EPS-NOL-00026

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00026

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	210.1	4.7E-62	1167	1412	246

Status

Unreviewed

Ensembl Protein

ENSNLEP00000010575

UniProt Accession

G1RBH8;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000008641	ENSNLEP00000010575	ENSNLET00000011091

Organism

Nomascus leucogenys

Functional Description

Protein Length

1710

Protein Sequence
(FASTA)

MEPAAAATAQ RLPEPGKEDR ASAPAAAAAA LAAAAGGGRS PEPALTPAAP SGGNGSGGGA 60

REEAPGEAPP GPLPGRAGGA GRRRRRGAPQ PIAGGAAPVP GAGGGANSLM LRRGRLKRNL 120

SAAAAAASSS SSSSSSAVAA SHSPGAAGLP ASCSASASLC TRSLDRKTLL LKHRQTLQLQ 180

PSDRDWVRHE LQRGCVHVFD RHMASTYLRP VLCTLDTTAG EVAARLLQLG HKGGGVVKVL 240

GQGSGATTAW EPAEPLPEAG PRLAPPEPRD SEAPPARSAP GAVGGPPRAP PADLPLPACG 300

PGGWSHRSSP APSDSSPCEP FVGGPASSPR ASRPVASDTE SFSLSPSAES VSDRLDPYSS 360

GGGSSSSSEE LEADTASAPT GVPGQPRRPG HPAQPLPPPQ TASSPRPQQK APRAIDSPGG 420

AVREGSCEEK AAAAVAPGGL QSTPGRSGVT AEKAPPPPPP PTLYVQLHGE TTRRLEAEEK 480

PLQIQNDYLF QLGFGELWRV QEEGMDSEIG CLIRFYAGKP HSTGSSERIQ LSGMYNVRKG 540

KMQLPVNRWT RRQVILCGTC LIVSSVKDSL TGKMHVLPLI GGKVEEVKKH QHCLAFSSSG 600

PQSQTYYICF DTFTEYLRWL RQVSKVASQR ISSVDLSCCS LEHLPANLFY SQDLTHLNLK 660

QNFLRQNPSL PAARGLNELQ RFTKLKSLNL SNNHLGDFPL AVCSIPTLAE LNVSCNALRS 720

VPAAVGVMHN LQTFLLDGNF LQSLPAELEN MKQLSYLGLS FNEFTDIPEV LEKLTAVDKL 780

CMSGNCMETL RLQALRKMPH IKHVDLRLNV IRKVIADEVD FLQHVTQLDL RDNKLGDLDA 840

MIFNNIEVLH CERNQLVTLD ICGYFLKALY ASSNELVQLD VYPVPNYLSY MDVSRNRLEN 900

VPEWVCESRK LEVLDIGHNQ ICELPARLFC NSSLRKLLAG HNQLARLPER LERTLVEVLD 960

VQHNQLLELP PNLLMKADSL RFLNASANKL ESLPPATLSE ETNSILQELY LTNNSLTDKC 1020

VPLLTGHPHL KILHMAYNRL QSFPASKMAK LEELEEIDLS GNKLKAIPTT IMNCRRMHTM 1080

IAHSNCIEVF PEVMQLPEIK CVDLSCNELS EVTLPENLPP KLQELDLTGN PRLVLDHKTL 1140

ELLNNIRCFK IDQPSTGDAS GAPAVWSHGY TEASGVKNKL CVAALSVNNF CDNREALYGV 1200

FDGDRNVEVP YLLQCTMSDI LAEELQKTKN EEEYMVNTFI VMQRKLGTAG QKLGGAAVLC 1260

HIKHDPVDPG GSFTLTSANV GKCQTVLCRN GKPLPLSRSY IMSCEEELKR IKQHKAIITE 1320

DGKVNGVTES TRILGYTFLH PSVVPRPHVQ SVLLTPQDEF FILGSKGLWD SLSVEEAVEA 1380

VRNVPDALAA AKKLCTLAQS YGCHDSISAV VVQLSVTEDS FCCCELSAGG AVPPPSPGIF 1440

PPSVNVVIKD RPSDGLGVPS SSSGMASEIS SELSTSEMSS EVGSTASDEP PPGALSENSP 1500

AYPSEQRCML HPICLSNSFQ RQLSSATFSS AFSDNGLDSD DEEPIEGVFT NGSRVEVEVD 1560

IHCSRAKEKE KQQHLLQVPA EASDEGIVIS ANEDEPGLPR KADFSAVGTI GRRRANGSVA 1620

PQERSHNVIE VATDAPLRKP GGYFAAPAQP DPDDQFIIPP ELEEEVKELM KHHQEQQQQQ 1680

QQPPPPPQLQ PQLPRHYQLD QLPDYYDTPL 1710

Nucleotide Sequence
(FASTA)

ATGGAGCCCG CCGCCGCGGC CACGGCGCAG CGACTCCCCG AGCCCGGCAA GGAGGACCGA 60

GCTTCGGCTC CGGCGGCAGC CGCGGCGGCT CTGGCGGCGG CGGCCGGGGG CGGCCGGAGT 120

CCGGAGCCCG CGCTGACCCC GGCGGCCCCG AGCGGCGGGA ACGGCAGCGG CGGCGGGGCG 180

CGGGAAGAGG CCCCGGGCGA GGCGCCGCCG GGGCCGCTGC CGGGCAGAGC AGGGGGTGCC 240

GGGCGCAGGA GGCGGCGCGG AGCGCCCCAG CCCATTGCCG GCGGGGCTGC CCCCGTACCC 300

GGGGCCGGCG GCGGCGCCAA CTCCCTCATG CTGAGGAGAG GGCGGCTGAA GAGGAATCTG 360

TCCGCGGCCG CCGCGGCCGC CTCGTCGTCG TCGTCGTCGT CGTCCTCGGC CGTTGCTGCC 420

TCGCACTCCC CCGGCGCTGC CGGCCTCCCC GCCTCCTGCT CGGCCTCGGC GTCGCTGTGC 480

ACCCGGAGCC TGGACAGGAA GACGCTGCTC CTGAAGCACC GGCAGACGCT GCAGCTGCAG 540

CCGTCGGACC GGGACTGGGT GAGGCACGAG CTCCAGCGCG GCTGCGTGCA CGTCTTCGAC 600

CGCCACATGG CCTCGACCTA CCTGCGCCCG GTGCTCTGCA CACTGGACAC CACGGCCGGC 660

GAGGTGGCCG CCCGCCTGCT GCAGCTGGGC CACAAAGGCG GCGGCGTGGT GAAGGTGCTG 720

GGCCAGGGGT CCGGAGCCAC CACCGCCTGG GAGCCCGCTG AGCCGCTCCC CGAGGCCGGT 780

CCCCGGCTCG CGCCCCCGGA GCCGCGGGAC TCGGAGGCAC CGCCCGCGAG GAGCGCGCCG 840

GGTGCCGTCG GGGGTCCTCC GCGCGCGCCC CCCGCCGACC TACCCCTGCC CGCCTGCGGC 900

CCGGGTGGGT GGTCGCACCG CTCCAGCCCA GCGCCCTCGG ACTCCAGCCC CTGCGAGCCG 960

TTCGTTGGGG GTCCTGCCTC TTCGCCCCGC GCCTCGCGGC CTGTGGCCTC CGACACCGAG 1020

AGCTTCAGCC TGAGTCCCAG CGCCGAGAGC GTGTCTGACC GGCTGGACCC CTACAGCAGC 1080

GGCGGTGGCT CCTCGTCGTC GTCGGAAGAG CTCGAGGCCG ACACAGCCTC GGCCCCGACG 1140

GGGGTCCCAG GCCAGCCCCG CCGTCCCGGC CACCCCGCGC AGCCCCTCCC GCCTCCCCAG 1200

ACGGCCTCCT CGCCTCGGCC GCAGCAGAAA GCCCCGAGGG CCATTGACAG CCCGGGCGGG 1260

GCCGTCCGCG AGGGGTCGTG CGAGGAGAAG GCGGCGGCAG CCGTGGCCCC GGGAGGCCTC 1320

CAGTCGACCC CCGGGAGGAG CGGGGTGACC GCGGAGAAAG CGCCTCCGCC GCCCCCGCCG 1380

CCCACTCTGT ACGTGCAGCT CCACGGAGAG ACCACCCGGC GCTTGGAGGC GGAGGAGAAG 1440

CCATTGCAGA TCCAAAATGA CTACCTCTTC CAACTGGGAT TTGGGGAGCT GTGGAGGGTG 1500

CAGGAGGAAG GCATGGACTC GGAGATTGGC TGCCTCATCC GTTTCTATGC AGGAAAACCT 1560

CACAGCACGG GTAGCTCTGA ACGAATTCAG CTCTCAGGAA TGTATAATGT CCGTAAAGGC 1620

AAGATGCAGT TGCCAGTGAA CCGATGGACA AGACGCCAAG TCATCCTATG TGGGACCTGC 1680

CTGATAGTAT CATCTGTGAA AGACAGCTTG ACCGGAAAGA TGCATGTTCT GCCACTAATT 1740

GGCGGAAAAG TAGAAGAAGT GAAAAAGCAC CAACACTGTT TAGCATTTAG CTCCTCTGGA 1800

CCCCAAAGCC AGACTTACTA CATTTGCTTT GATACTTTCA CAGAATACTT AAGGTGGCTG 1860

CGACAAGTCT CCAAGGTTGC ATCCCAGCGC ATTAGCTCAG TGGACCTCTC GTGTTGTAGC 1920

CTGGAACATC TGCCTGCCAA CCTCTTCTAC AGCCAAGACC TCACTCATCT TAATTTAAAA 1980

CAAAACTTCC TAAGGCAAAA CCCTAGCCTT CCAGCTGCCA GGGGGCTTAA TGAACTGCAA 2040

AGGTTCACCA AGTTGAAGAG TCTTAACCTT TCCAATAATC ATTTAGGGGA CTTCCCACTA 2100

GCAGTCTGCA GTATTCCAAC CCTGGCAGAG CTGAACGTGT CCTGCAATGC CCTGCGATCA 2160

GTCCCGGCAG CCGTTGGAGT GATGCACAAC TTACAGACAT TTTTGTTGGA TGGAAACTTT 2220

CTCCAATCCC TTCCTGCTGA GTTGGAGAAC ATGAAGCAGC TTAGTTATCT GGGTCTTTCT 2280

TTCAATGAAT TTACTGACAT TCCTGAAGTA TTGGAGAAAT TGACTGCTGT GGATAAACTT 2340

TGTATGTCCG GAAACTGTAT GGAGACCCTT AGGCTACAGG CTTTAAGAAA AATGCCTCAC 2400

ATTAAACATG TGGATCTAAG GTTGAACGTA ATTAGGAAGG TGATAGCAGA TGAAGTGGAC 2460

TTTCTACAGC ATGTTACTCA GCTTGACTTA CGAGACAATA AGCTTGGTGA TCTAGATGCC 2520

ATGATTTTCA ACAACATTGA AGTTTTACAC TGTGAAAGGA ATCAACTGGT CACATTAGAC 2580

ATCTGTGGCT ATTTCCTAAA AGCACTCTAT GCCTCTTCTA ATGAACTTGT TCAACTTGAT 2640

GTTTATCCAG TTCCAAATTA TCTGTCCTAC ATGGATGTTT CAAGGAACCG CTTAGAAAAT 2700

GTGCCTGAGT GGGTATGTGA AAGTCGAAAG CTAGAAGTTT TGGATATTGG CCATAATCAA 2760

ATATGTGAAC TTCCTGCCCG CTTATTTTGT AATAGCAGTC TCCGGAAACT ACTGGCAGGA 2820

CACAACCAGT TGGCAAGGCT GCCTGAAAGG CTAGAAAGAA CCTTGGTGGA GGTCTTGGAT 2880

GTGCAACACA ACCAGCTCCT TGAGCTCCCG CCTAACCTTC TGATGAAGGC TGACAGCCTG 2940

AGATTCCTGA ACGCATCTGC AAACAAACTG GAAAGCCTTC CTCCAGCCAC ACTTTCCGAA 3000

GAGACAAACA GTATCTTACA AGAGTTGTAT TTGACAAATA ACAGCCTCAC AGACAAATGT 3060

GTGCCCTTGT TAACGGGACA CCCCCATTTG AAGATCCTTC ACATGGCCTA TAACCGACTT 3120

CAGAGTTTTC CAGCAAGTAA AATGGCGAAA CTGGAGGAAC TTGAAGAAAT TGATCTCAGT 3180

GGGAATAAGC TGAAAGCCAT CCCAACAACG ATCATGAATT GCAGGCGCAT GCACACCATG 3240

ATTGCTCACT CCAACTGCAT CGAGGTCTTT CCCGAAGTTA TGCAGCTCCC AGAGATCAAG 3300

TGTGTGGACC TGAGCTGTAA TGAGCTAAGT GAAGTCACAT TACCAGAAAA CCTGCCTCCC 3360

AAACTGCAGG AGCTAGACCT GACTGGAAAC CCTCGCCTTG TCCTTGATCA CAAAACCCTG 3420

GAACTACTGA ATAATATCCG CTGTTTCAAG ATTGATCAGC CTTCTACAGG AGACGCTTCC 3480

GGAGCCCCAG CTGTATGGAG TCATGGTTAC ACTGAAGCTT CAGGGGTAAA AAACAAGTTG 3540

TGTGTCGCAG CCCTGTCGGT GAATAACTTC TGTGACAACC GCGAAGCCCT GTATGGTGTG 3600

TTTGATGGAG ACCGGAATGT GGAGGTGCCC TACCTTCTCC AGTGCACCAT GAGTGACATT 3660

TTGGCTGAAG AGCTGCAAAA AACAAAAAAT GAGGAAGAAT ACATGGTCAA TACATTCATT 3720

GTCATGCAAA GGAAACTTGG AACTGCTGGG CAGAAGCTTG GTGGTGCCGC TGTCCTTTGT 3780

CATATCAAGC ATGACCCTGT GGACCCAGGA GGATCCTTCA CCTTGACCTC TGCTAATGTG 3840

GGCAAGTGCC AAACAGTTCT CTGTCGAAAT GGAAAGCCGC TGCCTCTGTC CAGATCTTAC 3900

ATCATGAGCT GTGAAGAAGA GCTGAAGAGG ATTAAACAGC ACAAGGCCAT TATCACTGAG 3960

GATGGCAAGG TGAACGGAGT GACTGAGTCC ACGCGCATCC TGGGCTACAC CTTCCTCCAT 4020

CCCAGTGTGG TGCCTCGCCC CCACGTGCAG TCCGTGCTCC TGACCCCCCA GGATGAGTTC 4080

TTCATTCTAG GGAGTAAGGG GTTATGGGAC AGCCTGTCCG TCGAGGAGGC CGTGGAGGCC 4140

GTGCGCAACG TGCCCGATGC CCTGGCTGCT GCCAAGAAGC TGTGTACCCT GGCCCAGAGC 4200

TACGGCTGCC ATGACAGCAT CAGCGCTGTG GTGGTGCAGC TCAGTGTCAC TGAGGACAGC 4260

TTCTGTTGCT GTGAGCTCAG CGCCGGTGGG GCTGTGCCAC CACCCAGCCC TGGCATCTTC 4320

CCTCCCTCGG TGAACGTGGT GATCAAGGAT CGGCCCTCAG ATGGGCTAGG CGTGCCGTCC 4380

TCCAGCAGCG GCATGGCTTC CGAGATCAGC AGTGAGCTCT CCACTTCCGA GATGAGCAGT 4440

GAGGTGGGGT CAACAGCCTC CGATGAGCCC CCGCCCGGAG CCCTAAGCGA GAACAGCCCT 4500

GCCTACCCCA GTGAGCAGCG CTGCATGCTC CACCCCATCT GTCTGTCCAA CTCCTTCCAG 4560

CGCCAGCTAT CCAGCGCCAC ATTCTCTAGC GCCTTCTCTG ACAACGGCCT TGACAGTGAC 4620

GATGAGGAGC CCATCGAGGG CGTCTTCACC AATGGCAGCC GGGTGGAGGT GGAGGTGGAC 4680

ATCCACTGCA GCCGGGCCAA GGAGAAGGAG AAACAGCAGC ACCTGCTTCA GGTGCCAGCA 4740

GAGGCCAGCG ATGAGGGCAT TGTCATTAGC GCCAACGAGG ATGAGCCAGG TCTGCCCAGG 4800

AAGGCAGACT TCTCTGCTGT TGGGACCATT GGGCGCCGGA GGGCCAATGG CTCTGTTGCG 4860

CCCCAGGAAA GGAGCCACAA TGTGATAGAG GTGGCTACAG ACGCGCCTCT TCGAAAGCCT 4920

GGAGGCTATT TTGCTGCCCC GGCTCAGCCG GATCCCGATG ATCAGTTTAT CATACCCCCG 4980

GAGCTGGAAG AGGAGGTCAA AGAACTCATG AAGCATCACC AGGAGCAACA GCAGCAGCAG 5040

CAGCAGCCGC CGCCACCACC TCAGCTCCAG CCGCAGCTGC CGCGGCACTA CCAGCTGGAC 5100

CAGCTGCCAG ATTATTACGA CACGCCACTA TGA 5133

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 1167  SHGYTEASGVKNKLCVAALSVNNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  1221

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 1222  AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGAAVLCHIKHDpvdpgg  1271

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 1272  sfTLTSANVGKCQTVLCRNGKPLPLSRSYIMSCEEELKRIKQHKAIITEDG--KVNGVTE  1329

         *99*****************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s+ lt++def+iL+s+Glwd +s eeav++vr+v +

Q: 1330  STRILGYTFLHPSVVPRPHVQSVLLTPQDEFFILGSKGLWDSLSVEEAVEAVRNVPD---  1386

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 1387  -ALAAAKKLCTLAQSYGCHDSISAVVV  1412

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS VNNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGA AVLCHIKHDP VDPGGSFTLT SANVGKCQTV 120

LCRNGKPLPL SRSYIMSCEE ELKRIKQHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVLLTP QDEFFILGSK GLWDSLSVEE AVEAVRNVPD ALAAAKKLCT LAQSYGCHDS 240

ISAVVV 246

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>