EKS-NOL-00238

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00238

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/PDK1	422.8	5.9E-127	53	313	261

Status

Unreviewed

Ensembl Protein

ENSNLEP00000011477

UniProt Accession

G1RE27;

Protein Name

Protein Synonyms/Alias

Gene Name

ENSG00000205918

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000009438	ENSNLEP00000011477	ENSNLET00000012041

Organism

Nomascus leucogenys

Functional Description

Protein Length

386

Protein Sequence
(FASTA)

MVRTQTESST APGIPGGSTQ GPAMDGTASE PQPGAGSLQH PLPQPQKKRP EDFKFGKILG 60

EGSFSTVVLA RELATSREYA IKILEKRHII KENKVPYVTR ERDVMSRLDH PFFVKLYFTF 120

QDDEKLYFGL SYAKNGELLK YIRKIGSFDE TCTRFYTAEI VSALEYLHGK GIIHRDLKPE 180

NILLNEDMHI QITDFGTAEV LSPESKQARA NSFVGTAQYV SPELLTEKSA CKSSDLWALG 240

CIIYQLVAGL PPFRAGNEYL IFQKIIKLEY DFPEKFFPKA RDLVEKLLVL DATKRLGCEE 300

MEGYGPLKAH PFFESVTWEN LHQQTPPKLT AYLPAMSEDD EDCYGNVSWP GWRARRVLHA 360

RAPDPRVICS RKGRVSLPVR QACWWL 386

Nucleotide Sequence
(FASTA)

ATGGTGAGGA CCCAGACTGA GTCCAGCACA GCCCCTGGCA TTCCTGGTGG CAGCACGCAG 60

GGCCCCGCCA TGGACGGCAC TGCATCTGAG CCTCAGCCCG GCGCCGGCTC CCTGCAGCAC 120

CCACTGCCGC AGCCTCAGAA GAAGCGGCCT GAGGACTTCA AGTTTGGGAA AATTCTTGGG 180

GAAGGCTCTT TTTCCACGGT TGTCCTGGCT CGAGAACTGG CAACCTCCAG AGAATATGCG 240

ATTAAAATTC TGGAGAAGCG ACATATCATA AAAGAGAACA AGGTCCCGTA TGTAACCAGA 300

GAGCGGGATG TCATGTCGCG CCTGGATCAC CCCTTCTTTG TTAAGCTTTA CTTCACATTT 360

CAGGACGACG AGAAGCTGTA TTTCGGCCTT AGTTATGCCA AAAACGGAGA ACTACTCAAA 420

TATATTCGCA AAATCGGTTC ATTCGATGAG ACCTGTACCC GATTTTACAC GGCCGAGATT 480

GTGTCTGCTT TAGAGTACTT GCACGGCAAG GGCATCATTC ACAGGGACCT TAAACCGGAA 540

AACATTTTGT TAAATGAAGA TATGCACATC CAGATCACAG ATTTTGGAAC AGCAGAAGTC 600

TTATCCCCAG AGAGCAAACA AGCCAGGGCC AACTCATTTG TGGGAACAGC GCAGTACGTT 660

TCTCCAGAGC TGCTCACGGA GAAGTCCGCC TGTAAGAGTT CAGACCTTTG GGCTCTTGGA 720

TGCATAATAT ACCAGCTTGT GGCAGGACTC CCACCATTCC GAGCTGGAAA CGAGTATCTT 780

ATATTTCAGA AGATCATTAA GTTGGAGTAT GACTTTCCAG AAAAATTCTT CCCTAAGGCA 840

AGAGACCTCG TGGAGAAACT TTTGGTTTTA GACGCCACAA AGCGGTTAGG CTGTGAGGAA 900

ATGGAAGGGT ACGGACCTCT TAAAGCACAC CCGTTCTTCG AGTCCGTCAC GTGGGAGAAC 960

CTGCACCAGC AGACGCCTCC GAAGCTCACC GCTTACCTGC CGGCCATGTC GGAAGACGAC 1020

GAGGACTGCT ATGGCAATGT AAGCTGGCCG GGATGGCGGG CGAGGCGGGT GCTTCATGCC 1080

CGTGCGCCAG ACCCACGTGT GATTTGTAGC CGAAAGGGGA GGGTGTCTCT GCCAGTGCGG 1140

CAGGCCTGTT GGTGGTTG 1158

Domain Profile

S: 1     fkfekelgeGsystvvlarekeskkeyaikvlekryiikekkvkyvtrekevlaklnehp  60

         fkf+k+lgeGs+stvvlare+++++eyaik+lekr+iike+kv+yvtre++v+++l +hp

Q: 53    FKFGKILGEGSFSTVVLARELATSREYAIKILEKRHIIKENKVPYVTRERDVMSRL-DHP  111

         89******************************************************.9**

S: 61    givkLyatfqDeeslyfvleyakkGdllellkkvgsfdeactryyaaellsaleflhkkg  120

         ++vkLy+tfqD+e+lyf l+yak+G+ll++++k+gsfde+ctr+y+ae++sale+lh kg

Q: 112   FFVKLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDETCTRFYTAEIVSALEYLHGKG  171

         ************************************************************

S: 121   iihrDlkpeniLldkdgkilitDfGsakvlepklkedskkeeeesarsksfvGtaeyvsP  180

         iihrDlkpeniLl++d++i+itDfG+a+vl+p++k+         ar++sfvGta+yvsP

Q: 172   IIHRDLKPENILLNEDMHIQITDFGTAEVLSPESKQ---------ARANSFVGTAQYVSP  222

         ******************************999998.........9**************

S: 181   elLtdsevskssDlWalgcilyqllaGkpPfraeneylifkkilkleyafpegfpekakd  240

         elLt+++++kssDlWalgci+yql+aG+pPfra neylif+ki+kley+fpe+f++ka+d

Q: 223   ELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEYDFPEKFFPKARD  282

         ************************************************************

S: 241   lveklLvkdakerltlee......ikahkff  265

         lveklLv da++rl++ee      +kah+ff

Q: 283   LVEKLLVLDATKRLGCEEmegygpLKAHPFF  313

         ******************************9

Domain Sequence
(FASTA)

FKFGKILGEG SFSTVVLARE LATSREYAIK ILEKRHIIKE NKVPYVTRER DVMSRLDHPF 60

FVKLYFTFQD DEKLYFGLSY AKNGELLKYI RKIGSFDETC TRFYTAEIVS ALEYLHGKGI 120

IHRDLKPENI LLNEDMHIQI TDFGTAEVLS PESKQARANS FVGTAQYVSP ELLTEKSACK 180

SSDLWALGCI IYQLVAGLPP FRAGNEYLIF QKIIKLEYDF PEKFFPKARD LVEKLLVLDA 240

TKRLGCEEME GYGPLKAHPF F 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013