EKS-NOL-00303

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00303

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	311.8	3.6E-93	15	281	267

Status

Unreviewed

Ensembl Protein

ENSNLEP00000006265

UniProt Accession

G1QZ94;

Protein Name

Protein Synonyms/Alias

Gene Name

MYO3B

Gene Synonyms/Alias

MYO3B;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000005050	ENSNLEP00000006262	ENSNLET00000006579
ENSNLEG00000005050	ENSNLEP00000006265	ENSNLET00000006582

Organism

Nomascus leucogenys

Functional Description

Protein Length

1329

Protein Sequence
(FASTA)

MMLGLESLPD PTDTWEIIET IGKGTYGKVY KVTNKRDGSL AAVKILDPIS DMDEEIEAEY 60

NILQFLPNHP NVVKFYGMFY KADHCAGGQL WLVLELCNGG SVTELVKGLL RCGQRLDEAM 120

ISYILYGALL GLQHLHNNRI IHRDVKGNNI LLTTEGGVKL VDFGVSAQLT STRLRRNTSV 180

GTPFWMAPEV IACEQQYDSS YDARCDVWSL GITAIELGDG DPPLFDMHPV KTLFKIPRNP 240

PPTLLHPEKW CEEFNHFISQ CLIKDFERRP SVTHLLDHPF IKGVHGKVLF LQKQLAKVLQ 300

DQKHQNPVAK TRHERMHTRR PYHVEDAEKY CLEDDLVNLE VLDEDTIIHQ LQKRYADLLI 360

YTYVGDILIA LNPFQSLSIY SPQFSRLYHG VKRASNPPHI FASADAAYQC MVTLSKDQCI 420

VISGESGSGK TESAHLIVQH LTFLGKANNQ TLREKILQVN SLVEAFGNSC TAINDNSSRF 480

GKYLEMMFTP TGVVMGARIS EYLLEKSRVI KQAAGEKNFH IFYYIYAGLH HQKKLSDFRL 540

PEEKPPRYIA DETGRVMHDI TSKESYRRRF EAIQHCFRII GFTDKEVHSV YRILAGILNI 600

GNIEFAAISS QHQSDKSEVP NAEALQNAAS VLCISPEELQ EALTSHCVVT RGETIIRANT 660

VDRAADVRDA MSKALYGRLF SWIVNRINTL LQPDKNICSA GDGMNVGILD IFGFENFQRN 720

SFEQLCINIA NEQIQYYFNQ HVFALEQMEY QNEGIDAIPV EYEDNRPLLD MFLQKPLGLL 780

ALLDEESRFP QATDQTLVDK FEDNLRCKYF WRPKGVELCF GIQHYAGKVL YDASGVLEKN 840

RDTLPADVVV VLRTSENKLL QQLFSIPLTK TGNLAQTRAR ITVASRSLPP HFSAGKAKVD 900

TLEVMRHPEE TTNMKRQTVA SYFRYSLMDL LSKMVVGQPH FVRCIKPNDD REALQFSRER 960

VLAQLRSTGI LETVSIRRQG YSHRILFEEF VKRYYYLAFR AHQTPLASKE SCVAILEKSR 1020

LDHWVLGKTK VFLKYYHVEQ LNLLLREVIG RVVVLQAYTK GWLGARRYKR VREKREKGAI 1080

AIQSAWRGYD ARRKFKKISN RRNESAAHNQ AGDTSNQSSG PHSPIAAATR GSAKVQDCSE 1140

PGDHKVLRGS VDRRSHSEAE SNNGHAQTSS NSLAVTEKNG HSQAQSSPKG CDIFAGHANK 1200

HSVSGTDLLS SRICHPAPDH QGLSLWGAPQ KPGSENGLAQ KHRTPRRRCQ QPKMLSSPED 1260

TMYYNQLNGT LEYQGSKRKP RKLGQIKVLD GEDEYYKSLS PVDCIPEENN SAHPSFCSSS 1320

SKGDSFAQH 1329

Nucleotide Sequence
(FASTA)

ATGATGCTTG GACTTGAATC GCTTCCAGAT CCCACGGACA CCTGGGAAAT TATAGAGACC 60

ATTGGTAAAG GCACCTATGG CAAGGTCTAT AAGGTAACTA ACAAGAGAGA TGGGAGCCTG 120

GCTGCAGTGA AAATTCTGGA TCCAATCAGT GATATGGATG AAGAAATTGA GGCAGAATAC 180

AACATTTTGC AGTTCCTTCC TAATCATCCC AATGTGGTAA AGTTTTATGG GATGTTTTAC 240

AAAGCGGATC ACTGCGCAGG GGGACAGCTG TGGCTGGTCC TGGAGCTGTG TAATGGGGGC 300

TCAGTCACTG AGCTTGTCAA AGGTCTACTC AGATGTGGCC AGCGGTTGGA TGAAGCAATG 360

ATCTCATACA TCTTGTACGG GGCCCTCTTG GGCCTTCAGC ATTTGCACAA CAACCGAATC 420

ATCCACCGTG ATGTGAAGGG GAATAACATT CTTCTGACAA CAGAAGGAGG AGTTAAGCTC 480

GTTGACTTTG GTGTTTCAGC CCAACTCACC AGTACACGTC TGCGGAGAAA CACATCTGTT 540

GGCACCCCAT TCTGGATGGC CCCTGAGGTC ATTGCCTGTG AGCAGCAGTA TGACTCTTCC 600

TATGACGCTC GCTGTGACGT CTGGTCCTTG GGGATCACAG CTATTGAACT GGGGGATGGA 660

GACCCTCCCC TCTTTGACAT GCATCCTGTG AAAACACTCT TTAAGATTCC AAGAAATCCT 720

CCACCTACTT TACTTCATCC AGAAAAATGG TGTGAAGAAT TCAACCACTT TATTTCACAG 780

TGTCTTATTA AGGATTTTGA AAGGCGACCT TCCGTCACAC ATCTCCTTGA CCACCCATTT 840

ATTAAAGGAG TACATGGAAA GGTTCTGTTT CTGCAGAAAC AGCTGGCCAA GGTTCTCCAA 900

GACCAGAAGC ATCAAAATCC TGTTGCTAAA ACCAGGCATG AGAGGATGCA TACCAGAAGA 960

CCTTATCATG TGGAAGATGC TGAAAAATAC TGCCTCGAGG ATGATTTGGT CAACCTAGAG 1020

GTTCTGGATG AGGATACAAT TATCCATCAG TTGCAGAAAC GTTATGCAGA CTTGCTAATT 1080

TACACATATG TTGGAGACAT CTTAATTGCC TTAAACCCCT TCCAGAGTCT AAGCATATAC 1140

TCTCCACAGT TTTCCAGGCT TTATCATGGG GTGAAACGTG CCTCCAATCC CCCCCACATA 1200

TTTGCATCAG CAGATGCTGC TTACCAGTGC ATGGTTACTC TCAGCAAAGA CCAGTGCATT 1260

GTCATCAGTG GAGAGAGTGG CTCTGGGAAG ACAGAAAGCG CCCACCTGAT TGTTCAGCAT 1320

TTGACTTTCT TGGGAAAGGC CAATAATCAG ACCTTGAGAG AGAAAATTCT ACAAGTCAAC 1380

TCCCTGGTGG AAGCCTTTGG GAACTCATGC ACTGCCATCA ATGACAACTC AAGCCGTTTT 1440

GGAAAATATC TGGAAATGAT GTTTACACCA ACTGGAGTTG TGATGGGGGC AAGAATCTCT 1500

GAATATCTCC TTGAAAAATC CAGAGTTATA AAACAGGCAG CGGGAGAGAA AAATTTTCAC 1560

ATATTTTACT ATATTTATGC TGGTCTTCAT CACCAAAAGA AGCTTTCTGA CTTCAGACTT 1620

CCTGAGGAAA AACCTCCTAG GTACATAGCT GATGAAACTG GAAGGGTGAT GCATGACATA 1680

ACTTCCAAGG AGTCTTACAG AAGACGATTC GAAGCAATTC AGCATTGCTT CAGGATTATA 1740

GGGTTCACGG ACAAAGAGGT GCACTCAGTG TACAGAATTT TGGCTGGGAT TTTGAATATT 1800

GGGAACATTG AGTTTGCAGC TATTTCCTCT CAACATCAGA GTGATAAAAG TGAGGTGCCC 1860

AATGCTGAAG CTTTGCAAAA TGCTGCCTCT GTTCTGTGCA TCAGCCCCGA AGAGCTCCAG 1920

GAGGCCCTCA CCTCCCACTG TGTGGTCACC CGGGGCGAGA CCATCATCCG TGCCAACACT 1980

GTAGACAGGG CTGCGGACGT TCGAGACGCC ATGTCCAAAG CCCTGTACGG GAGGCTCTTC 2040

AGCTGGATTG TGAATCGCAT TAATACACTC CTGCAGCCAG ACAAAAACAT ATGTAGTGCA 2100

GGAGATGGAA TGAACGTGGG GATCTTGGAT ATCTTTGGAT TTGAGAATTT TCAGAGAAAT 2160

TCATTTGAGC AGCTCTGCAT AAACATCGCC AATGAGCAAA TCCAGTACTA TTTCAATCAG 2220

CACGTTTTTG CTCTTGAGCA GATGGAATAT CAGAATGAAG GCATTGATGC TATACCCGTG 2280

GAATATGAGG ACAACCGCCC GCTCTTGGAC ATGTTCCTTC AGAAACCCCT GGGACTACTT 2340

GCACTTTTGG ATGAGGAAAG TCGGTTTCCC CAAGCAACTG ACCAGACCCT GGTTGATAAA 2400

TTTGAAGATA ATCTACGATG CAAATACTTC TGGAGGCCCA AAGGAGTGGA ACTGTGCTTT 2460

GGCATTCAGC ATTATGCTGG AAAGGTATTA TATGATGCTT CTGGGGTTCT TGAGAAAAAT 2520

AGAGACACTC TCCCTGCTGA TGTGGTTGTG GTCCTGAGAA CGTCAGAAAA CAAGCTTCTT 2580

CAGCAGCTCT TCTCAATCCC TCTGACCAAA ACAGGTAATT TGGCCCAGAC AAGAGCTAGG 2640

ATAACAGTGG CCTCAAGATC TTTGCCTCCA CATTTCAGTG CTGGAAAAGC CAAGGTGGAC 2700

ACTCTGGAGG TGATGCGGCA TCCGGAAGAA ACCACCAACA TGAAGAGGCA AACTGTGGCT 2760

TCTTACTTCC GGTATTCTCT GATGGACCTG CTCTCCAAAA TGGTGGTTGG ACAGCCCCAC 2820

TTTGTGCGCT GCATTAAACC CAATGATGAC CGAGAGGCCC TGCAGTTCTC TCGAGAGAGG 2880

GTGCTGGCCC AGCTCCGCTC CACAGGGATT CTGGAGACAG TCAGCATCCG CCGCCAGGGC 2940

TATTCCCACC GCATCCTCTT TGAAGAATTT GTGAAAAGGT ATTATTACTT GGCATTCAGA 3000

GCACATCAAA CACCTCTTGC TAGCAAAGAG AGCTGTGTGG CTATCTTGGA AAAGTCCAGA 3060

TTAGATCACT GGGTGCTGGG AAAAACAAAG GTTTTTCTCA AATATTACCA TGTTGAGCAA 3120

TTAAATTTGC TACTTCGAGA AGTCATAGGC AGAGTGGTTG TGCTACAGGC ATATACAAAG 3180

GGGTGGCTTG GAGCCAGGAG ATACAAAAGA GTCAGAGAGA AGAGAGAGAA GGGAGCCATT 3240

GCCATCCAGT CAGCCTGGAG AGGATATGAT GCTCGGAGGA AATTTAAGAA AATAAGCAAC 3300

AGAAGGAATG AGTCTGCTGC TCATAATCAA GCAGGGGACA CTTCAAACCA AAGCAGTGGG 3360

CCACATTCCC CCATCGCAGC AGCTACCAGG GGAAGTGCCA AGGTTCAAGA CTGCAGCGAG 3420

CCTGGTGACC ATAAAGTTCT CAGGGGCTCG GTAGATCGTA GAAGCCATTC AGAAGCAGAG 3480

TCCAACAATG GCCATGCACA GACTTCAAGC AACTCTCTTG CTGTCACAGA GAAAAATGGG 3540

CACTCACAAG CCCAGAGTTC TCCAAAAGGG TGCGATATCT TCGCAGGACA TGCAAACAAG 3600

CACTCGGTTT CTGGGACTGA TTTGCTGTCT TCTCGGATAT GCCATCCTGC TCCAGATCAC 3660

CAAGGATTGA GTCTCTGGGG AGCCCCTCAA AAGCCTGGTT CAGAAAATGG TCTCGCACAG 3720

AAGCATCGAA CACCTCGCCG ACGATGTCAG CAGCCCAAAA TGCTGAGTAG CCCTGAGGAC 3780

ACCATGTACT ATAACCAGTT AAATGGAACT CTAGAATATC AAGGGAGCAA GAGGAAGCCA 3840

AGAAAACTTG GCCAAATCAA AGTACTTGAT GGGGAAGATG AATATTACAA ATCTCTGTCA 3900

CCAGTGGACT GTATCCCTGA GGAGAACAAC TCAGCCCACC CTTCCTTTTG TTCTTCATCC 3960

TCAAAAGGAG ACTCTTTTGC TCAACATTGA 3990

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekqekleelqkeisvlkkl.khpniv  59

         +e++e+igkG++gkvy+ ++k+ g+l+a+k+++  + ++ ee++ e+++l+ l +hpn+v

Q: 15    WEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDPIS-DMDEEIEAEYNILQFLpNHPNVV  73

         799******************************998.99************98356****

S: 60    eylesflk.....eeelwlvmeylagGslsdlvk..eelkselkEeqiayilrevlkaLe  112

         +++++f+k       +lwlv+e+++gGs+++lvk    + ++l+E  i+yil ++l +L+

Q: 74    KFYGMFYKadhcaGGQLWLVLELCNGGSVTELVKglLRCGQRLDEAMISYILYGALLGLQ  133

         ********9888889*******************777899********************

S: 113   ylHskkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtpywmAPEviaq  172

         +lH++++iHrd+k++niLlt+eg VkL+dfgv+aql++tr +r+t vgtp+wmAPEvia+

Q: 134   HLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRLRRNTSVGTPFWMAPEVIAC  193

         ************************************************************

S: 173   e...ekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklkskkkfske  229

         e   +++Yd+++D+wslGItaiel +g+pP++d++p+k l+ki++n+pp+l +++k+++e

Q: 194   EqqyDSSYDARCDVWSLGITAIELGDGDPPLFDMHPVKTLFKIPRNPPPTLLHPEKWCEE  253

         9888899*****************************************************

S: 230   fkefvekclqknpekRpsasellkhkFl  257

         f++f+++cl k++e+Rps+++ll+h+F+

Q: 254   FNHFISQCLIKDFERRPSVTHLLDHPFI  281

         ***************************7

Domain Sequence
(FASTA)

WEIIETIGKG TYGKVYKVTN KRDGSLAAVK ILDPISDMDE EIEAEYNILQ FLPNHPNVVK 60

FYGMFYKADH CAGGQLWLVL ELCNGGSVTE LVKGLLRCGQ RLDEAMISYI LYGALLGLQH 120

LHNNRIIHRD VKGNNILLTT EGGVKLVDFG VSAQLTSTRL RRNTSVGTPF WMAPEVIACE 180

QQYDSSYDAR CDVWSLGITA IELGDGDPPL FDMHPVKTLF KIPRNPPPTL LHPEKWCEEF 240

NHFISQCLIK DFERRPSVTH LLDHPFI 267

Keyword

ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0016459	; C:myosin complex
GO:0005524	; F:ATP binding
GO:0003774	; F:motor activity
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000048	; IQ_motif_EF-hand-BS.
IPR011009	; Kinase-like_dom.
IPR001609	; Myosin_head_motor_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00612	; IQ; 1.
PF00063	; Myosin_head; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00015	; IQ; 2.
SM00242	; MYSc; 1.
SM00220	; S_TKc; 1.

Prosites

PS50096	; IQ; 2.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR00193

; MYOSINHEAVY.

Created Date

20-Feb-2013