EKS-NOL-00143

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00143

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	520.7	9.5E-157	90	383	294

Status

Unreviewed

Ensembl Protein

ENSNLEP00000006606

UniProt Accession

G1R085;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38L

Gene Synonyms/Alias

STK38L;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000005439	ENSNLEP00000024154	ENSNLET00000032522
ENSNLEG00000005439	ENSNLEP00000006606	ENSNLET00000006938

Organism

Nomascus leucogenys

Functional Description

Protein Length

464

Protein Sequence
(FASTA)

MAMTAGTTTT FPMSNHTRER VTVAKLTLEN FYSNLILQHE ERETRQKKLE VAMEEEGLAD 60

EEKKLRRSQH ARKETEFLRL KRTRLGLDDF ESLKVIGRGA FGEVRLVQKK DTGHIYAMKI 120

LRKADMLEKE QVAHIRAERD ILVEADGAWV VKMFYSFQDK RNLYLIMEFL PGGDMMTLLM 180

KKDTLTEEET QFYISETVLA IDAIHQLGFI HRDIKPDNLL LDAKGHVKLS DFGLCTGLKK 240

AHRTEFYRNL THNPPSDFSF QNMNSKRKAE TWKKNRRQLA YSTVGTPDYI APEVFMQTGY 300

NKLCDWWSLG VIMYEMLIGY PPFCSETPQE TYRKVMNWKE TLVFPPEVPI SEKAKDLILR 360

FCIDSENRIG NSGVEEIKGH PFFEGVDWEH IRERPAAIPI EIKSIDDTSN FDDFPESDIL 420

QPVPNTTEPD YKSKDWVFLN YTYKRFEGLT QRGSIPTYMK AGKL 464

Nucleotide Sequence
(FASTA)

ATGGCAATGA CGGCAGGGAC TACAACAACC TTTCCTATGA GCAACCATAC CCGGGAAAGA 60

GTGACTGTAG CCAAGCTCAC ATTGGAGAAT TTTTATAGCA ACCTAATTTT ACAGCATGAA 120

GAGAGAGAAA CCAGGCAGAA GAAATTAGAA GTGGCCATGG AAGAAGAAGG ATTAGCAGAT 180

GAAGAGAAAA AGTTGCGTCG ATCACAACAC GCTCGCAAAG AAACAGAGTT CTTACGGCTC 240

AAAAGGACCA GACTTGGCTT GGATGACTTT GAGTCTCTGA AAGTTATAGG AAGAGGAGCT 300

TTTGGAGAGG TGCGGTTGGT CCAGAAGAAA GATACAGGCC ATATCTATGC AATGAAGATA 360

TTGAGAAAGG CTGATATGCT TGAAAAAGAG CAGGTGGCCC ATATCCGAGC AGAAAGAGAT 420

ATTTTGGTAG AAGCAGATGG TGCCTGGGTG GTGAAGATGT TTTATAGTTT TCAGGATAAG 480

AGGAATCTTT ATCTAATCAT GGAATTTCTC CCTGGAGGTG ACATGATGAC ATTGCTAATG 540

AAGAAAGACA CCTTGACAGA AGAGGAAACA CAGTTCTACA TTTCAGAGAC TGTTCTGGCA 600

ATAGATGCGA TCCACCAGTT GGGTTTCATC CATCGGGATA TTAAGCCAGA CAACCTTTTA 660

TTGGATGCCA AGGGTCATGT AAAATTGTCT GATTTTGGTT TATGTACGGG ATTAAAGAAA 720

GCTCACAGGA CTGAATTTTA TAGAAATCTC ACACACAACC CACCAAGTGA CTTCTCATTT 780

CAGAACATGA ACTCAAAGAG GAAAGCAGAA ACTTGGAAGA AGAACAGGAG ACAACTGGCA 840

TATTCCACAG TTGGGACACC AGATTACATT GCTCCAGAAG TATTCATGCA GACTGGTTAC 900

AACAAATTGT GTGACTGGTG GTCTTTGGGA GTGATTATGT ATGAAATGCT AATAGGATAT 960

CCACCTTTCT GCTCTGAAAC ACCTCAAGAA ACATACAGAA AAGTGATGAA CTGGAAAGAA 1020

ACTCTGGTAT TTCCTCCAGA GGTACCTATA TCTGAGAAAG CCAAGGACTT AATTCTCAGA 1080

TTTTGTATTG ATTCTGAAAA CAGAATTGGA AATAGTGGAG TAGAAGAAAT AAAAGGTCAT 1140

CCCTTTTTTG AAGGTGTCGA CTGGGAGCAC ATAAGGGAAA GGCCAGCAGC AATCCCTATA 1200

GAAATCAAAA GCATTGATGA TACTTCAAAT TTTGATGACT TCCCTGAATC TGATATTTTA 1260

CAACCAGTGC CAAATACCAC AGAACCAGAC TACAAATCCA AAGACTGGGT TTTTCTCAAT 1320

TATACCTATA AAAGGTTTGA AGGGTTGACT CAACGTGGCT CTATCCCCAC CTACATGAAA 1380

GCTGGGAAAT TATGA 1395

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt+++ya+kilrk+d+l+k+qvah++aerdil+ead +w

Q: 90    FESLKVIGRGAFGEVRLVQKKDTGHIYAMKILRKADMLEKEQVAHIRAERDILVEADGAW  149

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk+nlyl+me+lPGGd+mtll+kk++l+ee+++fyi+e+vla++++h+lGf

Q: 150   VVKMFYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGF  209

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+dakGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+++++  ++ +

Q: 210   IHRDIKPDNLLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRKA  269

         *************************************************65555555555

S: 181   rkkkknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPflaetpq  240

            kknrr+lays+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++etpq

Q: 270   ETWKKNRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQ  329

         555*********************************************************

S: 241   etykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         ety+kv+nwketl fp+ev++se+akdli r+++d+e+r+g++Gv+eik hpff

Q: 330   ETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPFF  383

         *****************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHIYAMK ILRKADMLEK EQVAHIRAER DILVEADGAW 60

VVKMFYSFQD KRNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYISETVL AIDAIHQLGF 120

IHRDIKPDNL LLDAKGHVKL SDFGLCTGLK KAHRTEFYRN LTHNPPSDFS FQNMNSKRKA 180

ETWKKNRRQL AYSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYRKVMNWK ETLVFPPEVP ISEKAKDLIL RFCIDSENRI GNSGVEEIKG HPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0005886	; C:plasma membrane
GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007243	; P:intracellular protein kinase cascade

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013