EKS-NOL-00457

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00457

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/TIF1	N/A	N/A	N/A	N/A	N/A

Status

Unreviewed

Ensembl Protein

ENSNLEP00000016764

UniProt Accession

G1RU39;

Protein Name

Protein Synonyms/Alias

Gene Name

TRIM24

Gene Synonyms/Alias

TRIM24;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000013750	ENSNLEP00000016764	ENSNLET00000017616

Organism

Nomascus leucogenys

Functional Description

Protein Length

1050

Protein Sequence
(FASTA)

MEVAVEKAAA AAAAASAAAS GGPSAAPSGE NEAESRQGPD SERGGEAARL NLLDTCAVCH 60

QNIQSRAPKL LPCLHSFCQR CLPAPQRYLM LPAPMLGSAE TPPPVPAPGS PVSGSSPFAT 120

QVGVIRCPVC SQECAERHII DNFFVKDTTE VPSSTVEKSN QVCTSCEDNA EANGFCVECV 180

EWLCKTCIRA HQRVKFTKDH TVRQKEEVSP EAVGVTSQRP VFCPFHKKEQ LKLYCETCDK 240

LTCRDCQLLE HKEHRYQFIE EAFQNQKVII DTLITKLMEK TKYIKFTGNQ IQNRIIEVNQ 300

NQKQVEQDIK VAIFTLMVEI NKKGKALLHQ LESLAKDHRM KLMQQQQEVA GLSKQLEHVM 360

HFSKWAVSSG SSTALLYSKR LITYRLRHLL RARCDASPVT NNTIQFHCDP SFWAQNIINL 420

GSLVIEDKES QPQMPKQNPV VEQNSQPPSG LSSNQLSKFP TQISLAQLRL QHMQQQVMAQ 480

RQQVQRRPAP VGLPNPRMQG PIQQPSISHQ QPPPRLINFQ NHSPKPNGPV LPPHPQQLRY 540

PPNQNIPRQA IKPNPLQMAF LAQQAIKQWQ ISSGQGTPST TNSTSSTPSS PTITSAAGYD 600

GKAFGSPMID LSSPVGGSYN LPSLPDIDCS STIMLDNIVR KDTNIDHGQP RPPSNRTVQS 660

PNSSVPSPGL AGPVTMTSVH PPIRSPSASS VGSRGSSGSS SKPAGADSTH KVPVVMLEPI 720

RIKQENSGPP ENYDFPVVIV KQESDEESRP QNANYPRSIL TSLLLNSSQS STSEETVLRS 780

DAPDSTGDQP GLHQENSSNG KSEWLDPSQK SPLHVGETRK EDDPNEDWCA VCQNGGELLC 840

CEKCPKVFHL SCHVPTLTNF PSGEWICTFC RDLSKPEVEY DCDAPSHNSE KKKTEGLVKL 900

TPIDKRKCER LLLFLYCHEM SLAFQDPVPL TVPDYYKIIK NPMDLSTIKK RLQEDYSMYS 960

KPEDFVADFR LIFQNCAEFN EPDSEVANAG IKLENYFEEL LKNLYPEKRF PKPEFRNESE 1020

DNKFSDDSDD DFVQPRKKRL KSIEERQLLK 1050

Nucleotide Sequence
(FASTA)

ATGGAGGTGG CGGTGGAGAA GGCGGCGGCG GCGGCGGCAG CGGCCTCAGC GGCGGCCTCC 60

GGGGGGCCCT CGGCGGCGCC GAGCGGGGAG AACGAGGCCG AGAGTCGGCA GGGCCCGGAC 120

TCGGAGCGCG GCGGCGAGGC GGCCCGGCTC AACCTGTTGG ACACTTGCGC CGTGTGCCAC 180

CAGAACATCC AGAGCCGGGC GCCCAAGCTG CTGCCCTGCC TGCACTCTTT CTGCCAGCGC 240

TGCCTGCCCG CGCCCCAGCG CTACCTCATG CTGCCCGCGC CCATGCTGGG CTCGGCTGAG 300

ACCCCTCCGC CCGTCCCTGC CCCCGGCTCG CCGGTCAGCG GCTCGTCGCC GTTCGCCACC 360

CAAGTTGGAG TCATTCGATG CCCAGTTTGC AGCCAAGAAT GTGCAGAGAG ACACATCATA 420

GATAACTTTT TTGTGAAGGA CACTACTGAG GTTCCCAGCA GTACAGTAGA AAAGTCAAAT 480

CAGGTGTGTA CAAGCTGTGA GGACAACGCA GAAGCTAATG GGTTTTGTGT AGAGTGTGTT 540

GAATGGCTCT GCAAGACATG TATCAGAGCT CATCAGAGGG TAAAGTTCAC AAAAGACCAC 600

ACTGTCAGAC AGAAAGAGGA AGTATCTCCA GAGGCAGTTG GTGTCACCAG CCAGCGACCA 660

GTGTTTTGTC CTTTTCATAA AAAGGAGCAG CTGAAACTGT ACTGTGAGAC ATGTGACAAA 720

CTGACATGTC GAGACTGTCA GTTATTAGAA CATAAAGAGC ATAGATACCA GTTTATAGAA 780

GAAGCTTTTC AGAATCAGAA AGTGATCATA GATACACTAA TCACCAAGCT GATGGAAAAA 840

ACAAAATACA TAAAATTCAC AGGAAATCAG ATCCAAAACA GAATTATTGA AGTAAATCAA 900

AATCAAAAGC AGGTGGAACA GGATATTAAA GTTGCTATAT TTACATTGAT GGTAGAAATA 960

AATAAAAAAG GAAAAGCTCT ACTGCATCAG TTAGAGAGCC TTGCAAAGGA CCATCGCATG 1020

AAACTTATGC AGCAACAACA GGAAGTGGCT GGACTCTCTA AACAATTGGA GCATGTCATG 1080

CATTTTTCTA AATGGGCAGT TTCCAGTGGC AGCAGTACAG CATTACTTTA TAGCAAACGA 1140

CTGATTACAT ACCGGTTACG GCACCTCCTT CGTGCAAGGT GTGATGCGTC CCCAGTGACC 1200

AACAACACCA TCCAATTTCA CTGTGATCCT AGTTTCTGGG CTCAAAATAT TATCAACTTA 1260

GGTTCTTTAG TAATCGAGGA TAAAGAGAGC CAGCCACAAA TGCCTAAGCA GAATCCTGTC 1320

GTGGAACAGA ATTCACAGCC ACCAAGTGGT TTATCATCAA ACCAGTTATC CAAGTTCCCA 1380

ACACAGATCA GCCTAGCTCA ATTACGGCTC CAGCATATGC AGCAACAGGT AATGGCTCAG 1440

AGGCAACAGG TGCAACGGAG GCCAGCACCT GTGGGTTTAC CAAACCCTAG AATGCAGGGG 1500

CCCATCCAGC AACCTTCCAT CTCTCATCAG CAGCCCCCTC CACGTTTGAT AAACTTTCAG 1560

AATCACAGCC CCAAACCCAA TGGACCAGTT CTTCCTCCTC ATCCTCAACA ACTGAGATAT 1620

CCACCAAACC AGAATATACC ACGACAAGCA ATAAAGCCCA ACCCCTTACA GATGGCTTTC 1680

TTGGCTCAAC AAGCCATAAA ACAGTGGCAG ATCAGCAGTG GACAGGGAAC CCCATCAACT 1740

ACCAACAGCA CATCCTCTAC TCCTTCCAGC CCCACGATTA CTAGTGCAGC AGGATATGAT 1800

GGAAAGGCTT TTGGTTCACC TATGATCGAT CTGAGCTCAC CAGTGGGAGG GTCTTATAAT 1860

CTTCCCTCTC TTCCGGATAT TGACTGTTCA AGTACTATTA TGCTGGACAA TATTGTGAGG 1920

AAAGATACTA ATATAGATCA TGGCCAGCCA AGACCACCCT CAAACAGAAC GGTCCAGTCA 1980

CCAAATTCAT CAGTGCCATC TCCAGGCCTT GCAGGACCTG TTACTATGAC TAGTGTACAC 2040

CCCCCAATAC GTTCACCTAG TGCCTCCAGC GTTGGAAGCC GAGGAAGCTC TGGCTCTTCC 2100

AGTAAACCAG CAGGAGCTGA CTCTACACAC AAAGTCCCAG TGGTCATGTT GGAGCCAATT 2160

CGAATAAAAC AAGAAAACAG TGGACCACCA GAAAATTATG ATTTCCCTGT TGTTATAGTG 2220

AAGCAAGAAT CAGATGAAGA ATCTAGGCCT CAAAATGCCA ATTATCCAAG AAGCATACTC 2280

ACCTCCCTGC TCTTAAATAG CAGTCAGAGC TCTACTTCTG AGGAGACTGT GCTAAGATCA 2340

GATGCCCCTG ATAGTACAGG AGATCAGCCT GGACTTCACC AGGAGAATTC CTCAAATGGA 2400

AAGTCTGAAT GGCTGGATCC TTCGCAGAAG TCACCTCTTC ATGTTGGAGA GACAAGGAAA 2460

GAGGATGACC CCAATGAGGA CTGGTGTGCA GTTTGTCAAA ATGGAGGGGA ACTCCTCTGC 2520

TGTGAAAAGT GCCCCAAAGT ATTCCATCTT TCTTGTCATG TGCCCACATT GACAAATTTT 2580

CCAAGTGGAG AGTGGATTTG CACTTTCTGC CGAGACTTAT CCAAACCAGA AGTTGAATAT 2640

GATTGTGATG CTCCCAGTCA CAACTCAGAA AAAAAGAAAA CTGAAGGCCT TGTTAAATTA 2700

ACACCTATAG ATAAAAGGAA GTGTGAGCGC CTACTTTTAT TTCTTTACTG CCATGAAATG 2760

AGCCTGGCTT TTCAAGACCC TGTTCCTCTA ACTGTGCCTG ATTATTACAA AATAATTAAA 2820

AATCCAATGG ATTTGTCAAC CATCAAGAAA AGACTACAAG AAGATTATTC CATGTACTCA 2880

AAACCTGAAG ATTTTGTAGC TGATTTTAGA TTGATCTTTC AAAACTGTGC TGAATTCAAT 2940

GAGCCTGATT CAGAAGTAGC CAATGCTGGT ATAAAACTTG AAAATTATTT TGAAGAACTT 3000

CTAAAGAACC TCTATCCAGA AAAAAGGTTT CCCAAACCAG AATTCAGGAA TGAATCAGAA 3060

GATAATAAAT TTAGTGATGA TTCAGATGAT GACTTTGTAC AGCCCCGGAA GAAACGCCTC 3120

AAAAGCATTG AAGAACGCCA GTTGCTTAAA TAA 3153

Domain Profile

N/A

Domain Sequence
(FASTA)

N/A

Keyword

Bromodomain; Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0034056	; F:estrogen response element binding
GO:0008270	; F:zinc ion binding
GO:0071391	; P:cellular response to estrogen stimulus
GO:0016567	; P:protein ubiquitination

KEGG

InterPros

IPR003649	; Bbox_C.
IPR001487	; Bromodomain.
IPR018359	; Bromodomain_CS.
IPR019786	; Zinc_finger_PHD-type_CS.
IPR000315	; Znf_B-box.
IPR011011	; Znf_FYVE_PHD.
IPR001965	; Znf_PHD.
IPR019787	; Znf_PHD-finger.
IPR001841	; Znf_RING.
IPR013083	; Znf_RING/FYVE/PHD.
IPR017907	; Znf_RING_CS.

Pfam

PF00439	; Bromodomain; 1.
PF00628	; PHD; 1.
PF00643	; zf-B_box; 2.

SMARTs

SM00502	; BBC; 1.
SM00336	; BBOX; 2.
SM00297	; BROMO; 1.
SM00249	; PHD; 1.
SM00184	; RING; 1.

Prosites

PS00633	; BROMODOMAIN_1; 1.
PS50014	; BROMODOMAIN_2; 1.
PS50119	; ZF_BBOX; 2.
PS01359	; ZF_PHD_1; 1.
PS50016	; ZF_PHD_2; 1.
PS00518	; ZF_RING_1; 1.
PS50089	; ZF_RING_2; 1.

Prints

PR00503

; BROMODOMAIN.

Created Date

20-Feb-2013