EKS-NOL-00269

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00269

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/BUB	222.3	6.3E-66	753	951	199

Status

Unreviewed

Ensembl Protein

ENSNLEP00000003290

UniProt Accession

G1QQS2;

Protein Name

Protein Synonyms/Alias

Gene Name

BUB1B

Gene Synonyms/Alias

BUB1B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000002536	ENSNLEP00000003290	ENSNLET00000003456

Organism

Nomascus leucogenys

Functional Description

Protein Length

956

Protein Sequence
(FASTA)

MAAVKKEGGT LSEAMSLEGD EWELSKENVQ PLRQGRIMST LQGALAQESA CNNTLQQQKR 60

AFEYEIRFYT GNDPLDVWDR YISWTEQNYP QGGKESNMST LLERAVEALQ GEKRYYSDPR 120

FLNLWLKLGR LCNEPLDMYS YLHNQGIGVS LAQFYISWAE EYEARENFRK ADAIFQEGIQ 180

QKAEPLERLQ SQHRQFQARV SRQTLLALEK EEEEEVFESS VPQRSTLAEL KSKGKKTARA 240

PIIRIGGALK APSQNRGLQN PFPQQMQSNS RITVFDENAD EASTAELSKP TVQPWIAPPV 300

PRAKENELQA GPWNTGRSLE HRPRGNTASL IAAPAVLPSF TPYVEETAQQ PVMTPCKIEP 360

SINHILSTRK PGKEEGDPLQ RVQSHQQASE EKKEKMMYCK EKIYAGVGEF SFEEIRAEVF 420

RKKLKEQREA ELLTSAEKRA EMQKQIEEME KKLKEIQTTQ QERTGVQQEE TMPTKETTKL 480

QIASESQKIP GMTLSSSVCQ VNSCARETSL AENIWQEQPH SKGPSIPFSI FDEFLLSEKK 540

NKSPPADPPR VSAQRRPLAV LKTSESIISN EDISPDVCDE FTGIEPLSED AIITGFRNVT 600

ICPNPEDTCD FARAARFVST PFHEIMSLKD LPSDPERLLP EEDLDVKTSE DQQTACGTIY 660

SQTLSIKKLS PIIEDSREAT HSSGFSGSSA SVASTSSIKC LQIPEKLELT NETSENPTQS 720

PWCSQYRRQL LKSLPELSAS AELCVEDRPM PKLEIEKEIE LGNEDYCIKQ EYLICEDYKL 780

FWVAPRNSAE LTIIKVSSQP VPWDFYINLK LKERLNEAFD RLCSCYQYQD GCIVWHQYIN 840

CFTLQDLLQH SEYITHEITV LIIYNLLTIV EKLHKAEIVH GDLSPRSLIL RNRIHDPYDC 900

NKNNQALKIV DFSYSVDLRV QLDVFTLSGF RTVQILEGQK ILANCSSPYQ VSVKHA 956

Nucleotide Sequence
(FASTA)

ATGGCGGCGG TGAAGAAGGA AGGGGGTACT CTGAGTGAAG CCATGTCCCT GGAGGGAGAT 60

GAATGGGAAC TGAGTAAAGA AAATGTACAA CCTTTAAGGC AAGGGCGGAT CATGTCCACA 120

CTTCAGGGAG CACTAGCACA AGAATCTGCC TGTAACAATA CTCTTCAGCA GCAGAAACGG 180

GCATTTGAAT ATGAAATTCG ATTTTACACT GGAAATGACC CTCTGGATGT TTGGGATAGG 240

TATATCAGCT GGACAGAGCA GAACTATCCT CAAGGTGGGA AGGAGAGTAA TATGTCAACG 300

TTATTAGAAA GAGCTGTAGA AGCACTACAA GGAGAAAAAC GATATTATAG TGATCCTCGA 360

TTTCTCAATC TCTGGCTTAA ATTAGGGCGT TTATGCAATG AGCCTTTGGA TATGTACAGT 420

TACTTGCACA ACCAAGGGAT TGGTGTTTCA CTTGCTCAGT TCTATATCTC ATGGGCAGAA 480

GAATATGAAG CTAGAGAAAA CTTTAGGAAA GCAGATGCGA TATTTCAGGA AGGGATTCAA 540

CAGAAGGCTG AACCACTAGA AAGACTACAG TCCCAGCACC GACAATTCCA AGCTCGAGTG 600

TCTCGACAAA CTCTGTTGGC ACTTGAGAAA GAAGAAGAGG AGGAAGTTTT TGAGTCTTCT 660

GTACCACAAC GAAGCACACT AGCTGAACTA AAGAGCAAAG GGAAAAAGAC AGCAAGAGCT 720

CCAATCATCC GTATAGGAGG TGCTCTCAAG GCTCCAAGCC AGAACAGAGG ACTCCAAAAT 780

CCATTTCCTC AACAGATGCA AAGTAATAGT AGAATTACTG TTTTTGATGA AAATGCTGAT 840

GAGGCTTCTA CAGCAGAGTT GTCTAAGCCT ACAGTCCAGC CATGGATAGC ACCCCCCGTG 900

CCCAGGGCCA AAGAGAATGA GCTGCAAGCA GGCCCTTGGA ACACAGGCAG GTCCTTGGAA 960

CACAGGCCTC GTGGCAATAC AGCTTCACTG ATAGCTGCAC CCGCTGTGCT TCCCAGTTTT 1020

ACTCCATATG TGGAAGAGAC TGCACAACAG CCAGTTATGA CACCATGTAA AATTGAACCT 1080

AGTATAAACC ACATCCTAAG CACCAGAAAG CCTGGAAAGG AAGAAGGAGA TCCTCTACAA 1140

AGGGTTCAGA GCCATCAGCA AGCATCTGAG GAGAAGAAAG AGAAGATGAT GTATTGTAAG 1200

GAGAAGATTT ATGCAGGAGT GGGGGAATTC TCCTTTGAAG AAATTCGGGC TGAAGTTTTC 1260

CGGAAGAAAT TAAAAGAGCA AAGGGAAGCC GAGCTATTGA CCAGTGCAGA GAAGAGAGCA 1320

GAAATGCAGA AACAGATTGA AGAGATGGAG AAGAAGCTAA AAGAAATCCA AACTACTCAG 1380

CAAGAAAGAA CAGGTGTTCA GCAAGAAGAG ACGATGCCTA CAAAGGAAAC AACTAAACTG 1440

CAAATTGCTT CTGAGTCTCA GAAAATACCA GGAATGACTC TATCCAGTTC TGTTTGTCAA 1500

GTAAACTCTT GTGCCAGAGA AACTTCACTT GCGGAGAACA TTTGGCAGGA ACAACCTCAT 1560

TCTAAAGGTC CCAGTATACC TTTCTCCATT TTTGATGAGT TTCTTCTTTC AGAAAAGAAG 1620

AATAAAAGTC CTCCTGCAGA TCCCCCACGA GTTTCAGCTC AACGAAGACC CCTTGCAGTT 1680

CTCAAAACCT CAGAAAGCAT CATCTCAAAT GAAGACATAT CTCCAGATGT TTGCGATGAA 1740

TTTACAGGAA TTGAACCCTT GAGCGAGGAT GCCATTATCA CAGGCTTCAG AAATGTAACA 1800

ATTTGTCCTA ACCCAGAAGA CACTTGTGAC TTTGCCAGAG CAGCTCGTTT TGTATCCACT 1860

CCTTTTCATG AGATAATGTC CTTGAAGGAT CTCCCTTCTG ATCCTGAGAG ACTGTTACCG 1920

GAAGAGGATC TAGATGTGAA GACCTCTGAG GACCAGCAGA CAGCTTGTGG CACTATCTAT 1980

AGTCAGACTC TCAGCATCAA GAAGCTGAGC CCAATTATTG AAGACAGTCG TGAAGCCACA 2040

CACTCCTCTG GCTTCTCTGG TTCTTCTGCC TCGGTTGCAA GCACCTCCTC CATCAAATGT 2100

CTTCAAATTC CTGAGAAACT AGAACTTACT AATGAGACTT CAGAAAACCC TACTCAGTCA 2160

CCGTGGTGTT CACAGTATCG CAGACAGCTA CTGAAGTCCC TACCAGAGTT AAGTGCCTCT 2220

GCAGAGTTGT GTGTAGAAGA CAGACCAATG CCTAAGTTGG AAATTGAGAA GGAAATTGAA 2280

TTAGGTAACG AGGATTACTG CATTAAACAA GAATACCTAA TATGTGAAGA TTACAAGTTA 2340

TTCTGGGTGG CGCCAAGAAA CTCTGCAGAA TTAACCATAA TAAAGGTATC GTCTCAACCT 2400

GTCCCATGGG ACTTTTATAT CAACCTCAAG TTAAAGGAAC GTTTAAATGA AGCCTTTGAT 2460

CGTTTGTGCA GCTGTTATCA ATATCAAGAT GGCTGTATTG TTTGGCACCA ATATATAAAC 2520

TGCTTCACCC TTCAGGATCT TCTCCAACAC AGTGAATATA TTACCCATGA AATAACAGTG 2580

TTGATTATTT ATAACCTTTT GACAATAGTG GAGAAGCTAC ACAAAGCAGA AATAGTCCAT 2640

GGTGACTTGA GTCCAAGGAG TCTGATTCTC AGAAACAGAA TCCACGATCC CTATGATTGT 2700

AACAAGAACA ATCAAGCTTT GAAGATAGTG GACTTTTCCT ACAGTGTTGA CCTTAGGGTG 2760

CAGCTGGATG TTTTTACCCT CAGCGGCTTT CGGACTGTAC AGATCCTGGA AGGACAAAAG 2820

ATCCTGGCTA ACTGTTCTTC TCCCTACCAG GTAAGTGTAA AACATGCCTG A 2871

Domain Profile

S: 1     leiekeigeGayakvykaeh....dsk........sgelvalKvekpansWefYIclqlk  48

         leiekei+ G++++++k+e+    d+k        s+el+++Kv++++++W+fYI+l+lk

Q: 753   LEIEKEIELGNEDYCIKQEYliceDYKlfwvaprnSAELTIIKVSSQPVPWDFYINLKLK  812

         68******************999988899999999*************************

S: 49    eRlkeeellksiieissallfqdasllvleyasygtlldlinkvkevtnkvmdeelvvll  108

         eRl+e      +++++s++++qd+++++++y++++tl+dl+++++++t     +e++vl+

Q: 813   ERLNEA-----FDRLCSCYQYQDGCIVWHQYINCFTLQDLLQHSEYIT-----HEITVLI  862

         ****87.....*************************************.....*******

S: 109   ivqllkiveklHeveIiHgDlkPdnfllgnrimdkadkdkeekglkliDfgrsiDmkllp  168

         i++ll+iveklH++eI+HgDl+P++++l+nri+d++d++k++++lk++Df++s+D+++++

Q: 863   IYNLLTIVEKLHKAEIVHGDLSPRSLILRNRIHDPYDCNKNNQALKIVDFSYSVDLRVQL  922

         ************************************************************

S: 169   dgtkfkgkaktdafeciemlagkswsYqv  197

         d+++++g+++++++e++++la++s++Yqv

Q: 923   DVFTLSGFRTVQILEGQKILANCSSPYQV  951

         ****************************8

Domain Sequence
(FASTA)

LEIEKEIELG NEDYCIKQEY LICEDYKLFW VAPRNSAELT IIKVSSQPVP WDFYINLKLK 60

ERLNEAFDRL CSCYQYQDGC IVWHQYINCF TLQDLLQHSE YITHEITVLI IYNLLTIVEK 120

LHKAEIVHGD LSPRSLILRN RIHDPYDCNK NNQALKIVDF SYSVDLRVQL DVFTLSGFRT 180

VQILEGQKIL ANCSSPYQV 199

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0000940	; C:condensed chromosome outer kinetochore
GO:0048471	; C:perinuclear region of cytoplasm
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0034501	; P:protein localization to kinetochore

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR013212	; Mad3_BUB1_I.
IPR000719	; Prot_kinase_cat_dom.
IPR015661	; Ser/Thr_kinase_Bub1.

Pfam

PF08311	; Mad3_BUB1_I; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00777

; Mad3_BUB1_I; 1.

Prosites

PS51489

; BUB1_N; 1.

Prints

Created Date

20-Feb-2013