EKS-NOL-00187

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00187

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	509.0	3.2E-153	4	284	281

Status

Unreviewed

Ensembl Protein

ENSNLEP00000000743

UniProt Accession

G1QIK0;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000000614	ENSNLEP00000000743	ENSNLET00000000789

Organism

Nomascus leucogenys

Functional Description

Protein Length

623

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFIFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYMLRPLF PGTSEVDEIF KICQVLGTPK KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASNEAIQL MTEMLNWNPK KRPSASQALR HPYFQVGQVL GPSSNHLESK 300

QSLNKQLQPL ESKPSLVEVE PKPLPDIIDQ AVGQPQSETS QQPLQPIQPP QNLRVQQPPK 360

QQSQEKLPQT LFPSIIKNMP TKPNGTLSHK SGRRRWGQTI FKSGDSWEEL EDYDFGASHS 420

KKPSMGVFKE KRKKDSPFRL PEPVPSGSNH STGENKSLPA VISLKSDSEL STASTSKQYY 480

LKQSRYLPGV NPKNVSLIAS GKEINPHTWS NQLFPKSLGP VGAELAFKRS NAGNLGSYAT 540

YNQSGYIPSF LKKEVKSAGQ RIHLAPLNAT ASEYTWNRKT GRGQFSGRTY NPTAKNLNTV 600

NRAQPIPSVH GRTDWVAKYG GHR 623

Nucleotide Sequence
(FASTA)

ATGAACCGAT ACACAACAAT GAGACAATTG GGGGACGGCA CGTATGGGAG TGTGCTTATG 60

GGCAAGAGTA ATGAATCCGG GGAGCTGGTG GCCATCAAAA GGATGAAGAG AAAATTCTAT 120

TCTTGGGATG AATGCATGAA CTTGAGAGAA GTTAAGTCTC TGAAGAAACT TAATCATGCC 180

AATGTTATTA AATTGAAAGA AGTTATCAGA GAAAATGACC ATCTTTATTT TATATTTGAA 240

TATATGAAAG AAAACCTCTA TCAATTAATG AAAGACAGAA ACAAGTTGTT CCCTGAGTCA 300

GTCATCAGAA ATATTATGTA TCAAATATTG CAGGGGCTGG CTTTTATCCA TAAACATGGC 360

TTTTTTCATA GGGACATGAA ACCAGAAAAC TTGCTTTGTA TGGGTCCAGA GCTTGTGAAA 420

ATTGCTGATT TTGGACTTGC AAGAGAATTA AGGTCACAGC CACCATACAC TGATTATGTC 480

TCTACCAGAT GGTATCGTGC CCCTGAAGTT CTACTGAGAT CTTCAGTTTA TAGTTCTCCC 540

ATTGATGTGT GGGCTGTTGG AAGTATCATG GCTGAACTCT ATATGTTAAG GCCACTTTTC 600

CCAGGGACAA GTGAGGTCGA TGAAATCTTT AAAATTTGCC AAGTTTTAGG GACTCCCAAA 660

AAAAGTGACT GGCCAGAAGG ATACCAGCTG GCATCCTCTA TGAACTTCCG TTTTCCCCAG 720

TGTGTTCCTA TAAACTTAAA AACTCTTATT CCCAATGCCA GTAATGAAGC TATTCAGCTC 780

ATGACTGAAA TGTTGAATTG GAATCCAAAG AAACGACCAT CAGCAAGCCA GGCATTGAGA 840

CACCCATATT TTCAAGTTGG TCAGGTATTA GGCCCTTCCT CAAATCATCT GGAATCAAAA 900

CAGTCTTTAA ATAAGCAGCT GCAACCATTA GAATCCAAGC CATCTTTAGT TGAGGTAGAG 960

CCTAAGCCTC TGCCGGATAT AATTGATCAG GCTGTTGGAC AACCCCAGTC AGAAACTAGC 1020

CAGCAGCCAC TGCAGCCCAT TCAGCCGCCA CAGAACCTGC GCGTCCAGCA ACCTCCAAAG 1080

CAACAGAGTC AGGAGAAACT GCCACAAACG CTATTCCCGA GCATCATCAA AAACATGCCA 1140

ACTAAGCCAA ATGGCACACT GAGTCATAAA AGTGGTAGGA GGCGTTGGGG TCAGACTATC 1200

TTCAAGTCTG GAGATAGCTG GGAAGAGTTG GAGGACTATG ATTTCGGAGC CTCCCATTCC 1260

AAGAAGCCAA GCATGGGTGT TTTTAAAGAA AAAAGGAAAA AAGATTCTCC ATTTCGGCTT 1320

CCAGAGCCAG TACCCTCAGG CTCCAACCAC TCGACAGGGG AAAACAAGAG CTTACCTGCT 1380

GTTATTTCCC TAAAATCTGA TTCCGAATTG TCAACTGCTT CAACCTCTAA ACAGTACTAC 1440

TTGAAACAAT CAAGATATCT TCCAGGTGTG AATCCCAAGA ACGTGTCCTT GATAGCCAGT 1500

GGAAAGGAAA TAAACCCTCA CACTTGGAGC AACCAGTTAT TCCCCAAGTC ACTGGGACCT 1560

GTCGGGGCAG AACTTGCTTT CAAAAGGAGC AATGCAGGAA ATCTTGGAAG TTATGCTACT 1620

TACAATCAGT CAGGATATAT TCCTTCCTTT CTCAAAAAAG AAGTGAAGTC AGCTGGCCAG 1680

AGGATCCACT TAGCACCTCT CAATGCAACG GCTTCAGAAT ATACCTGGAA CAGAAAAACT 1740

GGTCGGGGGC AGTTTTCAGG ACGTACTTAC AATCCTACAG CAAAAAACCT AAATACTGTG 1800

AACCGTGCAC AGCCCATTCC CTCAGTGCAC GGAAGGACAG ACTGGGTGGC CAAGTATGGA 1860

GGCCACCGGT AG 1872

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+++e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFIFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtPkk++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYMLRPLFPGTSEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l++++l+++P++r++a+qal++pyf

Q: 241   CVPINLKTLIPNASNEAIQLMTEMLNWNPKKRPSASQALRHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFIFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YMLRPLFPGT SEVDEIFKIC QVLGTPKKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SNEAIQLMTE MLNWNPKKRP SASQALRHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005813	; C:centrosome
GO:0030496	; C:midbody
GO:0072686	; C:mitotic spindle
GO:0005634	; C:nucleus
GO:0001917	; C:photoreceptor inner segment
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0003713	; F:transcription coactivator activity
GO:0046777	; P:protein autophosphorylation

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013