EKS-NOL-00061

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00061

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	366.2	1.0E-109	186	465	280

Status

Unreviewed

Ensembl Protein

ENSNLEP00000003874

UniProt Accession

G1QSF6;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK16

Gene Synonyms/Alias

CDK16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000003184	ENSNLEP00000003874	ENSNLET00000004067

Organism

Nomascus leucogenys

Functional Description

Protein Length

515

Protein Sequence
(FASTA)

MVIKQMLIWD PFPSLSLAHI AMDRMKKIKR QLSMTLRGGR GIDKTNGAPE QIGLDESGGG 60

GGSDPGEAPT RAAPGELRSA RGPLSSAPEI VHEDLKMGSD GESDQASATS SDEVQSPVRV 120

RMRNHPPRKI STEDINKRLS LPADIRLPEG YLEKLTLNSP IFDKPLSRRL RRVSLSEIGF 180

GKLETYIKLD KLGEGTYATV YKGKSKLTDN LVALKEIRLE HEEGAPCTAI REVSLLKDLK 240

HANIVTLHDI IHTEKSLTLV FEYLTRTAVP DDCGNIINMH NVKLFLFQLL RGLAYCHRQK 300

VLHRDLKPQN LLINERGELK LADFGLARAK SIPTKTYSNE VVTLWYRPPD ILLGSTDYST 360

QIDMWGVGCI FYEMATGRPL FPGSTVEEQL HFIFRILGTP TEETWPGILS NEEFKTYNYP 420

KYRAEALLSH APRLDSDGAD LLTKLLQFEG RNRISAEDAM KHPFFFSLGE RIHKLPDTTS 480

IFALKEIQLQ KEASLRSSSM PDSGRPAFRV VDTEF 515

Nucleotide Sequence
(FASTA)

ATGGTGATCA AGCAAATGCT AATATGGGAC CCATTTCCAT CCTTGTCCCT TGCTCATATC 60

GCCATGGATC GGATGAAGAA GATCAAACGG CAGCTGTCAA TGACACTCCG AGGTGGCCGA 120

GGCATAGACA AAACCAATGG TGCCCCTGAG CAGATAGGCC TGGATGAGAG TGGTGGTGGT 180

GGCGGCAGTG ACCCTGGAGA GGCCCCCACA CGTGCTGCTC CTGGGGAACT TCGTTCTGCA 240

CGGGGCCCAC TCAGCTCTGC ACCAGAGATT GTGCACGAGG ACTTGAAGAT GGGGTCTGAT 300

GGGGAGAGTG ACCAGGCTTC AGCCACGTCC TCGGATGAGG TGCAGTCTCC AGTGAGAGTG 360

CGTATGCGCA ACCATCCCCC ACGCAAGATC TCCACTGAGG ACATCAACAA GCGCCTATCG 420

CTACCAGCTG ACATCCGGCT GCCTGAGGGC TACCTGGAGA AGCTGACCCT CAATAGCCCC 480

ATCTTTGACA AGCCCCTCAG CCGCCGCCTC CGTCGTGTCA GCCTATCTGA GATTGGCTTT 540

GGGAAACTGG AGACCTACAT TAAGCTGGAC AAGCTGGGCG AGGGTACCTA TGCCACCGTC 600

TACAAAGGCA AAAGCAAGCT CACAGACAAC CTTGTGGCAC TCAAGGAGAT CAGACTGGAA 660

CATGAAGAGG GGGCACCCTG CACCGCCATC CGGGAAGTGT CCCTGCTCAA GGACCTCAAA 720

CACGCCAACA TCGTTACGCT ACATGACATT ATCCACACGG AGAAGTCCCT CACCCTTGTC 780

TTTGAGTACC TGACAAGGAC CGCAGTACCT GATGACTGTG GGAACATCAT CAACATGCAC 840

AACGTGAAAC TGTTCCTGTT CCAGCTGCTC CGTGGCCTGG CCTACTGCCA CCGGCAGAAG 900

GTGCTACACC GAGACCTCAA GCCCCAGAAC CTGCTCATCA ACGAGAGGGG AGAGCTCAAG 960

CTGGCTGACT TTGGCCTGGC CCGAGCCAAG TCAATCCCAA CAAAGACATA CTCCAATGAG 1020

GTGGTGACGC TGTGGTACCG GCCCCCTGAC ATCCTGCTCG GGTCCACGGA CTACTCCACT 1080

CAGATTGACA TGTGGGGTGT GGGCTGCATC TTCTATGAGA TGGCCACAGG CCGTCCCCTC 1140

TTTCCGGGCT CCACGGTGGA GGAACAGCTA CACTTCATCT TCCGCATCTT AGGAACCCCA 1200

ACTGAGGAGA CGTGGCCAGG CATCCTGTCC AACGAGGAGT TCAAGACATA CAACTACCCC 1260

AAGTACCGAG CCGAGGCCCT TTTGAGCCAC GCACCCCGAC TTGATAGCGA CGGGGCCGAC 1320

CTCCTTACCA AGCTGTTGCA GTTTGAGGGT CGAAATCGGA TCTCCGCAGA GGATGCCATG 1380

AAACATCCAT TCTTCTTCAG TCTGGGGGAG CGGATCCACA AACTTCCTGA CACTACTTCC 1440

ATATTTGCAC TAAAGGAGAT TCAGCTACAA AAGGAGGCCA GCCTTCGGTC TTCGTCGATG 1500

CCTGACTCAG GCAGGCCAGC TTTCCGCGTG GTGGACACCG AGTTTTAA 1548

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 186   YIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  244

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l +    + +++ +  +++++vk +l+qll+glay+H++k

Q: 245   VTLHDIIH-TEKSLTLVFEYLTRT--AVPDDCGN-IINMHNVKLFLFQLLRGLAYCHRQK  300

         ********.99**********984..56677777.9************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 301   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  360

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 361   QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKtYNYP  420

         *******************************************************88***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l++++ dll+kll+++ ++Risa++a++h++f

Q: 421   KYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF  465

         *******************************************98

Domain Sequence
(FASTA)

YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTEK SLTLVFEYLT RTAVPDDCGN IINMHNVKLF LFQLLRGLAY CHRQKVLHRD 120

LKPQNLLINE RGELKLADFG LARAKSIPTK TYSNEVVTLW YRPPDILLGS TDYSTQIDMW 180

GVGCIFYEMA TGRPLFPGST VEEQLHFIFR ILGTPTEETW PGILSNEEFK TYNYPKYRAE 240

ALLSHAPRLD SDGADLLTKL LQFEGRNRIS AEDAMKHPFF 280

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013