EKS-MUM-00135

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUM-00135

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/ABC1	405.4	4.2E-121	150	453	304

Status

Reviewed

Ensembl Protein

ENSMUSP00000098724

UniProt Accession

Q9D0L4; Q3UKJ2;

Protein Name

Uncharacterized aarF domain-containing protein kinase 1

Protein Synonyms/Alias

Gene Name

Adck1

Gene Synonyms/Alias

Adck1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000021044	ENSMUSP00000098724	ENSMUST00000101165
ENSMUSG00000021044	ENSMUSP00000127254	ENSMUST00000166940

Organism

Mus musculus

Functional Description

The function of this protein is not yet clear. It is notknown if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).

Protein Length

525

Protein Sequence
(FASTA)

MARKALKLAS WTSVALAASG VYLYSNNYLD PNDFGAVRVG RAVATTAVIS YDYLTSLRSV 60

PYGSEEYLQR RSQVHLRSAR RLFELCCANR GTFIKVGQHL GALDYLLPEE YTSTLKVLHS 120

QAPQSSMQEV RQVIREDLGK EIHDLFLSFD DTPLGAASLA QVHKAVLHDG RTVAVKVQHP 180

KVQAQSSKDI LLMEVLVLAV KQLFPDFEFM WLVDEAKKNL PLELDFLNEG RNAEKVAHML 240

RHFDFLKVPQ IHWELSTKRV LLMEFVEGGQ VNDRAYMEKN QIDVNEISCH LGKMYSEMIF 300

VNGFVHCDPH PGNVLVRKRP DTGKAEIVLL DHGLYQVLTE EFRLDYCHLW QSLIWTDMDG 360

LKQYSQRLGA ADLYPLFACM LTARSWDSVK QGIGQAPVSA TEDSEIRNNA ACYLPEISQL 420

LNHVPRQMLL ILKTNDLLRS IETTLGTRSS ASSFLNMSRC CIRALAEHKK RDAGSFFRRT 480

QISFSEAFSL WQINLHELLL RVRALRLACW VSALLGWLTR APHRM 525

Nucleotide Sequence
(FASTA)

ATGGCCAGAA AGGCTCTCAA GCTTGCTTCA TGGACCAGCG TGGCTCTTGC TGCCTCCGGT 60

GTCTACCTCT ACAGTAACAA CTACTTGGAC CCTAATGACT TTGGCGCTGT CAGGGTGGGC 120

AGAGCTGTTG CTACGACAGC TGTCATCAGC TATGACTACC TCACCTCCCT GAGGAGTGTC 180

CCATATGGCT CTGAGGAGTA TTTGCAGCGT CGATCCCAGG TGCACCTCCG CTCTGCCAGG 240

CGTCTCTTTG AGCTCTGCTG TGCCAACCGG GGCACTTTCA TCAAGGTGGG CCAGCACCTG 300

GGGGCGCTGG ACTACCTGCT GCCAGAAGAG TACACCAGCA CACTGAAGGT GTTGCACAGT 360

CAAGCCCCAC AGAGCAGCAT GCAAGAGGTC CGGCAGGTCA TCCGAGAAGA CCTGGGCAAG 420

GAGATCCACG ATTTGTTCCT GAGCTTCGAT GACACCCCTC TTGGGGCAGC CTCCCTGGCC 480

CAGGTCCACA AGGCGGTGTT GCATGATGGT CGGACAGTGG CAGTTAAGGT CCAGCACCCG 540

AAGGTTCAGG CTCAAAGCTC TAAGGACATT CTCCTGATGG AGGTGCTTGT CCTGGCCGTG 600

AAGCAACTTT TCCCAGATTT TGAATTCATG TGGCTGGTGG ATGAAGCGAA GAAGAACCTG 660

CCTCTCGAGT TGGACTTCCT GAATGAAGGG AGGAACGCTG AGAAAGTGGC CCACATGCTC 720

AGGCACTTTG ACTTCCTAAA GGTTCCCCAG ATCCACTGGG AGCTGTCTAC CAAGAGGGTG 780

CTCCTGATGG AATTTGTAGA GGGAGGTCAA GTCAACGACA GGGCCTACAT GGAGAAGAAC 840

CAGATCGATG TGAATGAGAT CTCCTGCCAC CTGGGCAAGA TGTACAGTGA GATGATCTTT 900

GTCAATGGCT TCGTGCACTG TGACCCCCAC CCAGGCAACG TACTGGTACG GAAGCGTCCT 960

GACACGGGCA AGGCTGAGAT TGTCCTCTTA GACCATGGGC TTTACCAGGT GCTCACGGAG 1020

GAGTTCCGCC TGGACTACTG CCATCTGTGG CAGTCTCTGA TCTGGACTGA CATGGACGGG 1080

CTGAAACAGT ACAGCCAGCG CCTGGGAGCT GCAGACCTCT ACCCACTGTT TGCCTGTATG 1140

CTGACAGCCC GGTCCTGGGA CTCAGTCAAA CAGGGCATTG GGCAAGCTCC AGTCTCTGCT 1200

ACTGAGGACT CAGAGATTCG CAATAATGCA GCCTGCTACC TGCCTGAGAT CAGCCAGCTC 1260

CTTAACCATG TGCCTCGCCA GATGCTGCTC ATCCTGAAGA CTAATGATCT ACTCCGTAGC 1320

ATTGAGACCA CCCTGGGCAC GCGCTCCAGT GCCAGTTCCT TCCTCAACAT GTCTCGGTGT 1380

TGTATCAGGG CGCTGGCTGA ACACAAGAAG AGGGATGCCG GCTCTTTCTT CAGAAGGACT 1440

CAGATATCTT TCAGTGAGGC CTTTAGCCTG TGGCAGATCA ACCTTCATGA ACTTCTGCTT 1500

CGAGTGAGGG CCTTGAGGCT AGCTTGCTGG GTCTCAGCTC TCCTGGGCTG GCTGACTCGG 1560

GCTCCACACA GAATGTGA 1578

Domain Profile

S: 1     eekPlaaASlaqvhkArLkdGeeVAVKvqypgvkesidsDlktlelllkvlevlfkdlkl  60

         +++Pl+aASlaqvhkA+L+dG++VAVKvq+p+v++++++D+ ++e+l+ ++++lf+d+++

Q: 150   DDTPLGAASLAQVHKAVLHDGRTVAVKVQHPKVQAQSSKDILLMEVLVLAVKQLFPDFEF  209

         689*********************************************************

S: 61    ewlvdelkkeLaleldferEarnaekfrkllkkfkalkvPkvleelstkrvLtmelvegv  120

         +wlvde+kk+L+leldf++E+rnaek++++l++f++lkvP++++elstkrvL+me+veg

Q: 210   MWLVDEAKKNLPLELDFLNEGRNAEKVAHMLRHFDFLKVPQIHWELSTKRVLLMEFVEGG  269

         ************************************************************

S: 121   pvddleyiessqilrneiaekliklllkeifvdnfvhtDphpgNvlvqksskegklelvL  180

         +v+d  y+e++qi++nei+ +l k+++++ifv++fvh+DphpgNvlv+k++ +gk+e+vL

Q: 270   QVNDRAYMEKNQIDVNEISCHLGKMYSEMIFVNGFVHCDPHPGNVLVRKRPDTGKAEIVL  329

         ************************************************************

S: 181   LDfGlsrelsekfrrlyikllkavvdrDrkkvkkksqrlaeltgeeaklladalvervlt  240

         LD+Gl++ l+e+fr  y++l+++++++D++ +k++sqrl+  + + ++l+a++l++r+++

Q: 330   LDHGLYQVLTEEFRLDYCHLWQSLIWTDMDGLKQYSQRLG--AADLYPLFACMLTARSWD  387

         ****************************************..9*****************

S: 241   lgeafasqarkeveeleklaverlessllkllmevlvklprevllilktidllrgieeaL  300

         +++++++q  ++v ++e+++++++++ +l+++++ l+++pr++llilkt+dllr ie++L

Q: 388   SVKQGIGQ--APVSATEDSEIRNNAACYLPEISQLLNHVPRQMLLILKTNDLLRSIETTL  445

         ********..**************************************************

S: 301   kakldile  308

         +++ ++++

Q: 446   GTRSSASS  453

         *9988765

Domain Sequence
(FASTA)

DDTPLGAASL AQVHKAVLHD GRTVAVKVQH PKVQAQSSKD ILLMEVLVLA VKQLFPDFEF 60

MWLVDEAKKN LPLELDFLNE GRNAEKVAHM LRHFDFLKVP QIHWELSTKR VLLMEFVEGG 120

QVNDRAYMEK NQIDVNEISC HLGKMYSEMI FVNGFVHCDP HPGNVLVRKR PDTGKAEIVL 180

LDHGLYQVLT EEFRLDYCHL WQSLIWTDMD GLKQYSQRLG AADLYPLFAC MLTARSWDSV 240

KQGIGQAPVS ATEDSEIRNN AACYLPEISQ LLNHVPRQML LILKTNDLLR SIETTLGTRS 300

SASS 304

Keyword

Alternative splicing; ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Secreted; Serine/threonine-protein kinase; Signal; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>