EKS-MUM-00145

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUM-00145

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	325.4	4.6E-97	180	396	217

Status

Reviewed

Ensembl Protein

ENSMUSP00000021866

UniProt Accession

Q922Q2; Q3U7D5; Q99LZ1; Q9CU84; Q9CXN9;

Protein Name

Serine/threonine-protein kinase RIO1

Protein Synonyms/Alias

RIO kinase 1;

Gene Name

Riok1

Gene Synonyms/Alias

Riok1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000021428	ENSMUSP00000021866	ENSMUST00000021866

Organism

Mus musculus

Functional Description

Protein Length

567

Protein Sequence
(FASTA)

MDCSLDRMAS VVPGQFDDAD SSDSENKELQ PIHAEDGGVL LKSLQNAAAE VKGDAETDEE 60

DDYDDDDDWY LDDATGKLTK GCTWNGGSNY QANRQTSNYN SAKMSTPIDK SLRKFENKIN 120

LNKLNVTDSV TNKVTVKLRQ KEAESYRIKD KADRATVEQV LDPRTRMILF KLLHKDHISE 180

IHGCISTGKE ANVYYASTPS GESRAIKIYK TSILMFKDRD KYVTGEFRFR RGYCKGNPRK 240

MVRTWAEKEM RNLCRLKTAN IPCPEPIRLR SHVLLMGFIG KDDMPAPLLK NVQLSESKAR 300

ELYLQVIQYM RKMYQDARLV HADLSEFNML YHGGDVYIID VSQSVEHDHP HALEFLRKDC 360

TNVNDFFSKH AVAVMTVREL FDFVTDPSIT ADNMDAYLEK AMEIASQRTK EEKTSQDHVD 420

EEVFKQAYIP RTLNEVKNYE RDVDIMMRLK EEDMALNTQQ DNILYQTVMG LKKDLSGVQK 480

VPALLESEVK EETCFGSDDA GGSECSDTVS EEQEDQAGCR NHIADPDIDK KERKKMVKEA 540

QREKRKNKIP KHVKKRKEKT AKAKKGK 567

Nucleotide Sequence
(FASTA)

ATGGACTGCA GTCTGGACAG GATGGCTTCG GTGGTCCCCG GGCAATTTGA CGACGCGGAT 60

TCCTCAGACA GTGAAAACAA AGAACTGCAG CCAATCCATG CAGAAGATGG CGGCGTTCTA 120

CTTAAAAGCC TCCAGAATGC TGCAGCAGAG GTGAAGGGCG ACGCTGAGAC CGATGAGGAA 180

GACGACTATG ATGATGATGA TGATTGGTAC TTGGACGATG CAACTGGAAA ACTCACCAAG 240

GGTTGTACCT GGAATGGCGG CAGTAACTAT CAGGCAAACC GACAGACTTC TAACTACAAT 300

TCAGCCAAAA TGTCTACTCC AATTGACAAG TCCTTGCGAA AATTTGAAAA TAAAATCAAT 360

CTAAATAAGC TGAATGTTAC TGATTCTGTG ACAAATAAAG TCACCGTAAA ATTGAGACAA 420

AAGGAAGCAG AATCGTATCG AATTAAAGAT AAGGCCGACA GAGCAACCGT AGAACAGGTT 480

TTGGATCCCA GAACAAGGAT GATTTTATTC AAGTTGTTGC ATAAAGACCA CATATCAGAG 540

ATACATGGCT GTATTAGCAC TGGAAAAGAA GCTAATGTAT ACTATGCTAG CACACCCAGT 600

GGAGAGAGCA GAGCAATCAA AATATACAAA ACTTCTATTT TGATGTTCAA AGATCGTGAT 660

AAGTATGTGA CTGGGGAATT CAGGTTCCGG CGTGGCTATT GTAAAGGAAA CCCTAGGAAA 720

ATGGTGAGGA CGTGGGCAGA GAAGGAGATG AGGAATTTGT GCAGGCTAAA AACAGCAAAC 780

ATACCATGTC CAGAACCAAT CAGGCTAAGA AGTCATGTTC TTCTCATGGG CTTCATTGGC 840

AAGGATGACA TGCCAGCCCC ACTTTTGAAA AATGTCCAGC TGTCAGAGTC CAAGGCACGG 900

GAGTTGTACC TGCAGGTCAT TCAGTACATG AGGAAAATGT ATCAGGACGC TAGACTTGTC 960

CACGCGGATC TCAGTGAATT CAACATGCTG TACCATGGTG GAGATGTTTA CATCATTGAT 1020

GTTTCTCAGT CTGTGGAGCA TGACCACCCA CATGCATTGG AGTTCTTGAG AAAAGACTGT 1080

ACCAATGTCA ATGATTTCTT TTCCAAGCAT GCTGTTGCAG TGATGACCGT GCGGGAGCTC 1140

TTCGACTTCG TCACAGATCC CTCCATCACT GCTGACAACA TGGATGCTTA CCTGGAAAAG 1200

GCTATGGAAA TAGCATCCCA GAGGACCAAG GAAGAAAAGA CTAGCCAAGA TCATGTGGAT 1260

GAAGAGGTGT TCAAACAAGC ATATATTCCC AGAACCTTAA ACGAAGTAAA GAATTATGAG 1320

AGAGATGTGG ACATCATGAT GAGGTTAAAG GAAGAAGACA TGGCTTTGAA CACTCAGCAA 1380

GACAACATTC TATACCAGAC TGTCATGGGA TTGAAAAAAG ATTTGTCAGG AGTCCAGAAG 1440

GTCCCCGCGC TCCTAGAAAG TGAAGTTAAG GAAGAGACTT GTTTTGGTTC AGACGATGCT 1500

GGGGGCTCTG AGTGCTCCGA CACAGTCTCT GAAGAGCAGG AAGATCAAGC CGGATGCAGA 1560

AACCATATTG CTGACCCTGA CATTGATAAA AAGGAAAGAA AAAAGATGGT CAAGGAAGCC 1620

CAGAGAGAGA AGAGAAAAAA TAAAATCCCT AAACATGTGA AAAAAAGAAA GGAAAAAACA 1680

GCCAAGGCCA AAAAAGGCAA ATAG 1704

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiyktsllvlknrdkYvdgefrfkksrskanpr  61

         ++ ++i++gke++vy +s+ +ge+raiKiykts+l +k+rdkYv gefrf+++++k npr

Q: 180   EIHGCISTGKEANVYYASTPSGESRAIKIYKTSILMFKDRDKYVTGEFRFRRGYCKGNPR  239

         689*********************************************************

S: 62    klsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklkeeei  121

         k++r+wAeKE+rnl rl+++++p+Pepi l++hvl m +ig+d++pap lk+v+l+e+++

Q: 240   KMVRTWAEKEMRNLCRLKTANIPCPEPIRLRSHVLLMGFIGKDDMPAPLLKNVQLSESKA  299

         ************************************************************

S: 122   kelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveieHpdaleflrrD  181

         +elY +++++++k+y+++rLvHaDlsEfn+l++ +++++iDvsqsve++Hp+aleflr+D

Q: 300   RELYLQVIQYMRKMYQDARLVHADLSEFNMLYHGGDVYIIDVSQSVEHDHPHALEFLRKD  359

         ************************************************************

S: 182   vknvkefFkkklvydvlrerelfelvsasgltkekead  219

         ++nv++fF k++v +v+++relf++v++ ++t+++++

Q: 360   CTNVNDFFSKHAV-AVMTVRELFDFVTDPSITADNMDA  396

         *************.********************9984

Domain Sequence
(FASTA)

EIHGCISTGK EANVYYASTP SGESRAIKIY KTSILMFKDR DKYVTGEFRF RRGYCKGNPR 60

KMVRTWAEKE MRNLCRLKTA NIPCPEPIRL RSHVLLMGFI GKDDMPAPLL KNVQLSESKA 120

RELYLQVIQY MRKMYQDARL VHADLSEFNM LYHGGDVYII DVSQSVEHDH PHALEFLRKD 180

CTNVNDFFSK HAVAVMTVRE LFDFVTDPSI TADNMDA 217

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>