EPS-MUM-00032

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUM-00032

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	78.5	1.6E-21	143	309	167

Status

Reviewed

Ensembl Protein

ENSMUSP00000002298

UniProt Accession

Q149T7; Q810X6; Q9D7H6;

Protein Name

Protein phosphatase 1J

Protein Synonyms/Alias

Protein phosphatase 2C isoform zeta; PP2C-zeta;

Gene Name

Ppm1j

Gene Synonyms/Alias

Ppm1j; Ppp2cz;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000002228	ENSMUSP00000002298	ENSMUST00000002298

Organism

Mus musculus

Functional Description

Protein Length

507

Protein Sequence
(FASTA)

MLNRVRSAVA HLVSSGGTSS QRSKSPDLPN ATSAPPAAQE TPKSSREKPG NQVGAPQKTA 60

ETTVSFSRPT FLQLSPGGLR RADDHAGRAV QSPPDTGRRL PWSTGYAEVI NAGKSRHNED 120

QACCEVVYVE SRRSRSVTGV SREPSHNQGF CFYYWGLFDG HAGGGAAEMA SRLLHRHIRE 180

QLKDLVEILK DPLPPPLCLP STPGTPGAPS PSQLVSPQSC WSPQKEVTHD SLIVGAIENA 240

FHLMDEQMAR ERRGHQVEGG CCALVVLYLL GKMYVANAGD SRAIIVRNGE IIPMSREFTP 300

ETERQRLQLL GFLKPELLGS EFTHLEFPRR VQPKELGQRM LYRDQNMTGW AYKKIEVEDL 360

RFPLVCGEGK KARVMATIGV TRGLGDHNLK VCSSTLSIKP FLSCFPEVRV YDLTQYEHCP 420

DDVLVLGTDG LWDVTNDSEV AATVDRVLSS YEPNDPSRYT ALAQALVLGA RGIPRDRGWR 480

LPNNKLGSGD DISVFVIPLG GPGSSYS 507

Nucleotide Sequence
(FASTA)

ATGCTAAACC GGGTGCGCTC AGCCGTGGCG CACCTGGTGA GCTCGGGTGG CACTTCTTCC 60

CAGCGCTCCA AGTCCCCAGA TCTGCCCAAC GCTACCTCAG CGCCTCCCGC CGCCCAAGAA 120

ACACCTAAGA GTTCCCGGGA GAAGCCTGGG AACCAGGTCG GCGCGCCCCA GAAGACCGCG 180

GAGACTACTG TGAGCTTCTC TCGACCCACC TTTCTGCAGC TGAGCCCCGG AGGGCTGCGG 240

CGCGCCGACG ACCACGCAGG CCGGGCTGTG CAAAGCCCCC CAGACACCGG CCGCCGCCTG 300

CCCTGGAGCA CAGGCTATGC CGAGGTCATC AATGCTGGCA AGAGCAGGCA CAATGAGGAT 360

CAGGCTTGCT GCGAGGTTGT GTATGTGGAA AGTCGGAGGA GCAGGAGCGT TACAGGGGTC 420

TCCAGGGAGC CTAGCCATAA CCAGGGCTTC TGCTTTTACT ACTGGGGCCT GTTTGATGGG 480

CACGCTGGTG GAGGAGCAGC TGAAATGGCC TCCCGGCTCC TGCATCGCCA CATCCGGGAA 540

CAGCTCAAGG ATCTAGTAGA AATACTTAAG GATCCCTTGC CGCCTCCCCT CTGTCTCCCA 600

TCCACTCCTG GAACCCCAGG AGCCCCCAGT CCTTCACAGT TGGTTAGCCC TCAATCCTGC 660

TGGTCTCCAC AGAAGGAAGT GACCCATGAC AGCCTGATAG TAGGAGCCAT TGAGAATGCC 720

TTCCATCTCA TGGATGAGCA GATGGCTCGG GAGCGGCGTG GCCACCAAGT GGAAGGGGGC 780

TGCTGTGCAC TAGTGGTGCT GTACCTGCTA GGCAAGATGT ATGTGGCTAA CGCAGGTGAC 840

AGCAGGGCCA TCATTGTCCG AAATGGGGAG ATCATTCCGA TGTCCCGGGA GTTCACACCA 900

GAGACGGAGC GCCAGCGTCT TCAGCTGCTT GGCTTCCTGA AACCAGAACT GCTGGGCAGT 960

GAGTTCACCC ACCTTGAATT TCCCCGAAGA GTTCAGCCCA AGGAACTAGG GCAGAGGATG 1020

CTGTACAGGG ACCAGAATAT GACTGGCTGG GCCTACAAAA AGATTGAGGT GGAGGATCTC 1080

AGGTTTCCTC TGGTCTGTGG GGAGGGCAAA AAGGCCCGGG TAATGGCTAC CATTGGGGTG 1140

ACACGGGGCT TGGGAGACCA CAACCTTAAG GTCTGCAGCT CTACTCTGTC CATCAAGCCT 1200

TTCCTCTCCT GCTTTCCTGA AGTACGAGTG TATGATCTGA CGCAGTATGA GCACTGTCCA 1260

GATGATGTGC TGGTCCTGGG AACAGATGGC TTGTGGGATG TGACCAATGA CTCTGAGGTA 1320

GCTGCCACTG TGGACAGGGT GCTGTCATCC TATGAGCCCA ATGATCCCAG CAGGTATACA 1380

GCTCTGGCCC AAGCTCTGGT CCTGGGGGCC CGGGGAATCC CCCGGGACCG TGGCTGGCGT 1440

CTCCCAAACA ACAAGCTGGG TTCCGGGGAT GACATCTCGG TCTTCGTCAT CCCCCTGGGC 1500

GGGCCAGGCA GCAGTTACTC CTGA 1524

Domain Profile

S: 28    spekkdr....laffgvyDGhggsevakfcseklheilaeele.................  66

         +p+   +    +++ g +DGh+g  +a+++s  lh+++ e+l+

Q: 143   EPSH--NqgfcFYYWGLFDGHAGGGAAEMASRLLHRHIREQLKdlveilkdplppplclp  200

         3333..0345599***********************************************

S: 67    ........................sseseerkvkkalakaFlstdeelkvleeksldidk  102

                                 ++ +++  +  a+++aF  +de++    e++  + +

Q: 201   stpgtpgapspsqlvspqscwspqKEVTHDSLIVGAIENAFHLMDEQM--ARERRGHQVE  258

         ************8888887776655555566666**************..8888888899

S: 103   sGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsredEleRiee  155

          G++a+v+l+   k+yvan+GdSra++ rng+++++s++++p+   E++R++

Q: 259   GGCCALVVLYLLGKMYVANAGDSRAIIVRNGEIIPMSREFTPET--ERQRLQL  309

         ******************************************98..8999876

Domain Sequence
(FASTA)

EPSHNQGFCF YYWGLFDGHA GGGAAEMASR LLHRHIREQL KDLVEILKDP LPPPLCLPST 60

PGTPGAPSPS QLVSPQSCWS PQKEVTHDSL IVGAIENAFH LMDEQMARER RGHQVEGGCC 120

ALVVLYLLGK MYVANAGDSR AIIVRNGEII PMSREFTPET ERQRLQL 167

Keyword

Complete proteome; Hydrolase; Phosphoprotein; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>