EPS-NOL-00018

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00018

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	67.5	1.1E-18	167	247	81

Status

Unreviewed

Ensembl Protein

ENSNLEP00000000365

UniProt Accession

G1QHH8;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000000306	ENSNLEP00000024143	ENSNLET00000032511
ENSNLEG00000000306	ENSNLEP00000000365	ENSNLET00000000390

Organism

Nomascus leucogenys

Functional Description

Protein Length

377

Protein Sequence
(FASTA)

MRNSEMLERG VGGCRVSSGL GSYPGTEGAR LVLSAGLALG GRLLGTHMSQ WHHPRSGWGR 60

RRDFSGRSSA KKKGGNHIPE RWKDYLPVGQ RMPGTRFIAF KVPLQKSFEK KLAPEECFSP 120

LDLFNKIREQ NEELGLIIDL TYTQRYYKPE DLPETIPYLK IFTVGHQVPD DETIFKFKHA 180

VNGFLKENKD NDKLIGVHCT HGLNRTGYLI CRYLIDVEGV RPDDAIELFN RCRGHCLERQ 240

NYIEDLQNGP IRKNWNSSVS RSSGFEDSAH LMQPVHNKPV KQGPRYNLHQ IQGHSAPRHF 300

HTQTQNLQQS VRKFSENPHV YQRRHLPPPG PPGEDCSHRR YSWNVKPNAS RAAEDRRRWY 360

PYNYSGLSYP ACWEWTQ 377

Nucleotide Sequence
(FASTA)

ATGCGCAATA GCGAGATGCT GGAGCGCGGC GTAGGTGGCT GCCGAGTCTC TTCCGGTCTC 60

GGGTCTTATC CTGGCACTGA GGGCGCCCGA CTGGTGCTTT CGGCCGGCTT GGCATTGGGT 120

GGGCGGCTTC TTGGAACCCA CATGAGCCAG TGGCATCATC CCCGCAGTGG CTGGGGCCGG 180

AGACGCGACT TTTCAGGGCG CTCCTCGGCC AAGAAGAAGG GCGGAAACCA CATCCCCGAA 240

AGGTGGAAAG ACTATCTCCC AGTCGGACAG CGGATGCCTG GGACTCGTTT CATTGCTTTC 300

AAAGTTCCTT TGCAAAAGAG TTTTGAAAAG AAACTTGCTC CAGAAGAATG CTTTTCCCCT 360

TTGGATCTTT TTAACAAAAT CCGAGAACAA AATGAAGAAC TTGGACTGAT TATTGATTTA 420

ACATATACTC AACGCTATTA TAAACCAGAA GATTTGCCAG AAACTATTCC TTACTTAAAA 480

ATTTTTACAG TTGGACATCA AGTGCCTGAT GATGAGACTA TTTTTAAATT CAAACACGCT 540

GTTAATGGGT TTTTGAAAGA AAATAAAGAT AATGACAAAC TTATTGGTGT CCATTGTACC 600

CATGGTTTAA ACAGGACTGG CTACCTCATT TGCAGATATT TGATTGATGT AGAAGGCGTG 660

AGGCCAGATG ATGCAATTGA ATTATTCAAT AGGTGCCGGG GACATTGCCT AGAAAGACAA 720

AACTACATCG AAGACCTTCA GAATGGTCCT ATCAGAAAGA ATTGGAATTC CAGTGTATCC 780

AGGTCAAGTG GTTTTGAAGA CTCAGCACAT CTCATGCAAC CAGTCCACAA TAAGCCTGTT 840

AAGCAAGGAC CTAGGTATAA TCTACATCAG ATCCAGGGTC ACTCAGCTCC TCGACATTTC 900

CACACCCAGA CCCAAAATTT GCAACAATCA GTCAGAAAAT TTTCAGAGAA TCCTCATGTT 960

TACCAGAGAC GCCATCTCCC TCCTCCTGGT CCCCCTGGAG AGGACTGTTC ACACAGGAGG 1020

TACTCTTGGA ATGTGAAGCC CAATGCCAGT CGGGCAGCCG AGGATAGAAG AAGGTGGTAT 1080

CCTTACAATT ACTCCGGACT CTCCTATCCA GCCTGTTGGG AATGGACCCA G 1131

Domain Profile

S: 59    pvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsd  118

         +v   d++ ++++ ++++ f++e+k++++ + vHC++G++R+++l++ YL++veg++ +d

Q: 167   QVP--DDETIFKFKHAVNGFLKENKDNDKLIGVHCTHGLNRTGYLICRYLIDVEGVRPDD  224

         333..45689**************************************************

S: 119   AieavkrkrpsiepnegfleQLl  141

         Aie ++r+r+++ ++++++e L

Q: 225   AIELFNRCRGHCLERQNYIEDLQ  247

         *******************9986

Domain Sequence
(FASTA)

QVPDDETIFK FKHAVNGFLK ENKDNDKLIG VHCTHGLNRT GYLICRYLID VEGVRPDDAI 60

ELFNRCRGHC LERQNYIEDL Q 81

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013