EPS-MUM-00001

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUM-00001

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	55.5	2.0E-14	80	302	223

Status

Reviewed

Ensembl Protein

ENSMUSP00000051838

UniProt Accession

Q6NVE9; Q3TS53; Q8BVC7;

Protein Name

Protein phosphatase PTC7 homolog

Protein Synonyms/Alias

T-cell activation protein phosphatase 2C; TA-PP2C;

Gene Name

Pptc7

Gene Synonyms/Alias

Pptc7; Tapp2c;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000038582	ENSMUSP00000051838	ENSMUST00000053426
ENSMUSG00000038582	ENSMUSP00000113194	ENSMUST00000119015

Organism

Mus musculus

Functional Description

Protein Length

310

Protein Sequence
(FASTA)

MFSVLSYGRL VARAVLGGLS QTDPRAGGGG GGGGGSSGDY GLVTAGCGFG KDFRKGLLKK 60

GACYGDDACF VARHRSADVL GVADGVGGWR DYGVDPSQFS GTLMRTCERL VKEGRFVPSN 120

PVGILTTSYC ELLQNKVPLL GSSTACIVVL DRSSHRLHTA NLGDSGFLVV RGGEVVHRSD 180

EQQHYFNTPF QLSIAPPEAE GVVLSDSPDA ADSTSFDVQL GDIILTATDG LFDNMPDYMI 240

LQELKKLKNS NYESIQRTAR SIAEQAHELA YDPNYMSPFA QFACDNGLNV RGGKPDDITV 300

LLSIVAEYTD 310

Nucleotide Sequence
(FASTA)

ATGTTCTCGG TCTTGTCGTA TGGACGCCTG GTGGCCCGTG CCGTGCTCGG CGGCCTGTCG 60

CAGACCGACC CCAGGGCGGG CGGCGGCGGC GGCGGCGGTG GTGGCAGCAG CGGCGACTAC 120

GGGTTGGTGA CGGCGGGCTG CGGCTTCGGC AAGGACTTCC GTAAGGGCCT GCTCAAGAAG 180

GGCGCGTGCT ACGGGGACGA CGCGTGTTTC GTGGCCCGCC ACCGCTCGGC CGACGTCCTG 240

GGAGTTGCGG ATGGCGTCGG AGGGTGGAGA GACTATGGAG TGGACCCATC TCAGTTCTCA 300

GGGACTTTAA TGCGAACATG CGAGCGGTTA GTGAAAGAAG GACGCTTTGT CCCCAGCAAT 360

CCTGTTGGGA TTCTCACCAC GAGCTACTGT GAGTTGCTGC AAAACAAAGT TCCTTTGCTG 420

GGTAGCAGCA CAGCCTGCAT CGTGGTGCTG GACAGAAGTA GCCACCGCTT GCACACAGCG 480

AACCTGGGTG ACTCGGGCTT CCTGGTGGTC CGGGGCGGCG AGGTTGTGCA CCGGTCTGAC 540

GAGCAGCAGC ACTACTTCAA CACTCCATTC CAGCTCTCCA TCGCCCCTCC TGAGGCCGAG 600

GGGGTTGTCC TGAGCGACAG CCCAGACGCT GCTGATAGCA CATCTTTCGA TGTCCAGTTA 660

GGAGATATCA TCCTGACAGC AACAGATGGG CTCTTTGACA ACATGCCTGA TTACATGATC 720

CTCCAGGAGC TGAAAAAACT GAAGAATTCA AATTATGAGA GTATACAGCG GACTGCAAGA 780

AGCATTGCTG AGCAAGCGCA TGAGCTGGCC TATGACCCAA ATTATATGTC ACCTTTTGCA 840

CAGTTTGCAT GTGACAATGG ATTAAATGTG AGAGGTGGAA AGCCAGATGA CATCACCGTC 900

CTCCTCTCAA TAGTGGCTGA GTACACGGAC TGA 933

Domain Profile

S: 7     lvvgDvvG....hGleAalimgllrsalrelatagle....paevlerlnealarnleee  58

         l+v+D+vG     G++ + ++g l  + ++l+++g      p  +l+      ++ l+++

Q: 80    LGVADGVGgwrdYGVDPSQFSGTLMRTCERLVKEGRFvpsnPVGILTT---SYCELLQNK  136

         789*****99999*******************9997685564444444...444445555

S: 59    ...erfatavlaeydpstgkleyanaGhpppllvrpdg...gtkfllvstglp..lGilp  110

                ta+++++d s+++l+ an+G++ +l+vr+ +   +  ++ + ++ p  l+i p

Q: 137   vplLGSSTACIVVLDRSSHRLHTANLGDSGFLVVRGGEvvhRSDEQQHYFNTPfqLSIAP  196

         4456999*****************************556665555555566668999988

S: 111   e...........adyeeaelqlepgdllllyTDGvtEardpdgelfgkerllallaeaeg  159

                       +++++++++ gd++l +TDG+++++ +   l    + l+ l+++

Q: 197   PeaegvvlsdspDAADSTSFDVQLGDIILTATDGLFDNMPDYMIL----QELKKLKNSNY  252

         899*******9999*************************555555....44444444445

S: 160   esleelldalveelle....................lgsgeleDDitllv  189

         es +++++++ e+++e                    + +g++ DDit+l+

Q: 253   ESIQRTARSIAEQAHElaydpnymspfaqfacdnglNVRGGKPDDITVLL  302

         779************9********************8889********96

Domain Sequence
(FASTA)

LGVADGVGGW RDYGVDPSQF SGTLMRTCER LVKEGRFVPS NPVGILTTSY CELLQNKVPL 60

LGSSTACIVV LDRSSHRLHT ANLGDSGFLV VRGGEVVHRS DEQQHYFNTP FQLSIAPPEA 120

EGVVLSDSPD AADSTSFDVQ LGDIILTATD GLFDNMPDYM ILQELKKLKN SNYESIQRTA 180

RSIAEQAHEL AYDPNYMSPF AQFACDNGLN VRGGKPDDIT VLL 223

Keyword

Alternative splicing; Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>