EKS-ORA-00183

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00183

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	480.6	1.4E-144	4	286	283

Status

Unreviewed

Ensembl Protein

ENSOANP00000000406

UniProt Accession

F6YVH1;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000000233	ENSOANP00000000406	ENSOANT00000000406

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

488

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKETGQIV AIKIFYEKPE KSVNKIAMRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RALEFLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTTYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVIKVGNL TPHLQSIFLR SPIFSGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PEDRISSTAL LHHDYFTRDG FIKKFMPELR 300

AKLQQEAKVN SIKKPRENFK DNEPIKEERK AVHVNKIANN LTVGKDTDKG KKTKDGKAKV 360

KIKVGRGEIS EAQKNDHGSV HCHGDVSENF LPLQDLKPAD TELLPSPAIR SGAIITGHLK 420

EEMHLGGCMT MPPINPNSSN LTTTSLNYPH SSTSNRLPDK GKKRRSPWQT GCNIKQEDGT 480

FTQVSSKK 488

Nucleotide Sequence
(FASTA)

ATGGAGATGT ACGAGACCCT TGGAAAAGTG GGAGAGGGAA GCTATGGCAC AGTCATGAAG 60

TGTAAGCATA AGGAAACCGG GCAGATAGTG GCCATAAAGA TATTTTATGA GAAACCAGAA 120

AAATCTGTGA ACAAAATTGC AATGAGAGAA ATAAAGTTCC TAAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATTTGATTGA AGTATTTAGA CAGAAAAAGA AAATTCATTT GGTGTTTGAA 240

TTTATTGATC ACACAGTTTT AGATGAACTA CAGCATTACT GTCATGGATT GGAGAGCAAA 300

CGACTTAGGA AATACCTTTT CCAGATCCTT CGAGCTCTTG AATTCCTTCA TAATAACAAC 360

ATCATTCATC GGGATATAAA ACCAGAGAAC ATTTTAGTTT CCCAGTCTGG GATCACTAAA 420

CTCTGTGATT TTGGCTTTGC TCGGACATTA GCAGCCCCAG GGGACATTTA CACTGACTAT 480

GTGGCTACAC GGTGGTATAG AGCTCCGGAG CTGGTTTTAA AAGACACCAC TTATGGAAAA 540

CCAGTGGATA TTTGGGCTCT GGGCTGTATG ATCATCGAGA TGGCCACCGG AAATCCTTAT 600

CTTCCCAGCA GCTCTGACTT AGACTTGCTG CATAAAATTG TGATTAAAGT AGGCAATTTG 660

ACACCTCATT TGCAGAGTAT TTTTCTAAGG AGCCCTATTT TTTCTGGAGT GGTCCTTCCT 720

CAAGTTCAGC ATCCAAAAAA TGCACGAAAA AAGTATCCCA AGCTCAATGG ATTATTAGCA 780

GATATCGTTC ATGCCTGTTT ACAAATTGAC CCTGAGGACC GAATCTCATC TACAGCTCTC 840

CTGCACCATG ACTATTTTAC CAGAGATGGA TTCATTAAGA AATTCATGCC AGAATTGAGG 900

GCTAAGTTAC AACAAGAAGC AAAAGTAAAT TCAATTAAAA AGCCAAGAGA GAATTTTAAA 960

GACAACGAAC CCATAAAGGA GGAAAGGAAA GCAGTACATG TAAATAAAAT AGCAAATAAT 1020

TTGACAGTGG GAAAGGATAC GGACAAAGGA AAAAAGACCA AGGATGGAAA AGCCAAAGTG 1080

AAAATAAAAG TAGGGAGAGG AGAGATTTCT GAGGCTCAAA AAAATGACCA TGGAAGTGTG 1140

CATTGTCATG GCGATGTGTC TGAGAATTTT CTCCCTCTTC AAGACCTTAA GCCTGCGGAC 1200

ACTGAACTGT TACCCAGCCC CGCAATTCGT AGCGGTGCTA TCATCACTGG TCACTTGAAG 1260

GAAGAAATGC ATCTTGGAGG TTGCATGACA ATGCCCCCGA TCAATCCCAA CAGTAGTAAT 1320

TTGACAACCA CAAGTTTAAA TTACCCACAC AGCAGTACCA GTAATAGGCT ACCTGACAAA 1380

GGCAAAAAGA GACGAAGCCC CTGGCAGACT GGGTGCAACA TTAAGCAGGA GGATGGAACC 1440

TTTACTCAAG TAAGTTCCAA GAAATGA 1467

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++k+tgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKETGQIVAIKIFYEKPE-KSVNKIAMREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+a+ef+h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRALEFLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTTYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q+if ++++f+Gv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVIKVGNLTPHLQSIFLRSPIFSGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dp++r+s++ ll+h+yf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPEDRISSTALLHHDYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KETGQIVAIK IFYEKPEKSV NKIAMREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAL EFLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTTYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VIKVGNLTPH LQSIFLRSPI FSGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPED RISSTALLHH DYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013