EPS-NOL-00045

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00045

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPP/PP7	610.1	6.9E-184	119	453	335

Status

Unreviewed

Ensembl Protein

ENSNLEP00000011832

UniProt Accession

G1RF32;

Protein Name

Serine/threonine-protein phosphatase

Protein Synonyms/Alias

Gene Name

PPEF1

Gene Synonyms/Alias

PPEF1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000009696	ENSNLEP00000011832	ENSNLET00000012414

Organism

Nomascus leucogenys

Functional Description

Protein Length

651

Protein Sequence
(FASTA)

MGCSSSSVKT RRSETSLRAA LIIQNWYRGY KARLKARQHY ALTIFQSIEY ADEQSQMQLS 60

TFFSFMLENY THKEELELRN QSLESEQDMR DRRDYVDLID VPDSYNGPRL QFPLTCTDID 120

LLLEAFKEQQ ILHAHYVLEV LFETKKLLKQ MPNFTHIQTS PSKEVTICGD LHGKLDDLFL 180

IFYKNGLPSE RNPYVFNGDF VDRGRNSIEI LMILCVSFLV YPNDLHLNRG NHEDFMMNLR 240

YGFTKEILHK YKLHGKRILQ ILEELYAWLP IGTIIDDEVL VIHGGISETT DLNLLHRVER 300

NKMKSVLIPP TETSRDHDTD SKHNKVGVTF NAHGRIKTNG SPIEHLTKRE WEQIIDILWS 360

DPRGKNGCFP NTGRGGGCYF GPDVTSKILN KYQLKMLIRS HECKPEGYEI CHDGKVVTIF 420

SASNYYEEGS NRGAYIKLCS GTTPRFFQYQ VTKATCFQPL RQRVHTMENS AIKILRERVI 480

SRKSDLTRAF QLQDHRKSGK LSVSQWAFCM ENILGLNLPW RSLSSNLVNI DQNGNVEYMS 540

SFQNIHIEKP VQEAHSTLVE TLYRYRSDLE IIFNAIDTDH SGLISMEEFR AMWKLFSSHY 600

SVLIDDSQVN KLANIMDLNK DGSIDFNEFL KAFYVVHRYG DLMKPDVSNL G 651

Nucleotide Sequence
(FASTA)

ATGGGATGCA GCAGTTCTTC AGTGAAAACC AGGAGATCTG AGACATCGCT GAGAGCTGCG 60

TTGATCATCC AGAACTGGTA CCGAGGTTAC AAAGCTCGAC TGAAGGCCAG ACAACACTAT 120

GCCCTCACCA TCTTCCAGTC CATCGAATAT GCTGATGAGC AAAGCCAAAT GCAGTTATCC 180

ACCTTCTTTT CCTTCATGTT GGAAAACTAC ACACATAAGG AAGAGCTAGA ATTAAGAAAT 240

CAATCTCTTG AAAGTGAACA GGACATGAGG GATAGACGGG ATTATGTGGA CTTGATAGAT 300

GTCCCAGACT CCTATAATGG TCCTCGGCTA CAATTTCCTC TCACTTGTAC TGATATTGAT 360

TTACTTCTTG AGGCCTTCAA GGAACAACAG ATACTTCATG CCCATTATGT CTTAGAGGTG 420

CTATTTGAAA CCAAGAAACT CCTGAAGCAA ATGCCGAATT TCACTCACAT ACAAACTTCT 480

CCCTCCAAAG AGGTAACAAT CTGTGGTGAT TTGCATGGGA AACTGGATGA TCTTTTTTTG 540

ATCTTCTACA AGAATGGTCT CCCCTCAGAG AGGAACCCGT ATGTTTTTAA TGGTGACTTT 600

GTAGATCGAG GAAGGAATTC CATAGAGATC CTCATGATCC TGTGTGTGAG TTTTCTTGTC 660

TACCCCAATG ATCTGCACTT GAACAGAGGG AACCATGAAG ATTTTATGAT GAATCTGAGG 720

TATGGCTTCA CGAAAGAAAT TTTGCATAAA TATAAGCTAC ATGGAAAGAG AATCTTACAA 780

ATCTTGGAAG AACTCTATGC CTGGCTCCCA ATCGGTACAA TCATTGACGA TGAAGTCCTG 840

GTCATCCATG GTGGGATATC AGAGACCACA GACTTGAATT TACTCCACCG TGTAGAGAGG 900

AACAAAATGA AATCTGTGCT GATACCACCA ACAGAAACAA GCAGAGACCA TGACACTGAC 960

TCGAAGCACA ATAAAGTAGG TGTGACTTTT AATGCACATG GAAGAATCAA AACAAATGGA 1020

TCTCCTATTG AACACTTAAC AAAGCGTGAA TGGGAACAGA TTATTGATAT TCTGTGGAGT 1080

GATCCTAGAG GCAAAAATGG CTGTTTTCCA AATACGGGCC GAGGAGGGGG CTGCTATTTT 1140

GGACCAGATG TTACTTCCAA GATTCTTAAT AAATACCAGT TGAAGATGCT CATCAGGTCT 1200

CATGAATGTA AGCCCGAAGG GTATGAAATC TGTCATGATG GGAAGGTTGT GACTATATTT 1260

TCTGCTTCTA ATTATTATGA AGAAGGCAGC AATCGAGGAG CTTACATCAA ACTATGTTCT 1320

GGTACAACTC CTCGATTTTT CCAGTATCAA GTAACTAAAG CAACGTGCTT TCAGCCTCTT 1380

CGCCAAAGAG TGCATACTAT GGAAAACAGT GCCATCAAGA TATTAAGAGA GAGAGTGATT 1440

TCACGAAAAA GTGACCTTAC TCGTGCTTTC CAACTTCAAG ACCACAGAAA ATCAGGAAAA 1500

CTTTCTGTGA GCCAGTGGGC TTTTTGCATG GAGAACATTT TGGGGCTGAA CTTACCATGG 1560

AGATCCCTGA GTTCGAATCT GGTAAACATA GACCAAAATG GAAACGTTGA ATACATGTCC 1620

AGCTTCCAGA ATATCCACAT TGAAAAACCT GTACAAGAGG CTCATTCTAC TCTAGTTGAA 1680

ACTCTGTACA GATACCGATC TGACCTGGAA ATCATATTTA ATGCCATTGA CACTGATCAC 1740

TCAGGCCTGA TCTCCATGGA AGAATTTCGT GCCATGTGGA AACTTTTTAG TTCTCACTAC 1800

AGTGTTCTTA TTGATGATTC CCAAGTGAAT AAGCTTGCCA ACATAATGGA CTTGAACAAA 1860

GATGGAAGCA TTGACTTTAA TGAGTTTTTA AAGGCTTTCT ATGTAGTGCA TAGATATGGG 1920

GACTTGATGA AACCTGATGT CAGCAACCTT GGCTAA 1956

Domain Profile

S: 1     idlllevfkkkrilhakyvlevlfeakkvlkqlpnishvstavskevtvvGdlhGklddl  60

         idllle+fk+++ilha+yvlevlfe+kk lkq+pn++h++t++skevt++GdlhGklddl

Q: 119   IDLLLEAFKEQQILHAHYVLEVLFETKKLLKQMPNFTHIQTSPSKEVTICGDLHGKLDDL  178

         8***********************************************************

S: 61    llvlkknGlPsernpyvfnGdfvdrGkrglevllvllslflvfPnavylnrGnhedkvmn  120

         +l+++knGlPsernpyvfnGdfvdrG++++e+l++l+++flv+Pn+++lnrGnhed++mn

Q: 179   FLIFYKNGLPSERNPYVFNGDFVDRGRNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMN  238

         ************************************************************

S: 121   aryGfekevlskykrkgkrilrileevyewlPlgsivdsrvlvvhGGlsestsldllksv  180

         +ryGf+ke+l+kyk +gkril+ilee+y+wlP+g+i+d++vlv+hGG+se+t+l+ll++v

Q: 239   LRYGFTKEILHKYKLHGKRILQILEELYAWLPIGTIIDDEVLVIHGGISETTDLNLLHRV  298

         ************************************************************

S: 181   erkkrksvllpPeessrd................lgrldtdgepreslteteweqiidil  224

         er+k+ksvl+pP+e+srd                +gr++t+g+p e+lt++eweqiidil

Q: 299   ERNKMKSVLIPPTETSRDhdtdskhnkvgvtfnaHGRIKTNGSPIEHLTKREWEQIIDIL  358

         ************************************************************

S: 225   wsdPratnGlvPntlrGaGvyfGPdvtedflkkyelklvirsheckpegyeilhdgkvvt  284

         wsdPr++nG++Pnt rG+G+yfGPdvt+++l+ky+lk++irsheckpegyei+hdgkvvt

Q: 359   WSDPRGKNGCFPNTGRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVT  418

         ************************************************************

S: 285   ifsasnyyeegsnkgayiklnsqltprfvqyivak  319

         ifsasnyyeegsn+gayikl+s++tprf+qy+v+k

Q: 419   IFSASNYYEEGSNRGAYIKLCSGTTPRFFQYQVTK  453

         ********************************996

Domain Sequence
(FASTA)

IDLLLEAFKE QQILHAHYVL EVLFETKKLL KQMPNFTHIQ TSPSKEVTIC GDLHGKLDDL 60

FLIFYKNGLP SERNPYVFNG DFVDRGRNSI EILMILCVSF LVYPNDLHLN RGNHEDFMMN 120

LRYGFTKEIL HKYKLHGKRI LQILEELYAW LPIGTIIDDE VLVIHGGISE TTDLNLLHRV 180

ERNKMKSVLI PPTETSRDHD TDSKHNKVGV TFNAHGRIKT NGSPIEHLTK REWEQIIDIL 240

WSDPRGKNGC FPNTGRGGGC YFGPDVTSKI LNKYQLKMLI RSHECKPEGY EICHDGKVVT 300

IFSASNYYEE GSNRGAYIKL CSGTTPRFFQ YQVTK 335

Keyword

Calcium; Complete proteome; Hydrolase; Iron; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005509	; F:calcium ion binding
GO:0005506	; F:iron ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0050906	; P:detection of stimulus involved in sensory perception

KEGG

InterPros

IPR011992	; EF-hand-like_dom.
IPR018247	; EF_Hand_1_Ca_BS.
IPR018249	; EF_HAND_2.
IPR002048	; EF_hand_Ca-bd.
IPR000048	; IQ_motif_EF-hand-BS.
IPR004843	; Metallo_PEstase_dom.
IPR013235	; PPP_dom.
IPR012008	; Ser/Thr-Pase_EF-hand_contain.
IPR006186	; Ser/Thr-sp_prot-phosphatase.

Pfam

PF00612	; IQ; 1.
PF00149	; Metallophos; 1.
PF08321	; PPP5; 1.

SMARTs

SM00054	; EFh; 3.
SM00015	; IQ; 1.
SM00156	; PP2Ac; 1.

Prosites

PS00018	; EF_HAND_1; 2.
PS50222	; EF_HAND_2; 3.
PS50096	; IQ; 1.
PS00125	; SER_THR_PHOSPHATASE; 1.

Prints

PR00114

; STPHPHTASE.

Created Date

20-Feb-2013