| Tag | Content |
|---|
| EKPD ID | EKS-MUM-00160 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| AGC/RSK | 358.2 | 7.2E-107 | 67 | 328 | 262 |
|
| Status | Reviewed |
| Ensembl Protein | ENSMUSP00000112512 |
| UniProt Accession | Q9Z1M4; |
| Protein Name | Ribosomal protein S6 kinase beta-2 |
| Protein Synonyms/Alias | S6K-beta-2; S6K2; 70 kDa ribosomal protein S6 kinase 2; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; |
| Gene Name | Rps6kb2 |
| Gene Synonyms/Alias | Rps6kb2; |
| Ensembl Information | |
| Organism | Mus musculus |
| Functional Description | Phosphorylates specifically ribosomal protein S6. |
| Protein Length | 392 |
Protein Sequence
(FASTA) | | MAAVFDLDLE TEEGSEGEGE PEFSPADVCP LGELRAAGLE TVGHYEEVEL TESSVNLGPE 60 | | RIGPHCFELL SVLGKGGYGK VFQVRKVQGT NLGKIYAMKV LRKAKIVCSA KDTAHTRAER 120 | | NILESVKHPF IVELAYAFQT GGKLYLILEC LSGGELFTHL EREGIFLEDT ACFYLAEITL 180 | | ALGHLHSHGI IYRDLKPENI MLSSQGHIKL TDFGLCKESI HEGAITHTFC GTIEYMAPEI 240 | | LVRTGHNRAV DWWSLGALMY DMLTGSPPFT AENRKKTMDK IIKGKLVLPP YLTPDARDLA 300 | | KKFLKRNPTQ RIGGGLGDAA DVQRHPFFRH INWDDLLARR VDPPFRPSLQ SEEDVSQFDA 360 | | RFTRQTPVDS PDDTALSESA NQAFLPPQVL SL 392 |
|
Nucleotide Sequence
(FASTA) | | ATGGCGGCCG TATTTGATTT AGACTTGGAG ACCGAGGAAG GGAGCGAGGG CGAGGGCGAA 60 | | CCGGAGTTCA GCCCTGCGGA CGTGTGTCCC CTTGGCGAAT TAAGGGCTGC TGGCCTGGAG 120 | | ACAGTGGGAC ACTATGAAGA AGTAGAGCTG ACAGAGAGCA GCGTGAACCT GGGTCCTGAG 180 | | CGCATCGGGC CCCACTGCTT TGAGCTACTG AGTGTACTGG GCAAGGGGGG CTATGGCAAG 240 | | GTGTTCCAGG TGAGAAAAGT GCAAGGCACC AACTTGGGAA AAATATATGC CATGAAGGTC 300 | | TTAAGGAAGG CCAAGATTGT ATGCAGTGCC AAGGACACAG CCCATACCCG GGCTGAGAGG 360 | | AACATTCTAG AATCTGTGAA GCATCCCTTC ATTGTAGAAC TGGCCTATGC TTTCCAGACA 420 | | GGTGGCAAAC TCTACCTCAT CCTGGAGTGC CTCAGTGGTG GTGAGCTCTT CACACATCTT 480 | | GAGCGAGAAG GCATCTTCCT GGAAGACACA GCCTGCTTCT ACCTGGCAGA GATCACACTA 540 | | GCCCTGGGCC ATCTCCATTC CCACGGCATC ATCTACCGGG ACCTCAAGCC TGAGAACATC 600 | | ATGCTCAGCA GCCAGGGCCA CATCAAACTG ACAGACTTTG GACTTTGCAA GGAGTCCATT 660 | | CATGAGGGTG CTATCACTCA CACCTTCTGT GGCACCATTG AGTACATGGC CCCAGAGATT 720 | | CTAGTGCGCA CTGGTCACAA CCGGGCAGTG GACTGGTGGA GCCTGGGAGC CCTGATGTAC 780 | | GACATGCTCA CTGGATCGCC GCCCTTCACT GCAGAGAACC GGAAGAAAAC TATGGATAAA 840 | | ATCATTAAAG GGAAGCTGGT GCTGCCCCCC TACCTCACCC CGGATGCCCG GGACCTTGCC 900 | | AAAAAGTTTC TGAAGCGGAA CCCCACTCAG CGAATTGGGG GTGGCCTGGG AGATGCTGCT 960 | | GATGTCCAGA GGCACCCCTT TTTCCGGCAC ATCAATTGGG ATGATCTCTT GGCCCGCCGC 1020 | | GTGGACCCTC CCTTCAGGCC AAGTCTGCAA TCAGAAGAGG ATGTGAGCCA GTTTGATGCA 1080 | | CGATTCACAC GGCAGACGCC GGTAGATAGT CCAGATGACA CAGCCCTCAG TGAGAGTGCC 1140 | | AACCAAGCCT TCCTGCCCCC TCAAGTTCTC TCCCTTTGA 1179 |
|
| Domain Profile | S: 1 fellkvlgkGaygkvflvrkvekkdtgklyavKvlkkaelvk..kkkertkeereiLeev 58 | fell+vlgkG+ygkvf+vrkv++++ gk+ya+Kvl+ka++v k++++t++er+iLe+v | Q: 67 FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCsaKDTAHTRAERNILESV 126 | 899*************************************9999**************** |
| S: 59 ehpfivklheafqdekklylvlellkGgeLlerlkkkklfseeeasfilaelvlaleylH 118 | +hpfiv+l +afq+ klyl+le+l+GgeL+++l+++++f e++a+f+lae++lal +lH | Q: 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186 | ************************************************************ |
| S: 119 skgvvyrDLkpeNilldeeghvkltDfglakekiaeneekaysfcgTleyvaPevlkrkg 178 | s+g++yrDLkpeNi+l+++gh+kltDfgl+ke+i +++ +++fcgT+ey+aPe+l r+g | Q: 187 SHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESI-HEGAITHTFCGTIEYMAPEILVRTG 245 | *********************************9.9999999****************** |
| S: 179 ydeavDlwslGvllyemLtGktPftgeerketlarilkgkfslklpaweelseeakdlvk 238 | +++avD+wslG+l+y+mLtG++Pft+e+rk+t+++i kgk l lp + l+++a+dl k | Q: 246 HNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGK--LVLPPY--LTPDARDLAK 301 | ****************************************..9*****..********** |
| S: 239 klLkkdpakRlga...taeeikehkfl 262 | k+Lk++p++R+g +a+++++h+f+ | Q: 302 KFLKRNPTQRIGGglgDAADVQRHPFF 328 | ***********999999********97 |
|
Domain Sequence
(FASTA) | | FELLSVLGKG GYGKVFQVRK VQGTNLGKIY AMKVLRKAKI VCSAKDTAHT RAERNILESV 60 | | KHPFIVELAY AFQTGGKLYL ILECLSGGEL FTHLEREGIF LEDTACFYLA EITLALGHLH 120 | | SHGIIYRDLK PENIMLSSQG HIKLTDFGLC KESIHEGAIT HTFCGTIEYM APEILVRTGH 180 | | NRAVDWWSLG ALMYDMLTGS PPFTAENRKK TMDKIIKGKL VLPPYLTPDA RDLAKKFLKR 240 | | NPTQRIGGGL GDAADVQRHP FF 262 |
|
| Keyword | ATP-binding; Complete proteome; Cytoplasm; Kinase; Nucleotide-binding; Nucleus; Phosphoprotein; Reference proteome; Serine/threonine-protein kinase; Transferase. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |