EKS-MUM-00510

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUM-00510

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKR	290.3	3.5E-86	100	264	165

Status

Reviewed

Ensembl Protein

ENSMUSP00000038139

UniProt Accession

Q5SYL1;

Protein Name

Uncharacterized serine/threonine-protein kinase SgK494

Protein Synonyms/Alias

Sugen kinase 494;

Gene Name

Sgk494

Gene Synonyms/Alias

Sgk494;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000037593	ENSMUSP00000038139	ENSMUST00000046361

Organism

Mus musculus

Functional Description

Protein Length

278

Protein Sequence
(FASTA)

MGAVSCRQGQ HTRVSAPQKG DNIQGHWVQG WKSLWCGMGT IRSGLEELWG LQRHQCLHQE 60

LLQPAPLLLE KPQSEWPVPQ FISLFLPEFP VRPVREQQEL KILGLVAKGS FGTVLKVLDC 120

AQKAVFAVKV VPKVKVLQRD TLRQCKEEVS IQRQINHPFV HSLGDSWQGK QHLFIMCSYC 180

SMDLYSLWST VGWFPEDSIR LFAAELVLVL CYLHDLGIIH RDVKMENILL DERGHLKVTD 240

FGLSRHLSQG ARAYTICGTL QYMGEREAKV GREGDLRM 278

Nucleotide Sequence
(FASTA)

ATGGGAGCAG TAAGCTGTCG GCAGGGACAA CACACCCGGG TGTCTGCTCC TCAGAAGGGT 60

GACAACATCC AGGGTCACTG GGTCCAAGGC TGGAAGAGCC TCTGGTGTGG TATGGGGACC 120

ATCAGGTCAG GTCTGGAAGA ACTATGGGGA CTACAGAGGC ATCAGTGCCT ACATCAGGAG 180

CTGCTCCAGC CAGCCCCACT GCTACTAGAG AAGCCTCAGT CTGAGTGGCC AGTGCCTCAG 240

TTCATCAGCC TCTTTCTACC AGAGTTTCCC GTGAGGCCTG TTAGGGAGCA GCAGGAGCTG 300

AAGATTTTAG GCCTTGTGGC TAAAGGTTCG TTTGGAACTG TCCTGAAAGT GCTAGATTGT 360

GCCCAGAAAG CTGTATTTGC AGTGAAGGTG GTGCCCAAAG TAAAAGTTCT ACAGCGGGAT 420

ACGCTGAGGC AGTGCAAAGA AGAGGTTAGC ATCCAGCGAC AGATCAACCA TCCTTTTGTA 480

CACAGTTTGG GGGACAGCTG GCAGGGGAAA CAACACCTCT TTATTATGTG TAGCTACTGC 540

AGCATGGATC TCTACTCCCT GTGGTCTACT GTTGGTTGGT TTCCAGAGGA TTCTATCCGT 600

CTCTTTGCAG CTGAACTGGT CCTTGTACTG TGCTATCTCC ACGACTTGGG TATCATCCAC 660

CGTGATGTAA AGATGGAGAA TATCCTGCTG GATGAACGAG GCCATCTGAA AGTGACAGAC 720

TTTGGTCTGT CTCGCCACCT ATCCCAGGGA GCACGAGCCT ACACTATCTG CGGCACTCTT 780

CAATACATGG GTGAGAGAGA AGCTAAAGTT GGTAGGGAAG GTGACTTAAG GATGTGA 837

Domain Profile

S: 1     lkierlvakGsfGvvlkvskvldieqk..favkvlkkskviekdavrqvkeeasiqrlig  58

         lki +lvakGsfG+vl   kvld++qk  favkv++k+kv+++d++rq+kee+siqr+i

Q: 100   LKILGLVAKGSFGTVL---KVLDCAQKavFAVKVVPKVKVLQRDTLRQCKEEVSIQRQI-  155

         6899************...99**************************************.

S: 59    shPfiaklidsWqtrkhlfilleyvssgdlfslwskvgslsedairlfaaelalaldflh  118

         +hPf+++l+dsWq+++hlfi+++y+ s+dl+slws+vg+++ed+irlfaael+l+l++lh

Q: 156   NHPFVHSLGDSWQGKQHLFIMCSYC-SMDLYSLWSTVGWFPEDSIRLFAAELVLVLCYLH  214

         *************************.9*********************************

S: 119   dagiiyrdvklenillderghlkltdfGlskklkqGastrticGtlqyma  168

         d+gii+rdvk+enillderghlk+tdfGls++l+qGa+++ticGtlqym

Q: 215   DLGIIHRDVKMENILLDERGHLKVTDFGLSRHLSQGARAYTICGTLQYMG  264

         *************************************************6

Domain Sequence
(FASTA)

LKILGLVAKG SFGTVLKVLD CAQKAVFAVK VVPKVKVLQR DTLRQCKEEV SIQRQINHPF 60

VHSLGDSWQG KQHLFIMCSY CSMDLYSLWS TVGWFPEDSI RLFAAELVLV LCYLHDLGII 120

HRDVKMENIL LDERGHLKVT DFGLSRHLSQ GARAYTICGT LQYMG 165

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>