EKS-NOL-00160

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00160

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/TTK	488.5	5.0E-147	520	786	267

Status

Unreviewed

Ensembl Protein

ENSNLEP00000015095

UniProt Accession

G1RPD1;

Protein Name

Protein Synonyms/Alias

Gene Name

TTK

Gene Synonyms/Alias

TTK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000012403	ENSNLEP00000015095	ENSNLET00000015850

Organism

Nomascus leucogenys

Functional Description

Protein Length

852

Protein Sequence
(FASTA)

MESEDLSGRE LTIDSIMNKV RDIKNKFKNE DLTDELSLNK ISADTTDNSG TVNQIMMMAN 60

SPEDWLSLLL KLERNSVPLS DALLNKLIGR YSQAIEALPP DKYGQNESFA RIQVRFAELK 120

AIQDPDDARD YFQMTRANCK KFAFVHISFA QFELSQGNVK KSKQLLQKAV ERGAVPLEML 180

EIALRNLNLQ KKQLLSEEEK KNLSASTVLT AQESFSSSLG HLQNRNNSCD SRGQTTKARF 240

LYGENMPPQD AEIGYRNSLK QTNKTKQSCP FGRVPVNRLD SPDCDVKTDD SVVPCFIKRQ 300

TSRSECRDLV VPGSKPSGND SCELRNLKSV QNSHFKEPPV SDEKSSDSIT LKNKTESSLL 360

AKLEETKEYQ EPEVPESNQK QWQSKRKSEC INQNPAASSN QWQIPELARK VNTEQKHITF 420

EQPVFSVSKQ SPPISASKWL DPKSICKTPS SNTLDDYMSC FRTPVVKNDF PPACQLSTPY 480

GQPACFQQRQ QQILATPLQN LQVLASSSAN ECISVKGRIY SILKQIGSGG SSKVFQVLNE 540

KKQIYAIKYV NLEEADNQTL DSYRNEIAYL NKLQQHSDKI IRLYDYEITD QYIYMVMECG 600

NIILNSWLKK KKSIDPWERK SYWKNMLEAV HTIHQHGIVH SDLKPANFLI VDGMLKLIDF 660

GIANQMQPDT TSIVKDSQVG TVNYMPPEAI KDMSSSRENG KSKSKISPKS DVWSLGCILY 720

YMTYGKTPFQ QIINQISKLH AIIDPNHEIE FPDIPEKDLQ DVLKCCLKRD PKQRISIPEL 780

LAHPYVQIQT HTGNQMAKGT TEEMKYVLGQ LVGLNSPNSI LKAAKTLYEH YSGGESHNSS 840

SSKTFEKKRG KK 852

Nucleotide Sequence
(FASTA)

ATGGAGTCCG AGGATTTAAG TGGCAGAGAA TTGACAATTG ATTCCATAAT GAACAAAGTG 60

AGAGACATTA AAAATAAGTT TAAAAATGAA GACCTTACTG ATGAACTAAG CTTGAATAAA 120

ATTTCTGCTG ATACTACAGA TAACTCGGGA ACTGTTAACC AAATTATGAT GATGGCAAAC 180

AGCCCAGAGG ACTGGTTGAG TTTGTTGCTC AAACTAGAGA GAAACAGTGT TCCGCTAAGT 240

GATGCTCTTT TAAATAAGTT GATTGGTCGT TACAGTCAAG CAATTGAAGC CCTTCCCCCA 300

GATAAATATG GCCAAAATGA GAGTTTTGCT AGAATTCAAG TGAGATTTGC TGAATTAAAA 360

GCTATTCAAG ACCCAGATGA TGCACGTGAC TACTTTCAAA TGACCAGAGC AAACTGCAAG 420

AAATTTGCCT TTGTTCATAT ATCTTTTGCA CAATTTGAAC TTTCACAAGG TAATGTCAAA 480

AAAAGTAAAC AACTTCTTCA AAAAGCTGTA GAACGTGGAG CAGTACCACT AGAAATGCTG 540

GAAATTGCCC TACGGAATTT GAACCTTCAA AAAAAGCAGC TGCTTTCAGA GGAGGAAAAG 600

AAGAATTTAT CAGCATCTAC GGTATTAACT GCCCAAGAAT CATTTTCCAG TTCACTTGGG 660

CATTTACAGA ATAGGAACAA CAGTTGCGAT TCCAGAGGAC AGACTACTAA AGCCAGGTTT 720

TTATATGGAG AGAACATGCC ACCACAAGAT GCAGAAATAG GTTATCGGAA TTCATTGAAA 780

CAAACTAACA AAACTAAGCA GTCATGCCCG TTTGGAAGAG TCCCAGTTAA CCGTCTAGAT 840

AGCCCAGATT GTGATGTGAA GACAGATGAT TCAGTTGTAC CTTGTTTTAT AAAAAGACAA 900

ACCTCTAGAT CAGAATGCCG AGATTTGGTT GTGCCCGGAT CTAAACCAAG TGGAAATGAT 960

TCCTGTGAAT TGAGAAATTT AAAGTCTGTT CAAAATAGTC ATTTCAAGGA ACCTCCGGTG 1020

TCAGATGAAA AGAGTTCTGA TTCAATAACC CTGAAGAATA AAACTGAATC AAGTCTTCTA 1080

GCTAAATTAG AAGAAACTAA AGAGTATCAA GAACCAGAGG TTCCAGAGAG TAACCAGAAG 1140

CAGTGGCAAT CTAAGAGAAA GTCAGAGTGT ATTAACCAGA ATCCTGCTGC ATCTTCAAAT 1200

CAGTGGCAGA TTCCAGAATT AGCCCGAAAG GTTAATACAG AGCAGAAACA TATCACTTTT 1260

GAGCAACCTG TCTTTTCAGT TTCAAAACAG TCACCGCCAA TATCAGCATC TAAATGGCTT 1320

GACCCAAAAT CTATTTGTAA GACACCAAGC AGCAATACCT TGGATGATTA CATGAGCTGT 1380

TTTAGAACTC CAGTTGTAAA GAATGACTTT CCACCTGCTT GTCAGTTGTC AACACCTTAT 1440

GGTCAACCTG CCTGTTTCCA GCAGCGACAG CAGCAAATAC TTGCTACTCC ACTTCAAAAT 1500

TTACAGGTTT TAGCGTCCTC TTCAGCAAAT GAATGCATTT CGGTTAAAGG AAGAATTTAT 1560

TCCATATTAA AGCAGATAGG AAGTGGAGGT TCAAGCAAGG TATTTCAGGT GTTGAATGAA 1620

AAGAAACAGA TATATGCTAT AAAATATGTG AACTTAGAAG AAGCAGATAA CCAAACTCTT 1680

GATAGTTACC GGAACGAAAT AGCTTATTTG AATAAACTAC AACAACACAG TGATAAGATC 1740

ATCCGACTTT ATGATTATGA AATCACGGAC CAGTATATCT ACATGGTAAT GGAGTGTGGA 1800

AATATTATTC TTAATAGTTG GCTTAAAAAG AAAAAATCCA TTGATCCATG GGAACGCAAG 1860

AGTTACTGGA AAAATATGTT AGAGGCAGTT CACACAATCC ATCAACATGG CATTGTTCAC 1920

AGTGATCTTA AACCAGCTAA CTTTCTGATA GTTGATGGAA TGCTAAAGCT AATTGATTTT 1980

GGGATCGCAA ACCAAATGCA ACCAGATACA ACAAGTATTG TTAAAGATTC TCAGGTTGGC 2040

ACAGTTAATT ATATGCCACC AGAAGCAATC AAAGATATGT CTTCCTCCAG AGAGAATGGG 2100

AAATCTAAGT CAAAGATAAG CCCCAAAAGT GATGTTTGGT CCTTAGGATG TATTTTGTAC 2160

TATATGACTT ATGGGAAAAC ACCGTTTCAG CAGATAATTA ATCAGATTTC TAAATTGCAT 2220

GCCATAATTG ATCCTAATCA TGAAATTGAA TTTCCTGATA TTCCAGAGAA AGATCTTCAA 2280

GATGTGTTAA AGTGTTGTTT AAAAAGGGAC CCAAAACAGA GGATATCCAT TCCTGAGCTC 2340

CTGGCTCATC CATATGTTCA AATTCAAACT CATACAGGTA ACCAAATGGC CAAGGGAACC 2400

ACTGAAGAAA TGAAATATGT TCTGGGCCAA CTTGTTGGTC TGAATTCTCC TAATTCCATT 2460

TTGAAAGCTG CTAAAACTTT ATATGAACAC TATAGTGGTG GTGAAAGTCA TAATTCTTCA 2520

TCATCCAAGA CTTTTGAAAA AAAAAGGGGA AAAAAATGA 2559

Domain Profile

S: 1     yeilkklGsGGsskvfkvksekkrvyalkvvdleaaddqtidgykneielleklqdqs.k  59

         y+ilk++GsGGsskvf+v++ekk++ya+k+v+le+ad+qt+d+y+nei++l+klq++s k

Q: 520   YSILKQIGSGGSSKVFQVLNEKKQIYAIKYVNLEEADNQTLDSYRNEIAYLNKLQQHSdK  579

         99********************************************************9*

S: 60    virlydyeledsllylvmecGdidlnkilkkkksiepdyelvsyykemleavkvihqhGi  119

         +irlydye++d+++y+vmecG+i ln++lkkkksi+p +e++sy+k+mleav++ihqhGi

Q: 580   IIRLYDYEITDQYIYMVMECGNIILNSWLKKKKSIDP-WERKSYWKNMLEAVHTIHQHGI  638

         *************************************.**********************

S: 120   vhsdlkPanfllvdGilklidfGianavaedttsivkesqvGtvnylaPealkdmsssqs  179

         vhsdlkPanfl+vdG+lklidfGian++++dttsivk+sqvGtvny++Pea+kdmsss

Q: 639   VHSDLKPANFLIVDGMLKLIDFGIANQMQPDTTSIVKDSQVGTVNYMPPEAIKDMSSS--  696

         **********************************************************..

S: 180   sereaekskikvsrksdvwslGcilylllygktPfgsirnqvskllaiinPdveiefPei  239

           re++ksk+k+s+ksdvwslGcily+++ygktPf++i+nq+skl+aii+P++eiefP+i

Q: 697   --RENGKSKSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDI  754

         ..**********************************************************

S: 240   tsniekslvellkaclkrnPkkrisvdellsspfv  274

         +   ek+l+++lk+clkr+Pk+ris++ell++p+v

Q: 755   P---EKDLQDVLKCCLKRDPKQRISIPELLAHPYV  786

         *...*****************************96

Domain Sequence
(FASTA)

YSILKQIGSG GSSKVFQVLN EKKQIYAIKY VNLEEADNQT LDSYRNEIAY LNKLQQHSDK 60

IIRLYDYEIT DQYIYMVMEC GNIILNSWLK KKKSIDPWER KSYWKNMLEA VHTIHQHGIV 120

HSDLKPANFL IVDGMLKLID FGIANQMQPD TTSIVKDSQV GTVNYMPPEA IKDMSSSREN 180

GKSKSKISPK SDVWSLGCIL YYMTYGKTPF QQIINQISKL HAIIDPNHEI EFPDIPEKDL 240

QDVLKCCLKR DPKQRISIPE LLAHPYV 267

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013