EKS-NOL-00234

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00234

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	284.3	7.1E-85	66	320	255

Status

Unreviewed

Ensembl Protein

ENSNLEP00000004403

UniProt Accession

G1QTY3;

Protein Name

Protein Synonyms/Alias

Gene Name

HUNK

Gene Synonyms/Alias

HUNK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000003660	ENSNLEP00000004403	ENSNLET00000004636

Organism

Nomascus leucogenys

Functional Description

Protein Length

714

Protein Sequence
(FASTA)

MPAAAGDGLL GEPAAPGGGG GAEDAARPAA ACEGSFLPAW VSGVPRERLR DFQHHKRVGN 60

YLIGSRKLGE GSFAKVREGL HVLTGEKVAI KVIDKKRAKK DTYVTKNLRR EGQIQQMIRH 120

PNITQLLDIL ETENSYYLVM ELCPGGNLMH KIYEKKRLEE SEARRYIRQL ISAVEHLHRA 180

GVVHRDLKIE NLLLDEDNNI KLIDFGLSNC AGILGYSDPF STQCGSPAYA APELLARKKY 240

GPKIDVWSIG VNMYAMLTGT LPFTVEPFSL RALYQKMVDK EMNPLPTQLS TGAISFLRSL 300

LEPDPVKRPN IQQALANRWL NENYTGKVPC NVTYPNRISL EDLSPSVVLH MTEKLGYKNS 360

DVINTVLSNR ACHILAIYFL LNKKLERYLS GKSDIQDSLC YKTRLYQIEK YRAPKESYEA 420

SLDTWTRDLE FHAVQDKKPK EQEKRGDFLH RPFSKKLDKN LPSHKQPSGS LMTQIQNTKA 480

LLKDRKASKS SFPDKDSFGC RNIFRKTSDS NCVASSSMEF IPVPPPRTPR IVKKPEPHQP 540

GPGSTGIPHK EDPLMLDMVC SFESVERDDH IEVLSPSHHY RVLNSPVSLA RRNSSERTLS 600

PGLPSGSMSP LHTPLHPTLV SFAHEDKNSS PKEEGLCSPP PVSSNGPMQP LGSPNCVKSR 660

GRFPMMGIGQ MLRKRHQSLQ PSADRPLEAS LPPLQPLAPV NLAFDMADGV KTQC 714

Nucleotide Sequence
(FASTA)

ATGCCGGCGG CGGCGGGGGA CGGGCTCCTG GGGGAGCCGG CGGCGCCTGG GGGCGGCGGC 60

GGCGCGGAGG ACGCGGCCAG GCCCGCGGCG GCCTGCGAGG GAAGTTTCCT GCCTGCCTGG 120

GTGAGCGGCG TGCCCCGCGA GCGGCTCCGC GACTTCCAGC ACCACAAGCG CGTGGGCAAC 180

TACCTCATCG GCAGCAGGAA GCTGGGCGAG GGCTCCTTCG CCAAGGTGCG CGAGGGGCTG 240

CACGTGCTGA CCGGGGAGAA GGTGGCCATA AAAGTCATCG ATAAGAAGAG AGCCAAAAAG 300

GACACCTATG TCACCAAAAA CCTGCGGCGA GAGGGTCAGA TCCAGCAGAT GATCCGCCAC 360

CCCAATATCA CTCAGCTCCT TGATATTTTG GAGACGGAAA ACAGCTACTA CCTGGTCATG 420

GAGCTGTGCC CTGGGGGCAA CCTGATGCAC AAGATCTATG AGAAGAAGCG GCTGGAGGAG 480

TCTGAAGCCC GCAGATACAT CCGGCAGCTC ATCTCCGCCG TAGAGCACCT GCACCGGGCT 540

GGAGTGGTCC ACAGAGACTT GAAGATAGAG AATTTGCTAC TAGATGAAGA CAATAATATC 600

AAGCTGATTG ACTTTGGTTT GAGCAACTGC GCAGGGATCC TGGGTTACTC GGATCCGTTC 660

AGCACACAGT GTGGCAGCCC TGCCTATGCT GCACCTGAAC TGCTTGCCAG GAAGAAATAC 720

GGCCCCAAAA TCGATGTCTG GTCCATAGGT GTGAACATGT ATGCCATGTT GACCGGGACG 780

CTGCCTTTCA CGGTGGAGCC TTTCAGCCTG AGGGCTTTGT ACCAGAAGAT GGTGGACAAA 840

GAAATGAACC CCCTCCCCAC TCAGCTCTCC ACAGGTGCCA TCAGTTTCCT GCGCTCTCTC 900

CTGGAACCGG ATCCTGTGAA GAGGCCAAAT ATTCAGCAGG CACTGGCGAA TCGCTGGCTT 960

AATGAGAATT ACACGGGCAA AGTGCCCTGT AATGTCACCT ATCCCAACAG GATTTCTCTG 1020

GAAGACCTGA GCCCGAGCGT CGTGCTGCAC ATGACCGAGA AGCTGGGTTA CAAGAACAGC 1080

GACGTGATCA ACACCGTGCT CTCCAACCGC GCCTGCCACA TCCTGGCCAT CTACTTCCTC 1140

TTAAACAAGA AACTGGAGCG CTATTTGTCA GGGAAATCTG ACATCCAGGA CAGCCTCTGC 1200

TACAAGACCC GGCTTTACCA GATAGAAAAG TACAGGGCCC CCAAGGAGTC CTATGAGGCC 1260

TCTCTGGACA CCTGGACAAG AGATCTTGAA TTCCATGCCG TGCAGGATAA AAAGCCCAAA 1320

GAACAAGAAA AAAGAGGGGA TTTTCTTCAT CGACCATTCT CTAAGAAGTT GGACAAGAAC 1380

CTTCCCTCGC ACAAACAGCC CTCAGGCTCG CTCATGACAC AGATTCAGAA CACCAAAGCC 1440

CTCCTGAAGG ACCGGAAGGC CTCCAAGTCC AGCTTCCCCG ACAAAGATTC CTTTGGCTGC 1500

CGCAATATTT TCCGCAAAAC CTCGGATTCC AATTGTGTGG CTTCTTCTTC CATGGAGTTC 1560

ATCCCTGTGC CACCTCCCAG GACCCCGAGG ATTGTGAAGA AACCGGAGCC CCATCAGCCA 1620

GGGCCCGGAA GCACTGGCAT CCCCCACAAG GAAGACCCCC TGATGCTGGA CATGGTGTGC 1680

TCCTTCGAGT CTGTGGAGCG CGACGACCAC ATAGAAGTGC TGTCTCCCTC TCATCACTAC 1740

AGGGTTCTGA ACTCCCCGGT CAGCTTGGCT CGCAGAAATT CCAGCGAGAG GACGCTGTCC 1800

CCGGGTCTGC CATCTGGAAG CATGTCGCCT CTCCATACTC CTTTGCATCC AACTCTGGTC 1860

TCTTTTGCTC ATGAAGATAA GAACAGCTCC CCAAAAGAGG AGGGCCTGTG TTCCCCACCT 1920

CCGGTTTCCA GCAATGGCCC CATGCAGCCT CTGGGGAGCC CGAATTGTGT GAAAAGCCGA 1980

GGCCGGTTCC CCATGATGGG CATCGGACAG ATGTTGAGGA AGCGCCATCA GAGTCTGCAG 2040

CCATCTGCAG ATAGGCCCCT GGAGGCCAGC CTGCCCCCAC TGCAGCCCCT AGCCCCCGTG 2100

AACCTTGCCT TTGACATGGC CGATGGGGTC AAGACCCAGT GCTAA 2145

Domain Profile

S: 5     ktlGegsfgkVklakhketkekvavKiikkkkl..seeslekikrEieilkklkhpniik  62

         ++lGegsf+kV++  h +t+ekva+K+i+kk++  ++  +++++rE +i+++++hpni++

Q: 66    RKLGEGSFAKVREGLHVLTGEKVAIKVIDKKRAkkDTYVTKNLRREGQIQQMIRHPNITQ  125

         68****************************98844556688*******************

S: 63    llevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgivHr  122

         ll+++et++++ylv+e++ gg+L+++i ek+rl+e+ear++++ql+sav++lh+ g+vHr

Q: 126   LLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQLISAVEHLHRAGVVHR  185

         ************************************************************

S: 123   DlKpeNllldkkenikiaDFGlan...lfkegklletfcGsppYaaPellkgkkYegpkv  179

         DlK eNllld+++nik++DFGl+n   ++ +++ ++t+cGsp+YaaPell++kkY gpk+

Q: 186   DLKIENLLLDEDNNIKLIDFGLSNcagILGYSDPFSTQCGSPAYAAPELLARKKY-GPKI  244

         ************************77777888***********************.****

S: 180   DvWslGvvLyalvtgklPfdee..nlkellekilkgkl.eipkklskelesLlrklLvvd  236

         DvWs+Gv +ya++tg+lPf+ e  +l++l++k+ ++++  +p++ls+ ++s+lr+lL+ d

Q: 245   DVWSIGVNMYAMLTGTLPFTVEpfSLRALYQKMVDKEMnPLPTQLSTGAISFLRSLLEPD  304

         ********************998999********9999789*******************

S: 237   pekRatieeilkhewl  252

         p kR++i++ l+++wl

Q: 305   PVKRPNIQQALANRWL  320

         ***************7

Domain Sequence
(FASTA)

RKLGEGSFAK VREGLHVLTG EKVAIKVIDK KRAKKDTYVT KNLRREGQIQ QMIRHPNITQ 60

LLDILETENS YYLVMELCPG GNLMHKIYEK KRLEESEARR YIRQLISAVE HLHRAGVVHR 120

DLKIENLLLD EDNNIKLIDF GLSNCAGILG YSDPFSTQCG SPAYAAPELL ARKKYGPKID 180

VWSIGVNMYA MLTGTLPFTV EPFSLRALYQ KMVDKEMNPL PTQLSTGAIS FLRSLLEPDP 240

VKRPNIQQAL ANRWL 255

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013