EKS-NOL-00213

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00213

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	364.5	3.2E-109	237	497	261

Status

Unreviewed

Ensembl Protein

ENSNLEP00000001468

UniProt Accession

G1QKM2;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K7

Gene Synonyms/Alias

MAP2K7;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000001225	ENSNLEP00000001468	ENSNLET00000001550

Organism

Nomascus leucogenys

Functional Description

Protein Length

536

Protein Sequence
(FASTA)

MRQGWVQGPG CLQGWPFPCR ARRPVAGRPP RSPLQASVSV SVPSHPPRPP HLCRFLAISA 60

VRCLPLLLVY DLISFLLDES VVSVVIYRGV VFFLPFPHPV IVITLSPAPA PSQRAALQLP 120

LANDGGSRSP SSESSPQHPT PPARPRHMLG LPSTLFTPRS MESIEIDQKL QEIMKQTGYL 180

TIGGQVPPSL WRGEGGGPAR LDPSWGHQWG CGGRAEAPGT LQPSLSSQRY QAEINDLENL 240

GEMGSGTCGQ VWKMRFRKTG HVIAVKQMRR SGNKEENKRI LMDLDVVLKS HDCPYIVQCF 300

GTFITNTDVF IAMELMGTCA EKLKKRMQGP IPERILGKMT VAIVKALYYL KEKHGVIHRD 360

VKPSNILLDE RGQIKLCDFG ISGRLVDSKA KTRSAGCAAY MAPERIDPPD PTKPDYDIRA 420

DVWSLGISLV ELATGQFPYK NCKTDFEVLT KVLQEEPPLL PGHMGFSGDF QSFVKDCLTK 480

DHRKRPKYNK LLEHSFIKRY ETVEVDVASW FKDVMAKTES PRTSSVLSQP HLPFFR 536

Nucleotide Sequence
(FASTA)

ATGAGACAGG GTTGGGTCCA GGGTCCCGGG TGCCTTCAGG GGTGGCCGTT CCCATGCAGA 60

GCTAGGAGGC CGGTGGCAGG CAGGCCCCCG AGGAGTCCCC TCCAGGCGTC TGTGTCTGTG 120

TCAGTTCCAT CCCATCCTCC CCGCCCTCCC CATCTCTGTC GGTTCCTAGC CATCTCTGCA 180

GTTCGGTGCC TCCCCCTCCT CCTCGTTTAT GATTTGATTT CTTTTCTTTT GGACGAATCG 240

GTCGTTTCTG TTGTGATTTA TCGTGGTGTT GTTTTTTTTC TTCCTTTTCC CCATCCAGTT 300

ATTGTGATCA CTCTAAGCCC TGCTCCTGCC CCGTCCCAAC GAGCAGCCCT GCAGCTCCCG 360

CTGGCCAACG ATGGGGGCAG CCGCTCGCCA TCCTCAGAGA GCTCCCCGCA GCACCCCACG 420

CCCCCCGCCC GGCCCCGCCA CATGCTGGGG CTCCCATCAA CCCTGTTCAC ACCCCGCAGC 480

ATGGAGAGCA TTGAGATTGA CCAGAAGCTA CAGGAGATCA TGAAGCAGAC GGGCTACCTG 540

ACCATCGGGG GCCAGGTACC ACCTTCACTG TGGCGGGGAG AGGGAGGAGG CCCAGCCAGG 600

CTGGACCCAT CCTGGGGGCA CCAGTGGGGG TGCGGGGGGC GGGCAGAGGC CCCAGGGACC 660

CTCCAACCCT CCCTCTCCTC CCAGCGCTAC CAGGCAGAAA TCAACGACCT GGAGAACTTG 720

GGCGAGATGG GCAGTGGCAC CTGCGGCCAG GTGTGGAAGA TGCGCTTCCG GAAGACTGGC 780

CACGTCATTG CCGTTAAGCA AATGCGGCGC TCGGGGAACA AGGAGGAGAA CAAGCGCATC 840

CTCATGGACC TGGACGTAGT GCTCAAGAGC CACGACTGCC CCTACATCGT GCAGTGCTTT 900

GGGACGTTCA TCACCAACAC GGACGTCTTC ATCGCCATGG AGCTCATGGG CACCTGCGCT 960

GAAAAGCTCA AGAAGCGGAT GCAGGGCCCC ATCCCCGAGC GCATCCTGGG CAAGATGACA 1020

GTGGCGATTG TGAAGGCGCT GTACTACCTG AAGGAGAAGC ACGGTGTCAT CCACCGCGAC 1080

GTCAAGCCCT CCAACATCCT GCTGGACGAG CGGGGCCAGA TCAAGCTCTG CGACTTCGGC 1140

ATCAGCGGCC GCCTGGTGGA CTCCAAAGCC AAGACGCGGA GCGCCGGCTG CGCCGCCTAC 1200

ATGGCGCCCG AGCGCATTGA CCCCCCAGAC CCCACCAAGC CGGATTATGA CATCCGGGCC 1260

GACGTATGGA GCCTGGGCAT CTCGTTGGTG GAGCTGGCAA CAGGACAGTT TCCCTACAAG 1320

AACTGCAAGA CGGACTTTGA GGTCCTCACC AAAGTCCTAC AGGAAGAGCC CCCGCTTCTG 1380

CCCGGACACA TGGGCTTCTC GGGGGACTTC CAGTCCTTCG TCAAAGACTG CCTTACTAAA 1440

GATCACAGGA AGAGACCAAA GTATAATAAG CTACTTGAAC ACAGCTTCAT CAAGCGATAC 1500

GAGACGGTGG AGGTGGACGT GGCGTCCTGG TTCAAGGACG TCATGGCGAA GACTGAGTCA 1560

CCGCGGACTA GCAGCGTCCT GAGCCAGCCC CACCTGCCCT TCTTCAGGTA G 1611

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le+l+e+G+G++g+V+k++++k+g+++avK++r++ +kee+k+il++l+v+ ks+++pyi

Q: 237   LENLGEMGSGTCGQVWKMRFRKTGHVIAVKQMRRSGNKEENKRILMDLDVVLKSHDCPYI  296

         7899********************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+++G+f++++dv+i+melm  t+ +k+ k++   ++ ipe++lgk++va+vkal ylke

Q: 297   VQCFGTFITNTDVFIAMELMG-TCAEKLKKRM---QGPIPERILGKMTVAIVKALYYLKE  352

         *********************.*****99996...9************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg....  175

         k+ +iHRDvKPsNiL++++G++KlCDFG+sg+lvds Ak++ +G+++YmaPEri++

Q: 353   KHGVIHRDVKPSNILLDERGQIKLCDFGISGRLVDSKAKTRsAGCAAYMAPERIDPpdpt  412

         *******************************************************99999

S: 176   kkkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpee.efseefqe  234

         k++Y++++dvWslG++lvelatg++py+++k+++e+l+++++eepp lp +  fs +fq+

Q: 413   KPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEEPPLLPGHmGFSGDFQS  472

         9************************************************9999*******

S: 235   fvskClkkdekeRpklkellkhafi  259

         fv++Cl+kd+++Rpk+++ll+h+fi

Q: 473   FVKDCLTKDHRKRPKYNKLLEHSFI  497

         ***********************97

Domain Sequence
(FASTA)

LENLGEMGSG TCGQVWKMRF RKTGHVIAVK QMRRSGNKEE NKRILMDLDV VLKSHDCPYI 60

VQCFGTFITN TDVFIAMELM GTCAEKLKKR MQGPIPERIL GKMTVAIVKA LYYLKEKHGV 120

IHRDVKPSNI LLDERGQIKL CDFGISGRLV DSKAKTRSAG CAAYMAPERI DPPDPTKPDY 180

DIRADVWSLG ISLVELATGQ FPYKNCKTDF EVLTKVLQEE PPLLPGHMGF SGDFQSFVKD 240

CLTKDHRKRP KYNKLLEHSF I 261

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004708	; F:MAP kinase kinase activity
GO:0004674	; F:protein serine/threonine kinase activity
GO:0051403	; P:stress-activated MAPK cascade

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013