EKS-NOL-00188

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-NOL-00188

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	389.6	8.0E-117	4	284	281

Status

Unreviewed

Ensembl Protein

ENSNLEP00000019386

UniProt Accession

G1S1J8;

Protein Name

Protein Synonyms/Alias

Gene Name

MOK

Gene Synonyms/Alias

MOK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000015986	ENSNLEP00000019386	ENSNLET00000020367

Organism

Nomascus leucogenys

Functional Description

Protein Length

419

Protein Sequence
(FASTA)

MKNYKAIGKI GEGTFSEVMK MQSLRDGNYY ACKQMKQRFE SIEQVNNLRE IQALRRLNPH 60

PNILMLHEVV FDRKSGSLAL ICELMDMNIY ELIRGRRYPL SEKKIMHYMY QLCKSLDHIH 120

RNGIFHRDVK PENILIKQDV LKLGDFGSCR SVYSKQPYTE YISTRWYRAP ECLLTDGFYT 180

YKMDLWSAGC VFYEIARLAL LPLQSRCHGH SEPIIYIRGP SWCRLCSHKP SRAMNFDFPF 240

KKGSGIPLLT TNLSPQCLSL LHAMVAYDPD ERIAAHQALQ HPYFQEQRKT EKRALGSHRK 300

AGFPAHPVAP EPLSHSCQVS KEGGKQKQSL KQEEDHPKGQ GPAYVMELPK LKLSGVVKLS 360

SYSSPTLQSV LGSGTNGRVP VLRPLKCVPA SKKTDPRKDL KPAPQQCRLP TIVRKGGRY 419

Nucleotide Sequence
(FASTA)

ATGAAGAACT ATAAAGCAAT TGGCAAAATA GGAGAGGGAA CGTTTTCTGA AGTTATGAAG 60

ATGCAAAGCC TGAGAGATGG AAACTACTAT GCATGTAAAC AAATGAAGCA GCGCTTTGAA 120

AGTATTGAGC AAGTCAACAA CCTACGAGAG ATCCAAGCAC TGAGGCGCCT GAATCCGCAC 180

CCAAACATTC TTATGTTGCA TGAAGTGGTT TTTGACAGAA AATCTGGTTC TCTTGCACTA 240

ATATGTGAAC TTATGGACAT GAATATTTAT GAGCTAATAC GAGGGAGAAG ATACCCATTA 300

TCAGAAAAAA AAATTATGCA CTATATGTAC CAGTTATGTA AGTCCCTGGA TCATATTCAC 360

AGAAATGGAA TATTTCACAG AGATGTAAAA CCAGAAAATA TACTAATAAA GCAGGATGTC 420

CTGAAATTAG GGGACTTTGG CTCCTGCCGG AGTGTCTATT CCAAGCAGCC GTACACAGAA 480

TACATCTCCA CCCGCTGGTA CCGGGCCCCG GAGTGTCTCC TCACCGACGG GTTCTACACG 540

TACAAGATGG ACCTGTGGAG CGCCGGCTGT GTGTTCTACG AGATCGCCAG GCTCGCGCTC 600

CTTCCTTTAC AATCCAGATG TCATGGTCAT TCTGAGCCCA TCATTTACAT CAGGGGTCCC 660

TCTTGGTGTA GACTCTGCAG TCATAAACCG TCGAGAGCTA TGAATTTTGA TTTTCCTTTT 720

AAAAAGGGAT CAGGAATACC TCTACTGACA ACCAATTTGT CCCCACAATG CCTCTCCCTC 780

CTGCACGCAA TGGTGGCCTA TGATCCCGAT GAGAGAATCG CCGCCCACCA GGCCTTGCAG 840

CACCCCTACT TCCAAGAACA GAGGAAAACA GAGAAGCGGG CTCTGGGCAG CCACAGAAAA 900

GCTGGCTTTC CGGCACACCC TGTGGCACCG GAGCCACTCA GTCACAGCTG CCAGGTTTCC 960

AAGGAGGGCG GAAAGCAGAA ACAGTCCCTA AAGCAAGAGG AGGACCATCC CAAGGGACAA 1020

GGACCAGCCT ATGTCATGGA ACTGCCCAAA CTAAAGCTTT CGGGAGTGGT CAAACTGTCG 1080

TCTTACTCCA GCCCCACGCT GCAGTCCGTG CTTGGATCCG GAACAAATGG AAGAGTGCCG 1140

GTGCTGAGAC CCTTGAAGTG CGTCCCTGCG AGCAAGAAGA CAGATCCGCG GAAGGACCTT 1200

AAGCCTGCTC CTCAGCAGTG TCGCCTGCCC ACCATAGTGC GGAAAGGCGG AAGATACTGA 1260

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         yk+i k+G+Gtf+ev++++sl++g+++a+k+mk++fes+e+v+nlre+++l++ln+h+ni

Q: 4     YKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPHPNI  63

         99**********************************************************

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         ++l+ev++dr+++sl+l++elm++n+y+li++rr+ lse+k+++++yq++k+l++ih++g

Q: 64    LMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIHRNG  123

         ************************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         +fhrd+kPenilik ++++kl+dfG++r+v+sk+Pyt+y+strwyraPe+ll++g+y+++

Q: 124   IFHRDVKPENILIK-QDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYK  182

         **************.*********************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +dlw++Gcv++e+a l +l+P  s     +  +  +  P+   +   +k ++a+n++fp+

Q: 183   MDLWSAGCVFYEIARL-ALLPLQSRCHGHSEPIIYIRGPSWCRLCS-HKPSRAMNFDFPF  240

         **************99.79999999998887666667788877776.89***********

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         ++gs+++ l++n+s ++l+ll++++aydPder++a+qal++pyf

Q: 241   KKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YKAIGKIGEG TFSEVMKMQS LRDGNYYACK QMKQRFESIE QVNNLREIQA LRRLNPHPNI 60

LMLHEVVFDR KSGSLALICE LMDMNIYELI RGRRYPLSEK KIMHYMYQLC KSLDHIHRNG 120

IFHRDVKPEN ILIKQDVLKL GDFGSCRSVY SKQPYTEYIS TRWYRAPECL LTDGFYTYKM 180

DLWSAGCVFY EIARLALLPL QSRCHGHSEP IIYIRGPSWC RLCSHKPSRA MNFDFPFKKG 240

SGIPLLTTNL SPQCLSLLHA MVAYDPDERI AAHQALQHPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Dasypus novemcinctus"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013