| Tag | Content |
|---|
| EKPD ID | EPS-MUM-00008 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 149.3 | 1.7E-43 | 27 | 165 | 139 |
|
| Status | Reviewed |
| Ensembl Protein | ENSMUSP00000018792 |
| UniProt Accession | Q9JLY7; Q9D715; |
| Protein Name | Dual specificity protein phosphatase 14 |
| Protein Synonyms/Alias | Mitogen-activated protein kinase phosphatase 6; MAP kinase phosphatase 6; MKP-6; |
| Gene Name | Dusp14 |
| Gene Synonyms/Alias | Dusp14; Mkp6; |
| Ensembl Information | |
| Organism | Mus musculus |
| Functional Description | Involved in the inactivation of MAP kinases.Dephosphorylates ERK, JNK and p38 MAP-kinases. |
| Protein Length | 198 |
Protein Sequence
(FASTA) | | MSSRGHSTLP RTLMAPRMIS EGDIGGIAQI TSSLFLGRAS VASNWHLLQA RGITCVINAT 60 | | IEIPNFNWPQ FEYVKVPLAD IPHAPIRLYF DTVADKIHSV SKKHGATLVH CAAGVSRSAT 120 | | LCIAYLMKFH NLCLLEAYNW VKARRPVIRP NLGFWRQLID YESQLFGKSS VKMVQTPYGI 180 | | IPDVYEKESR HLMPYWGI 198 |
|
Nucleotide Sequence
(FASTA) | | ATGAGCTCCA GAGGTCACAG CACGCTCCCA CGGACTCTCA TGGCCCCTCG GATGATTTCC 60 | | GAGGGAGACA TAGGAGGCAT TGCTCAGATC ACCTCCTCTC TCTTCTTGGG CAGAGCCAGC 120 | | GTGGCCTCCA ACTGGCACCT CCTCCAGGCC CGCGGCATCA CCTGCGTCAT CAATGCCACC 180 | | ATCGAGATCC CCAACTTCAA CTGGCCCCAG TTTGAATATG TTAAAGTGCC TCTGGCTGAC 240 | | ATTCCTCATG CCCCCATTAG ACTGTACTTT GACACTGTGG CCGACAAGAT CCACAGTGTG 300 | | AGCAAGAAGC ACGGGGCTAC CTTGGTGCAC TGTGCGGCAG GCGTGAGCCG CTCGGCCACC 360 | | CTCTGTATTG CGTACCTGAT GAAATTCCAC AATCTGTGCC TGTTGGAGGC ATACAACTGG 420 | | GTGAAAGCCC GGAGGCCTGT CATCAGGCCC AACCTGGGCT TCTGGAGGCA GCTGATAGAC 480 | | TACGAGAGCC AGCTCTTTGG GAAGTCTTCA GTTAAGATGG TACAGACACC CTATGGCATC 540 | | ATCCCAGACG TTTATGAGAA GGAGTCCCGA CACTTGATGC CTTATTGGGG GATTTAG 597 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | + +i+++l+lg + +a + L++ git vina++++ ++ + +y+++p | Q: 27 IAQITSSLFLGRASVASNWHLLQARGITCVINATIEIPNF-------NWPQFEYVKVPLA 79 | 789*******************************999993.......356778******* |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | D ++ + yfd++a+ i+++++k+g++lvHCaaGvsRSatl++aYLmk+++l l +A++ | Q: 80 DIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYN 139 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekkl 147 | +vk++rp i+pn gf++QL+ +e +l | Q: 140 WVKARRPVIRPNLGFWRQLIDYESQL 165 | ***********************998 |
|
Domain Sequence
(FASTA) | | IAQITSSLFL GRASVASNWH LLQARGITCV INATIEIPNF NWPQFEYVKV PLADIPHAPI 60 | | RLYFDTVADK IHSVSKKHGA TLVHCAAGVS RSATLCIAYL MKFHNLCLLE AYNWVKARRP 120 | | VIRPNLGFWR QLIDYESQL 139 |
|
| Keyword | Complete proteome; Hydrolase; Phosphoprotein; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |