EKS-NOL-00193

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00193

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	484.3	8.5E-146	4	286	283

Status

Unreviewed

Ensembl Protein

ENSNLEP00000009866

UniProt Accession

G1R9H8;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000008065	ENSNLEP00000009866	ENSNLET00000010344

Organism

Nomascus leucogenys

Functional Description

Protein Length

583

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKKTGQIV AIKIFYERPE RSVNKIAMRE IKFLKQFHHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIDYLHSNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTSYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVLKVGNL SPHLQNIFSK SPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PADRISSSDL LHHEYFTRDG FIEKFMPELK 300

AKLLQEAKVN LLMKPKESSK ENELRKDERK TVYTNTLLSS SVLGKEIEKE KKPKEIKVTV 360

IKVKGGRGDI SEPKKKEYEG GLGQQDANEN VHPMSPDTKL VTIEPPNPIN PSTNCNGLKE 420

NSHCGGSMTM PPINLTNSNL MAANLNSNLF HPSVRLTERA KKRRTSSQSI GQVMPNSRQE 480

DPGPIQSQME KGIFNERTGH SDQMANENKR KLNFSRSDRK EFHFPELPVT MQSKDTKGME 540

VKQIKMPKRE SKKTDSSKIS TLLNVDQNQE KQELKNSGLS SKM 583

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACCCT TGGAAAAGTG GGAGAGGGAA GTTACGGAAC AGTCATGAAA 60

TGTAAACATA AGAAGACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA GAGACCAGAA 120

CGATCTGTCA ACAAAATTGC GATGAGAGAA ATAAAGTTTC TAAAGCAATT TCATCACGAA 180

AACCTGGTCA ATCTGATTGA AGTTTTTAGA CAGAAAAAGA AAATTCATTT GGTATTTGAA 240

TTTATTGACC ACACAGTATT AGATGAGTTA CAACATTATT GTCATGGACT AGAGAGTAAA 300

CGACTTAGAA AATACCTCTT CCAGATCCTT CGAGCAATTG ACTATCTTCA CAGTAATAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTAT CCCAGTCAGG AATTACTAAG 420

CTCTGTGATT TTGGTTTTGC ACGAACACTA GCAGCTCCTG GGGACATTTA TACGGACTAT 480

GTGGCCACAC GCTGGTATAG AGCTCCAGAA TTAGTATTAA AAGATACTTC TTATGGAAAA 540

CCTGTGGATA TCTGGGCTTT GGGCTGTATG ATCATTGAGA TGGCCACTGG AAATCCCTAT 600

CTTCCTAGTA GTTCTGATTT GGATTTACTC CATAAAATTG TTTTGAAAGT GGGCAATTTG 660

TCACCTCACT TGCAGAATAT CTTTTCCAAG AGCCCCATTT TCGCTGGGGT AGTTCTTCCT 720

CAAGTTCAAC ACCCCAAAAA TGCAAGAAAA AAATATCCAA AGCTTAATGG ATTGTTGGCA 780

GATATAGTTC ATGCTTGTTT ACAAATTGAT CCTGCTGACA GGATATCATC TAGTGATCTT 840

TTGCATCATG AGTATTTTAC TAGAGATGGA TTTATTGAAA AATTCATGCC AGAACTGAAA 900

GCTAAATTAC TGCAGGAAGC AAAAGTCAAT TTATTAATGA AGCCAAAAGA GAGTTCTAAA 960

GAAAATGAAC TCAGGAAAGA TGAAAGAAAA ACAGTTTATA CCAATACACT GCTAAGTAGT 1020

TCAGTTTTGG GAAAGGAAAT AGAAAAAGAG AAAAAGCCCA AGGAGATCAA AGTCACAGTT 1080

ATTAAAGTCA AAGGAGGAAG AGGAGATATC TCAGAACCAA AAAAGAAAGA GTATGAAGGT 1140

GGACTTGGTC AACAGGATGC AAATGAAAAT GTTCATCCTA TGTCTCCAGA TACAAAACTT 1200

GTAACCATTG AACCACCAAA CCCTATCAAT CCCAGCACTA ACTGTAATGG CTTGAAAGAA 1260

AATTCACATT GCGGAGGTTC TATGACAATG CCACCCATCA ATCTAACCAA CAGTAATTTG 1320

ATGGCTGCAA ATCTCAATTC AAATCTCTTT CACCCCAGTG TGAGGTTAAC TGAAAGAGCA 1380

AAAAAGAGAC GCACTTCTTC ACAATCTATT GGGCAAGTTA TGCCTAATAG CAGGCAAGAG 1440

GATCCAGGTC CTATTCAAAG CCAAATGGAG AAGGGTATAT TTAATGAGCG AACAGGTCAC 1500

AGTGACCAAA TGGCAAATGA GAACAAAAGG AAGCTGAATT TTTCCAGATC TGACAGGAAA 1560

GAATTCCATT TTCCAGAATT GCCTGTCACA ATGCAGTCAA AAGATACAAA AGGAATGGAA 1620

GTTAAACAGA TAAAAATGCC GAAGAGGGAG TCAAAGAAAA CAGATTCATC TAAGATATCA 1680

ACTTTACTTA ACGTGGATCA AAATCAAGAA AAACAAGAGC TGAAAAATTC TGGATTATCC 1740

TCCAAGATGT AA 1752

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ ++v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKKTGQIVAIKIFYERPE-RSVNKIAMREIKFLKQFHHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+ai+++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+ifsk+++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpa+r+s+++ll+heyf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KKTGQIVAIK IFYERPERSV NKIAMREIKF LKQFHHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI DYLHSNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTSYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VLKVGNLSPH LQNIFSKSPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAD RISSSDLLHH EYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013