EKS-MUM-00517

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUM-00517

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	622.3	9.2E-187	153	534	382

Status

Reviewed

Ensembl Protein

ENSMUSP00000019379

UniProt Accession

Q8R2S1; Q8R1D4;

Protein Name

Ribosomal protein S6 kinase-like 1

Protein Synonyms/Alias

Gene Name

Rps6kl1

Gene Synonyms/Alias

Rps6kl1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000019235	ENSMUSP00000019379	ENSMUST00000019379

Organism

Mus musculus

Functional Description

Protein Length

544

Protein Sequence
(FASTA)

MSLVACECPP GPGLEPEPCS RARSQACMYL EQIRNRVATG TADVTKRDYL VDAATQIHLA 60

LERDVSEDYE AAFNHYQNGV DVLLRGVHVD PNKERREAVK LKITKYLRRA EEIFNCHLQR 120

TLGSGASPNT GFSSLRLRPI RTLSSALEQL KGCRVVGIIK KVQVVQDPAT GGTFIVKSLP 180

RCHMVSRERL TIIPHGVPYM TKLLRYFVSE DSIFLHLEHV QGGTLWSHLL SQDHFQYSGL 240

NSGSVQEKSQ AQLSTRLSLM TPAELTPGHT LRQNRIPMEP PRTSQSLPPA LQLQKEADAE 300

PSSRPSAVFS SDPTEAPCGH SHSQVRRAGQ SSNPAPTQRL HWVREGADRV LGAYGRGRGR 360

NPPSANRASL GSGRAAWSLR EGQVKQWAAE MLLALEALHQ QGVLCRDLNP QNLLLDQAGH 420

IQLTYFGQWS EVEPRCSQEA VDCLYSAPEV GGISELTEAC DWWSYGSLLY ELLTGMALSQ 480

SHPSGFQAHT QLQLPEWLSH PAASLLTELL QFEPQRRLGA GGGGTSRLKS HPFFSTIQWS 540

RLMG 544

Nucleotide Sequence
(FASTA)

ATGAGCCTGG TAGCCTGTGA ATGTCCACCT GGACCAGGCC TGGAGCCAGA GCCCTGTTCA 60

CGAGCACGGT CCCAGGCCTG CATGTACCTG GAACAGATTC GTAACCGGGT AGCTACAGGG 120

ACAGCCGATG TGACCAAACG TGACTACCTG GTAGATGCAG CTACACAGAT CCACCTGGCA 180

CTGGAGCGAG ATGTCAGTGA AGACTACGAG GCTGCCTTCA ACCACTACCA GAATGGTGTG 240

GACGTGCTAC TCCGCGGTGT GCATGTTGAC CCCAACAAGG AGAGGCGTGA AGCTGTGAAG 300

CTGAAAATTA CCAAGTACCT ACGGAGGGCA GAGGAGATCT TCAACTGCCA CCTGCAGCGG 360

ACCCTGGGCA GTGGAGCCAG TCCCAACACG GGCTTCAGCA GCTTGAGGCT CCGGCCCATC 420

CGCACACTGA GCTCTGCTCT GGAGCAGCTG AAGGGATGCA GGGTCGTTGG CATCATCAAG 480

AAGGTGCAGG TGGTTCAGGA CCCGGCAACT GGAGGAACCT TCATCGTGAA GAGCCTCCCC 540

AGGTGTCACA TGGTGAGCCG GGAGCGGCTG ACGATCATCC CACATGGCGT CCCCTACATG 600

ACAAAATTGT TGCGATACTT CGTGAGCGAG GACTCCATCT TCCTGCACCT GGAGCATGTG 660

CAAGGAGGCA CCCTTTGGTC ACATCTACTC TCCCAGGACC ATTTTCAATA CTCTGGGCTT 720

AACTCTGGCT CGGTTCAGGA GAAGTCGCAA GCCCAACTCA GCACCCGCCT CAGCCTCATG 780

ACCCCAGCGG AGCTCACACC AGGCCATACC CTGAGGCAGA ACAGAATCCC AATGGAGCCT 840

CCACGGACTT CCCAGAGCCT ACCCCCAGCC CTCCAGCTTC AGAAAGAGGC CGATGCTGAG 900

CCTTCATCCA GGCCCAGTGC TGTCTTCTCT TCAGACCCCA CAGAGGCCCC GTGTGGCCAC 960

TCGCACAGTC AAGTTAGGCG AGCTGGCCAG AGTTCGAACC CAGCACCCAC GCAGAGGCTC 1020

CACTGGGTAC GAGAAGGGGC TGACCGGGTG CTAGGAGCCT ATGGCCGAGG CAGGGGTCGG 1080

AACCCCCCAT CAGCAAACAG GGCCAGCCTG GGGAGCGGAA GAGCTGCCTG GAGCCTGAGG 1140

GAGGGACAGG TGAAGCAGTG GGCAGCTGAG ATGCTGCTGG CATTAGAGGC GCTGCATCAG 1200

CAGGGGGTGC TGTGCCGGGA CCTCAACCCA CAGAACCTGC TCCTGGACCA GGCAGGTCAC 1260

ATCCAACTCA CGTATTTTGG CCAGTGGTCA GAAGTGGAGC CGCGATGCAG CCAGGAGGCC 1320

GTGGACTGTC TGTACAGTGC TCCAGAGGTT GGGGGCATTT CTGAGCTGAC TGAAGCCTGT 1380

GACTGGTGGA GCTATGGCTC ACTCCTGTAT GAACTGCTCA CAGGAATGGC ACTGTCCCAG 1440

AGCCACCCTT CAGGATTCCA GGCCCACACC CAACTCCAGC TGCCTGAGTG GCTTAGTCAC 1500

CCAGCAGCTT CTCTGCTAAC TGAGCTGCTG CAGTTTGAGC CCCAGCGGCG CCTAGGAGCT 1560

GGAGGTGGTG GCACCAGCAG ACTCAAGTCC CATCCCTTTT TCAGTACTAT CCAGTGGAGC 1620

CGGCTAATGG GGTAG 1635

Domain Profile

S: 1     crvvgilkkvqllvepvtgesfvvkslekeavassdrsiflPtnvPymvkLlryfesEek  60

         crvvgi+kkvq++++p+tg++f+vksl++++++s++r++++P++vPym+kLlryf+sE++

Q: 153   CRVVGIIKKVQVVQDPATGGTFIVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDS  212

         9***********************************************************

S: 61    illlLefvegGtLwsfLldeaesrhadlrdGdtqekvkvqltkrllllvgvdlervvelr  120

         i+l+Le+v+gGtLws+Ll+++++++++l++G++qek+++ql++rl+l+++++l+++++lr

Q: 213   IFLHLEHVQGGTLWSHLLSQDHFQYSGLNSGSVQEKSQAQLSTRLSLMTPAELTPGHTLR  272

         ************************************************************

S: 121   derislekprtesllllvgeeptsrsqreaeeesearvklefssdkskaprGn...rirr  177

         ++ri++e+prt+++l     +p+ ++q+ea++e+++r+++ fssd+++ap+G+   ++rr

Q: 273   QNRIPMEPPRTSQSL-----PPALQLQKEADAEPSSRPSAVFSSDPTEAPCGHshsQVRR  327

         **************9.....****************************************

S: 178   egqnsspssskeiklvsedadkslealsrgldkalqsvdka.lslrravwslpEelikqW  236

         +gq+s+p++++++++v+e+ad++l+a++rg++++++s+++a l+++ra+wsl+E+++kqW

Q: 328   AGQSSNPAPTQRLHWVREGADRVLGAYGRGRGRNPPSANRAsLGSGRAAWSLREGQVKQW  387

         ************************************************************

S: 237   aaelvvaleaLHeegvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysA  296

         aae+++aleaLH++gvl+rDln++n+Lld++Gh++ltYfg+wseve++c++eavd+lysA

Q: 388   AAEMLLALEALHQQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPRCSQEAVDCLYSA  447

         ************************************************************

S: 297   PEvgaiselteasDwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLle  356

         PEvg+iseltea+DwWs+G+lLyelLtG+al+++hPsg+qaht+lqlPe++S++A++Ll+

Q: 448   PEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSHPAASLLT  507

         ************************************************************

S: 357   eLLqfePalRlGaGeagvdelkaHPFF  383

         eLLqfeP++RlGaG++g+++lk+HPFF

Q: 508   ELLQFEPQRRLGAGGGGTSRLKSHPFF  534

         **************************9

Domain Sequence
(FASTA)

CRVVGIIKKV QVVQDPATGG TFIVKSLPRC HMVSRERLTI IPHGVPYMTK LLRYFVSEDS 60

IFLHLEHVQG GTLWSHLLSQ DHFQYSGLNS GSVQEKSQAQ LSTRLSLMTP AELTPGHTLR 120

QNRIPMEPPR TSQSLPPALQ LQKEADAEPS SRPSAVFSSD PTEAPCGHSH SQVRRAGQSS 180

NPAPTQRLHW VREGADRVLG AYGRGRGRNP PSANRASLGS GRAAWSLREG QVKQWAAEML 240

LALEALHQQG VLCRDLNPQN LLLDQAGHIQ LTYFGQWSEV EPRCSQEAVD CLYSAPEVGG 300

ISELTEACDW WSYGSLLYEL LTGMALSQSH PSGFQAHTQL QLPEWLSHPA ASLLTELLQF 360

EPQRRLGAGG GGTSRLKSHP FF 382

Keyword

Alternative splicing; ATP-binding; Complete proteome; Direct protein sequencing; Kinase; Nucleotide-binding; Reference proteome; Ribonucleoprotein; Ribosomal protein; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>