| Tag | Content |
|---|
| EKPD ID | EPS-MUM-00006 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 167.3 | 4.8E-49 | 20 | 158 | 139 |
|
| Status | Reviewed |
| Ensembl Protein | ENSMUSP00000057346 |
| UniProt Accession | Q8VE01; |
| Protein Name | Dual specificity protein phosphatase 18 |
| Protein Synonyms/Alias | |
| Gene Name | Dusp18 |
| Gene Synonyms/Alias | Dusp18; |
| Ensembl Information | |
| Organism | Mus musculus |
| Functional Description | Can dephosphorylate single and diphosphorylatedsynthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine (By similarity). |
| Protein Length | 188 |
Protein Sequence
(FASTA) | | MTSPWSAFPV QIPQPSIRGL SQITKSLFIS NGVAANNKLL LSSNQITTVI NVSVEVANTF 60 | | YEDIQYVQVP VVDAPVARLS NFFDSVADRI HSVEMQKGRT LLHCAAGVSR SAALCLAYLM 120 | | KYHAMSLVDA HTWTKSCRPI IRPNSGFWEQ LIHYELQLFG KNTMQMMDSP MGRIPDIYEK 180 | | ETRLMIPL 188 |
|
Nucleotide Sequence
(FASTA) | | ATGACTTCAC CGTGGAGTGC CTTCCCAGTT CAGATCCCCC AGCCTTCGAT CAGAGGCCTC 60 | | TCGCAGATCA CCAAGAGCCT GTTTATCAGC AATGGTGTGG CTGCCAACAA CAAGCTCCTA 120 | | CTGTCCAGCA ATCAGATCAC CACAGTCATC AACGTCTCAG TAGAGGTAGC AAACACCTTC 180 | | TACGAGGATA TCCAGTATGT GCAGGTGCCT GTGGTCGATG CGCCCGTCGC ACGCCTCTCC 240 | | AATTTCTTCG ATTCCGTTGC CGACCGTATC CATTCGGTGG AGATGCAGAA GGGCCGCACA 300 | | CTGTTGCATT GTGCTGCTGG GGTGAGCCGC TCAGCTGCGC TGTGCCTCGC CTACCTCATG 360 | | AAGTACCATG CCATGTCCCT TGTAGATGCC CACACTTGGA CCAAGTCATG CAGGCCCATC 420 | | ATCCGGCCCA ACAGTGGCTT TTGGGAGCAG CTCATCCATT ACGAGTTGCA GCTCTTTGGC 480 | | AAGAATACAA TGCAGATGAT GGACTCGCCA ATGGGACGGA TCCCAGACAT CTACGAGAAG 540 | | GAGACCCGTT TGATGATCCC ACTGTAA 567 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +++i+ +l++++ a++++ Ls ++it+vin+s++v + ++ ++i+y+++pv | Q: 20 LSQITKSLFISNGVAANNKLLLSSNQITTVINVSVEVAN-------TFYEDIQYVQVPVV 72 | 589************************************.......677*********** |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | D++v l+++fd++a+ i+++++++g++l+HCaaGvsRSa+l+laYLmk++ +sl+dA++ | Q: 73 DAPVARLSNFFDSVADRIHSVEMQKGRTLLHCAAGVSRSAALCLAYLMKYHAMSLVDAHT 132 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekkl 147 | ++k++rp+i+pn+gf+eQL+++e +l | Q: 133 WTKSCRPIIRPNSGFWEQLIHYELQL 158 | ***********************987 |
|
Domain Sequence
(FASTA) | | LSQITKSLFI SNGVAANNKL LLSSNQITTV INVSVEVANT FYEDIQYVQV PVVDAPVARL 60 | | SNFFDSVADR IHSVEMQKGR TLLHCAAGVS RSAALCLAYL MKYHAMSLVD AHTWTKSCRP 120 | | IIRPNSGFWE QLIHYELQL 139 |
|
| Keyword | Complete proteome; Cytoplasm; Hydrolase; Membrane; Mitochondrion; Mitochondrion inner membrane; Nucleus; Protein phosphatase; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | |
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |