EKS-NOL-00390

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00390

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/Aur	466.8	1.3E-140	43	293	251

Status

Unreviewed

Ensembl Protein

ENSNLEP00000013236

UniProt Accession

G1RJ29;

Protein Name

Protein Synonyms/Alias

Gene Name

AURKC

Gene Synonyms/Alias

AURKC;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000010890	ENSNLEP00000013236	ENSNLET00000013889

Organism

Nomascus leucogenys

Functional Description

Protein Length

309

Protein Sequence
(FASTA)

MSSPRAVVQL GKAQPAGEAS ATASQTAQQP SSPAMRRLTI DDFEIGRPLG KGKFGNVYLA 60

RLKESHFIVA LKVLFKSQIE KEGLEHQLRR EIEIQAHLQH PNILRLYNYF HDARRVYLIL 120

EYAPRGELYK ELQKSEKLDE QRTATIIEEL ADALTYCHDK KVIHRDIKPE NLLLGFRGEV 180

KIADFGWSVH TPSLRRKTMC GTLDYLPPEM IEGRTYDEKV DLWCIGVLCY ELLVGYPPFE 240

STSHSETYRR ILKVDVRFPL SMPLGARDLI SKLLRYQPLE RLPLAQILKH PWVQAHSRRV 300

LPPCAQMAS 309

Nucleotide Sequence
(FASTA)

ATGAGCTCCC CCAGAGCTGT GGTGCAGCTG GGCAAAGCTC AGCCTGCAGG CGAAGCGTCG 60

GCTACAGCAA GCCAAACAGC CCAGCAGCCC AGCAGCCCAG CCATGCGGCG CCTCACAATC 120

GATGACTTTG AAATCGGGCG TCCCCTGGGC AAGGGGAAAT TTGGGAATGT GTACCTGGCT 180

CGGCTTAAGG AAAGCCATTT CATTGTGGCC CTGAAGGTTC TCTTTAAGTC GCAGATAGAG 240

AAGGAAGGAC TGGAGCACCA GCTGCGCCGG GAAATTGAGA TCCAGGCGCA TCTACAACAC 300

CCCAATATCC TGCGCCTGTA TAACTATTTC CATGATGCAC GCCGGGTATA CCTGATTCTG 360

GAATATGCTC CAAGGGGTGA GCTCTACAAG GAGCTGCAAA AAAGCGAGAA ATTAGATGAA 420

CAGCGCACAG CCACGATAAT AGAGGAGTTG GCAGATGCCC TGACCTACTG CCATGACAAG 480

AAAGTGATTC ACAGAGATAT TAAGCCAGAG AACCTGCTGC TGGGGTTCAG GGGTGAGGTG 540

AAGATTGCAG ATTTTGGCTG GTCTGTGCAC ACCCCCTCCC TGAGGAGGAA GACAATGTGT 600

GGGACACTGG ACTACTTGCC CCCAGAAATG ATTGAGGGGA GAACATATGA TGAAAAGGTG 660

GATTTGTGGT GCATTGGAGT GCTCTGCTAT GAGCTGCTGG TGGGATATCC ACCCTTTGAG 720

AGCACTTCCC ACAGTGAGAC TTACAGACGC ATCCTCAAGG TAGATGTGAG GTTTCCGCTA 780

TCAATGCCTC TGGGGGCCCG GGACTTGATT TCCAAGCTTC TCAGATACCA GCCCTTGGAG 840

CGACTACCCC TGGCCCAGAT CCTGAAGCAC CCCTGGGTTC AGGCCCACTC CCGAAGGGTG 900

CTGCCTCCCT GTGCTCAGAT GGCTTCCTGA 930

Domain Profile

S: 1     feiGrklGkGkfGnvylarekkskfivalkvlfkeqlekegvekqlrreieiqshlkhpn  60

         feiGr+lGkGkfGnvylar k+s+fivalkvlfk+q+ekeg+e+qlrreieiq+hl+hpn

Q: 43    FEIGRPLGKGKFGNVYLARLKESHFIVALKVLFKSQIEKEGLEHQLRREIEIQAHLQHPN  102

         9***********************************************************

S: 61    ilrlygyfhdekrvylileyaprGelykelqkskkldeqraakyieeladalsylhkkkv  120

         ilrly+yfhd++rvylileyaprGelykelqks+kldeqr+a++ieeladal+y+h+kkv

Q: 103   ILRLYNYFHDARRVYLILEYAPRGELYKELQKSEKLDEQRTATIIEELADALTYCHDKKV  162

         ************************************************************

S: 121   ihrdikpenlllgskgelkladfGwsvhapsskrktlcGtldylppemvegreydekvdl  180

         ihrdikpenlllg++ge+k+adfGwsvh+ps +rkt+cGtldylppem+egr+ydekvdl

Q: 163   IHRDIKPENLLLGFRGEVKIADFGWSVHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDL  222

         ************************************************************

S: 181   walGvlcyellvGkppfeseskdetykrikkvdlklpssvskgakdliskllkkepkerl  240

         w++GvlcyellvG+ppfes+s++ety+ri kvd+++p s++ ga+dliskll+++p erl

Q: 223   WCIGVLCYELLVGYPPFESTSHSETYRRILKVDVRFPLSMPLGARDLISKLLRYQPLERL  282

         ************************************************************

S: 241   tladvlahpwi  251

         +la++l+hpw+

Q: 283   PLAQILKHPWV  293

         **********8

Domain Sequence
(FASTA)

FEIGRPLGKG KFGNVYLARL KESHFIVALK VLFKSQIEKE GLEHQLRREI EIQAHLQHPN 60

ILRLYNYFHD ARRVYLILEY APRGELYKEL QKSEKLDEQR TATIIEELAD ALTYCHDKKV 120

IHRDIKPENL LLGFRGEVKI ADFGWSVHTP SLRRKTMCGT LDYLPPEMIE GRTYDEKVDL 180

WCIGVLCYEL LVGYPPFEST SHSETYRRIL KVDVRFPLSM PLGARDLISK LLRYQPLERL 240

PLAQILKHPW V 251

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0000793	; C:condensed chromosome
GO:0030496	; C:midbody
GO:0051233	; C:spindle midzone
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013