRQKIPKVE LVSGGTGPNI PPRKNCHKSA PTSPTTTNIS SKTIPVKSPN LSEIKFNSYN 600

NAGMPPFPII IHDEPTYARS SKNAIKVPIV INPNAYDNLA IYKSFLGTSG ELSVKEKTTS 660

IISHTYEEIE TDSKVSDNST SKPTDCPQAK GFSNSTERKR GSVAQKVQEF NSCLNRGQSS 720

PQKSYSSSHS SPTKIQRTTQ EPGAKTEGPQ ESPMTCTTSS SSREKASTVL SQIVASIQPP 780

QSPPEMPQSG PKACSVEELY AVPPDADAKS TPKSTPARPK SLFTAQPGAE AEAPQTTESP 840

TTKARKDPLT KPVTSPLSKL VANPQSEPPP PFPPPRSTSS PYHASNLLQR HFTNWTKPTS 900

PTRSTEAESI LHSEGSRRAA DAKPKRWISF KSFFRRRKTD EEEDKEKDRE KGKLVGLDGT 960

VIHMLPPPPV QRHHWFTEAK GESSEKAAIV FMYRCDPAQS QPSADQKARA DQAAVREKDG 1020

AEDGLLQDSE KKKRSHSSPS QVPKKIISHK THEVTEDFSP RDPRSVVARQ DDGACPPITA 1080

ALPLPGLEGD EEKEDVSDTI DLNPCSATYS NLGQSRAAMI PPKHPRQPKG TLDDGIVFTE 1140

KTDQEAPNAS QPTPPPLPKK MIIRANTEPI PKDLQKSMET SLCVMANPTY DIDPNWDASS 1200

AGSSISYELK GLDIESYDSL ERPLHKERPV PSAANSISSL TTLSIKDRFS NSMESLSSRR 1260

GPSCRQGRSM QKPQRQALYR GLENREEVVG KIRSLHTDAL KKLAIKCEDL FMAGQKDQLR 1320

FGVDSWSDFR LTSDKPCCEA GDAVYYTASY AKDPLNNYAV KICKSKAKES QQYYHSLAVR 1380

QSLAVHFNIQ QDCGHFLAEV PNRLLPWDDP DAPEEEEDEM EEAEEEVKGE TDGKSPEPCS 1440

ETEPSQKASQ GLISRKQRSH VVVITREVPY LTVADFVRDS LGQHGKSPDL YERQVCLLLL 1500

QLCSGLEHLK PYHVTHCDLR LENLLLVHYQ PGGTSQGLGP AEASPTSSCS TRLIVSNFSQ 1560

AKQKSHLVDP EILRDQSRLA PEIITATQYK KCDEFQTGIL IYEMLHLPNP FDENPELKEK 1620

EYTRADLPRI PLRSPYSRGL QQLASCLLNP NPSERILISD AKGILQCLLW GPREDLFQTL 1680

TISPSPAQRS ALLQNWLDIK RTLLMIKFAE KSLDREGGVN LEDWLCAQYL AFATPDSLGC 1740

IVKTLQHR 1748

Nucleotide Sequence
(FASTA)

ATGTCTGCTT GTAACACCTT TACTGAACAC GTTTGGAAAC CTGGTGAATG CAAGAACTGC 60

TTTAAACCTA AAAGCTTGCA CCAGCTTCCC CCAGACCCTG AGAAGGCACC CATCACCCAT 120

GGCAATGTGA AAACTAATGC CAATCACAGT AACAACCACC GCATGAGGAA CACTGGAAAT 180

TTCCGTCCTC CTGTGGCTAA AAAACCCACT ATAGCTGTGA AGCCCACTAT GATGGTGGCA 240

GATGGGCAAA GTGTATGTGG TGAACTTAGT ATCCAAGAAC ACTGTGAGAA CAAACCTGTC 300

ATCATAGGAT GGAACCGAAA CAGGACACCC TTGAATCAGA AACCACTTAA TAATAATAAT 360

GAAGATGACA TTGAAGGCTT TAGCCATGTT CCTAAGCCTT ATGGCAATAA TGATAGTGCA 420

AAGAAGGTAT CAAATAACAA TAATGGACTA ACGGATGTGT TAAAGGAGAT AGCAGGCTTG 480

GATGCCATCC CTCAGATAAG AGGAAATGAA ACAAACTCCA GAGAAACATT CTTAGGAAGA 540

ATAAATGATT GCTATAAAAG ATCACTGGAA AGAAAGCTTC CACCGAGTTG CATGATGGGT 600

GGGATCAAGG ATACTCAAGG CAAGCACGTG ATTCTGAGTG GGAGCACAGA AGTGATCAGT 660

AATGAAGGGG GCCGGTTCTG TTACCCAGAG TTTTCTAGCG GCGAGGAGAG TGAAGAAGAT 720

GTACTTTTCA GTAACATGGA GGAGGAGCAT GAGAGCTGGG ATGAGAGCGA TGAAGAGCTG 780

TTGGCCATGG AGATTCGCAT GAGAGGGCAA CCGCGCTTTG CTAACTTCAG GGCAAATACT 840

TTGTCTCCTG TTCGATTCTT TGTGGACAAA AAATGGAATA CAGTCCCCTT GCGAAATAAG 900

TCCCTGCAGA GGATCTGTGC TGTCGACTAT GATGACAGCT ATGATGAAAT CCTAAACGGC 960

TATGAAGAAA ACTCTGTGGC CTCCTATGGA CCAGGAAGTG TTCAGAGCAT GGCATCCTCT 1020

GACTCTGCAT CACCAGGTTC TTCTTTAACA GAAGAATCGC GTTCTGAGAC AGCCAGTAGT 1080

TTATCCCAGA AGATCTGTAA TGGGGGAGTA TCTCCGGGTA ACCCCGGAGA TTCTAAGGAC 1140

ATGAAAGAAA GGGAGCCCAA TTGTGAAAGT CTCTCTGGTA ATAGTCAGGA GAAGGACTCC 1200

TCACAAGCAC CTAAAAGCTC AGTAAAAGTT CCAGAAACAC ACAAAGCCGT CCTTGCTCTC 1260

CGACTAGAAG AGAAGGATGG CAAAATTGCC GTACAAACTG AGAAGCAAGA AAGTAAAGCC 1320

TCTACAGATA TCGCTGGCCA AGCCATAACC ATAAACCTCG TCCCCGTGGA AGAGCAAGCA 1380

AAGCCTTACC GAGTTGTCAA TCTGGAACAG CCACTGTGCA AGCCATATAC TATCGTGGAC 1440

GTGTCGGCAG CCATGGCCAG TGAGCACCTC GAAGGCCCTG TTAACAGCCC CAAGACAAAA 1500

ATCTCATCTT CTACTCCAAA CTCTCCGGTG ACATCGCCTG CACTGACATC AGGACAAACA 1560

GGTGCCCATT TCCAAAACTC CAGTGCAATA CGATACCAGG AAGTGTGGAC TTCCAGCACC 1620

AGCCCGCGAC AAAAGATACC CAAGGTGGAA TTGGTTAGCG GTGGAACTGG GCCAAACATC 1680

CCTCCGAGGA AAAACTGTCA CAAGTCAGCA CCCACTTCAC CTACAACAAC AAACATTTCC 1740

TCTAAAACTA TCCCTGTTAA GTCACCCAAT CTGTCCGAAA TAAAATTCAA TAGTTACAAT 1800

AATGCTGGTA TGCCACCTTT TCCAATTATC ATTCATGATG AGCCGACTTA TGCTCGGAGT 1860

TCCAAAAATG CCATCAAAGT CCCCATTGTC ATCAATCCAA ATGCGTATGA CAATCTAGCC 1920

ATTTACAAAA GTTTTCTCGG AACAAGTGGA GAACTCTCGG TGAAGGAAAA AACTACCAGT 1980

ATAATAAGCC ATACTTATGA AGAAATCGAA ACTGACAGCA AAGTGTCCGA TAACAGCACC 2040

AGCAAACCTA CTGACTGTCC CCAAGCCAAG GGGTTTTCCA ACAGCACAGA GCGTAAAAGG 2100

GGCTCAGTGG CTCAAAAGGT TCAGGAGTTT AACAGCTGTC TTAACAGAGG TCAGTCTTCA 2160

CCGCAGAAAA GCTATAGTTC TAGCCACAGC TCCCCAACAA AGATCCAGAG AACCACTCAA 2220

GAACCTGGGG CCAAAACCGA AGGCCCTCAG GAGTCTCCGA TGACGTGCAC CACCAGCAGC 2280

AGCAGCAGGG AGAAAGCGAG CACGGTGCTT TCTCAGATTG TGGCTTCTAT CCAGCCACCG 2340

CAGTCCCCTC CAGAAATGCC CCAGTCTGGC CCGAAAGCAT GCAGCGTGGA AGAGCTGTAC 2400

GCGGTTCCTC CAGACGCCGA TGCTAAGAGT ACCCCTAAGA GTACACCAGC CCGACCCAAA 2460

TCTCTCTTCA CGGCTCAGCC CGGTGCTGAA GCTGAAGCCC CGCAGACCAC AGAAAGCCCG 2520

ACGACCAAAG CACGGAAAGA TCCGCTCACA AAGCCGGTCA CCAGCCCTCT CTCCAAATTA 2580

GTGGCCAACC CCCAGAGCGA GCCACCACCT CCCTTTCCCC CACCTCGCTC TACTTCCTCC 2640

CCTTATCATG CAAGCAACCT TCTGCAGAGG CATTTCACCA ACTGGACCAA GCCCACCAGT 2700

CCTACCCGGT CAACAGAAGC TGAATCGATT TTGCACTCGG AAGGCAGCAG GCGGGCCGCT 2760

GATGCGAAAC CTAAGCGCTG GATATCATTT AAAAGCTTCT TCCGCCGCCG GAAAACAGAT 2820

GAGGAAGAGG ATAAAGAGAA AGACCGAGAG AAAGGAAAAC TGGTGGGCCT GGATGGCACA 2880

GTCATCCACA TGCTGCCGCC ACCTCCAGTC CAGCGCCATC ACTGGTTCAC AGAGGCCAAA 2940

GGAGAGTCCA GTGAGAAGGC GGCCATTGTC TTCATGTACA GGTGCGATCC TGCCCAAAGC 3000

CAGCCCAGCG CGGATCAGAA GGCCAGAGCA GACCAGGCAG CCGTCAGAGA GAAGGATGGG 3060

GCAGAGGACG GGTTACTGCA GGACTCAGAG AAGAAGAAAA GGAGTCATTC TTCTCCATCA 3120

CAGGTTCCTA AAAAAATCAT CAGTCACAAG ACCCATGAAG TGACAGAGGA CTTCTCTCCT 3180

CGGGATCCAA GATCCGTTGT TGCGAGGCAA GATGACGGAG CCTGCCCTCC CATCACAGCA 3240

GCCTTGCCCC TACCTGGACT GGAAGGGGAC GAGGAAAAAG AAGACGTTTC AGATACTATT 3300

GACCTGAATC CCTGTAGTGC AACCTACAGC AACTTAGGGC AATCTAGAGC AGCCATGATA 3360

CCACCCAAGC ATCCAAGGCA GCCTAAGGGA ACTTTGGATG ATGGCATTGT CTTCACTGAG 3420

AAAACAGACC AAGAAGCACC TAATGCTTCC CAACCTACGC CACCCCCACT GCCAAAGAAA 3480

ATGATCATAA GAGCCAATAC AGAACCAATC CCCAAAGACC TCCAAAAATC CATGGAAACA 3540

AGTCTTTGTG TAATGGCTAA TCCCACCTAT GATATTGACC CCAACTGGGA TGCCAGTAGT 3600

GCTGGTTCTT CCATCAGTTA CGAACTCAAG GGACTGGACA TTGAGTCTTA TGACTCCTTG 3660

GAAAGACCTT TGCACAAGGA GAGACCTGTT CCCTCAGCAG CAAACAGTAT CTCCAGCTTA 3720

ACCACTCTCA GTATTAAGGA TAGATTTTCC AACAGCATGG AGTCCCTGTC TAGCCGGCGT 3780

GGTCCCTCTT GCAGACAGGG ACGAAGCATG CAGAAGCCAC AGAGACAAGC ACTTTATCGA 3840

GGACTTGAGA ATCGGGAAGA AGTTGTGGGT AAAATCCGAA GCCTTCATAC AGATGCCTTG 3900

AAGAAACTGG CTATAAAATG TGAAGACCTC TTCATGGCTG GACAGAAAGA CCAGCTCCGT 3960

TTTGGGGTGG ACAGCTGGTC AGACTTCAGG CTAACCAGCG ACAAGCCATG CTGTGAGGCA 4020

GGCGATGCAG TTTACTATAC AGCTTCATAT GCAAAAGATC CACTTAATAA CTATGCAGTC 4080

AAGATCTGTA AGAGCAAAGC GAAAGAGTCG CAGCAGTACT ATCACAGCTT GGCTGTCCGG 4140

CAGAGTCTGG CTGTCCATTT CAACATCCAG CAGGACTGTG GTCATTTCCT TGCAGAAGTC 4200

CCTAATCGTC TGCTTCCCTG GGATGATCCT GATGCCCCTG AAGAGGAAGA GGATGAAATG 4260

GAAGAAGCTG AAGAAGAGGT GAAAGGAGAA ACTGATGGGA AAAGCCCGGA GCCCTGCTCT 4320

GAAACAGAGC CATCCCAGAA AGCAAGCCAG GGGCTCATCA GCAGGAAGCA GAGAAGCCAC 4380

GTGGTGGTCA TCACCAGAGA GGTTCCCTAT CTCACGGTGG CTGATTTTGT GCGGGACTCT 4440

CTGGGCCAGC ACGGGAAGAG CCCGGACCTG TATGAGAGGC AAGTGTGTCT GCTGCTCTTA 4500

CAGCTGTGCT CTGGCCTGGA GCACCTCAAG CCCTACCACG TCACTCACTG CGATCTTCGT 4560

CTGGAGAACC TGCTGCTCGT CCACTACCAG CCAGGGGGGA CCAGCCAGGG CCTGGGGCCC 4620

GCGGAGGCCA GCCCCACCTC ATCTTGTTCC ACCAGGCTCA TCGTAAGCAA CTTCTCTCAA 4680

GCCAAGCAAA AGAGCCATCT GGTGGACCCC GAGATCCTCC GCGACCAGTC CCGCCTCGCT 4740

CCGGAGATCA TAACAGCCAC CCAGTATAAA AAGTGTGATG AGTTCCAGAC GGGCATCCTC 4800

ATCTATGAGA TGCTGCACCT GCCCAACCCG TTCGATGAGA ACCCGGAGCT GAAGGAGAAA 4860

GAATACACTC GGGCAGACCT GCCTCGTATC CCACTCCGCT CCCCCTATTC CCGGGGCCTG 4920

CAGCAGCTGG CCAGCTGCCT TCTCAACCCC AACCCTTCTG AGCGGATCCT CATTTCAGAC 4980

GCCAAAGGCA TCCTCCAGTG TCTGCTGTGG GGCCCCCGGG AAGATCTCTT CCAGACTCTC 5040

ACCATCTCTC CCAGCCCCGC ACAGAGGAGC GCCCTGCTCC AGAACTGGCT AGACATCAAG 5100

CGAACACTGC TCATGATCAA GTTTGCCGAG AAGTCCCTGG ACAGGGAAGG TGGGGTCAAC 5160

CTGGAGGACT GGCTCTGTGC TCAGTATCTG GCTTTTGCCA CTCCAGATTC CCTCGGCTGT 5220

ATTGTGAAGA CCCTGCAACA CCGCTAG 5247

Domain Profile

S: 1     ltsdkpcceagdavyytasyakdplsnyavkickskekksqsy.....vrqslpvhfniq  55

         ltsdkpcceagdavyytasyakdpl+nyavkicksk+k+sq+y     vrqsl+vhfniq

Q: 1331  LTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYyhslaVRQSLAVHFNIQ  1390

         79**********************************************************

S: 56    qdcGhflaevpsrlla..dpdapekd...................pkpasetepsake..  92

         qdcGhflaevp+rll+  dpdape++                   p+p+seteps+k

Q: 1391  QDCGHFLAEVPNRLLPwdDPDAPEEEedemeeaeeevkgetdgksPEPCSETEPSQKAsq  1450

         *****************9******9999*****************************99*

S: 93    .......rdhvvvitrevphltvadfvrdslashraepelyerrvcllllqlcsGlehlk  145

                r+hvvvitrevp+ltvadfvrdsl +h+++p+lyer+vcllllqlcsGlehlk

Q: 1451  glisrkqRSHVVVITREVPYLTVADFVRDSLGQHGKSPDLYERQVCLLLLQLCSGLEHLK  1510

         ************************************************************

S: 146   eygvihrdlrlenlllvhlqpqagaaqaaapaepaptsaapsaapaattasqegprekql  205

         +y+v+h+dlrlenlllvh+qp +g++q+ +pae +pts++

Q: 1511  PYHVTHCDLRLENLLLVHYQP-GGTSQGLGPAEASPTSSCS-------------------  1550

         *********************.******************9...................

S: 206   trlivsnflkakqksgglvdlqikkdqarlapeivsasqykkfdefqtGiliyellhlpn  265

         trlivsnf++akqks +lvd++i++dq+rlapei++a+qykk+defqtGiliye+lhlpn

Q: 1551  TRLIVSNFSQAKQKS-HLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPN  1609

         9**************.********************************************

S: 266   pfevraelkereyrredlprlpllslysrGlqqlasllleadpikriliseakrvl  321

         pf++++elke+ey+r+dlpr+pl+s+ysrGlqqlas+ll+++p++rilis+ak++l

Q: 1610  PFDENPELKEKEYTRADLPRIPLRSPYSRGLQQLASCLLNPNPSERILISDAKGIL  1665

         ******************************************************98

Domain Sequence
(FASTA)

LTSDKPCCEA GDAVYYTASY AKDPLNNYAV KICKSKAKES QQYYHSLAVR QSLAVHFNIQ 60

QDCGHFLAEV PNRLLPWDDP DAPEEEEDEM EEAEEEVKGE TDGKSPEPCS ETEPSQKASQ 120

GLISRKQRSH VVVITREVPY LTVADFVRDS LGQHGKSPDL YERQVCLLLL QLCSGLEHLK 180

PYHVTHCDLR LENLLLVHYQ PGGTSQGLGP AEASPTSSCS TRLIVSNFSQ AKQKSHLVDP 240

EILRDQSRLA PEIITATQYK KCDEFQTGIL IYEMLHLPNP FDENPELKEK EYTRADLPRI 300

PLRSPYSRGL QQLASCLLNP NPSERILISD AKGIL 335

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0015629	; C:actin cytoskeleton
GO:0005925	; C:focal adhesion
GO:0005524	; F:ATP binding
GO:0004715	; F:non-membrane spanning protein tyrosine kinase activity
GO:0016477	; P:cell migration
GO:0046777	; P:protein autophosphorylation
GO:0034446	; P:substrate adhesion-dependent cell spreading

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR008266	; Tyr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00109	; PROTEIN_KINASE_TYR; 1.

Prints

Created Date

20-Feb-2013