EKS-NOL-00441

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00441

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/RSKL	312.4	4.8E-93	845	1055	211

Status

Unreviewed

Ensembl Protein

ENSNLEP00000017626

UniProt Accession

G1RWJ9;

Protein Name

Protein Synonyms/Alias

Gene Name

RPS6KC1

Gene Synonyms/Alias

RPS6KC1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000014441	ENSNLEP00000017626	ENSNLET00000018505

Organism

Nomascus leucogenys

Functional Description

Protein Length

1065

Protein Sequence
(FASTA)

MTSYRERSAD LARFYTVTEP QRHPRGYTVY KVTARVVSRR NPEDVQEIIV WKRYSDFKKL 60

HKELWQIHKN LFRHSELFPP FAKGIVFGRF DETVIEERRQ CAEDLLQFSA NIPALYNSKQ 120

LEDFFKGGII NDSSELIGPA EAHSDSLIDT FPECSTEGFS SDSDLVSLTV DVDSLAELDD 180

GMASNQNSPI RTFGLHLSSD SSALGAVASD SEQSKTEEER ESRSLFPGSL KPKLGKRDYL 240

EKAGELIKLA LKKEEEDDYE AASDFYRKGV DLLLEGVQGE SSPTRREAVK RRTAEYLMRA 300

ESISSLHGKP QLDDVSQPPG SLSSRPPWNL RSPAEELKAF RVLGVIDKVL LVMDTRTEQT 360

FILKGLRKSS EYSRNRKTII PRCVPNMVCL HKYIISEESV FLVLQHAEGG KLWSYISKFL 420

NRSPEESFDI KEVKKSTLAK VHLQQPTSSP QDSSSFESRG SDGGSMLKAL PLKSSLTPSS 480

QDDSNQEDDG QDSSPKWPDS GSSSEEECTT SYLTLCNEYG QEKIEPGSLN EEPFMKTEGN 540

GVDTKAIKSF PTHLAADSDS PSTQLRAHEL KFFPNDDPEA VSSPRTSDSL SRSKNSPMEF 600

FRIDGKDSAS GLLGLDFGEK YSLKSEPLKP FFTLPDGDSA SRSFNTSESK VEFKAQDTIS 660

RGSDDSVPVI SFKDAAFDDV SGTDEGRPDL LVNLPGELEP TKEAAAMGAT KFTQTNIGII 720

ENKLLEAPDV LCLRLSTEQC QAREEKGIEE LSDPSGPKSH SITEKHYAQE DPRMLFVAAV 780

DHSSSGDMSL LPSSDPKFQG LGVVESAVTA NNTEESLFHI CSPLSGANEY IASTDTLKTE 840

EVLLFTDQTD DLAKEKPASL FQRDSETKGE SGLALEGDKE IHQIFEDLDK KLALTSRFYI 900

PEGCIQRWAA EMVVALDALH REGIVCRDLN PNNILLNDRG HIQLTYFSRW SEVEDSCDSD 960

AIERMYCAPE VGAITEETEA CDWWSLGAVL FELLTGKTLV ECHPAGINTH TTLNMPECVS 1020

EEARSLIQQL LQFNPLERLG AGVAGVEDIK SHPFFTPVDW AELMR 1065

Nucleotide Sequence
(FASTA)

ATGACCTCTT ACCGGGAGCG GAGTGCCGAC CTGGCCCGTT TCTACACTGT CACCGAGCCC 60

CAGCGACACC CAAGGGGCTA CACAGTATAT AAGGTCACCG CCCGGGTTGT TTCACGAAGA 120

AATCCAGAGG ATGTCCAGGA GATAATTGTA TGGAAGAGAT ACAGTGATTT TAAGAAACTA 180

CACAAAGAAC TATGGCAAAT TCACAAAAAC TTATTCCGAC ATTCAGAGTT GTTTCCTCCA 240

TTTGCTAAAG GAATAGTGTT TGGGCGATTT GATGAAACTG TTATCGAAGA GAGAAGACAA 300

TGTGCTGAAG ACCTGCTACA GTTCTCTGCC AATATTCCTG CTCTTTACAA TAGTAAACAG 360

CTTGAAGACT TTTTCAAGGG TGGAATAATT AATGATAGTT CTGAATTAAT TGGTCCTGCT 420

GAAGCTCACT CAGATTCCCT CATTGATACC TTTCCTGAGT GTAGTACGGA AGGCTTCTCG 480

AGTGACAGTG ATCTGGTATC TCTTACTGTT GATGTGGATT CTCTTGCTGA GTTAGATGAT 540

GGAATGGCTT CCAATCAAAA TTCTCCCATT AGAACTTTTG GTCTCCATCT TTCTTCGGAT 600

TCTTCAGCAC TAGGGGCTGT TGCTTCTGAC AGTGAACAGA GCAAAACAGA AGAAGAACGG 660

GAAAGTCGTA GCCTCTTTCC TGGCAGTTTA AAACCCAAGC TTGGCAAGAG AGATTATTTG 720

GAGAAAGCAG GAGAATTAAT AAAGCTGGCT TTAAAAAAGG AAGAAGAAGA CGACTATGAA 780

GCTGCTTCTG ATTTTTATAG GAAAGGAGTT GATTTACTCC TAGAAGGTGT TCAAGGAGAG 840

TCAAGCCCTA CCCGTCGAGA AGCTGTGAAG AGAAGAACAG CTGAGTATCT CATGCGGGCA 900

GAAAGTATCT CTAGTCTTCA TGGGAAACCT CAGCTTGATG ATGTATCTCA GCCTCCAGGA 960

TCACTAAGTT CAAGGCCCCC TTGGAACCTA AGGAGCCCTG CCGAGGAGCT GAAGGCCTTC 1020

AGAGTCCTTG GGGTGATTGA CAAGGTTTTA CTTGTAATGG ACACAAGGAC AGAACAGACT 1080

TTCATTTTAA AAGGTCTAAG GAAAAGCAGT GAATACAGCA GGAACAGAAA GACCATCATC 1140

CCCCGCTGTG TGCCCAACAT GGTGTGTCTG CATAAGTACA TCATCTCTGA GGAGTCAGTA 1200

TTTCTTGTGC TGCAGCATGC AGAAGGTGGC AAACTGTGGT CATATATCAG TAAATTTCTA 1260

AACAGAAGTC CTGAAGAAAG CTTTGACATC AAGGAAGTGA AAAAATCTAC ACTTGCAAAA 1320

GTTCACCTGC AACAGCCAAC TTCTAGTCCT CAGGACAGCA GTAGCTTTGA ATCCAGAGGA 1380

AGTGATGGTG GAAGCATGCT TAAAGCTCTG CCTTTGAAGA GTAGTCTTAC TCCAAGTTCT 1440

CAAGATGACA GCAACCAGGA AGATGATGGC CAAGATAGCT CTCCAAAGTG GCCAGATTCT 1500

GGTTCAAGTT CAGAAGAAGA ATGTACTACT AGTTATTTAA CATTATGCAA TGAATATGGG 1560

CAAGAAAAGA TTGAACCAGG GTCTTTGAAT GAGGAGCCCT TCATGAAGAC TGAAGGGAAT 1620

GGTGTTGATA CTAAAGCTAT TAAAAGCTTC CCAACACACC TTGCTGCTGA CAGTGACAGC 1680

CCCAGCACAC AGCTGAGAGC TCATGAGCTG AAGTTCTTCC CCAACGATGA CCCAGAAGCA 1740

GTTAGTTCTC CAAGAACATC AGATTCCCTC AGTAGATCAA AAAATAGCCC CATGGAATTC 1800

TTTAGGATAG ACGGTAAGGA TAGCGCAAGT GGACTCCTGG GACTTGACTT TGGAGAAAAA 1860

TATAGTCTAA AATCAGAACC TTTGAAACCA TTCTTTACTC TTCCAGATGG AGACAGTGCT 1920

TCTAGGAGTT TTAATACTAG TGAAAGCAAG GTAGAGTTTA AAGCTCAGGA CACCATTAGC 1980

AGGGGCTCAG ATGACTCAGT GCCAGTTATT TCATTTAAAG ATGCTGCTTT TGATGATGTC 2040

AGTGGTACTG ATGAAGGAAG ACCTGATCTT CTTGTAAATT TACCTGGTGA ATTGGAGCCA 2100

ACAAAAGAAG CTGCGGCAAT GGGAGCTACT AAGTTTACAC AAACTAATAT AGGGATAATA 2160

GAAAATAAAC TCTTGGAAGC CCCTGACGTT TTATGCCTTA GGCTTAGTAC TGAACAATGC 2220

CAAGCACGTG AGGAGAAAGG CATAGAGGAA CTGAGTGATC CCTCTGGGCC CAAATCCCAT 2280

AGTATAACAG AGAAACACTA TGCACAGGAG GATCCCAGGA TGTTATTTGT AGCAGCTGTT 2340

GATCATAGTA GTTCAGGAGA TATGTCTTTG TTACCCAGCT CAGATCCCAA GTTTCAAGGA 2400

CTTGGAGTGG TTGAGTCAGC AGTAACTGCA AACAACACAG AAGAAAGCTT ATTCCATATT 2460

TGTAGTCCAC TCTCAGGTGC TAATGAATAT ATTGCAAGCA CAGACACTTT AAAAACAGAA 2520

GAAGTATTGC TGTTTACAGA TCAGACTGAT GATTTGGCTA AAGAGAAACC AGCTTCTTTA 2580

TTCCAGAGAG ACTCTGAGAC TAAGGGAGAA AGTGGTTTAG CGCTAGAAGG AGACAAGGAA 2640

ATACATCAGA TTTTTGAGGA CCTTGATAAA AAATTAGCAC TAACCTCCAG GTTTTACATC 2700

CCAGAGGGCT GCATTCAAAG ATGGGCAGCT GAAATGGTGG TAGCCCTTGA TGCTTTACAT 2760

AGAGAGGGAA TTGTGTGCCG CGATTTGAAC CCAAACAACA TCTTATTGAA TGATAGAGGA 2820

CACATTCAGC TAACGTATTT TAGCAGGTGG AGTGAGGTTG AAGATTCCTG TGACAGCGAT 2880

GCCATAGAGA GAATGTACTG TGCCCCAGAG GTTGGAGCAA TCACTGAAGA AACTGAAGCC 2940

TGTGATTGGT GGAGTTTGGG TGCTGTCCTC TTTGAACTTC TCACTGGCAA GACTCTGGTT 3000

GAATGCCATC CAGCAGGAAT AAATACTCAC ACTACTTTGA ACATGCCAGA ATGTGTCTCT 3060

GAAGAGGCTC GCTCACTCAT TCAACAGCTC TTGCAGTTCA ATCCTCTGGA ACGACTTGGT 3120

GCTGGAGTTG CTGGGGTTGA AGATATCAAA TCTCATCCAT TTTTTACCCC TGTGGATTGG 3180

GCAGAACTGA TGAGATGA 3198

Domain Profile

S: 130   rtesllllvgeeptsrsqreaeeesearvklefssdkskaprGnrirregqnsspssske  189

          t+++++l++e+p+s++qr++e+++e+   le++                        ke

Q: 845   FTDQTDDLAKEKPASLFQRDSETKGESGLALEGD------------------------KE  880

         4899999*********************999999........................99

S: 190   iklvsedadkslealsrgldkalqsvdkalslrravwslpEelikqWaaelvvaleaLHe  249

         i++++ed+dk+l+++sr                   +++pE++i++Waae+vval+aLH+

Q: 881   IHQIFEDLDKKLALTSR-------------------FYIPEGCIQRWAAEMVVALDALHR  921

         *****************...................************************

S: 250   egvlirDlnadniLldskGhllltYfgrwsevekscrreavdnlysAPEvgaiselteas  309

         eg+++rDln++niLl+++Gh++ltYf+rwseve+sc+++a++++y+APEvgai+e+tea+

Q: 922   EGIVCRDLNPNNILLNDRGHIQLTYFSRWSEVEDSCDSDAIERMYCAPEVGAITEETEAC  981

         ************************************************************

S: 310   DwWslGalLyelLtGkalaeahPsgiqahtelqlPevvSeeAkdLleeLLqfePalRlGa  369

         DwWslGa+L+elLtGk+l+e+hP+gi++ht+l++Pe+vSeeA++L+++LLqf+P +RlGa

Q: 982   DWWSLGAVLFELLTGKTLVECHPAGINTHTTLNMPECVSEEARSLIQQLLQFNPLERLGA  1041

         ************************************************************

S: 370   GeagvdelkaHPFF  383

         G+agv+++k+HPFF

Q: 1042  GVAGVEDIKSHPFF  1055

         *************9

Domain Sequence
(FASTA)

FTDQTDDLAK EKPASLFQRD SETKGESGLA LEGDKEIHQI FEDLDKKLAL TSRFYIPEGC 60

IQRWAAEMVV ALDALHREGI VCRDLNPNNI LLNDRGHIQL TYFSRWSEVE DSCDSDAIER 120

MYCAPEVGAI TEETEACDWW SLGAVLFELL TGKTLVECHP AGINTHTTLN MPECVSEEAR 180

SLIQQLLQFN PLERLGAGVA GVEDIKSHPF F 211

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005769	; C:early endosome
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004672	; F:protein kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR007330	; MIT.
IPR001683	; Phox.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF04212	; MIT; 1.
PF00069	; Pkinase; 1.
PF00787	; PX; 1.

SMARTs

SM00745	; MIT; 1.
SM00312	; PX; 1.

Prosites

PS50011	; PROTEIN_KINASE_DOM; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013