EKS-NOL-00151

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00151

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TLK	624.4	1.9E-188	263	542	280

Status

Unreviewed

Ensembl Protein

ENSNLEP00000005640

UniProt Accession

G1QXG6;

Protein Name

Protein Synonyms/Alias

Gene Name

TLK2

Gene Synonyms/Alias

TLK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000004645	ENSNLEP00000005640	ENSNLET00000005932
ENSNLEG00000004645	ENSNLEP00000005637	ENSNLET00000005929

Organism

Nomascus leucogenys

Functional Description

Protein Length

573

Protein Sequence
(FASTA)

AQQNSPSSTG SGNTEHSCSS QKQISIQHRQ TQSDLTIEKI SALENSKNSD LEKKEGRIDD 60

LLRANCDLRR QIDEQQKMLE KYKERLNRCV TMSKKLLIEK SKQEKMACRD KSMQDRLRLG 120

HFTTVRHGAS FTEQWTDGYA FQNLIKQQER INSQREEIER QRKMLAKRKP PAMGQAPPAT 180

NEQKQRKSKT NGAENETLTL AEYHEQEEIF KLRLGHLKKE EAEIQAELER LERVRNLHIR 240

ELKRIHNEDN SQFKDHPTLN DRYLLLHLLG RGGFSEVYKA FDLTEQRYVA VKIHQLNKNW 300

RDEKKENYHK HACREYRIHK ELDHPRIVKL YDYFSLDTDS FCTVLEYCEG NDLDFYLKQH 360

KLMSEKEARS IIMQIVNALK YLNEIKPPII HYDLKPGNIL LVNGTACGEI KITDFGLSKI 420

MDDDSYNSVD GMELTSQGAG TYWYLPPECF VVGKEPPKIS NKVDVWSVGV IFYQCLYGRK 480

PFGHNQSQQD ILQENTILKA TEVQFPPKPV VTPEAKAFIR RCLAYRKEDR IDVQQLACDP 540

YLLPHIRKSV STSSPAGAAI ASTSGASNNS SSN 573

Nucleotide Sequence
(FASTA)

GCTCAGCAAA ACAGTCCCTC ATCTACGGGA TCTGGCAACA CAGAGCATTC CTGCAGCTCC 60

CAAAAACAGA TCTCCATCCA GCACAGACAG ACCCAGTCGG ACCTCACAAT AGAAAAAATA 120

TCTGCACTAG AAAACAGTAA GAATTCTGAC TTAGAGAAGA AGGAGGGAAG AATAGATGAT 180

TTATTAAGAG CCAACTGTGA TTTGAGACGG CAGATTGATG AACAGCAAAA GATGCTAGAG 240

AAATACAAGG AACGATTAAA TAGATGTGTG ACAATGAGCA AGAAACTCCT TATAGAAAAG 300

TCAAAACAAG AGAAGATGGC ATGTAGAGAT AAGAGCATGC AAGACCGCTT GAGACTGGGC 360

CACTTTACTA CTGTCCGACA CGGAGCCTCA TTTACTGAAC AGTGGACAGA TGGTTATGCT 420

TTTCAGAATC TTATCAAGCA ACAGGAAAGG ATAAATTCAC AGAGGGAAGA GATAGAAAGA 480

CAACGGAAAA TGTTAGCAAA GCGGAAACCT CCTGCCATGG GTCAGGCCCC TCCTGCAACC 540

AATGAGCAGA AACAGCGGAA AAGCAAGACC AATGGAGCTG AAAATGAAAC GTTAACGTTA 600

GCAGAATACC ATGAACAAGA AGAAATCTTC AAACTCAGAT TAGGTCATCT TAAAAAGGAG 660

GAAGCAGAGA TCCAGGCAGA GCTGGAGAGG CTAGAAAGGG TTAGAAATCT ACATATCAGG 720

GAACTAAAAA GGATACATAA TGAAGATAAT TCACAATTTA AAGATCATCC AACGCTAAAT 780

GACAGATATT TGTTGTTACA TCTTTTGGGT AGAGGAGGTT TCAGTGAAGT TTACAAGGCA 840

TTTGATTTAA CAGAGCAAAG ATACGTAGCT GTGAAAATTC ACCAGTTAAA TAAAAACTGG 900

AGAGATGAGA AAAAGGAGAA TTACCACAAG CATGCATGTA GGGAATACCG GATTCATAAA 960

GAACTGGATC ATCCCAGAAT AGTTAAGCTG TATGATTACT TTTCACTGGA TACTGACTCG 1020

TTTTGTACAG TATTAGAATA CTGTGAGGGA AATGATCTGG ACTTCTACCT GAAACAGCAC 1080

AAATTAATGT CGGAGAAAGA GGCCCGGTCC ATTATCATGC AGATTGTGAA TGCTTTAAAG 1140

TACTTAAATG AAATAAAACC TCCCATCATA CACTATGACC TCAAACCAGG TAATATTCTT 1200

TTAGTAAATG GTACAGCGTG TGGAGAGATA AAAATTACAG ATTTTGGTCT TTCGAAGATC 1260

ATGGATGATG ATAGCTACAA TTCAGTGGAT GGCATGGAGC TAACATCACA AGGTGCTGGT 1320

ACTTATTGGT ATTTACCACC AGAGTGTTTT GTGGTTGGGA AAGAACCACC AAAGATCTCA 1380

AATAAAGTTG ATGTGTGGTC GGTGGGTGTG ATCTTCTATC AGTGTCTTTA TGGAAGGAAG 1440

CCTTTTGGCC ATAACCAGTC TCAGCAAGAC ATCCTACAAG AGAATACGAT TCTTAAAGCT 1500

ACTGAAGTAC AGTTCCCGCC AAAGCCAGTA GTAACACCTG AAGCAAAGGC GTTTATTCGA 1560

CGATGCTTGG CCTACCGAAA GGAGGACCGC ATTGATGTCC AGCAGCTGGC CTGTGATCCC 1620

TACTTGTTGC CTCACATCCG AAAGTCAGTC TCTACGAGTA GCCCTGCTGG AGCTGCTATT 1680

GCATCAACCT CTGGGGCGTC CAATAACAGT TCTTCTAATT GA 1722

Domain Profile

S: 1     ylllkllgkggfsevykafdlkeqryvavkihqlnkdwkdekkenyvkhalreyrihkel  60

         ylll+llg+ggfsevykafdl+eqryvavkihqlnk+w+dekkeny+kha+reyrihkel

Q: 263   YLLLHLLGRGGFSEVYKAFDLTEQRYVAVKIHQLNKNWRDEKKENYHKHACREYRIHKEL  322

         9***********************************************************

S: 61    dhprivklydllsldtdsfctvleyvegndldfylkqhkllsekearsiimqivsalkyl  120

         dhprivklyd++sldtdsfctvley+egndldfylkqhkl+sekearsiimqiv+alkyl

Q: 323   DHPRIVKLYDYFSLDTDSFCTVLEYCEGNDLDFYLKQHKLMSEKEARSIIMQIVNALKYL  382

         ************************************************************

S: 121   neikppiihydlkpgnillvegtacgeikitdfglskimdddsydsddgleltsqgagty  180

         neikppiihydlkpgnillv+gtacgeikitdfglskimdddsy+s+dg+eltsqgagty

Q: 383   NEIKPPIIHYDLKPGNILLVNGTACGEIKITDFGLSKIMDDDSYNSVDGMELTSQGAGTY  442

         ************************************************************

S: 181   wylppecfvvgkeppkisnkvdvwsvgvifyqclygkkpfghnqsqqdileentilkate  240

         wylppecfvvgkeppkisnkvdvwsvgvifyqclyg+kpfghnqsqqdil+entilkate

Q: 443   WYLPPECFVVGKEPPKISNKVDVWSVGVIFYQCLYGRKPFGHNQSQQDILQENTILKATE  502

         ************************************************************

S: 241   vqfpskpvvsseakafirrclayrkedridvqqlakdeyl  280

         vqfp+kpvv++eakafirrclayrkedridvqqla+d+yl

Q: 503   VQFPPKPVVTPEAKAFIRRCLAYRKEDRIDVQQLACDPYL  542

         **************************************97

Domain Sequence
(FASTA)

YLLLHLLGRG GFSEVYKAFD LTEQRYVAVK IHQLNKNWRD EKKENYHKHA CREYRIHKEL 60

DHPRIVKLYD YFSLDTDSFC TVLEYCEGND LDFYLKQHKL MSEKEARSII MQIVNALKYL 120

NEIKPPIIHY DLKPGNILLV NGTACGEIKI TDFGLSKIMD DDSYNSVDGM ELTSQGAGTY 180

WYLPPECFVV GKEPPKISNK VDVWSVGVIF YQCLYGRKPF GHNQSQQDIL QENTILKATE 240

VQFPPKPVVT PEAKAFIRRC LAYRKEDRID VQQLACDPYL 280

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pongo abelii"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013