EPS-NOL-00029

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00029

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.9	7.9E-57	783	1029	247

Status

Unreviewed

Ensembl Protein

ENSNLEP00000006988

UniProt Accession

G1R1B6;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP2

Gene Synonyms/Alias

PHLPP2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000005761	ENSNLEP00000006988	ENSNLET00000007335

Organism

Nomascus leucogenys

Functional Description

Protein Length

1321

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVKR GCVYLYGADT TTATTTTTTS SSSSSSSSSS 60

DLHLVLCTVE TPASEICAGE GRESLYLQLH GDLVRRLEPT ERPLQIVYDY LSRLGFDDPV 120

RIQEEATNPD LSCMIRFYGE KPCHMDHLDR ILLSGIYNVR KGKTQLHKWA ERLVVLCGTC 180

LIVSSVKDCQ TGKMHILPLV GGKIEEVKRR QYSLAFSSAG AQAQTYHVSF ETLAEYQRWQ 240

RQASKVVSQR ISTVDLSCYS LEEVPEHLFY SQDITYLNLR HNFMQLERPG GLDTLYKFSQ 300

LKGLNLSHNK LGLFPILLCE ISTLTELNLS CNGFYDLPSQ IGNLLNLQTL CLDGNFLTTL 360

PEELGNLQQL SSLGISFNNF SQIPEVYEKL TMLDRVVMAG NCLEVLNLGV LNRMNHIKHV 420

DLRMNHLKTM LTENLEGNKH ITHVDLRDNQ LTDLDLSSLC SLEQLHCERN QLRELTLSGF 480

SLRTLYASSN KLTAVSVYPV PSLLTSLDLS RNLLECVPDW ACEAKKIEVL DVSYNLLTEV 540

PVRILSSLSL RKLMLGHNHV QNLPTLVEHI PLEVLDLQHN ALTRLPDTLF SKALNLRYLN 600

ASANSLESLP STCTGEESLS MLQLLYLTNN LLTDQCIPVL VGHLHLRILH LANNQLQTFP 660

ASKLNKLEQL EELNLSGNKL KTIPTTIANC KRLHTLVAHS NNISIFPEIL QLPQIQVLLC 720

AGMVSLLGEM AGESVNEIIL IRKNIIVFLR TPRLDTWDHI TTLKIDQKPL PTTDSTVTST 780

FWSHGLAEMA GQRNKLCVSA LAMDNFAEGV GAVYGMFDGD RNEELPRLLQ CTMADVLLEE 840

VQQSTNDTVF MANTFLVSHR KLGMAGQKLG SSALLCYIRP DTVDPASSFS LTVANVGTCQ 900

AVLCRGGKPV PLSKVFSLEQ DPEEAQRVKD QKAIITEDNK VNGVTCCTRM LGCTYLYPWI 960

LPKPHISSTP LTIQDELLIL GNKALWEHLS YTEAVNAVRH VQDPLAAAKK LCTLAQSYGC 1020

QDNVGAMVVY LNIGEEGCTC EMNGLTLPGP VGFASTTTIK DAPKPATPSS SSGIASEFSS 1080

EMSTSEVSSE VGSTASDEHN AGGLDAALLL RPERRCSLHP TPTSGLFQRQ PSCATFSSNQ 1140

SDNGLDSDDD QPVEGVITNG SKVEVEVDIH CCRGRDLENS PPLIESSPTP CSEEHARGSC 1200

FGIRRQNSVN SGILLPMSKD RMELQKSPST SCLYGKKLSN GSIVPLEDSL NLIEVATEVP 1260

KRKTGYFAAP TQMEPEDQFV VPRDLEEEVK EQMKQHQDSR LEPEPLEEDR TEPPEEFDTA 1320

L 1321

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGAAGCAG AAATTGTTTG AATAGGAGAA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TAAGAGAAGA TGTAAAGAGA GGCTGTGTTT ACCTTTATGG AGCAGACACT 120

ACCACTGCCA CTACAACCAC CACCACCTCC TCTTCCTCTT CCTCCTCCTC CTCTTCCTCT 180

GACTTACATC TGGTCCTTTG CACTGTAGAG ACACCAGCAT CAGAAATATG TGCTGGAGAG 240

GGAAGAGAAA GTCTTTATTT ACAGCTTCAT GGAGACCTGG TCAGGAGACT GGAACCTACT 300

GAACGACCTC TTCAGATTGT TTATGATTAC TTATCCAGGC TGGGATTTGA TGATCCTGTG 360

CGCATACAAG AGGAGGCTAC AAATCCTGAC CTCAGCTGTA TGATTCGATT TTATGGTGAA 420

AAACCATGCC ACATGGATCA TTTGGATCGA ATCCTACTGT CTGGCATCTA TAATGTACGC 480

AAGGGAAAGA CCCAGCTGCA TAAGTGGGCT GAGCGCCTAG TTGTCCTCTG TGGTACCTGC 540

CTTATTGTTT CCTCAGTGAA GGATTGTCAG ACTGGAAAGA TGCACATTTT GCCTCTGGTT 600

GGTGGAAAGA TAGAAGAAGT GAAGCGACGG CAATACTCCC TTGCTTTCAG CTCAGCAGGA 660

GCCCAAGCTC AGACCTATCA TGTCAGCTTC GAGACTTTGG CCGAGTACCA GCGATGGCAA 720

CGGCAAGCAT CCAAGGTGGT GTCCCAGCGA ATCAGTACCG TGGATCTCTC ATGTTACAGC 780

CTCGAGGAGG TTCCTGAGCA TCTCTTCTAT AGTCAAGATA TTACCTACCT CAACTTGCGA 840

CACAACTTCA TGCAGTTAGA AAGACCCGGA GGCCTCGATA CACTCTACAA ATTTTCTCAA 900

CTGAAGGGCC TGAACTTGTC CCATAATAAA CTTGGGTTGT TTCCTATATT GTTATGCGAG 960

ATCTCTACCC TGACTGAGCT CAACCTTTCC TGTAATGGAT TTTATGACCT ACCAAGTCAA 1020

ATTGGCAATC TGCTAAATCT TCAAACCCTC TGTCTTGATG GCAACTTTCT GACTACTTTA 1080

CCTGAAGAAT TGGGAAATCT ACAACAGCTT TCCTCCTTGG GAATTTCCTT CAACAACTTT 1140

AGTCAGATTC CTGAGGTTTA TGAGAAACTC ACTATGTTAG ATAGAGTGGT TATGGCAGGA 1200

AATTGCCTGG AAGTCCTGAA CTTAGGGGTG CTGAATAGGA TGAACCATAT CAAGCATGTG 1260

GATTTAAGGA TGAACCATTT GAAAACCATG CTTACTGAAA ATCTGGAGGG AAATAAACAC 1320

ATCACCCATG TGGATCTGCG GGATAACCAA CTGACTGACT TGGATCTTAG CTCCTTATGC 1380

AGCTTGGAAC AGCTGCACTG TGAGCGGAAT CAGCTGAGGG AGCTAACACT CAGTGGCTTC 1440

TCCCTTCGGA CCCTCTATGC CAGTTCCAAC AAGCTGACAG CAGTGAGCGT CTATCCAGTA 1500

CCCAGCCTGC TCACTTCCTT GGATCTCTCC CGAAACCTGC TAGAGTGTGT CCCTGACTGG 1560

GCCTGTGAAG CAAAGAAGAT AGAAGTATTA GATGTGAGCT ATAATCTTCT CACAGAGGTT 1620

CCCGTGAGAA TTCTAAGTAG CTTGAGTCTT AGAAAACTGA TGCTGGGACA CAATCATGTG 1680

CAAAACCTCC CAACACTGGT AGAGCACATC CCCCTTGAGG TGTTGGATCT TCAGCATAAT 1740

GCACTCACGA GGCTGCCAGA CACCCTCTTC TCCAAGGCCT TAAATCTCAG ATACTTGAAT 1800

GCATCTGCAA ATAGTTTGGA GTCTTTACCA TCCACCTGCA CTGGAGAGGA GAGTTTGAGT 1860

ATGCTGCAGC TGCTTTATCT GACCAACAAT CTCCTGACGG ATCAGTGCAT ACCTGTCCTG 1920

GTAGGGCACC TGCACCTGCG AATCTTGCAC CTTGCAAACA ATCAGTTACA GACCTTTCCT 1980

GCAAGCAAAC TAAATAAATT GGAGCAATTG GAGGAACTGA ACCTAAGTGG CAACAAGCTT 2040

AAAACCATTC CCACAACCAT AGCAAACTGC AAAAGGCTGC ACACCCTTGT CGCACACTCC 2100

AACAACATCA GCATTTTCCC AGAAATACTG CAGTTGCCTC AGATCCAGGT ACTTCTGTGT 2160

GCTGGCATGG TGTCCTTATT GGGGGAAATG GCAGGAGAGA GTGTGAATGA GATTATTCTC 2220

ATAAGGAAAA ATATTATTGT CTTCTTACGT ACTCCAAGAT TGGATACTTG GGACCATATC 2280

ACAACCCTGA AAATTGATCA GAAACCTTTG CCAACCACAG ATTCTACAGT TACATCAACC 2340

TTCTGGAGCC ATGGACTGGC TGAGATGGCA GGGCAGAGAA ATAAGCTGTG TGTCTCAGCA 2400

CTTGCTATGG ATAACTTTGC AGAGGGGGTG GGAGCTGTGT ATGGCATGTT TGATGGAGAC 2460

CGAAATGAGG AGCTCCCACG CCTGCTGCAG TGTACAATGG CAGATGTGCT TTTAGAAGAG 2520

GTACAGCAAT CAACTAATGA CACGGTTTTC ATGGCTAACA CCTTCTTGGT ATCTCACAGG 2580

AAATTAGGAA TGGCTGGCCA GAAGTTGGGC TCCTCCGCTC TCCTGTGCTA CATCCGCCCT 2640

GACACTGTTG ATCCAGCAAG TAGCTTTAGC TTGACTGTAG CCAATGTTGG CACATGCCAA 2700

GCAGTCCTGT GCCGAGGTGG GAAGCCAGTG CCCCTCTCTA AAGTCTTCAG CCTGGAGCAG 2760

GACCCAGAGG AGGCGCAAAG GGTGAAGGAC CAAAAAGCCA TCATCACAGA GGACAACAAA 2820

GTGAATGGGG TAACCTGCTG TACCCGCATG CTGGGCTGTA CATACCTCTA CCCTTGGATC 2880

CTCCCCAAGC CCCACATATC TTCCACTCCG CTGACCATTC AAGATGAGTT GCTGATTCTG 2940

GGAAACAAAG CATTGTGGGA ACACTTGTCC TACACAGAAG CTGTCAATGC TGTACGTCAT 3000

GTACAAGACC CATTAGCAGC TGCTAAGAAG CTGTGCACAT TAGCGCAGAG CTATGGCTGT 3060

CAGGACAATG TAGGGGCGAT GGTGGTTTAT TTGAATATTG GTGAGGAAGG CTGCACTTGT 3120

GAAATGAATG GGCTCACCCT CCCAGGTCCT GTGGGATTTG CTTCAACCAC CACTATCAAG 3180

GATGCCCCTA AGCCAGCCAC TCCATCCTCT AGCAGTGGGA TTGCCTCTGA GTTCAGCAGT 3240

GAGATGTCCA CCTCAGAGGT GAGCAGTGAA GTGGGGTCCA CTGCTTCTGA TGAGCATAAT 3300

GCTGGGGGCC TGGACGCTGC CTTGCTTCTG AGGCCAGAGC GGCGCTGCAG CCTCCACCCA 3360

ACACCCACCT CTGGGCTGTT TCAGCGCCAG CCTTCTTGTG CTACCTTCTC CAGTAACCAG 3420

TCTGACAATG GCCTGGACAG TGATGATGAC CAGCCCGTTG AGGGGGTCAT AACCAATGGC 3480

AGCAAGGTAG AGGTGGAAGT AGACATCCAC TGCTGCAGGG GGAGGGATCT GGAGAACTCA 3540

CCCCCTCTCA TAGAGAGTTC TCCTACCCCG TGTTCTGAGG AACATGCTAG AGGGTCGTGT 3600

TTTGGGATCC GAAGACAGAA CAGTGTGAAT AGTGGCATAC TCCTGCCAAT GAGCAAGGAC 3660

AGGATGGAGT TACAGAAGTC TCCCTCCACC TCCTGCCTCT ATGGGAAGAA ACTCTCCAAT 3720

GGCTCTATTG TGCCCCTAGA GGACAGCCTG AACCTCATTG AAGTGGCCAC AGAAGTGCCC 3780

AAGAGGAAAA CTGGCTATTT TGCTGCCCCC ACTCAGATGG AACCAGAGGA CCAGTTTGTT 3840

GTGCCTCGTG ACCTGGAAGA AGAAGTGAAG GAACAAATGA AACAGCACCA GGACAGCCGG 3900

CTCGAGCCTG AGCCCCTCGA AGAGGATAGG ACCGAGCCCC CGGAGGAGTT TGACACAGCA 3960

CTATGA 3966

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 783   SHGLAEMAGQRNKLCVSALAMDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  837

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 838   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtvdpas  887

         ***99....77888889************......89***************99999***

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 888   sfSLTVANVGTCQAVLCRGGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  945

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++s++lt +de liL+ + lw+++s  eav++vr+v +

Q: 946   CCTRMLGCTYLYPWILPKPHISSTPLTIQDELLILGNKALWEHLSYTEAVNAVRHVQD--  1003

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 1004  --PLAAAKKLCTLAQSYGCQDNVGAMVV  1029

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA MDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT VDPASSFSLT VANVGTCQAV 120

LCRGGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISSTPLT IQDELLILGN KALWEHLSYT EAVNAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>