EPS-MUM-00030

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUM-00030

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	99.2	8.0E-28	183	475	293

Status

Reviewed

Ensembl Protein

ENSMUSP00000056682

UniProt Accession

Q8BVT6;

Protein Name

Protein phosphatase 2C-like domain-containing protein 1

Protein Synonyms/Alias

Gene Name

Pp2d1

Gene Synonyms/Alias

Pp2d1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMUSG00000044957	ENSMUSP00000056682	ENSMUST00000056198

Organism

Mus musculus

Functional Description

Protein Length

620

Protein Sequence
(FASTA)

MNWELYSSPL RVFWRSKVWD EKTSTFTSDE NLKIGKMVGK RRRPRPKRSI DLEDSTEQLI 60

SGDMVTFPCS VCYRELNKAR NFLHKKHHNA LSMLGFQWMG GRQPKPKLVS LHRECIISNL 120

LRSSTYNEKV LHNVNYAFEF LWKKQVPSYF KLCDKVGETS TYSPNSNHLM IKGIAICSNN 180

NSAWKAEPNC KFTVVNDFGD KANVCFFGLF DSHYGYAAAD LASKEFQVLL LHQLSIQDPS 240

YQMTAEQKQL INSFDTVFRE EYRAREEAFS STYKTFRTSR REYEDTHKAF AKAFWRMDRL 300

LRLGRNETSR VRWSGCSALT CILEGGIKNP HANKDWEKTY QQGSTSLPFQ KTPQIISGVL 360

HLANAGNVQA VLCRNGKGFC LTKEHSTRNT KERRRVLYSE AVISSDDPYG LLDGHIKTTR 420

GLGFHGNLRL KKSIIPAPQT ISVPIDDLCQ FLILATNGLW QVLDKKEVTA LVITLFHAYK 480

ETHVPRPKSK PWPPIGLLSP PDSNIRVLFQ YQPENEDIMS TADGTKGLSD SIYAEAYTHQ 540

GTFSPKVTPY DPCSTKENSS LPTIDSKQEN EKELCIKNFY KGAAEYIGCE LVSAAIEGGS 600

RDSITVMVMF LNGSEYHRLT 620

Nucleotide Sequence
(FASTA)

ATGAATTGGG AACTGTATTC TTCTCCTTTA AGAGTGTTTT GGAGATCAAA AGTGTGGGAT 60

GAGAAAACTT CAACATTTAC TTCTGATGAG AATCTCAAGA TTGGCAAAAT GGTTGGCAAA 120

AGGAGAAGGC CTAGACCAAA GCGCTCCATC GACCTGGAGG ATTCCACTGA GCAGCTGATT 180

TCTGGTGACA TGGTCACATT CCCCTGCTCT GTCTGCTACC GAGAACTGAA CAAAGCTAGG 240

AATTTTCTCC ATAAGAAACA TCACAATGCT CTGAGTATGC TGGGTTTCCA GTGGATGGGA 300

GGGAGGCAAC CAAAGCCCAA ACTGGTCAGT CTTCATAGAG AGTGTATAAT CTCTAACCTT 360

TTGAGATCTT CTACATACAA TGAAAAAGTC CTTCACAATG TGAACTACGC ATTTGAGTTT 420

CTTTGGAAGA AACAAGTTCC ATCATACTTC AAACTTTGTG ATAAGGTTGG CGAGACTTCT 480

ACGTATTCTC CAAACAGCAA CCATCTGATG ATTAAAGGTA TAGCCATCTG TAGCAATAAT 540

AATTCAGCCT GGAAAGCGGA GCCGAACTGT AAATTCACGG TCGTGAACGA TTTTGGTGAT 600

AAGGCCAATG TGTGCTTTTT CGGTTTATTT GATAGCCATT ACGGTTATGC AGCAGCAGAC 660

CTGGCATCAA AGGAGTTTCA GGTTTTACTT CTCCATCAAT TGTCTATACA GGATCCTTCC 720

TACCAAATGA CAGCTGAGCA GAAGCAACTC ATCAATTCCT TTGACACGGT GTTCAGGGAG 780

GAATACAGAG CCAGAGAAGA GGCCTTCTCT TCCACATACA AAACCTTCAG AACTAGTAGA 840

CGGGAGTATG AGGATACACA CAAAGCCTTT GCAAAGGCAT TTTGGAGAAT GGATAGGCTT 900

CTACGGCTTG GAAGGAATGA GACTTCCCGG GTTCGCTGGA GCGGCTGCTC GGCACTCACT 960

TGTATATTAG AGGGTGGGAT TAAGAACCCA CATGCTAATA AAGACTGGGA AAAAACCTAT 1020

CAGCAGGGTT CCACCAGTCT TCCCTTCCAG AAGACTCCAC AGATCATATC TGGAGTACTA 1080

CACCTGGCAA ATGCTGGAAA CGTGCAAGCA GTCTTATGCA GAAATGGAAA AGGGTTTTGC 1140

CTGACCAAGG AACACAGTAC ACGAAACACC AAAGAAAGAA GAAGAGTCCT TTACAGCGAA 1200

GCAGTGATCA GTTCAGATGA CCCCTATGGC CTCCTGGATG GGCACATCAA AACCACCCGG 1260

GGTCTTGGAT TCCATGGAAA CCTCAGACTA AAAAAGTCCA TTATTCCAGC ACCGCAAACA 1320

ATCTCTGTCC CTATAGATGA TCTATGTCAG TTTCTCATCT TAGCCACTAA TGGACTTTGG 1380

CAAGTTTTGG ACAAGAAGGA AGTCACTGCA CTGGTAATCA CCTTGTTTCA TGCATATAAA 1440

GAAACCCATG TTCCTCGCCC TAAAAGCAAA CCCTGGCCAC CTATAGGCCT TCTTTCCCCA 1500

CCAGACAGTA ACATCCGAGT GCTGTTCCAG TACCAGCCTG AAAATGAAGA CATTATGTCA 1560

ACTGCAGATG GGACGAAAGG GCTATCTGAC TCAATATATG CTGAAGCTTA CACTCATCAG 1620

GGTACATTTT CTCCAAAAGT GACCCCTTAT GACCCTTGTA GCACAAAAGA AAATAGCAGC 1680

TTACCCACTA TAGACAGTAA GCAGGAAAAT GAGAAAGAAC TATGTATTAA GAATTTCTAC 1740

AAAGGTGCAG CTGAGTACAT TGGCTGTGAA CTTGTAAGTG CTGCAATAGA AGGGGGTTCC 1800

AGAGACAGCA TCACTGTTAT GGTAATGTTT CTCAATGGGA GCGAGTATCA CAGGCTGACA 1860

TAA 1863

Domain Profile

S: 10    grrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheilaeele...  66

          ++ e + ++t++++f+++ +    + ffg +D h g  +a+ +s++++ +l  +l+

Q: 183   AWKAEPNCKFTVVNDFGDKAN----VCFFGLFDSHYGYAAADLASKEFQVLLLHQLSiqd  238

         466777778889999999765....78*********************************

S: 67    .......................................sseseerkvkkalakaFlstd  87

                                                +s +e ++  ka+akaF ++d

Q: 239   psyqmtaeqkqlinsfdtvfreeyrareeafsstyktfrTSRREYEDTHKAFAKAFWRMD  298

         ***************************9999999999888888888888***********

S: 88    eel...........kvleeksldidksGstavvalik.......................  113

         + l                       sG++a++++++

Q: 299   RLLrlgrnetsrvrW-----------SGCSALTCILEggiknphankdwektyqqgstsl  347

         ***444444444440...........6666666666655555555555555554444444

S: 114   .....ds....klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkd  164

              ++     l+ an+G  +avLcrngk   l+++H++ +++E++R+    + +  +d

Q: 348   pfqktPQiisgVLHLANAGNVQAVLCRNGKGFCLTKEHSTRNTKERRRVLYSEAVISSDD  407

         443335588879****************************************97777777

S: 165   ga.RvlGvLavsRalG...dlylkpyvtpePevtshrltsedefliLasDGlwdvvsnee  220

             + G ++ +R lG    l+lk+ ++p P++ s++++   +fliLa+ Glw+v++++e

Q: 408   PYgLLDGHIKTTRGLGfhgNLRLKKSIIPAPQTISVPIDDLCQFLILATNGLWQVLDKKE  467

         66799**********6433799**************************************

S: 221   avslvrdv  228

         + +lv

Q: 468   VTALVITL  475

         **999765

Domain Sequence
(FASTA)

AWKAEPNCKF TVVNDFGDKA NVCFFGLFDS HYGYAAADLA SKEFQVLLLH QLSIQDPSYQ 60

MTAEQKQLIN SFDTVFREEY RAREEAFSST YKTFRTSRRE YEDTHKAFAK AFWRMDRLLR 120

LGRNETSRVR WSGCSALTCI LEGGIKNPHA NKDWEKTYQQ GSTSLPFQKT PQIISGVLHL 180

ANAGNVQAVL CRNGKGFCLT KEHSTRNTKE RRRVLYSEAV ISSDDPYGLL DGHIKTTRGL 240

GFHGNLRLKK SIIPAPQTIS VPIDDLCQFL ILATNGLWQV LDKKEVTALV ITL 293

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Tarsius syrichta"; ?>Tupaia belangeri"; ?>Vicugna pacos"; ?>