EKS-NOL-00357

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00357

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	335.2	3.1E-100	1061	1324	264

Status

Unreviewed

Ensembl Protein

ENSNLEP00000010345

UniProt Accession

G1RAU8;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000008465	ENSNLEP00000010345	ENSNLET00000010852

Organism

Nomascus leucogenys

Functional Description

Protein Length

1328

Protein Sequence
(FASTA)

MSSMPKPERH AESLLDICHD TNSSPTDMMT VTKNQNIILQ SISSSEEFNQ DGDCSHSTLV 60

NEVEDPSGGR QDWQPRTEGV EITVTFPRDA SPPQEMSQED LKEKNQITSS HQEWAQAHAV 120

LHPNETERVE LRTKTLTMRP LVLQKEERSR EFCNVNLGFL LPRSCSEPNI SKSVTREDAP 180

HFLKEQQRKS EEFSTSHMKY SGRSIEFLLP PLSLLPTRSG VLTIPQNHKF PKEKERNIPS 240

LTSFVPKLSV SFRQSDELSP SNKPPGALVK LLMDPTLRSS DGFIWSRNMC SFPKTNRHRQ 300

CLEMEENWKS KEIEECNKIE ITHFEKGQSL VSFENLKEGN IPADREEDID RHGSKTRKPE 360

EENSQYLSSR KNESSVAKNY EQDPEIVCTI PSKFQETQHS EITPSQDEEM RNNKAASKRA 420

SLHKNEAMEP NNILEEYTVL KCLSSVVFDD PIDKLSEGHS SMETNIKISI AERAKPEMNG 480

MVPLIHITFP VDGSPKEPAI AKPSLQKRKG TIHNNHSVNI PVHQENDKHK MNSHRSKLDS 540

KTKTSKKTPQ NFMISTEGPI KPTMLKTSRK TQIFPALGLV DPRPWQLPRF QKKMPQIAKK 600

QSTHQTQKPK KQSFPCICKN PGIQKSCVPL SVQPTEPRLN YLDLKYSDMF NEINSTANGP 660

GIYEMFGTPV YCHMRETERD ENKYYHEICS APSGRCITNK CRSSRSERKS NIRTRLSQKK 720

THMKPPKTSF GIKQEHKVLI SKEKSSKAIH SNLHDIENGD GISEPDWQIK SSGNEFLSSK 780

DEIHPMNLAQ TLEQSMKQNE FPPVSDLSIV EEVSMEESAG DRDISNNEIL TTSLRDLQEL 840

EELHHQIPFI PSENSWAVPS EKNSNKYVQQ EKQNIASLSK VNASRILTND LEFDSVSDQS 900

KTLTNFSFQE KQESASSQTY QYWVHYLDHD SLANKSITYQ MFRKTLSGTN SISQGILDSV 960

NNEELTDELL GCLAAELLAL DEKDNNSCQK MANETDPENL NLVLSRRGST PKEMGRETTK 1020

VKIQRHSSGL RIYDREEKFL ISNEKKIFSE NSLKSEEPIL WTKGEILGKG AYGTVYCGLT 1080

SQGQLIAVKQ VALDTSDKLA TEKEYRKLQE EVDLLKALKH VNIVAYLGTC LQENTVSIFM 1140

EFVPGGSISS IINRFGPLPE IVFCKYTKQI LQGVAFLHEN CVVHRDIKGN NVMLMPTGII 1200

KLIDFGCAKR LAWAGLNGTH SDMLKSMHGT PYWMAPEVIN ESGYGRKSDI WSIGCTVFEM 1260

ATGKTPLASM DRMAAMFYIG AHRGLMPPLP DHFSENAADF VRMCLTRDQH ERPSALQLLK 1320

HSFLERSH 1328

Nucleotide Sequence
(FASTA)

ATGAGTTCTA TGCCAAAACC AGAAAGACAT GCTGAGTCAT TGCTTGACAT TTGTCATGAT 60

ACAAACTCTT CTCCAACTGA TATGATGACA GTTACCAAAA ATCAAAACAT CATCTTGCAA 120

AGCATCAGCA GCAGTGAGGA GTTCAACCAA GATGGTGACT GCAGTCATTC CACACTGGTT 180

AATGAAGTAG AAGATCCCAG TGGTGGTAGA CAGGACTGGC AACCCAGGAC AGAAGGTGTT 240

GAGATCACTG TGACTTTTCC AAGAGATGCC AGTCCTCCCC AAGAAATGAG CCAAGAAGAC 300

TTAAAAGAAA AGAATCAGAT AACCTCATCA CATCAAGAAT GGGCACAAGC ACATGCAGTT 360

TTGCATCCAA ATGAAACAGA AAGAGTGGAG CTCAGGACAA AGACGCTGAC CATGCGGCCC 420

TTAGTTTTGC AAAAAGAGGA ACGTTCCAGG GAGTTCTGCA ATGTGAACTT GGGCTTTTTG 480

CTGCCAAGAT CTTGTTCAGA ACCAAACATT TCCAAGTCTG TAACCAGAGA AGATGCTCCT 540

CATTTTCTGA AGGAGCAGCA AAGAAAATCT GAAGAGTTTT CGACCTCTCA TATGAAGTAC 600

AGTGGCCGAA GCATCGAGTT CCTTCTGCCA CCACTGTCAC TCTTGCCCAC GCGATCTGGT 660

GTCCTTACTA TCCCCCAAAA TCACAAGTTT CCAAAGGAAA AAGAAAGAAA CATTCCAAGC 720

CTCACATCTT TTGTGCCTAA GCTCTCAGTC TCTTTTCGTC AATCTGATGA GCTTAGCCCA 780

TCAAACAAGC CTCCGGGAGC CCTAGTTAAG TTGTTGATGG ATCCGACTCT CAGGTCTTCT 840

GATGGCTTCA TTTGGTCAAG AAACATGTGC TCTTTTCCTA AGACTAACCG TCACAGACAA 900

TGCCTGGAGA TGGAGGAGAA CTGGAAATCC AAGGAAATAG AAGAATGTAA CAAAATTGAA 960

ATCACTCACT TTGAAAAAGG GCAGTCTTTG GTGTCTTTTG AGAATTTGAA GGAAGGCAAT 1020

ATTCCTGCAG ATAGGGAAGA GGATATTGAC CGCCATGGCA GTAAAACACG AAAACCTGAA 1080

GAAGAGAACT CTCAATATCT TTCATCGAGA AAGAATGAGA GTTCAGTAGC CAAAAACTAT 1140

GAACAAGATC CAGAAATAGT ATGTACCATT CCAAGCAAGT TCCAAGAAAC CCAGCATTCA 1200

GAAATAACTC CAAGCCAGGA TGAAGAGATG AGAAATAATA AAGCTGCTTC AAAAAGAGCT 1260

TCATTACATA AAAATGAAGC AATGGAACCA AACAATATTT TAGAAGAGTA TACTGTACTT 1320

AAATGCTTGT CCAGTGTAGT CTTTGATGAC CCCATTGATA AACTCTCAGA AGGTCATAGC 1380

AGCATGGAGA CAAACATAAA AATATCAATA GCAGAAAGAG CCAAACCAGA AATGAATGGG 1440

ATGGTGCCTC TTATCCACAT CACCTTCCCC GTGGATGGAA GCCCCAAGGA ACCAGCGATA 1500

GCCAAACCAA GCCTCCAAAA AAGAAAGGGA ACCATTCATA ACAACCATAG TGTCAACATA 1560

CCTGTACACC AAGAAAATGA CAAGCATAAG ATGAATTCCC ATAGGAGCAA GTTGGATTCA 1620

AAGACCAAGA CAAGTAAGAA GACACCTCAG AATTTCATGA TTTCTACTGA AGGTCCCATT 1680

AAGCCTACCA TGCTTAAAAC CAGCAGAAAG ACACAAATTT TCCCGGCTTT GGGACTTGTT 1740

GACCCCAGGC CTTGGCAATT GCCCAGGTTT CAAAAGAAAA TGCCACAGAT AGCAAAGAAG 1800

CAATCAACTC ACCAGACCCA GAAACCTAAA AAGCAATCAT TTCCTTGCAT CTGTAAAAAT 1860

CCAGGAATAC AAAAGTCATG TGTTCCTCTC TCTGTTCAAC CGACAGAGCC AAGACTAAAT 1920

TACCTAGATC TTAAGTATAG TGATATGTTC AATGAAATCA ATTCAACTGC TAATGGACCT 1980

GGAATCTATG AAATGTTTGG GACCCCTGTT TATTGTCATA TGCGAGAGAC TGAAAGGGAT 2040

GAAAACAAAT ATTACCATGA GATATGTTCG GCTCCATCAG GCAGATGTAT CACCAATAAA 2100

TGTCGATCTT CACGCAGTGA GAGGAAGAGC AATATTAGAA CAAGACTTTC TCAGAAAAAA 2160

ACACATATGA AACCCCCAAA GACTTCATTT GGCATTAAAC AAGAGCACAA AGTCTTGATT 2220

TCTAAAGAAA AGAGTTCCAA GGCTATACAT AGCAACCTAC ATGACATTGA AAATGGTGAT 2280

GGTATTTCAG AACCAGACTG GCAGATAAAG TCTTCAGGAA ATGAGTTTCT ATCTTCCAAA 2340

GATGAAATTC ATCCCATGAA CTTGGCTCAG ACACTTGAGC AGTCCATGAA ACAGAATGAA 2400

TTCCCTCCTG TCTCAGATTT ATCCATTGTT GAAGAAGTTT CTATGGAAGA GTCTGCTGGT 2460

GATAGAGACA TTTCTAACAA TGAAATACTC ACCACAAGCC TCAGAGATCT GCAAGAACTT 2520

GAAGAGCTAC ATCACCAGAT CCCATTTATC CCTTCAGAAA ACAGCTGGGC AGTGCCCAGT 2580

GAGAAGAATT CTAACAAGTA TGTACAGCAA GAAAAGCAGA ATATAGCATC TCTTAGTAAA 2640

GTAAATGCCA GCCGAATTTT AACTAATGAT CTAGAGTTTG ATAGTGTTTC AGATCAGTCT 2700

AAAACACTTA CAAATTTCTC TTTCCAAGAA AAACAAGAAA GTGCATCTTC CCAGACATAT 2760

CAATATTGGG TACATTATTT GGATCATGAT AGTTTAGCAA ATAAGTCAAT CACATATCAA 2820

ATGTTTAGAA AAACCTTAAG TGGCACAAAT TCAATTTCCC AAGGAATTCT GGACTCTGTA 2880

AATAATGAAG AATTGACAGA TGAACTATTA GGTTGTCTAG CTGCAGAATT ATTAGCTCTT 2940

GATGAGAAAG ATAACAACTC TTGCCAAAAA ATGGCAAATG AAACAGATCC TGAAAACCTA 3000

AATCTTGTCC TCAGTCGGAG AGGAAGTACC CCAAAAGAAA TGGGCAGAGA GACAACAAAA 3060

GTCAAAATAC AGAGGCATAG TAGTGGGCTC AGGATATATG ACAGGGAGGA GAAATTTCTC 3120

ATCTCAAATG AAAAGAAGAT ATTTTCTGAA AATAGTTTAA AGTCTGAAGA ACCTATCCTA 3180

TGGACCAAGG GTGAGATTCT TGGAAAGGGA GCCTACGGCA CAGTATACTG TGGTCTCACT 3240

AGCCAAGGGC AGCTAATAGC TGTAAAACAG GTGGCTTTGG ATACCTCTGA TAAATTAGCT 3300

ACTGAAAAGG AATACCGGAA ACTACAGGAA GAAGTAGATT TGCTCAAAGC ACTGAAACAT 3360

GTCAACATTG TGGCCTATTT GGGGACATGC TTGCAAGAGA ACACTGTAAG CATTTTCATG 3420

GAGTTTGTTC CTGGTGGCTC AATCTCTAGT ATTATAAACC GTTTTGGGCC ATTGCCTGAG 3480

ATAGTGTTCT GTAAATATAC GAAACAAATT CTGCAAGGTG TTGCTTTCCT TCATGAGAAC 3540

TGTGTGGTAC ATCGCGATAT CAAAGGAAAT AATGTTATGC TCATGCCAAC TGGAATAATA 3600

AAGCTGATTG ACTTTGGCTG TGCCAAGCGT TTGGCCTGGG CAGGTTTAAA TGGCACCCAC 3660

AGTGACATGC TTAAGTCCAT GCATGGGACT CCATATTGGA TGGCCCCAGA AGTCATCAAT 3720

GAGTCTGGCT ATGGACGGAA ATCAGATATC TGGAGCATTG GTTGTACTGT GTTTGAGATG 3780

GCTACAGGGA AGACTCCACT GGCTTCCATG GACAGGATGG CCGCCATGTT TTACATCGGA 3840

GCACACCGAG GGCTGATGCC TCCTTTACCA GACCACTTCT CAGAAAATGC AGCAGACTTT 3900

GTGCGCATGT GCCTGACCAG GGACCAGCAT GAGCGACCTT CTGCTCTTCA GCTCCTGAAG 3960

CACTCCTTCT TGGAGAGAAG TCACTGA 3987

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++g+l+avK+v++++ +k +++ke+++l+eE++llk+lk

Q: 1061  WTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTsDKLATEKEYRKLQEEVDLLKALK  1119

         89*****************8.89***********8614556778****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv y+G++ +e++++if+E+v+gGs+ss+++++g+l e v++kytkqil+g+a+LHe

Q: 1120  HVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEIVFCKYTKQILQGVAFLHE  1179

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 1180  NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHsdmLKSMHGTPYWMAPEVI  1239

         **********************************999988877899**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk P a++ +++a+mf +ga++  +P++p+++se+

Q: 1240  NES--GYGRKSDIWSIGCTVFEMATGKTPLASM-DRMAAMFYIGAHRgLMPPLPDHFSEN  1296

         988..****************************.9**********9979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LLkh+fl

Q: 1297  AADFVRMCLTRDQHERPSALQLLKHSFL  1324

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGQLIAVKQ VALDTSDKLA TEKEYRKLQE EVDLLKALKH 60

VNIVAYLGTC LQENTVSIFM EFVPGGSISS IINRFGPLPE IVFCKYTKQI LQGVAFLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGLNGTH SDMLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSIGCTVFEM ATGKTPLASM DRMAAMFYIG AHRGLMPPLP DHFSENAADF 240

VRMCLTRDQH ERPSALQLLK HSFL 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013