EKS-ORA-00049

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-ORA-00049

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	384.9	2.4E-115	174	455	282

Status

Unreviewed

Ensembl Protein

ENSOANP00000004925

UniProt Accession

F6V368;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK16

Gene Synonyms/Alias

CDK16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSOANG00000003108	ENSOANP00000004925	ENSOANT00000004926

Organism

Ornithorhynchus anatinus

Functional Description

Protein Length

505

Protein Sequence
(FASTA)

MDRMKKIKRQ LSMTLRGGRT ADRNSGTEQI NVEESNSSDN GEHPPPAPCG KDPLPRVARG 60

QLRSRAGKKG PAPAFGPRLW VLGSCGESCS EDLLSPDVCL PSTPLRALVH PAPGPSEEPF 120

KDINKRLSLP ADIRLPEGYL EKLTLNSPLF DKPLSRRLRR VSLSEIGFGK LETYVKLDKL 180

GEGTYATVYK GKSKLTDNLV ALKEIRLEHE EGAPCTAIRE VSLLKDLKHA NIVTLHDIIH 240

TDKSLTLVFE YLDKDLKQYL DDCGNIINMH NVKLFLFQLL RGLAYCHRQK VLHRDLKPQN 300

LLINERGELK LADFGLARAK SIPTKTYSNE VVTLWYRPPD ILLGSTDYST QIDMWGVGCI 360

FYEMSTGRPL FPGSTVEEQL HFIFRILGTP TEETWPGILS NEEFKTYNYP KYRPEALLSH 420

APRLDNDGAD LLAKLLQFEG RNRISAEDAM GHQFFHSLGE RVLKLPDTTS IFALKEIQLQ 480

KEMGLRSASL PDSGRSAFRV VDTEF 505

Nucleotide Sequence
(FASTA)

ATGGATCGGA TGAAGAAGAT CAAGCGGCAA CTGTCCATGA CCCTGCGTGG CGGCCGCACG 60

GCCGACAGGA ATAGCGGTAC GGAGCAGATC AACGTCGAGG AGAGTAACAG CAGTGACAAT 120

GGTGAGCACC CGCCCCCTGC CCCTTGCGGG AAAGACCCTC TTCCCCGAGT TGCGCGGGGG 180

CAACTGAGGT CCAGAGCGGG AAAGAAAGGG CCAGCCCCGG CCTTTGGGCC CAGGCTCTGG 240

GTTCTGGGAT CCTGTGGAGA AAGTTGCTCC GAGGATCTAC TCAGTCCAGA TGTCTGCCTG 300

CCTTCCACCC CCCTCCGGGC CTTGGTCCAC CCGGCCCCGG GCCCAAGCGA AGAGCCCTTT 360

AAGGACATCA ACAAGCGCCT GTCGCTGCCG GCTGACATCC GGCTGCCCGA GGGCTACTTG 420

GAGAAGCTGA CGCTCAACAG CCCGCTCTTC GACAAGCCCC TGAGCCGCCG GCTCCGCCGG 480

GTCTCCCTGT CGGAGATTGG CTTCGGGAAG CTGGAGACCT ATGTGAAGCT GGACAAGCTG 540

GGGGAGGGCA CCTATGCCAC CGTGTACAAG GGTAAGAGCA AGTTGACCGA CAACCTGGTG 600

GCTTTGAAAG AGATCCGGTT GGAGCACGAG GAGGGGGCAC CCTGCACCGC CATCCGGGAA 660

GTGTCGCTGC TGAAGGACCT GAAGCACGCC AACATTGTCA CGCTGCATGA CATCATTCAC 720

ACTGACAAGT CCCTCACCCT TGTCTTTGAA TATTTGGACA AGGATCTGAA GCAGTATCTA 780

GATGACTGCG GGAACATCAT CAATATGCAC AATGTGAAGC TGTTCCTGTT CCAGCTGCTC 840

CGAGGGTTGG CGTACTGCCA TAGGCAAAAG GTGCTGCACC GGGATCTCAA GCCGCAGAAC 900

CTGCTCATCA ATGAACGCGG GGAGCTGAAA CTGGCCGACT TCGGTCTGGC CCGAGCCAAG 960

TCCATCCCAA CCAAAACGTA CTCGAACGAG GTGGTGACGC TATGGTACCG ACCCCCCGAC 1020

ATCCTGCTTG GCTCCACGGA CTACTCCACC CAGATCGATA TGTGGGGCGT AGGCTGCATC 1080

TTCTACGAGA TGTCCACGGG CCGCCCTCTT TTCCCTGGCT CCACCGTGGA AGAGCAGCTG 1140

CATTTTATTT TCCGGATCCT GGGCACCCCC ACCGAGGAGA CCTGGCCGGG GATCCTGTCC 1200

AACGAGGAGT TCAAGACCTA CAACTACCCC AAGTACCGGC CCGAAGCCTT GTTGAGTCAC 1260

GCCCCCCGGT TGGACAATGA CGGGGCCGAC CTCTTAGCCA AATTGCTGCA GTTTGAAGGT 1320

CGGAATCGGA TCTCCGCAGA GGACGCCATG GGTCACCAGT TCTTCCACAG TTTGGGGGAG 1380

CGAGTCCTCA AACTTCCCGA CACTACTTCC ATATTTGCAC TAAAGGAGAT TCAGTTACAG 1440

AAGGAGATGG GCCTCCGCTC AGCCTCGCTC CCTGACTCAG GCAGGTCAGC CTTCCGTGTG 1500

GTGGACACCG AGTTCTAG 1518

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 174   YVKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  232

         7899********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ +  +++++vk +l+qll+glay+H++k

Q: 233   VTLHDIIH-TDKSLTLVFEYLDKDLKQYLDDCGN-IINMHNVKLFLFQLLRGLAYCHRQK  290

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 291   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  350

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e+ t +plf+g++  +ql+ if++lgtp+e++wp++ + +e+k +++p

Q: 351   QIDMWGVGCIFYEMSTGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKtYNYP  410

         *******************************************************89***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l++++ dll kll+++ ++Risa++a+ h++f

Q: 411   KYRPEALLSHAPRLDNDGADLLAKLLQFEGRNRISAEDAMGHQFF  455

         *******************************************98

Domain Sequence
(FASTA)

YVKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTDK SLTLVFEYLD KDLKQYLDDC GNIINMHNVK LFLFQLLRGL AYCHRQKVLH 120

RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MSTGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR 240

PEALLSHAPR LDNDGADLLA KLLQFEGRNR ISAEDAMGHQ FF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013