EKS-MUM-00036

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUM-00036

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/YANK	510.9	1.8E-153	94	353	260

Status

Reviewed

Ensembl Protein

ENSMUSP00000016125

UniProt Accession

Q8QZV4; Q9JJG4;

Protein Name

Serine/threonine-protein kinase 32C

Protein Synonyms/Alias

Gene Name

Stk32c

Gene Synonyms/Alias

Stk32c; Pkek; MNCb-1563;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000015981	ENSMUSP00000016125	ENSMUST00000016125
ENSMUSG00000015981	ENSMUSP00000126638	ENSMUST00000165870

Organism

Mus musculus

Functional Description

Protein Length

488

Protein Sequence
(FASTA)

MRSGAERRGS SAAAPPSSPP PGRARPAGSD VSPALPPPAA SQPRARDAGD ARAQPRPLFQ 60

WSKWKKRMSM SSISSGSARR PVFDDKEDVN FDHFQILRAI GKGSFGKVCI VQKRDTEKMY 120

AMKYMNKQQC IERDEVRNVF RELEILQEIE HVFLVNLWYS FQDEEDMFMV VDLLLGGDLR 180

YHLQQNVQFS EDTVRLYICE MALALDYLRS QHIIHRDVKP DNILLDEQGH AHLTDFNIAT 240

IIKDGERATA LAGTKPYMAP EIFHSFVNGG TGYSFEVDWW SVGVMAYELL RGWRPYDIHS 300

SNAVESLVQL FSTVSVQYVP TWSKEMVALL RKLLTVNPEH RFSSLQDMQT APSLAHVLWD 360

DLSEKKVEPG FVPNKGRLHC DPTFELEEMI LESRPLHKKK KRLAKNKSRD SSRDSSQSEN 420

DYLQDCLDAI QQDFVIFNRE KLKRSQELMS EPPPGPETSD MTDSTADSEA EPTALPMCGS 480

ICPSSGSS 488

Nucleotide Sequence
(FASTA)

ATGAGGAGCG GGGCGGAGAG AAGGGGCAGC AGCGCCGCGG CGCCCCCCAG TTCGCCGCCT 60

CCCGGTCGTG CGCGCCCCGC GGGCTCCGAT GTGTCCCCCG CCTTGCCGCC GCCGGCAGCT 120

AGCCAGCCCC GGGCCCGGGA CGCCGGAGAT GCCCGCGCGC AGCCGCGCCC CCTGTTTCAG 180

TGGAGCAAGT GGAAGAAGAG GATGTCTATG TCGTCCATAT CGTCAGGCAG CGCGCGGAGG 240

CCGGTGTTTG ACGACAAGGA GGACGTGAAC TTTGACCACT TCCAGATTCT GAGAGCAATT 300

GGGAAAGGCA GCTTTGGCAA GGTGTGCATC GTGCAGAAGC GGGACACAGA GAAGATGTAC 360

GCCATGAAGT ACATGAACAA GCAGCAATGC ATAGAGCGGG ATGAGGTCCG GAATGTCTTC 420

CGGGAGCTGG AGATCCTACA GGAAATCGAG CATGTCTTCC TGGTGAACCT CTGGTACTCC 480

TTCCAGGATG AGGAGGACAT GTTCATGGTG GTGGATCTGC TTCTGGGGGG AGACCTGCGC 540

TACCACCTAC AGCAGAATGT CCAGTTCTCA GAGGACACAG TGAGGCTGTA CATCTGTGAG 600

ATGGCCCTGG CCCTGGACTA CCTGCGTAGC CAACACATCA TCCACAGAGA TGTCAAGCCT 660

GACAACATCC TCCTGGATGA ACAAGGACAT GCACACCTTA CTGACTTCAA CATTGCCACC 720

ATCATAAAGG ATGGGGAGAG GGCGACAGCT TTAGCTGGGA CCAAACCGTA CATGGCTCCA 780

GAGATCTTCC ACTCTTTCGT CAATGGCGGG ACTGGCTACT CCTTCGAGGT GGACTGGTGG 840

TCGGTGGGGG TGATGGCTTA CGAGCTGCTA CGAGGATGGA GACCCTACGA TATCCACTCG 900

AGCAATGCTG TGGAGTCGCT GGTTCAGCTG TTCAGCACTG TGAGTGTCCA GTACGTGCCC 960

ACCTGGTCCA AGGAGATGGT AGCCCTGCTG CGAAAGCTCC TCACCGTGAA CCCTGAGCAC 1020

CGGTTCTCCA GTCTCCAAGA CATGCAGACA GCCCCATCGC TGGCCCACGT GCTGTGGGAC 1080

GACCTGAGTG AAAAGAAGGT GGAGCCAGGC TTTGTGCCCA ATAAAGGCCG CCTGCACTGT 1140

GATCCCACCT TTGAGCTGGA GGAGATGATC CTTGAGTCGA GGCCTCTGCA CAAGAAGAAA 1200

AAGCGGCTGG CCAAGAATAA GTCTCGGGAC AGCAGCAGAG ACAGTTCCCA GTCGGAGAAT 1260

GACTACCTGC AAGACTGCCT GGATGCCATC CAGCAAGACT TCGTGATTTT TAACAGAGAA 1320

AAGTTGAAGA GGAGCCAGGA ACTCATGAGC GAGCCTCCTC CAGGCCCAGA GACGTCAGAT 1380

ATGACAGATT CCACCGCAGA CAGTGAGGCA GAGCCCACAG CCCTGCCCAT GTGTGGCTCC 1440

ATCTGCCCCT CATCTGGGAG CAGCTAG 1467

Domain Profile

S: 1     fqilraiGkGsfGkvcivqkrdtkklyalkymnkqkcierdevrnvlrelellqelehpf  60

         fqilraiGkGsfGkvcivqkrdt+k+ya+kymnkq+cierdevrnv+rele+lqe+eh+f

Q: 94    FQILRAIGKGSFGKVCIVQKRDTEKMYAMKYMNKQQCIERDEVRNVFRELEILQEIEHVF  153

         9***********************************************************

S: 61    lvnlwysfqdeedlfmvvdlllGGdlryhlqqnvkfsedtvklyicelalaleylqeqki  120

         lvnlwysfqdeed+fmvvdlllGGdlryhlqqnv+fsedtv+lyice+alal+yl++q+i

Q: 154   LVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVQFSEDTVRLYICEMALALDYLRSQHI  213

         ************************************************************

S: 121   ihrdikpdnilldekGhahltdfniatvlkdeeratslaGtkpymapevfasylekeaGy  180

         ihrd+kpdnillde+Ghahltdfniat++kd erat+laGtkpymape+f+s+++ ++Gy

Q: 214   IHRDVKPDNILLDEQGHAHLTDFNIATIIKDGERATALAGTKPYMAPEIFHSFVNGGTGY  273

         ************************************************************

S: 181   sfevdwwslGvvayellrgrrpyeiksstaveeivnlfktesvkypstwskelvallkkl  240

         sfevdwws+Gv+ayellrg+rpy+i+ss+ave++v+lf+t+sv+y++twske+vall+kl

Q: 274   SFEVDWWSVGVMAYELLRGWRPYDIHSSNAVESLVQLFSTVSVQYVPTWSKEMVALLRKL  333

         ************************************************************

S: 241   levdpekrlssledikkapy  260

         l+v+pe+r+ssl+d+++ap+

Q: 334   LTVNPEHRFSSLQDMQTAPS  353

         ****************9986

Domain Sequence
(FASTA)

FQILRAIGKG SFGKVCIVQK RDTEKMYAMK YMNKQQCIER DEVRNVFREL EILQEIEHVF 60

LVNLWYSFQD EEDMFMVVDL LLGGDLRYHL QQNVQFSEDT VRLYICEMAL ALDYLRSQHI 120

IHRDVKPDNI LLDEQGHAHL TDFNIATIIK DGERATALAG TKPYMAPEIF HSFVNGGTGY 180

SFEVDWWSVG VMAYELLRGW RPYDIHSSNA VESLVQLFST VSVQYVPTWS KEMVALLRKL 240

LTVNPEHRFS SLQDMQTAPS 260

Keyword

ATP-binding; Complete proteome; Kinase; Magnesium; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0046872	; F:metal ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

mmu:57740

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013