EKS-NOL-00062

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00062

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	359.7	9.9E-108	192	469	278

Status

Unreviewed

Ensembl Protein

ENSNLEP00000007150

UniProt Accession

G1R1S8;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK17

Gene Synonyms/Alias

CDK17;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000005912	ENSNLEP00000007150	ENSNLET00000007505

Organism

Nomascus leucogenys

Functional Description

Protein Length

519

Protein Sequence
(FASTA)

MKKFKRRLSL TLRGSQTIDE SLSELAEQMT IEENSSKDNE PIVKNGRPPT SHSMHSFLHQ 60

YTGSFKKPPL RRPHSVIGGS LGSFMAMPRN GSRLDIVHEN LKMGSDGESD QASGTSSDEV 120

QSPTGVCLRN RIHRRISMED LNKRLSLPAD IRIPDGYLEK LQINSPPFDQ PMSRRSRRAS 180

LSEIGFGKME TYIKLEKLGE GTYATVYKGR SKLTENLVAL KEIRLEHEEG APCTAIREVS 240

LLKDLKHANI VTLHDIVHTD KSLTLVFEYL DKDLKQYMDD CGNIMSMHNV KLFLYQILRG 300

LAYCHRRKVL HRDLKPQNLL INEKGELKLA DFGLARAKSV PTKTYSNEVV TLWYRPPDVL 360

LGSSEYSTQI DMWGVGCIFF EMASGRPLFP GSTVEDELHL IFRLLGNRRN LFPKIVLSEK 420

FYQLREDKFS LFFVVSRLDS EGIELITKFL QYESKKRVSA EEAMKHVYFR SLGPRIHALP 480

ESVSIFSLKE IQLQKDPGFR NSSYPETGHG KNRRQSMLF 519

Nucleotide Sequence
(FASTA)

ATGAAAAAAT TTAAGAGAAG GCTATCCCTC ACACTCCGAG GAAGCCAGAC TATTGATGAA 60

TCATTGTCTG AATTGGCTGA ACAAATGACT ATTGAAGAAA ACAGCAGCAA GGATAATGAG 120

CCTATTGTGA AGAATGGCAG GCCTCCAACG TCTCACAGCA TGCATTCCTT CCTCCACCAG 180

TACACAGGAT CTTTCAAGAA GCCCCCATTG CGGAGACCAC ACAGTGTTAT TGGAGGGAGC 240

CTTGGCTCCT TCATGGCAAT GCCCAGAAAT GGAAGCAGAT TAGATATTGT TCATGAAAAT 300

CTAAAAATGG GATCAGATGG TGAGAGTGAC CAAGCTTCTG GGACATCATC TGATGAAGTC 360

CAGTCACCCA CAGGTGTTTG TCTCAGAAAT CGTATACATA GACGGATCTC AATGGAGGAT 420

TTAAATAAGC GGTTATCGCT GCCTGCAGAC ATCAGAATAC CTGATGGATA TCTTGAAAAG 480

TTGCAGATAA ACAGTCCACC ATTTGACCAA CCAATGAGTC GAAGGTCTCG TAGAGCTTCC 540

TTATCAGAAA TTGGCTTTGG AAAAATGGAA ACCTACATCA AATTGGAAAA GCTTGGAGAG 600

GGTACATATG CAACAGTATA TAAAGGAAGA AGTAAATTGA CAGAGAATTT GGTGGCATTA 660

AAAGAGATCC GATTGGAACA TGAAGAAGGT GCACCCTGCA CAGCTATAAG AGAAGTTTCA 720

CTATTAAAGG ATTTAAAACA TGCAAATATA GTAACCTTAC ATGACATTGT TCACACAGAT 780

AAATCCTTGA CTTTGGTGTT TGAGTATCTG GATAAAGACC TGAAACAGTA CATGGATGAC 840

TGTGGAAACA TCATGAGCAT GCACAATGTA AAGCTGTTTC TATACCAAAT TCTACGTGGT 900

TTGGCATATT GCCATAGAAG AAAGGTATTG CATCGAGACT TGAAACCACA GAACCTCCTC 960

ATTAATGAAA AAGGAGAATT AAAGCTAGCA GATTTTGGAC TAGCCCGAGC CAAGTCAGTT 1020

CCCACAAAGA CCTACTCAAA TGAAGTTGTC ACACTATGGT ACCGGCCACC TGATGTGCTT 1080

CTTGGTTCCT CGGAGTACTC AACACAGATT GACATGTGGG GTGTTGGTTG CATTTTCTTT 1140

GAAATGGCTT CTGGAAGACC TTTATTTCCA GGATCAACTG TGGAAGATGA ACTGCACTTA 1200

ATTTTCCGAC TGCTAGGTAA CAGAAGAAAT CTTTTCCCAA AAATAGTTTT ATCTGAAAAG 1260

TTTTATCAGC TAAGAGAGGA TAAATTTTCA TTGTTCTTTG TTGTTTCTAG GTTAGACTCT 1320

GAAGGAATTG AGTTGATAAC AAAATTTCTT CAGTATGAAT CTAAGAAAAG GGTTTCAGCT 1380

GAAGAGGCCA TGAAACATGT GTACTTTCGA AGTCTGGGAC CAAGAATACA TGCTTTACCA 1440

GAAAGTGTGT CAATATTCAG TTTGAAAGAG ATTCAGTTGC AAAAGGACCC GGGTTTTCGA 1500

AATTCTTCTT ATCCAGAGAC AGGACATGGG AAGAACAGAA GACAGAGCAT GCTCTTTTAA 1560

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y klek+geGty++vyk+++k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 192   YIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  250

         7799********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++v+ ++k+l+Lvfe+l++dLk++++++ +  +s+++vk +l+q+l+glay+H++k

Q: 251   VTLHDIVH-TDKSLTLVFEYLDKDLKQYMDDCGN-IMSMHNVKLFLYQILRGLAYCHRRK  308

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s+p+kty++evvTlwYr+P++Llg++eYst

Q: 309   VLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYST  368

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeykksfpk  240

         ++D+W+vgci+ e+++ +plf+g++  d+l+ if+llg+  ++ +p++   +++  ++++

Q: 369   QIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGNR-RNLFPKIVLSEKFY-QLRE  426

         **************************************86.57899999888876.4544

S: 241   kkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

           k +l  +v++l++++++l++k+l+++ kkR+sa+ea++h yf

Q: 427   -DKFSLFFVVSRLDSEGIELITKFLQYESKKRVSAEEAMKHVYF  469

         .4447778889********************************8

Domain Sequence
(FASTA)

YIKLEKLGEG TYATVYKGRS KLTENLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIVHTDK SLTLVFEYLD KDLKQYMDDC GNIMSMHNVK LFLYQILRGL AYCHRRKVLH 120

RDLKPQNLLI NEKGELKLAD FGLARAKSVP TKTYSNEVVT LWYRPPDVLL GSSEYSTQID 180

MWGVGCIFFE MASGRPLFPG STVEDELHLI FRLLGNRRNL FPKIVLSEKF YQLREDKFSL 240

FFVVSRLDSE GIELITKFLQ YESKKRVSAE EAMKHVYF 278

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013