EPS-NOL-00009

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-NOL-00009

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	163.7	2.4E-48	174	320	147

Status

Unreviewed

Ensembl Protein

ENSNLEP00000020470

UniProt Accession

G1S4N2;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP13

Gene Synonyms/Alias

DUSP13;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSNLEG00000016844	ENSNLEP00000020470	ENSNLET00000021486

Organism

Nomascus leucogenys

Functional Description

Protein Length

327

Protein Sequence
(FASTA)

MGLPQPRLPA PAVQAGPATA GCRPELRGQS WSLLPAMGLC HFATLALVLL VLLEALAQAD 60

TQKMVEAQRG VRPRACYAIW LLLAPAPPLS HCLQSPQKQH QVCGDRRLKA GSTNCPSEKC 120

TAQARYSHRM DLLQKQDLRR PKIHRAVRAS PYQPPTLASL QRLLWVRQAA TLNHIDEVWP 180

SLFLGDAYAA RDKSKLMQLG ITHVVNAAAG KFQVDTGAKF YRGMSLEYYG IEADDNPFFD 240

LSVYFLPVGR YIRAALSVPQ GRVLVHCAMG VSRSATLVLA FLMIYENMTL VEAIQTVQAH 300

RNICPNSGFL RQLQVLDNRL GRETGRF 327

Nucleotide Sequence
(FASTA)

ATGGGTCTTC CCCAACCGAG GCTTCCTGCA CCAGCTGTGC AGGCTGGACC AGCAACTGCG 60

GGGTGCCGGC CAGAGCTGAG GGGCCAGAGC TGGTCCTTAC TCCCTGCCAT GGGCCTCTGC 120

CACTTTGCCA CCCTGGCACT GGTCCTGCTG GTGCTGCTGG AGGCTCTGGC CCAGGCGGAC 180

ACACAGAAGA TGGTGGAAGC CCAGCGTGGG GTCCGCCCTA GAGCCTGCTA CGCCATCTGG 240

CTCCTCCTGG CGCCTGCACC CCCTCTCAGC CACTGTCTTC AGTCTCCACA GAAACAGCAT 300

CAAGTGTGCG GAGACAGGCG GCTGAAAGCC GGCAGCACAA ACTGCCCGTC AGAGAAGTGC 360

ACAGCCCAGG CCAGATACTC CCACAGGATG GACTTACTGC AGAAGCAGGA CCTCCGGAGG 420

CCCAAGATCC ACAGGGCAGT CCGGGCATCT CCCTACCAGC CGCCCACGTT GGCTTCACTG 480

CAGCGCTTGC TATGGGTCCG TCAGGCTGCC ACACTGAACC ATATCGACGA GGTCTGGCCC 540

AGCCTCTTCC TGGGAGATGC GTACGCAGCC CGGGACAAGA GCAAGCTGAT GCAGCTGGGA 600

ATCACCCACG TTGTGAATGC CGCTGCGGGC AAGTTCCAGG TGGACACAGG TGCCAAGTTC 660

TACCGTGGAA TGTCCCTGGA GTACTATGGC ATCGAGGCGG ATGACAACCC CTTCTTCGAC 720

CTCAGTGTCT ACTTTCTGCC TGTTGGTCGA TACATCCGAG CTGCCCTCAG TGTTCCCCAA 780

GGCCGCGTGC TGGTACACTG TGCCATGGGG GTAAGCCGCT CTGCCACACT TGTCCTGGCC 840

TTCCTCATGA TCTACGAGAA CATGACGCTG GTAGAGGCCA TCCAGACGGT GCAGGCCCAC 900

CGCAATATCT GCCCTAACTC AGGCTTCCTC CGGCAGCTCC AGGTTCTGGA CAACCGACTG 960

GGGCGGGAGA CGGGGCGGTT CTGA 984

Domain Profile

S: 1     evteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipv  60

         +++e++p+l+lgd+  a d+ +L +lgit+v+na+++ ++v+++ ++++ ++ +y +i++

Q: 174   HIDEVWPSLFLGDAYAARDKSKLMQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEA  233

         699*********************************************************

S: 61    dDsdvtdllqyfdeaaefidea.kekggkvlvHCaaGvsRSatlvlaYLmkveglslsdA  119

         dD++ +dl+ yf ++ ++i  a + ++g+vlvHCa+GvsRSatlvla+Lm++e+++l++A

Q: 234   DDNPFFDLSVYFLPVGRYIRAAlSVPQGRVLVHCAMGVSRSATLVLAFLMIYENMTLVEA  293

         *********************9999***********************************

S: 120   ieavkrkrpsiepnegfleQLlelekkl  147

         i++v+++r +i+pn+gfl+QL  l+++l

Q: 294   IQTVQAHR-NICPNSGFLRQLQVLDNRL  320

         ********.****************987

Domain Sequence
(FASTA)

HIDEVWPSLF LGDAYAARDK SKLMQLGITH VVNAAAGKFQ VDTGAKFYRG MSLEYYGIEA 60

DDNPFFDLSV YFLPVGRYIR AALSVPQGRV LVHCAMGVSR SATLVLAFLM IYENMTLVEA 120

IQTVQAHRNI CPNSGFLRQL QVLDNRL 147

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR020417	; Atypical_DUSP.
IPR020405	; Atypical_DUSP_famA.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR020422	; Dual-sp_phosphatase_subgr_cat.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

SM00195

; DSPc; 1.

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.
PS50054	; TYR_PHOSPHATASE_DUAL; 1.

Prints

PR01908	; ADSPHPHTASE.
PR01909	; ADSPHPHTASEA.

Created Date

20-Feb-2013