| Tag | Content |
|---|
| EKPD ID | EPS-MUM-00017 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 55.6 | 1.2E-14 | 74 | 146 | 73 |
|
| Status | Reviewed |
| Ensembl Protein | ENSMUSP00000027826 |
| UniProt Accession | Q6NT99; Q9CW48; |
| Protein Name | Dual specificity protein phosphatase 23 |
| Protein Synonyms/Alias | Low molecular mass dual specificity phosphatase 3; LDP-3; |
| Gene Name | Dusp23 |
| Gene Synonyms/Alias | Dusp23; Ldp3; |
| Ensembl Information | |
| Organism | Mus musculus |
| Functional Description | Protein phosphatase that mediates dephosphorylation ofproteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). |
| Protein Length | 150 |
Protein Sequence
(FASTA) | | MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDQGVRHLV SLTERGPPHS DSCPGLTLHR 60 | | MRIPDFCPPS PEQIDQFVKI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERALAAGD 120 | | AIAEIRRLRP GSIETYEQEK AVFQFYQRTK 150 |
|
Nucleotide Sequence
(FASTA) | | ATGGGCGTGC AACCCCCCAA CTTCTCCTGG GTGCTTCCGG GACGGCTGGC CGGACTGGCG 60 | | TTGCCCCGGC TGCCCGCGCA CTACCAGTTC CTGCTGGACC AGGGTGTGCG GCACCTGGTG 120 | | TCCCTGACGG AGCGCGGACC CCCTCACAGT GACAGCTGTC CCGGCCTCAC GCTGCACCGA 180 | | ATGCGCATCC CTGACTTTTG CCCGCCGTCC CCGGAACAGA TCGACCAATT TGTGAAGATC 240 | | GTGGACGAGG CCAATGCCCG GGGAGAGGCT GTTGGAGTGC ACTGTGCCCT AGGCTTTGGC 300 | | CGCACTGGCA CCATGCTAGC CTGCTACTTG GTGAAGGAGC GGGCTTTGGC CGCAGGAGAT 360 | | GCCATTGCTG AGATCCGGCG CCTGCGACCA GGATCCATTG AGACGTATGA ACAGGAGAAG 420 | | GCCGTCTTCC AGTTCTACCA GCGAACAAAA TGA 453 |
|
| Domain Profile | S: 72 fdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsie 131 | d++++++dea+ +g++v vHCa G++R++t++ +YL+k + l++ dAi +++r rp + | Q: 74 IDQFVKIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERALAAGDAIAEIRRLRPGSI 133 | 58899******************************************************9 |
| S: 132 pnegfleQLlele 144 | ++ ++ + ++ | Q: 134 ETYEQEKAVFQFY 146 | 9999988877775 |
|
Domain Sequence
(FASTA) | | IDQFVKIVDE ANARGEAVGV HCALGFGRTG TMLACYLVKE RALAAGDAIA EIRRLRPGSI 60 | | ETYEQEKAVF QFY 73 |
|
| Keyword | Complete proteome; Cytoplasm; Hydrolase; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |