EKS-NOL-00226

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00226

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	342.0	1.8E-102	16	268	253

Status

Unreviewed

Ensembl Protein

ENSNLEP00000017863

UniProt Accession

G1RX86;

Protein Name

Protein Synonyms/Alias

Gene Name

PRKAA2

Gene Synonyms/Alias

PRKAA2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000014678	ENSNLEP00000017863	ENSNLET00000018755

Organism

Nomascus leucogenys

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MAEKQKHDGR VKIGHYVLGD TLGVGTFGKV KIGEHQLTGH KVAVKILNRQ KIRSLDVVGK 60

IKREIQNLKL FRHPHIIKLY QVISTPTDFF MVMEYVSGGE LFDYICKHGR VEEMEARRLF 120

QQILSAVDYC HRHMVVHRDL KPENVLLDAH MNAKIADFGL SNMMSDGEFL RTSCGSPNYA 180

APEVISGRLY AGPEVDIWSC GVILYALLCG TLPFDDEHVP TLFKKIRGGV FYIPEYLNRS 240

VATLLMHMLQ VDPLKRATIK DIREHEWFKQ DLPSYLFPED PSYDANVIDD EAVKEVCEKF 300

ECTESEVMNS LYSGDPQDQL AVAYHLIIDN RRIMNQASEF YLASSPPSGS FMDDSAMHIP 360

PGLKPHPERM PPLIADSPKA RCPLDALNTT KPKSLAVKKA KWHLGIRSQS KPYDIMAEVY 420

RAMKQLDFEW KVVNAYHLRV RRKNPVTGSY VKMSLQLYLV DNRSYLLDFK SIDDEVVEQR 480

SGSSTPQRSC SAAGLHRPRS SFDSTTAESH SLSGSLTGSL TGSTLSSVSP RLGSHTMDFF 540

EMCASLITTL AR 552

Nucleotide Sequence
(FASTA)

ATGGCTGAGA AGCAGAAGCA CGACGGGCGG GTGAAGATCG GACACTACGT GCTGGGCGAC 60

ACGCTGGGCG TCGGCACCTT TGGCAAAGTG AAGATTGGAG AACATCAATT AACAGGCCAT 120

AAAGTGGCAG TTAAAATCTT AAATAGACAG AAGATTCGCA GTTTAGATGT TGTTGGGAAA 180

ATAAAACGAG AAATTCAAAA TCTAAAACTC TTTCGTCATC CTCATATTAT CAAACTATAC 240

CAGGTGATCA GCACTCCAAC AGATTTTTTT ATGGTAATGG AATATGTGTC TGGAGGTGAA 300

TTATTTGACT ACATCTGTAA GCATGGACGG GTTGAAGAGA TGGAAGCCAG GCGGCTCTTT 360

CAGCAGATTC TGTCTGCTGT GGATTACTGT CATAGGCATA TGGTTGTTCA TCGAGACCTG 420

AAACCAGAAA ATGTCCTGTT GGACGCACAC ATGAATGCCA AGATAGCTGA TTTTGGATTA 480

TCTAATATGA TGTCAGATGG TGAATTTCTG AGAACTAGTT GCGGATCTCC AAATTATGCA 540

GCACCTGAAG TCATCTCAGG CAGATTGTAT GCAGGTCCTG AAGTTGATAT CTGGAGCTGT 600

GGTGTTATCT TGTATGCTCT TCTTTGTGGC ACCCTCCCAT TTGATGATGA GCATGTACCC 660

ACGTTATTTA AGAAGATCCG AGGCGGTGTC TTTTATATCC CAGAATATCT CAATCGTTCT 720

GTCGCCACTC TCCTGATGCA TATGCTGCAG GTTGACCCAC TGAAACGAGC AACTATCAAA 780

GACATAAGAG AGCATGAATG GTTTAAACAA GATTTGCCCA GTTACTTATT TCCTGAAGAC 840

CCTTCCTATG ATGCTAATGT CATTGATGAT GAGGCTGTGA AAGAAGTGTG TGAAAAATTT 900

GAATGTACAG AATCAGAAGT AATGAACAGT TTATATAGTG GTGACCCTCA AGACCAGCTT 960

GCAGTGGCTT ATCATCTTAT CATTGACAAT CGGAGAATAA TGAACCAAGC CAGTGAGTTC 1020

TACCTCGCCT CTAGTCCTCC ATCTGGTTCT TTTATGGATG ATAGTGCCAT GCATATTCCC 1080

CCAGGCCTGA AACCTCATCC AGAAAGGATG CCACCACTTA TAGCAGACAG CCCCAAAGCA 1140

AGATGTCCAT TGGATGCACT GAATACGACT AAGCCCAAAT CTTTAGCTGT GAAAAAAGCC 1200

AAGTGGCATC TTGGAATCCG AAGTCAGAGC AAACCGTATG ACATCATGGC TGAAGTTTAC 1260

CGAGCTATGA AGCAGCTGGA TTTTGAATGG AAGGTAGTGA ATGCATACCA TCTTCGTGTA 1320

AGAAGAAAAA ATCCAGTGAC TGGCAGTTAC GTGAAAATGA GCTTACAACT TTACCTGGTT 1380

GATAACAGGA GCTATCTTTT GGACTTTAAA AGCATTGATG ATGAAGTAGT GGAGCAGAGG 1440

TCTGGTTCCT CAACACCTCA GCGTTCCTGT TCTGCTGCTG GCTTACACAG ACCAAGATCA 1500

AGTTTTGATT CCACAACTGC AGAGAGCCAT TCACTTTCTG GCTCTCTCAC TGGCTCTTTG 1560

ACCGGAAGCA CATTGTCTTC AGTTTCACCT CGCCTGGGCA GTCACACCAT GGATTTTTTT 1620

GAAATGTGTG CCAGTCTGAT TACTACTTTA GCCCGTTGA 1659

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl.seeslekikrEieilkklkhpn  59

         y l++tlG g+fgkVk  +h++t++kvavKi++++k+ s + + kikrEi+ lk ++hp+

Q: 16    YVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNRQKIrSLDVVGKIKREIQNLKLFRHPH  75

         8899********************************96667788****************

S: 60    iikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgi  119

         iikl++vi+t +++++v+ey+sggeLfdyi ++gr++e ear+lf+q++sav+Y+h++ +

Q: 76    IIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMV  135

         ************************************************************

S: 120   vHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkv  179

         vHrDlKpeN+lld+++n kiaDFGl+n++++g+ l+t+cGsp+YaaPe+++g+ Y gp+v

Q: 136   VHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEV  195

         ************************************************************

S: 180   DvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpek  239

         D+Ws+Gv+Lyal++g+lPfd+e++ +l++ki  g + ip++l++++++Ll ++L+vdp k

Q: 196   DIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLK  255

         ************************************************************

S: 240   Ratieeilkhewl  252

         Rati++i++hew+

Q: 256   RATIKDIREHEWF  268

         ************7

Domain Sequence
(FASTA)

YVLGDTLGVG TFGKVKIGEH QLTGHKVAVK ILNRQKIRSL DVVGKIKREI QNLKLFRHPH 60

IIKLYQVIST PTDFFMVMEY VSGGELFDYI CKHGRVEEME ARRLFQQILS AVDYCHRHMV 120

VHRDLKPENV LLDAHMNAKI ADFGLSNMMS DGEFLRTSCG SPNYAAPEVI SGRLYAGPEV 180

DIWSCGVILY ALLCGTLPFD DEHVPTLFKK IRGGVFYIPE YLNRSVATLL MHMLQVDPLK 240

RATIKDIREH EWF 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0004679	; F:AMP-activated protein kinase activity
GO:0005524	; F:ATP binding

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013