EKS-NOL-00086

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00086

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	434.4	3.0E-130	2295	2618	324

Status

Unreviewed

Ensembl Protein

ENSNLEP00000005837

UniProt Accession

G1QY16;

Protein Name

Protein Synonyms/Alias

Gene Name

ATR

Gene Synonyms/Alias

ATR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000004792	ENSNLEP00000005837	ENSNLET00000006145

Organism

Nomascus leucogenys

Functional Description

Protein Length

2643

Protein Sequence
(FASTA)

MGEHGLELAS MIPALRELGS ATPEEYNTVV QKPRQILCQF IDRILTDVNV VAVELVKKTD 60

SQPTSVMLLD FIQHIMKSSP LMFVNVNGSH EAKGSCIEFS NWIITRLLRI AATPSCHLLH 120

KKICEVICSL LFLFKSKSPA IFGVLTKELL QLFEDLVYLH RRNVMGHAVE WPVLMSRFLS 180

QLDEHMGYLQ SAPLQLMSMQ NLEFIEVTLL TVLTRIIAIV FFRRQELLLW QIGCVLLEYG 240

SPKIKSLAIS FLTELFQLGG LPAQPASTFF SSFLELLKHL VEMDTDQLKL YEEPLSKLIK 300

TLFPFEAEAY RNIEPVYLNM LLEKLCVMFE DGVLMRLKSD LLKAALCHLL QYFLKFVPAG 360

YESALQVRKV YVRNICKALL DVLGIQVDAE YLLGPLYAAL KMESMEIIEE IQCQTQQENL 420

SSNSDGISPK RRRLSSSLNP SKRAPKQTEE IKHVDMNQKS ILWSALKQKA ESLQISLEYS 480

GLKNPVIEML EGIAVVLQLT ALCTVHCSHQ NMNCHTFKDC QHKSKKKPSV VITWMSLEFY 540

TKVLKSCRSL LESVQKPDLE ATIDKVVKIY DALIYMQVNS SFEDHILEDL CGMLSLPWIY 600

SHSDDGCLKL TTFATDLLTL SCRISDSYSP QAQSRCVFLL TLFPRRIFLE WRTAVYNWAL 660

QSSHEVIRAS CVSGFFILLQ QQNSCNRVPK ILIDKVKDDS DIVKKEFASI LGQLVCTLHG 720

MFYLTSSLAE PFSEHGHVDL FCRNLKATSQ HECSSSQLKA SVCKPFLFLL KKKTPSPVKL 780

AFIDNLHHLC KHLDFREDET DVKAVLGTLL NLMEDPDKDV RVAFSGNIKH ILESLDSEDG 840

FIKEVGNFSL KISLTNIYVC VCVCVCLYIH MYVVFNFRAA KGDLVPFALL HLLHCLLSKS 900

ASVSGAAYTE IRALVAAKSV KLQNFFSQYK KPICQFLVES LHSSQMAALP STPCQNADMR 960

KQDVAHQREM ALNTLSEIAN VFDFPDLNRF LTRTLQVLLP DLAAKASPAA SALIRTLGKQ 1020

LNVNRREILI NNFKYIFSHL VCSCSKDELE RALHYLKNET EIELGSLLRQ DFQGLHNELL 1080

LRIGEHYQQV FNGLSILASF ASNDDPYQGP RDTISPELMA DYLQPKLLGI LAFFNMQLLS 1140

SSVGIEDKKM ALNSLMSLMK LMGPKHVSSV RVKMMTTLRT GLRFKDDFPE LCCRAWDCFV 1200

RCLDHACLGS LLSHVIVALL PLIHIQPKET AAIFHYLIIE NRDAVQDFLH EIYFLPDHPE 1260

LKKIKAILQE YRKETSESTD LQTTLQLSMK AIQHENVDVR IHALTSLKET LYKNQEKLIK 1320

YATDSETVEP IISQLVTVLL KGCQDANSQA RLLCGECLGE LGAIDPGRLD FSTTETQGKD 1380

FTFVTGVEDS SFAYGLLMEL TRAYLAYADN SRAQDSAAYA IQELLSIYGC REMETNGPGH 1440

QLWRRFPEHV REILEPHLNT RYKSSQKSTD WSGVKKPIYL SKLGSNFAEW SASWAGYLIT 1500

KVRHDLASKI FTCCNIMMKH DFKVTIYLLP HILVYVLLGC NQEDQQEVYA EIMAVLKHDD 1560

QHTINTQDIA SDLCQLSTQT VFSMLDHLTQ WARHKFQALK AEKCPHSKSN RNKVDSMVST 1620

VDYEDHQSVT RFLDLIPQDT LAVASFRSKA YTRAVMHFES FITEKKQNIQ EHLGFLQKLY 1680

AAMHEPDGVA GVSAIRKAEP SLKEQILEHE SLGLLRDATA CYDRAIQLEP DQIIHYHGVV 1740

KSMLGLGQLS TVITQVNGVH ANRSEWTDEL NTYRVEAAWK LSQWDLVENY LAADGKSTTW 1800

SVRLGQLLLS AKKRDITAFY DTLKVVRAEQ IVPLSAASFE RGSYQRGYEY IVRLHMLCEL 1860

EHSIKPLFQH SPGDSSQEDS LNWVARLEMT QNSYRAKEPI LALRRALLSL NKRPDYNEMV 1920

GECWLQSARV ARKAGHHQTA YNALLNAGES RLAELYVERA KWLWSKGDVH QALIVLQKGV 1980

ELCFPENETP PEGKNMLIHG RAMLLVGRFM EETANFESNA IMKKYKARDV TACLPEWEDG 2040

HFYLAKYYDK LMPMVTDNKM EKQGDLIRYI VLHFGRSLQY GNQFIYQSMP RMLTLWLDYG 2100

TKAYEWEKAG RSDRVQMRND LGKINKVITE HTNYLAPYQF LTAFSQLISR ICHSHDEVFV 2160

VLMEIIAKVF LAYPQQAMWM MTAVSKSSYP VRVNRCKEIL NKAIHMKKSL EKFVGDATRL 2220

TDKLLELCNK PVDGSSSTLS MSTHFKMLKK LVEEATFSEI LIPLQSVMIP TLPSILGTHA 2280

NHASHEPFPG HWAYIAGFDD MVEILASLQK PKKISLKGSD GKFYIMMCKP KDDLRKDCRL 2340

MEFNSLINKC LRKDAESRRR ELHIRTYAVI PLNDECGIIE WVNNTAGLRP ILTKLYKEKG 2400

VYMTGKELRQ CMLPKSASLS EKLKVFLEFL LPRHPPIFHE WFLRTFPDPT SCRSAYCRST 2460

ALMSMVGYIL GLGDRHGENI LFDSLTGECV HVDFNCLFNK GETFEVPEIV PFRLTHNMVN 2520

GMGPMGTEGL FRRACEVTMR LMRDQREPLM SVLKTFLHDP LVEWSKPVKG HSKAPLNETG 2580

EVVNEKAKTH VLDIEQRLQG VIKTRNRVTG LPLSIEGHVH YLIQEATDEN LLCQMYLGWT 2640

PYM 2643

Nucleotide Sequence
(FASTA)

ATGGGGGAAC ATGGCCTGGA GCTGGCTTCC ATGATCCCCG CCCTGCGGGA GCTGGGCAGT 60

GCCACACCAG AGGAATATAA TACAGTTGTA CAGAAGCCAA GACAAATTCT GTGTCAATTC 120

ATTGACCGAA TACTTACAGA TGTAAATGTT GTTGCTGTAG AACTTGTAAA GAAAACTGAC 180

TCTCAGCCAA CCTCCGTGAT GTTGCTTGAT TTCATCCAGC ATATCATGAA ATCCTCCCCA 240

CTTATGTTTG TAAATGTGAA TGGAAGCCAT GAGGCCAAAG GAAGTTGTAT TGAATTCAGT 300

AATTGGATCA TAACAAGACT TCTGCGGATT GCAGCAACTC CCTCCTGTCA TTTGTTACAC 360

AAGAAAATCT GTGAAGTCAT CTGTTCATTA TTATTTCTTT TTAAAAGCAA GAGTCCTGCT 420

ATTTTTGGGG TACTCACAAA AGAATTATTA CAACTTTTTG AAGACTTGGT TTACCTCCAT 480

AGAAGAAATG TGATGGGTCA TGCTGTGGAA TGGCCAGTGC TCATGAGCCG ATTTTTAAGT 540

CAATTAGATG AACACATGGG ATATTTACAA TCAGCTCCTT TGCAGTTGAT GAGTATGCAA 600

AATTTAGAAT TTATTGAAGT CACTTTATTA ACGGTTCTTA CTCGTATTAT TGCAATTGTG 660

TTTTTTAGAA GGCAAGAACT CTTACTTTGG CAGATAGGTT GTGTTCTGCT AGAGTATGGT 720

AGTCCAAAAA TTAAATCCCT AGCAATTAGC TTTTTAACAG AACTTTTTCA GCTTGGAGGA 780

CTACCAGCAC AACCAGCTAG CACTTTTTTC AGCTCATTTT TGGAATTATT AAAACACCTT 840

GTAGAAATGG ATACTGACCA ATTGAAACTC TATGAAGAGC CATTATCAAA GCTGATAAAG 900

ACACTATTTC CCTTTGAAGC AGAAGCTTAT AGAAATATTG AACCTGTCTA TTTAAATATG 960

CTGCTGGAAA AACTCTGTGT CATGTTTGAA GACGGTGTGC TCATGCGGCT TAAGTCTGAT 1020

TTGCTAAAAG CAGCTTTGTG CCATTTACTG CAGTATTTCC TTAAATTTGT GCCAGCTGGG 1080

TATGAATCTG CTTTACAAGT CAGGAAGGTC TATGTGAGAA ATATTTGTAA AGCTCTTTTG 1140

GATGTGCTTG GAATTCAGGT AGATGCAGAG TACTTGTTGG GCCCACTTTA TGCAGCTTTG 1200

AAAATGGAAA GTATGGAAAT CATTGAGGAG ATTCAATGCC AAACTCAACA GGAAAACCTC 1260

AGCAGTAATA GTGATGGAAT ATCACCCAAA AGGCGTCGTC TCAGCTCATC TCTAAACCCT 1320

TCTAAAAGAG CACCAAAACA GACTGAGGAA ATTAAACATG TGGACATGAA CCAAAAGAGC 1380

ATATTATGGA GTGCACTGAA ACAGAAAGCT GAATCCCTTC AGATTTCCCT TGAATACAGT 1440

GGCCTAAAGA ATCCTGTTAT TGAGATGTTA GAAGGAATCG CTGTTGTCTT ACAACTGACT 1500

GCTCTGTGTA CTGTTCATTG TTCTCATCAA AACATGAACT GCCATACTTT CAAGGACTGT 1560

CAACATAAAT CCAAGAAGAA ACCTTCTGTA GTAATAACTT GGATGTCATT GGAGTTTTAC 1620

ACAAAAGTGC TTAAGAGCTG TAGAAGTTTG TTAGAATCTG TTCAGAAACC GGACCTGGAG 1680

GCAACCATTG ATAAGGTGGT GAAAATTTAT GATGCTTTGA TTTATATGCA AGTAAACAGT 1740

TCATTTGAAG ATCATATCCT GGAAGATTTA TGTGGAATGC TCTCACTTCC ATGGATTTAT 1800

TCCCATTCTG ATGATGGCTG TTTAAAGTTG ACCACATTTG CCACTGATCT TCTAACATTA 1860

AGCTGTAGGA TTTCAGATAG CTATTCACCA CAGGCACAAT CACGATGTGT GTTTCTTCTG 1920

ACTCTGTTTC CAAGAAGAAT ATTCCTTGAA TGGAGAACAG CAGTTTACAA CTGGGCCCTG 1980

CAGAGCTCCC ATGAAGTAAT CCGGGCTAGT TGTGTTAGTG GATTTTTTAT CTTATTGCAG 2040

CAGCAGAATT CTTGTAACAG AGTTCCCAAG ATTCTTATAG ATAAAGTCAA AGATGATTCT 2100

GACATTGTCA AGAAAGAATT TGCTTCTATA CTTGGTCAAC TTGTCTGTAC TCTTCACGGC 2160

ATGTTTTATC TGACAAGTTC TTTAGCAGAA CCTTTCTCTG AACATGGACA TGTGGACCTC 2220

TTCTGTAGGA ACTTAAAAGC CACTTCTCAA CATGAATGTT CATCTTCTCA ACTAAAAGCT 2280

TCTGTTTGCA AGCCGTTCCT TTTCCTACTG AAAAAAAAAA CACCTAGTCC AGTAAAACTT 2340

GCTTTCATAG ATAATCTACA TCATCTTTGT AAGCATCTTG ATTTTAGAGA AGATGAAACA 2400

GATGTAAAAG CAGTTCTTGG AACTTTATTA AATTTAATGG AAGATCCAGA CAAAGATGTT 2460

AGAGTGGCTT TTAGTGGAAA TATCAAGCAT ATATTGGAAT CCTTGGACTC TGAAGATGGA 2520

TTTATAAAGG AGGTTGGTAA TTTTTCTCTA AAAATTTCTT TAACCAATAT ATATGTGTGT 2580

GTGTGTGTCT GTGTGTGTTT GTATATTCAT ATGTATGTTG TTTTTAATTT TAGGGCCGCA 2640

AAAGGAGATT TGGTACCTTT TGCACTCTTA CACTTGTTGC ATTGTTTGTT ATCCAAGTCA 2700

GCATCTGTCT CTGGAGCAGC ATACACAGAA ATTAGAGCTC TGGTTGCAGC TAAAAGTGTT 2760

AAACTGCAAA ATTTTTTCAG CCAGTATAAG AAACCCATCT GTCAGTTTTT GGTAGAATCC 2820

CTTCACTCTA GTCAGATGGC AGCACTTCCG AGTACTCCAT GCCAGAATGC TGACATGCGA 2880

AAACAAGATG TGGCTCACCA GAGAGAAATG GCTTTAAATA CCTTGTCTGA AATTGCCAAC 2940

GTTTTCGACT TTCCTGATCT TAATCGTTTT CTTACTAGGA CATTACAAGT TCTACTACCT 3000

GATCTTGCTG CCAAAGCAAG CCCTGCAGCT TCTGCTCTCA TTCGAACTTT AGGAAAACAA 3060

TTAAATGTCA ATCGTAGAGA GATTTTAATA AACAACTTCA AATATATTTT TTCTCATTTG 3120

GTCTGTTCTT GTTCCAAAGA TGAATTAGAA CGTGCCCTTC ATTATCTGAA GAATGAAACA 3180

GAAATTGAAC TGGGGAGCCT GCTGAGACAA GATTTCCAAG GATTGCATAA TGAATTATTG 3240

CTGCGTATTG GAGAACACTA TCAACAGGTT TTCAATGGTT TGTCAATACT TGCCTCATTT 3300

GCATCCAATG ATGATCCGTA TCAGGGCCCA AGAGATACCA TATCACCTGA ACTGATGGCT 3360

GATTATTTAC AACCCAAATT GTTGGGCATT TTGGCTTTTT TTAACATGCA GTTACTGAGC 3420

TCTAGTGTTG GCATCGAAGA TAAGAAAATG GCCTTGAACA GTTTGATGTC TTTGATGAAG 3480

TTAATGGGAC CCAAACATGT CAGTTCTGTG AGGGTGAAGA TGATGACCAC ACTGAGAACT 3540

GGCCTTCGAT TCAAGGATGA CTTTCCTGAA TTGTGTTGCA GAGCTTGGGA CTGCTTTGTT 3600

CGTTGCCTGG ATCATGCTTG TCTGGGCTCC CTTCTCAGTC ATGTAATAGT AGCTTTGTTA 3660

CCTCTTATAC ATATCCAGCC TAAAGAAACT GCAGCTATCT TTCACTACCT CATAATTGAA 3720

AACAGGGATG CTGTGCAAGA TTTTCTTCAT GAAATATATT TTTTACCTGA TCATCCAGAA 3780

TTAAAAAAGA TAAAAGCCAT TCTCCAGGAA TACAGAAAGG AGACCTCTGA GAGCACTGAT 3840

CTTCAAACAA CTCTTCAGCT CTCTATGAAG GCCATTCAAC ATGAAAATGT CGATGTTCGT 3900

ATTCATGCTC TTACAAGCTT GAAGGAAACC TTGTATAAAA ATCAGGAAAA ACTGATAAAG 3960

TATGCAACAG ACAGTGAAAC AGTAGAACCT ATTATCTCAC AGTTGGTGAC AGTGCTTTTG 4020

AAAGGTTGCC AAGATGCAAA CTCTCAAGCT CGGTTGCTCT GTGGGGAATG TTTAGGGGAA 4080

TTGGGGGCGA TAGATCCAGG TCGATTAGAT TTCTCAACAA CTGAAACTCA AGGAAAAGAT 4140

TTTACATTTG TGACTGGAGT AGAAGATTCA AGCTTTGCCT ATGGATTATT GATGGAGCTA 4200

ACAAGAGCTT ACCTTGCATA TGCTGATAAT AGCCGAGCTC AAGATTCAGC TGCCTATGCC 4260

ATTCAGGAGT TGCTTTCTAT TTATGGCTGT AGAGAGATGG AGACCAACGG CCCAGGTCAC 4320

CAGTTGTGGA GGAGATTTCC TGAGCATGTT CGGGAAATAC TAGAACCTCA TCTAAATACC 4380

AGATACAAGA GTTCTCAGAA GTCAACCGAT TGGTCTGGAG TAAAGAAGCC AATTTACTTA 4440

AGTAAATTGG GTAGTAACTT TGCAGAATGG TCAGCATCTT GGGCAGGTTA TCTTATTACA 4500

AAGGTTCGGC ATGATCTTGC CAGTAAAATT TTCACCTGCT GTAACATTAT GATGAAGCAT 4560

GATTTCAAAG TGACCATCTA TCTTCTTCCA CATATTCTGG TGTATGTCCT ACTGGGTTGT 4620

AATCAAGAAG ATCAGCAGGA GGTTTATGCA GAAATTATGG CAGTTCTAAA GCATGACGAT 4680

CAGCATACCA TAAATACCCA AGACATTGCA TCTGATCTGT GTCAACTCAG TACACAGACT 4740

GTGTTCTCCA TGCTTGACCA TCTCACACAG TGGGCAAGGC ACAAATTTCA GGCACTGAAA 4800

GCTGAGAAAT GTCCACACAG CAAATCAAAC AGAAATAAGG TAGACTCAAT GGTATCTACT 4860

GTGGATTATG AAGACCATCA GAGTGTAACC CGTTTTCTAG ACCTCATACC CCAGGATACT 4920

CTGGCAGTAG CTTCCTTTCG CTCCAAAGCA TACACACGAG CTGTAATGCA CTTTGAATCA 4980

TTTATTACAG AAAAGAAGCA AAATATTCAG GAACATCTTG GATTTTTACA GAAATTGTAT 5040

GCTGCTATGC ATGAACCTGA TGGAGTGGCC GGAGTCAGCG CAATTAGAAA GGCAGAACCA 5100

TCTCTAAAAG AACAGATCCT TGAGCATGAA AGCCTTGGCT TGCTGAGGGA TGCCACTGCT 5160

TGTTATGACA GGGCTATTCA GCTAGAACCA GACCAGATCA TTCATTATCA TGGTGTAGTA 5220

AAGTCCATGT TAGGTCTTGG TCAGCTGTCT ACTGTTATCA CTCAGGTGAA TGGAGTGCAT 5280

GCTAACAGGT CCGAGTGGAC AGATGAATTA AACACGTACA GAGTGGAAGC AGCTTGGAAA 5340

TTGTCACAGT GGGATTTGGT GGAAAACTAT TTGGCAGCAG ATGGAAAATC TACAACATGG 5400

AGTGTCAGAC TGGGACAGCT ATTATTATCA GCCAAAAAAA GAGATATCAC AGCTTTTTAT 5460

GACACACTGA AAGTAGTGAG AGCAGAACAA ATTGTACCTC TTTCAGCTGC AAGCTTTGAA 5520

AGAGGCTCCT ACCAACGAGG ATATGAATAT ATTGTGAGAT TGCACATGTT GTGTGAGTTG 5580

GAGCATAGCA TCAAACCACT TTTCCAGCAT TCTCCAGGTG ACAGTTCTCA AGAAGATTCT 5640

CTAAACTGGG TAGCTCGACT AGAAATGACC CAGAATTCCT ACAGAGCCAA GGAGCCTATC 5700

CTGGCTCTCC GGAGGGCCTT ACTAAGCCTC AACAAAAGAC CAGATTACAA TGAAATGGTT 5760

GGAGAATGCT GGCTGCAGAG TGCCAGAGTA GCTAGAAAGG CTGGTCACCA CCAGACAGCC 5820

TACAATGCTC TCCTTAATGC CGGGGAATCA CGACTCGCTG AACTGTATGT GGAAAGGGCA 5880

AAGTGGCTCT GGTCCAAGGG TGATGTTCAC CAGGCACTAA TTGTTCTTCA GAAAGGTGTT 5940

GAATTATGTT TTCCTGAAAA TGAAACCCCA CCTGAGGGTA AGAACATGTT AATCCATGGT 6000

CGAGCTATGC TACTAGTGGG CCGATTTATG GAAGAAACAG CTAACTTTGA AAGCAATGCA 6060

ATTATGAAAA AATATAAGGC AAGAGATGTG ACCGCGTGCC TGCCAGAATG GGAGGATGGG 6120

CATTTTTACC TTGCCAAGTA CTATGACAAA TTGATGCCCA TGGTCACAGA CAACAAAATG 6180

GAAAAGCAAG GTGATCTCAT CCGGTATATA GTTCTTCATT TTGGCAGATC TCTACAATAT 6240

GGAAATCAGT TCATATATCA GTCAATGCCA CGAATGTTAA CTCTATGGCT TGATTATGGT 6300

ACAAAGGCAT ATGAATGGGA AAAAGCTGGC CGCTCCGATC GTGTACAAAT GAGGAATGAT 6360

TTGGGTAAAA TAAACAAGGT TATCACAGAG CATACAAACT ATTTAGCTCC ATATCAATTT 6420

TTGACTGCTT TTTCACAATT GATCTCTCGA ATTTGTCATT CTCATGATGA AGTTTTTGTT 6480

GTCTTGATGG AAATAATAGC CAAAGTATTT CTAGCCTATC CTCAACAAGC AATGTGGATG 6540

ATGACAGCTG TGTCAAAGTC GTCTTATCCC GTGCGTGTGA ACAGATGCAA GGAAATCCTC 6600

AATAAAGCCA TTCATATGAA AAAATCCTTA GAGAAGTTTG TTGGAGATGC AACTCGCCTA 6660

ACAGATAAGC TTCTAGAATT GTGCAATAAA CCGGTTGATG GAAGTAGTTC CACATTAAGC 6720

ATGAGCACTC ATTTTAAAAT GCTTAAAAAG CTGGTAGAAG AAGCAACATT TAGTGAAATC 6780

CTCATTCCTC TGCAATCAGT CATGATACCT ACACTTCCAT CAATTCTGGG TACCCATGCT 6840

AACCATGCTA GCCATGAGCC ATTTCCTGGA CATTGGGCCT ATATTGCAGG GTTTGATGAT 6900

ATGGTGGAAA TTCTTGCCTC TCTTCAGAAA CCAAAGAAGA TTTCTTTAAA AGGGTCAGAT 6960

GGAAAGTTCT ACATCATGAT GTGTAAGCCA AAAGATGACC TGAGAAAGGA TTGTAGACTA 7020

ATGGAATTCA ATTCCTTGAT TAATAAGTGC TTAAGAAAAG ATGCAGAGTC TCGTAGAAGA 7080

GAACTTCATA TTCGAACATA TGCAGTTATT CCACTAAATG ATGAATGTGG GATTATTGAA 7140

TGGGTGAACA ACACTGCTGG TTTGAGACCT ATTCTGACCA AACTATATAA AGAAAAGGGA 7200

GTGTATATGA CAGGAAAAGA ACTTCGCCAG TGTATGCTAC CAAAGTCAGC ATCTTTATCT 7260

GAAAAACTCA AAGTATTCCT AGAATTTCTC CTGCCCAGGC ATCCCCCTAT TTTTCATGAG 7320

TGGTTTCTGA GAACATTCCC TGATCCTACA TCATGTAGAT CAGCATACTG CCGTTCCACT 7380

GCATTAATGT CAATGGTTGG TTATATTCTG GGGCTTGGAG ACCGTCATGG TGAAAATATT 7440

CTCTTTGATT CTTTGACTGG TGAATGTGTA CATGTAGATT TCAACTGTCT TTTCAATAAG 7500

GGAGAAACCT TTGAAGTTCC AGAAATTGTA CCATTTCGCC TGACTCATAA TATGGTTAAT 7560

GGAATGGGTC CTATGGGAAC AGAGGGTCTT TTTCGAAGAG CATGTGAAGT TACAATGAGG 7620

CTGATGCGTG ATCAGCGAGA GCCTTTAATG AGTGTCTTAA AGACTTTTCT ACATGATCCT 7680

CTTGTGGAGT GGAGTAAACC AGTGAAAGGG CATTCCAAAG CACCACTGAA TGAAACTGGA 7740

GAAGTTGTCA ATGAAAAGGC CAAGACCCAT GTTCTTGACA TTGAGCAGCG ACTACAAGGT 7800

GTAATCAAGA CTCGAAATAG AGTAACAGGA CTGCCATTAT CTATTGAAGG ACATGTGCAT 7860

TACCTTATAC AAGAAGCTAC TGATGAAAAC TTACTATGCC AGATGTATCT TGGTTGGACC 7920

CCATATATGT GA 7932

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         iagfd++veilas+qkpkk++l+Gsdgk+y++++k+k+Dlr+d+r+++++sl+N++L+kd

Q: 2295  IAGFDDMVEILASLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKCLRKD  2354

         89**********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +e++rr+L+irty+V+pl++++g+iewv+nt++L+ +l+kl+++k+v++        + +

Q: 2355  AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKLYKEKGVYM--------TGK  2406

         *************************************************........599

S: 121   stvqarkpklkhlklslevfkevlenlvpkdllkklllekfpspeewfelrkaytrslAv  180

         + +q++ pk++ l+++l+vf e+l +++p+ ++++++l++fp+p++    r+ay+rs+A+

Q: 2407  ELRQCMLPKSASLSEKLKVFLEFLLPRHPP-IFHEWFLRTFPDPTS---CRSAYCRSTAL  2462

         *****************************8.**************5...8**********

S: 181   islvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrnivna  240

         +s+vgyiLgLgdrh en+l+d+ tge+vh+df++ f+k++t ++vpe+vPFRLT+n+vn+

Q: 2463  MSMVGYILGLGDRHGENILFDSLTGECVHVDFNCLFNKGET-FEVPEIVPFRLTHNMVNG  2521

         *****************************************.******************

S: 241   lgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk.....kkktsketee  295

         +g++g+eG+fr++ce ++r++r+++e l+++L++fl+dplv+w+k     +k++ +et+e

Q: 2522  MGPMGTEGLFRRACEVTMRLMRDQREPLMSVLKTFLHDPLVEWSKpvkghSKAPLNETGE  2581

         *************************************************99*********

S: 296   elaekakaealkikkllskvekaenavatrdllllee  332

         +++ekak++ l+i+++l++v k++n+v+ ++l+++++

Q: 2582  VVNEKAKTHVLDIEQRLQGVIKTRNRVTGLPLSIEGH  2618

         ********************************99987

Domain Sequence
(FASTA)

IAGFDDMVEI LASLQKPKKI SLKGSDGKFY IMMCKPKDDL RKDCRLMEFN SLINKCLRKD 60

AESRRRELHI RTYAVIPLND ECGIIEWVNN TAGLRPILTK LYKEKGVYMT GKELRQCMLP 120

KSASLSEKLK VFLEFLLPRH PPIFHEWFLR TFPDPTSCRS AYCRSTALMS MVGYILGLGD 180

RHGENILFDS LTGECVHVDF NCLFNKGETF EVPEIVPFRL THNMVNGMGP MGTEGLFRRA 240

CEVTMRLMRD QREPLMSVLK TFLHDPLVEW SKPVKGHSKA PLNETGEVVN EKAKTHVLDI 300

EQRLQGVIKT RNRVTGLPLS IEGH 324

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0071480	; P:cellular response to gamma radiation
GO:0034644	; P:cellular response to UV
GO:0000077	; P:DNA damage checkpoint
GO:0008156	; P:negative regulation of DNA replication
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043517	; P:positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046777	; P:protein autophosphorylation
GO:0090399	; P:replicative senescence

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR003152	; FATC.
IPR021133	; HEAT_type_2.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR011990	; TPR-like_helical.
IPR012993	; UME.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08064	; UME; 1.

SMARTs

SM00146	; PI3Kc; 1.
SM00802	; UME; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS50077	; HEAT_REPEAT; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013