EPS-NOL-00017

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00017

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	71.3	7.1E-20	158	310	153

Status

Unreviewed

Ensembl Protein

ENSNLEP00000018451

UniProt Accession

G1RYX4;

Protein Name

Protein Synonyms/Alias

Gene Name

EPM2A

Gene Synonyms/Alias

EPM2A;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000015203	ENSNLEP00000018451	ENSNLET00000019376

Organism

Nomascus leucogenys

Functional Description

Protein Length

331

Protein Sequence
(FASTA)

MRFRFGVVVP PAVAGARPEL LVVGSRPELG CWEPRGAVRL RPAGTAAGAG ALALQEPGLW 60

LGEVELAAEE AAQDGAEPGR VDTFWYKFLK REPGGELSWE GNGPHHDRCC TYNENNLVDG 120

VYCLPVGHWI EATGHTNEMK HTTDFYFNIA GHQAMHYSRI LPNIWLGSCP RQVEHVTIKL 180

KHELGITAVM NFQTEWDIVQ NSSGCNRYPE PMTPDTMIKL YREEGLAYIW MPTPDMSTEG 240

RVQMLPQAVC LLHALLEKGH IVYVHCNAGV GRSTAAVCGW LQYVMGWNLR KVQYFLMAKR 300

PAVYIDEEAL ARAQEDFFQK FGKVRSSVCS L 331

Nucleotide Sequence
(FASTA)

ATGCGCTTCC GCTTCGGGGT GGTGGTGCCG CCAGCCGTGG CCGGCGCCCG GCCGGAGCTG 60

CTGGTGGTGG GGTCGCGCCC CGAGCTGGGG TGTTGGGAGC CGCGCGGTGC CGTACGCCTG 120

AGGCCAGCCG GCACCGCGGC GGGCGCCGGG GCGCTGGCGC TGCAGGAGCC GGGCCTGTGG 180

CTCGGAGAGG TGGAGCTGGC GGCTGAGGAG GCGGCGCAGG ACGGGGCGGA GCCGGGCCGC 240

GTGGACACGT TCTGGTACAA GTTCCTGAAG CGGGAGCCGG GAGGAGAGCT CTCCTGGGAA 300

GGCAATGGAC CTCATCATGA CCGTTGCTGT ACTTACAATG AAAACAACTT GGTGGATGGT 360

GTGTATTGTC TCCCAGTAGG ACACTGGATT GAGGCCACTG GGCACACCAA TGAAATGAAG 420

CACACAACAG ACTTCTATTT TAATATTGCA GGCCACCAAG CCATGCATTA TTCAAGAATT 480

CTACCAAATA TCTGGCTGGG TAGCTGCCCT CGTCAAGTGG AACATGTAAC CATCAAACTG 540

AAGCATGAAT TGGGGATTAC AGCTGTAATG AATTTCCAGA CTGAATGGGA TATTGTACAG 600

AATTCCTCAG GCTGTAACCG CTACCCAGAG CCCATGACTC CAGACACTAT GATTAAACTA 660

TATAGGGAAG AAGGCTTGGC CTACATCTGG ATGCCAACAC CAGATATGAG CACTGAAGGC 720

CGAGTGCAGA TGCTGCCCCA GGCGGTGTGC CTGCTGCATG CGCTGCTGGA GAAGGGACAC 780

ATCGTGTACG TGCACTGCAA CGCTGGGGTG GGCCGCTCCA CCGCAGCTGT CTGCGGCTGG 840

CTCCAGTATG TGATGGGCTG GAACCTGAGG AAGGTGCAGT ATTTCCTCAT GGCCAAGAGG 900

CCGGCTGTCT ACATTGATGA AGAAGCCTTG GCCCGGGCAC AAGAAGATTT TTTCCAGAAA 960

TTTGGGAAGG TTCGTTCTTC TGTGTGTAGC CTGTAG 996

Domain Profile

S: 3     teilpglylgdqataldrreLs...klgitvvinaslsvikvq...........viPe..  46

         ++ilp+++lg+    +++++++   +lgit v+n  ++   vq            +P+

Q: 158   SRILPNIWLGSCPRQVEHVTIKlkhELGITAVMNFQTEWDIVQnssgcnrypepMTPDtm  217

         799********9999999887432367999999976654333311111111222356522

S: 47    ..ylikkgityknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlv  104

           +++++g  y  +p  D  ++  +q++++a+++++   ekg+ v+vHC+aGv+RS++ v

Q: 218   ikLYREEGLAYIWMPTPDMSTEGRVQMLPQAVCLLHALLEKGHIVYVHCNAGVGRSTAAV  277

         22466799****************************************************

S: 105   laYLmkveglslsdAieavkrkrpsiepnegfl  137

         +++L +v+g++l+++   +++krp+++ +e+ l

Q: 278   CGWLQYVMGWNLRKVQYFLMAKRPAVYIDEEAL  310

         ****************************99976

Domain Sequence
(FASTA)

SRILPNIWLG SCPRQVEHVT IKLKHELGIT AVMNFQTEWD IVQNSSGCNR YPEPMTPDTM 60

IKLYREEGLA YIWMPTPDMS TEGRVQMLPQ AVCLLHALLE KGHIVYVHCN AGVGRSTAAV 120

CGWLQYVMGW NLRKVQYFLM AKRPAVYIDE EAL 153

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0005844	; C:polysome
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:2001070	; F:starch binding

KEGG

InterPros

IPR013784	; Carb-bd-like_fold.
IPR002044	; CBM_fam20.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR013783	; Ig-like_fold.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00686	; CBM_20; 1.
PF00782	; DSPc; 1.

SMARTs

SM01065

; CBM_2; 1.

Prosites

PS51166	; CBM20; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

Created Date

20-Feb-2013